CL2013003556A1 - Compuestos derivados de ftalazinona-pirrolo[3,2-d]pirimidin-carboxamida, inhibidoers de fosfodiesterasa tipo 4 y tipo 5; composcin farmaceutica que o comprende, combinacion fija, no fija y kit, uso del compuesto en la preparacion de un medicamento para trata enfermedaes de las vias respiratorias - Google Patents

Compuestos derivados de ftalazinona-pirrolo[3,2-d]pirimidin-carboxamida, inhibidoers de fosfodiesterasa tipo 4 y tipo 5; composcin farmaceutica que o comprende, combinacion fija, no fija y kit, uso del compuesto en la preparacion de un medicamento para trata enfermedaes de las vias respiratorias

Info

Publication number
CL2013003556A1
CL2013003556A1 CL2013003556A CL2013003556A CL2013003556A1 CL 2013003556 A1 CL2013003556 A1 CL 2013003556A1 CL 2013003556 A CL2013003556 A CL 2013003556A CL 2013003556 A CL2013003556 A CL 2013003556A CL 2013003556 A1 CL2013003556 A1 CL 2013003556A1
Authority
CL
Chile
Prior art keywords
type
fixed
phthalazinone
pyrrolo
pyrimidine
Prior art date
Application number
CL2013003556A
Other languages
English (en)
Spanish (es)
Inventor
Thomas Stengel
Thomas Maier
Alexander Mann
Josef Stadlwieser
Dieter Flockerzi
Andreas Pahl
Ewald Benediktus
Manuela Hessmann
Tobias Kanacher
Ragna Hussong
Christof Zitt
Hans Christof Holst
Rolf Peter Hummel
Martin Viertelhaus
Hermann Tenor
Torsten Dunkern
Armin Hatzelmann
Christian Hesslinger
Original Assignee
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44764312&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013003556(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Gmbh filed Critical Takeda Gmbh
Publication of CL2013003556A1 publication Critical patent/CL2013003556A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2013003556A 2011-06-17 2013-12-11 Compuestos derivados de ftalazinona-pirrolo[3,2-d]pirimidin-carboxamida, inhibidoers de fosfodiesterasa tipo 4 y tipo 5; composcin farmaceutica que o comprende, combinacion fija, no fija y kit, uso del compuesto en la preparacion de un medicamento para trata enfermedaes de las vias respiratorias CL2013003556A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11170440 2011-06-17

Publications (1)

Publication Number Publication Date
CL2013003556A1 true CL2013003556A1 (es) 2014-06-13

Family

ID=44764312

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003556A CL2013003556A1 (es) 2011-06-17 2013-12-11 Compuestos derivados de ftalazinona-pirrolo[3,2-d]pirimidin-carboxamida, inhibidoers de fosfodiesterasa tipo 4 y tipo 5; composcin farmaceutica que o comprende, combinacion fija, no fija y kit, uso del compuesto en la preparacion de un medicamento para trata enfermedaes de las vias respiratorias

Country Status (22)

Country Link
US (2) US20140112945A1 (enExample)
EP (1) EP2721030B1 (enExample)
JP (1) JP5980318B2 (enExample)
KR (1) KR20140037195A (enExample)
CN (1) CN103582644B (enExample)
AR (1) AR086915A1 (enExample)
AU (1) AU2012269133A1 (enExample)
BR (1) BR112013031791A2 (enExample)
CA (1) CA2837248A1 (enExample)
CL (1) CL2013003556A1 (enExample)
CO (1) CO6852074A2 (enExample)
CR (1) CR20130656A (enExample)
DO (1) DOP2013000298A (enExample)
EA (1) EA023713B1 (enExample)
EC (1) ECSP13013076A (enExample)
ES (1) ES2564882T3 (enExample)
MA (1) MA35269B1 (enExample)
MX (1) MX2013014888A (enExample)
PE (1) PE20140648A1 (enExample)
PH (1) PH12013502546A1 (enExample)
TN (1) TN2013000439A1 (enExample)
WO (1) WO2012171900A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018510891A (ja) 2015-04-09 2018-04-19 ガルデルマ・ソシエテ・アノニム 抗菌性インジゴナチュラリス又はインジゴ産生植物抽出物及びその使用
TWI732754B (zh) 2015-04-09 2021-07-11 瑞士商高德美公司 中藥青黛萃取物及其製備方法
TW201642890A (zh) * 2015-04-09 2016-12-16 高德美公司 以青黛或產靛藍植物提取物治療異位性皮膚炎
MX389026B (es) 2015-04-09 2025-03-20 Galderma Sa Una composicion farmaceutica y el uso de la misma.
WO2022006470A1 (en) 2020-07-01 2022-01-06 Vanderbilt University Methods of treatment for a kidney disease

