MA34520B1 - Anticorps se liant à la myostatine, compositions et procédés - Google Patents
Anticorps se liant à la myostatine, compositions et procédésInfo
- Publication number
- MA34520B1 MA34520B1 MA35726A MA35726A MA34520B1 MA 34520 B1 MA34520 B1 MA 34520B1 MA 35726 A MA35726 A MA 35726A MA 35726 A MA35726 A MA 35726A MA 34520 B1 MA34520 B1 MA 34520B1
- Authority
- MA
- Morocco
- Prior art keywords
- methods
- compositions
- binding antibodies
- myostatin binding
- antibodies
- Prior art date
Links
- 102000004472 Myostatin Human genes 0.000 title abstract 2
- 108010056852 Myostatin Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Microbiology (AREA)
Abstract
La présente invention concerne des antagonistes sélectifs de la myostatine (y compris des anticorps), des acides nucléiques codant pour ces derniers et des procédés permettant de les fabriquer et de les utiliser. Anticorps neutralisants reconnaissant l'épitope conformationnel proche de la position 21 à 31 et de la position 50 à 60.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37409510P | 2010-08-16 | 2010-08-16 | |
PCT/US2011/047806 WO2012024242A1 (fr) | 2010-08-16 | 2011-08-15 | Anticorps se liant à la myostatine, compositions et procédés |
Publications (1)
Publication Number | Publication Date |
---|---|
MA34520B1 true MA34520B1 (fr) | 2013-09-02 |
Family
ID=44583430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA35726A MA34520B1 (fr) | 2010-08-16 | 2011-08-15 | Anticorps se liant à la myostatine, compositions et procédés |
Country Status (17)
Country | Link |
---|---|
US (2) | US8999343B2 (fr) |
EP (1) | EP2606066A1 (fr) |
JP (2) | JP2013537425A (fr) |
KR (1) | KR20140005864A (fr) |
CN (2) | CN103221426B (fr) |
AU (2) | AU2011292197B2 (fr) |
CA (1) | CA2808382A1 (fr) |
CL (1) | CL2013000460A1 (fr) |
CO (1) | CO6690763A2 (fr) |
CR (1) | CR20130112A (fr) |
EA (1) | EA201390242A1 (fr) |
MA (1) | MA34520B1 (fr) |
MX (1) | MX2013001845A (fr) |
NZ (1) | NZ608206A (fr) |
PE (1) | PE20131340A1 (fr) |
SG (2) | SG187867A1 (fr) |
WO (1) | WO2012024242A1 (fr) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
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DK2006381T3 (en) | 2006-03-31 | 2016-02-22 | Chugai Pharmaceutical Co Ltd | PROCEDURE FOR REGULATING ANTIBODIES BLOOD PHARMACOKINETICS |
HUE029635T2 (en) | 2007-09-26 | 2017-03-28 | Chugai Pharmaceutical Co Ltd | A method for modifying an isoelectric point of an antibody by amino acid substitution in CDR |
DK2708559T3 (en) | 2008-04-11 | 2018-06-14 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule capable of repeatedly binding two or more antigen molecules |
CA2808382A1 (fr) | 2010-08-16 | 2012-02-23 | Amgen Inc. | Anticorps se liant a la myostatine, compositions et procedes |
TWI812066B (zh) | 2010-11-30 | 2023-08-11 | 日商中外製藥股份有限公司 | 具有鈣依存性的抗原結合能力之抗體 |
US8871209B2 (en) | 2011-11-14 | 2014-10-28 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for increasing muscle mass and muscle strength by specifically antagonizing GDF8 and or Activin A |
