BRPI1009781A2 - compostos para o tratamento de distúrbios metabólicos, composição farmacêutica que os compreende e uso dos mesmos - Google Patents

compostos para o tratamento de distúrbios metabólicos, composição farmacêutica que os compreende e uso dos mesmos

Info

Publication number
BRPI1009781A2
BRPI1009781A2 BRPI1009781A BRPI1009781A BRPI1009781A2 BR PI1009781 A2 BRPI1009781 A2 BR PI1009781A2 BR PI1009781 A BRPI1009781 A BR PI1009781A BR PI1009781 A BRPI1009781 A BR PI1009781A BR PI1009781 A2 BRPI1009781 A2 BR PI1009781A2
Authority
BR
Brazil
Prior art keywords
compounds
treatment
pharmaceutical compositions
metabolic disorders
metabolic
Prior art date
Application number
BRPI1009781A
Other languages
English (en)
Inventor
Alan John William Stewart
David Matthew Withall
Karen Lesley Schofield
Matthew Colin Thor Fyfe
Oscar Barba
Revathy Perpetua Jeevaratnam
Simon Andrew Swain
Susan Helen Davis
Thomas Staroske
Original Assignee
Prosidion Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prosidion Ltd filed Critical Prosidion Ltd
Publication of BRPI1009781A2 publication Critical patent/BRPI1009781A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
BRPI1009781A 2009-03-12 2010-03-12 compostos para o tratamento de distúrbios metabólicos, composição farmacêutica que os compreende e uso dos mesmos BRPI1009781A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0904287.0A GB0904287D0 (en) 2009-03-12 2009-03-12 Compounds for the treatment of metabolic disorders
PCT/GB2010/050442 WO2010103335A1 (en) 2009-03-12 2010-03-12 Compounds for the treatment of metabolic disorders

Publications (1)

Publication Number Publication Date
BRPI1009781A2 true BRPI1009781A2 (pt) 2016-03-08

Family

ID=40600949

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009781A BRPI1009781A2 (pt) 2009-03-12 2010-03-12 compostos para o tratamento de distúrbios metabólicos, composição farmacêutica que os compreende e uso dos mesmos

Country Status (18)

Country Link
US (1) US20120040953A1 (pt)
EP (1) EP2406256A1 (pt)
JP (1) JP2012520284A (pt)
KR (1) KR20110130476A (pt)
CN (1) CN102395584A (pt)
AU (1) AU2010222673A1 (pt)
BR (1) BRPI1009781A2 (pt)
CA (1) CA2754794A1 (pt)
CL (1) CL2011002221A1 (pt)
EA (1) EA201190209A1 (pt)
GB (1) GB0904287D0 (pt)
IL (1) IL215051A0 (pt)
MA (1) MA33242B1 (pt)
MX (1) MX2011009491A (pt)
PE (1) PE20120356A1 (pt)
SG (1) SG174362A1 (pt)
WO (1) WO2010103335A1 (pt)
ZA (1) ZA201107446B (pt)

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NZ596445A (en) 2009-06-24 2013-04-26 Boehringer Ingelheim Int New compounds, pharmaceutical composition and methods relating thereto
JP2012530758A (ja) 2009-06-24 2012-12-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規化合物、医薬組成物及びそれに関する方法
WO2011113947A1 (en) 2010-03-18 2011-09-22 Boehringer Ingelheim International Gmbh Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions
GB201006167D0 (en) * 2010-04-14 2010-05-26 Prosidion Ltd Compounds for the treatment of metabolic disorders
GB2488360A (en) * 2011-02-25 2012-08-29 Prosidion Ltd Heterocyclic GPCR agonists
GB201114389D0 (en) * 2011-08-22 2011-10-05 Prosidion Ltd Novel compounds
AR083904A1 (es) * 2010-11-18 2013-04-10 Prosidion Ltd Derivados de 1,4-pirrolidinas disustituidos y 3-il-aminas y sus usos en el tratamiento de desordenes metabolicos
WO2012170867A1 (en) 2011-06-09 2012-12-13 Rhizen Pharmaceuticals Sa Novel compounds as modulators of gpr-119
KR101881932B1 (ko) 2011-12-07 2018-07-27 삼성전자주식회사 자기 소자 및 그 제조 방법
JP2015522080A (ja) 2012-07-11 2015-08-03 エルセリクス セラピューティクス インコーポレイテッド スタチン、ビグアナイド、およびさらなる薬剤を含む心血管代謝性リスクを減少させるための組成物
WO2018165520A1 (en) * 2017-03-10 2018-09-13 Vps-3, Inc. Metalloenzyme inhibitor compounds
WO2021009209A1 (en) * 2019-07-15 2021-01-21 Oncoarendi Therapeutics S.A. Substituted amino triazoles useful as chitinase inhibitors