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
EP0407028B2 (en) 1989-05-31 1999-07-07 FISONS plc Medicament inhalation device and formulation
GB8921222D0 (en) 1989-09-20 1989-11-08 Riker Laboratories Inc Medicinal aerosol formulations
IL97065A (en) 1990-02-02 1994-01-25 Fisons Plc Repellent preparations for aerosol
DE4003272A1 (de) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
EP0636362B1 (en) 1990-03-23 1999-12-22 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
EP0553298B1 (en) 1990-10-18 1994-11-17 Minnesota Mining And Manufacturing Company Aerosol formulation comprising beclomethasone 17,21 dipropionate
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
GB9213874D0 (en) 1992-06-30 1992-08-12 Fisons Plc Process to novel medicament form
GB9306703D0 (en) 1993-03-31 1993-05-26 Fisons Plc Inhalation device
IL111194A (en) 1993-10-08 1998-02-08 Fisons Plc Process for the production of medicament formulations
HUP0001541A3 (en) * 1997-01-15 2001-11-28 Altana Pharma Ag Phthalazinone derivatives and pharmaceutical compositions containing them
US6255303B1 (en) * 1998-03-14 2001-07-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone PDE III/IV inhibitors
CA2338680C (en) 1998-08-04 2008-10-14 Jago Research Ag Medicinal aerosol formulations
US6397838B1 (en) 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
JP4530548B2 (ja) 1999-04-23 2010-08-25 バテル・メモリアル・インスティテュート 効率がよい物質移動用電気流体力学式エーロゾル噴霧器およびエーロゾルを生成しかつ所望の位置に給送する方法
WO2000064590A1 (en) 1999-04-23 2000-11-02 Battelle Memorial Institute Directionally controlled ehd aerosol sprayer
NZ522882A (en) * 2000-06-05 2004-07-30 Altana Pharma Bv Pyridazinone compounds effective as beta-2-adrenoreceptor agonists as well as PDE4-inhibitors
ATE320242T1 (de) 2000-10-09 2006-04-15 3M Innovative Properties Co Medizinische aerosolzusammensetzung
EA200300836A1 (ru) * 2001-02-15 2004-02-26 Алтана Фарма Аг Производные фталазинон-пиперидина в качестве ингибиторов pde4
PL363312A1 (en) * 2001-04-25 2004-11-15 Altana Pharma Ag Novel phthalazinones
KR101131684B1 (ko) * 2002-08-10 2012-03-28 니코메드 게엠베하 Ｐｄｅ４ 억제제로서의 피롤리딘디온 치환된피페리딘-프탈라존
JP2005538138A (ja) * 2002-08-10 2005-12-15 アルタナ　ファルマ　アクチエンゲゼルシャフト Ｐｄｅ４インヒビターとしてのピリダジノン誘導体
WO2004018449A1 (en) 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
WO2004062671A2 (en) * 2003-01-14 2004-07-29 Altana Pharma Ag Pde4 inhibitors for the treatment of neoplasms of lymphoid cells
WO2005075457A1 (en) 2004-02-04 2005-08-18 Altana Pharma Ag Phthalazinone-derivatives as pde4 inhibitors
AU2005210042B2 (en) 2004-02-04 2011-04-21 Takeda Gmbh 2-(piperidin-4-yl) -4, 5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
AR070454A1 (es) * 2008-02-27 2010-04-07 Nycomed Gmbh Pirrolopirimidincarboxamidas y composiciones farmaceuticas que las comprenden
AR077898A1 (es) 2009-08-26 2011-09-28 Nycomed Gmbh Metilpirrolopirimidincarboxamidas

Also Published As

Publication number Publication date
CA2837248A1 (en) 2012-12-20
EP2721030B1 (en) 2015-12-16
MA35269B1 (fr) 2014-07-03
AU2012269133A1 (en) 2014-01-30
BR112013031791A2 (pt) 2017-01-31
CN103582644B (zh) 2016-07-20
JP5980318B2 (ja) 2016-08-31
TN2013000439A1 (en) 2015-03-30
EA023713B1 (ru) 2016-07-29
WO2012171900A1 (en) 2012-12-20
JP2014517021A (ja) 2014-07-17
PE20140648A1 (es) 2014-05-30
AR086915A1 (es) 2014-01-29
US20140112945A1 (en) 2014-04-24
EA201400001A1 (ru) 2014-05-30
EP2721030A1 (en) 2014-04-23
PH12013502546A1 (en) 2014-01-27
ECSP13013076A (es) 2014-01-31
DOP2013000298A (es) 2014-03-31
MX2013014888A (es) 2014-02-27
ES2564882T3 (es) 2016-03-29
US20160108049A1 (en) 2016-04-21
CO6852074A2 (es) 2014-01-30
CR20130656A (es) 2014-02-18
CN103582644A (zh) 2014-02-12
KR20140037195A (ko) 2014-03-26

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