JP6774164B2 (ja) | 2012-08-24 | 2020-10-21 | 中外製薬株式会社 | マウスFcγRII特異的Fc抗体 |
EP3721900A1 (fr) | 2012-08-24 | 2020-10-14 | Chugai Seiyaku Kabushiki Kaisha | Variant de région fc spécifique au fcgammariib |
PL2895503T3 (pl) | 2012-09-13 | 2019-09-30 | Bristol-Myers Squibb Company | Oparte na fibronektynie białka z domeną rusztowania, które wiążą się z miostatyną |
TWI636062B (zh) | 2013-04-02 | 2018-09-21 | 中外製藥股份有限公司 | Fc region variant |
AU2014262843B2 (en) | 2013-05-06 | 2017-06-22 | Scholar Rock, Inc. | Compositions and methods for growth factor modulation |
EP2853898B1 (fr) | 2013-09-27 | 2017-01-04 | Medizinische Hochschule Hannover | Analyse de la myostatine dans le sérum |
KR102446386B1 (ko) | 2014-01-10 | 2022-09-22 | 아납티스바이오, 아이엔씨. | 인터루킨-33 (il-33)에 대한 항체 |
RU2016138744A (ru) * | 2014-04-10 | 2018-05-11 | Оби Фарма Инк. | Антитела, фармацевтические композиции и их применения |
WO2016073906A2 (fr) * | 2014-11-06 | 2016-05-12 | Scholar Rock, Inc. | Immunoessais liés à des facteurs de croissance transformants |
AU2015342936B2 (en) | 2014-11-06 | 2020-10-08 | Scholar Rock, Inc. | Anti-pro/latent-Myostatin antibodies and uses thereof |
TWI695068B (zh) | 2014-11-24 | 2020-06-01 | 美商身體邏輯股份有限公司 | 用於結合生長分化因子11的核酸化合物 |
TWI779010B (zh) * | 2014-12-19 | 2022-10-01 | 日商中外製藥股份有限公司 | 抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法 |
EP3253778A1 (fr) | 2015-02-05 | 2017-12-13 | Chugai Seiyaku Kabushiki Kaisha | Anticorps comprenant un domaine se liant à l'antigène dépendant de la concentration d'ions, variants de la région fc, anticorps se liant à l'il-8, et leurs utilisations |
MA41919A (fr) * | 2015-04-06 | 2018-02-13 | Acceleron Pharma Inc | Hétéromultimères alk4:actriib et leurs utilisations |
CN107771081A (zh) | 2015-04-15 | 2018-03-06 | 瑞泽恩制药公司 | 用gdf8抑制剂增加力量和功能的方法 |
IL258121B2 (en) * | 2015-09-15 | 2024-01-01 | Scholar Rock Inc | Antipro/latent myostatin antibodies and their uses |
EP3394098A4 (fr) | 2015-12-25 | 2019-11-13 | Chugai Seiyaku Kabushiki Kaisha | Anticorps anti-myostatine et procédés d'utilisation |
CN115814077A (zh) | 2016-01-08 | 2023-03-21 | 供石公司 | 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法 |
ES2981471T3 (es) * | 2016-04-25 | 2024-10-09 | Five Prime Therapeutics Inc | NOPE para el tratamiento de la pérdida de masa muscular y la debilidad muscular patológicas |
KR20230169484A (ko) | 2016-06-13 | 2023-12-15 | 스칼러 락, 인크. | 미오스타틴 억제제의 용도 및 조합 요법 |
KR102538749B1 (ko) | 2016-08-05 | 2023-06-01 | 추가이 세이야쿠 가부시키가이샤 | Il-8 관련 질환의 치료용 또는 예방용 조성물 |
BR112019006993A2 (pt) | 2016-10-05 | 2019-09-03 | Acceleron Pharma Inc | heteromultímeros de alk4:actriib e usos dos mesmos |
RS64159B1 (sr) * | 2017-01-06 | 2023-05-31 | Scholar Rock Inc | Tretiranje metaboličkih bolesti inhibiranjem aktivacije miostatina |
EP3606562A4 (fr) * | 2017-04-03 | 2020-11-11 | Acceleron Pharma Inc. | Compositions et méthodes destinées au traitement de l'amyotrophie spinale |