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GB9719496D0 (en) 1997-09-13 1997-11-19 Glaxo Group Ltd G protien chimeras
JP2002523090A (ja) 1998-09-01 2002-07-30 ビーエーエスエフ アクチェンゲゼルシャフト 異種ｇタンパク質共役受容体の増強された機能的発現
US6221660B1 (en) 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
NZ547965A (en) * 2003-12-24 2009-12-24 Prosidion Ltd 1,2,4-Oxadiazole derivatives as GPCR receptor agonists
CA2591922A1 (en) 2004-12-24 2006-06-29 Prosidion Limited G-protein coupled receptor (gpr116) agonists and use thereof for treating obesity and diabetes
US8193359B2 (en) 2004-12-24 2012-06-05 Prosidion Limited G-protein coupled receptor agonists
GB0428514D0 (en) 2004-12-31 2005-02-09 Prosidion Ltd Compounds
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EP1907384A2 (en) 2005-06-30 2008-04-09 Prosidion Limited Gpcr agonists
JP5114395B2 (ja) 2005-06-30 2013-01-09 プロシディオン・リミテッド Ｇｐｃｒアゴニスト
GB0513257D0 (en) * 2005-06-30 2005-08-03 Prosidion Ltd Compounds
BRPI0613505A2 (pt) 2005-06-30 2011-01-11 Prosidion Ltd agonistas de gpcr
CN101379028A (zh) 2006-02-09 2009-03-04 阿斯利康(瑞典)有限公司 化学化合物
MX2008012814A (es) 2006-04-06 2008-10-17 Prosidion Ltd Agonistas del receptor acoplado a la proteina g heterociclicos.
GB0607196D0 (en) 2006-04-11 2006-05-17 Prosidion Ltd G-protein coupled receptor agonists
GB0610746D0 (en) 2006-06-01 2006-07-12 Prosidion Ltd Method of treatment
WO2007148185A2 (en) 2006-06-21 2007-12-27 Pfizer Products Inc. Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors
ES2374952T3 (es) 2006-12-06 2012-02-23 Glaxosmithkline Llc Compuestos bicíclicos y uso como antidiabéticos.
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PT2114933E (pt) 2007-01-04 2011-12-20 Prosidion Ltd Agonistas do gpcr de piperidina
CA2674360A1 (en) 2007-01-04 2008-07-10 Prosidion Limited Piperidine gpcr agonists
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EP2200609A1 (en) 2007-09-10 2010-06-30 Prosidion Limited Compounds for the treatment of metabolic disorders
JP4455675B2 (ja) 2007-10-18 2010-04-21 日鉱金属株式会社 金属被覆ポリイミド複合体及び同複合体の製造方法並びに電子回路基板の製造方法
GB0720389D0 (en) 2007-10-18 2008-11-12 Prosidion Ltd G-Protein Coupled Receptor Agonists
CN101621337B (zh) 2008-06-30 2013-08-07 华为技术有限公司 一种时延调节装置与方法
KR20110036609A (ko) 2008-07-10 2011-04-07 프로시디온 리미티드 피페리디닐 ｇｐｃｒ 작용제
GB0812641D0 (en) 2008-07-10 2008-08-20 Prosidion Ltd Compounds
GB0812648D0 (en) 2008-07-10 2008-08-20 Prosidion Ltd Compounds
ATE557024T1 (de) 2008-07-10 2012-05-15 Prosidion Ltd Piperidinverbindungen als gpcr-agonisten

Also Published As

Publication number Publication date
KR20110130476A (ko) 2011-12-05
IL215051A0 (en) 2011-11-30
GB0904287D0 (en) 2009-04-22
US20120040953A1 (en) 2012-02-16
JP2012520284A (ja) 2012-09-06
EP2406256A1 (en) 2012-01-18
CA2754794A1 (en) 2010-09-16
EA201190209A1 (ru) 2012-04-30
ZA201107446B (en) 2012-06-27
MA33242B1 (fr) 2012-05-02
PE20120356A1 (es) 2012-04-16
CL2011002221A1 (es) 2012-07-06
MX2011009491A (es) 2011-10-11
AU2010222673A1 (en) 2011-11-03
SG174362A1 (en) 2011-11-28
CN102395584A (zh) 2012-03-28
WO2010103335A1 (en) 2010-09-16

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]