EA202092064A1 (ru) | 2018-03-01 | 2020-12-21 | Ридженерон Фармасьютикалз, Инк. | Способы изменения состава тела |
CN111793123B (zh) * | 2019-04-08 | 2022-03-08 | 中国农业大学 | 一种肌肉生长抑制素mstn的突变体及其应用 |
WO2021060880A1 (fr) * | 2019-09-24 | 2021-04-01 | 마이오텍사이언스 주식회사 | Composition pharmaceutique pour la prévention ou le traitement de la sarcopénie contenant un acide aminé non naturel |
CN114891101B (zh) * | 2021-12-02 | 2023-06-16 | 吉林省农业科学院 | 一种牛肌肉生长抑制素蛋白单克隆抗体及其应用 |
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-
2011
- 2011-08-15 CA CA2808382A patent/CA2808382A1/fr not_active Abandoned
- 2011-08-15 SG SG2013011564A patent/SG187867A1/en unknown
- 2011-08-15 EA EA201390242A patent/EA201390242A1/ru unknown
- 2011-08-15 SG SG10201506405YA patent/SG10201506405YA/en unknown
- 2011-08-15 MA MA35726A patent/MA34520B1/fr unknown
- 2011-08-15 NZ NZ608206A patent/NZ608206A/en not_active IP Right Cessation
- 2011-08-15 WO PCT/US2011/047806 patent/WO2012024242A1/fr active Application Filing
- 2011-08-15 CN CN201180044739.7A patent/CN103221426B/zh not_active Expired - Fee Related
- 2011-08-15 PE PE2013000298A patent/PE20131340A1/es not_active Application Discontinuation
- 2011-08-15 US US13/816,894 patent/US8999343B2/en not_active Expired - Fee Related
- 2011-08-15 KR KR1020137006764A patent/KR20140005864A/ko not_active Application Discontinuation
- 2011-08-15 AU AU2011292197A patent/AU2011292197B2/en not_active Ceased
- 2011-08-15 EP EP11745910.7A patent/EP2606066A1/fr not_active Withdrawn
- 2011-08-15 JP JP2013524918A patent/JP2013537425A/ja active Pending
- 2011-08-15 CN CN201510954088.5A patent/CN105440134A/zh active Pending
- 2011-08-15 MX MX2013001845A patent/MX2013001845A/es not_active Application Discontinuation
-
2013
- 2013-02-15 CL CL2013000460A patent/CL2013000460A1/es unknown
- 2013-03-11 CO CO13047993A patent/CO6690763A2/es unknown
- 2013-03-13 CR CR20130112A patent/CR20130112A/es unknown
-
2015
- 2015-03-19 US US14/663,377 patent/US20150322144A1/en not_active Abandoned
- 2015-08-26 AU AU2015218478A patent/AU2015218478A1/en not_active Abandoned
-
2016
- 2016-05-27 JP JP2016105716A patent/JP2016198098A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2013001845A (es) | 2013-08-27 |
US8999343B2 (en) | 2015-04-07 |
US20150322144A1 (en) | 2015-11-12 |
JP2016198098A (ja) | 2016-12-01 |
NZ608206A (en) | 2015-02-27 |
PE20131340A1 (es) | 2013-11-29 |
CN105440134A (zh) | 2016-03-30 |
EP2606066A1 (fr) | 2013-06-26 |
SG10201506405YA (en) | 2015-10-29 |
CL2013000460A1 (es) | 2014-03-28 |
AU2015218478A1 (en) | 2015-09-17 |
AU2011292197A1 (en) | 2013-04-04 |
KR20140005864A (ko) | 2014-01-15 |
CN103221426A (zh) | 2013-07-24 |
SG187867A1 (en) | 2013-03-28 |
CA2808382A1 (fr) | 2012-02-23 |
WO2012024242A1 (fr) | 2012-02-23 |
JP2013537425A (ja) | 2013-10-03 |
EA201390242A1 (ru) | 2013-07-30 |
CN103221426B (zh) | 2016-01-13 |
CR20130112A (es) | 2013-05-15 |
CO6690763A2 (es) | 2013-06-17 |
US20130209489A1 (en) | 2013-08-15 |
AU2011292197B2 (en) | 2015-05-28 |
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