MX356279B - Métodos para el tratamiento de soriasis usando antagonistas de il-17. - Google Patents
Métodos para el tratamiento de soriasis usando antagonistas de il-17.Info
- Publication number
- MX356279B MX356279B MX2013003916A MX2013003916A MX356279B MX 356279 B MX356279 B MX 356279B MX 2013003916 A MX2013003916 A MX 2013003916A MX 2013003916 A MX2013003916 A MX 2013003916A MX 356279 B MX356279 B MX 356279B
- Authority
- MX
- Mexico
- Prior art keywords
- treating psoriasis
- antagonists
- methods
- antibody
- binding molecule
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a el uso de secukinumab en la preparación de un medicamento para tratar psoriasis, en donde el secukinumab: a) está adaptado para ser administrable a un paciente que necesita del mismo durante un régimen de inducción, en donde el régimen de inducción comprende un régimen de carga, en donde el régimen de carga comprende cinco dosis subcutáneas de 150 mg a 300 mg de secukinumab, cada una de las cinco dosis semanalmente, empezando en la semana cero: y b) posteriormente, está adaptado para ser administrable durante un régimen de mantenimiento, en donde el régimen de mantenimiento comprende dosis subcutáneas de 150 mg a 300 mg de secukinumab cada cuatro semanas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39138810P | 2010-10-08 | 2010-10-08 | |
| PCT/EP2011/067522 WO2012045848A1 (en) | 2010-10-08 | 2011-10-07 | Methods of treating psoriasis using il-17 antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013003916A MX2013003916A (es) | 2013-06-03 |
| MX356279B true MX356279B (es) | 2018-05-22 |
Family
ID=44759699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013003916A MX356279B (es) | 2010-10-08 | 2011-10-07 | Métodos para el tratamiento de soriasis usando antagonistas de il-17. |
Country Status (28)
| Country | Link |
|---|---|
| US (9) | US9717791B2 (es) |
| EP (5) | EP3299390A1 (es) |
| JP (2) | JP5537740B2 (es) |
| KR (3) | KR20150018595A (es) |
| CN (2) | CN107029234A (es) |
| AU (1) | AU2011311482B2 (es) |
| BR (1) | BR112013008501A2 (es) |
| CA (1) | CA2813900C (es) |
| CL (1) | CL2013000930A1 (es) |
| CY (1) | CY1119942T1 (es) |
| DK (1) | DK2625199T3 (es) |
| ES (1) | ES2660770T3 (es) |
| HK (1) | HK1247932A1 (es) |
| HR (1) | HRP20180301T1 (es) |
| HU (1) | HUE038334T2 (es) |
| IL (1) | IL225310A (es) |
| LT (1) | LT2625199T (es) |
| MA (1) | MA34646B1 (es) |
| MX (1) | MX356279B (es) |
| NO (1) | NO2625199T3 (es) |
| PH (1) | PH12013500660B1 (es) |
| PL (1) | PL2625199T3 (es) |
| PT (1) | PT2625199T (es) |
| RU (2) | RU2591083C2 (es) |
| SG (1) | SG188979A1 (es) |
| SI (1) | SI2625199T1 (es) |
| TW (2) | TWI564022B (es) |
| WO (1) | WO2012045848A1 (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| EA031209B9 (ru) | 2010-01-15 | 2021-11-19 | Кирин-Эмджен, Инк. | Фармацевтический состав антитела для лечения воспалительного заболевания и способы его применения |
| AU2011254557B2 (en) | 2010-05-20 | 2015-09-03 | Ablynx Nv | Biological materials related to HER3 |
| PT2625199T (pt) | 2010-10-08 | 2018-02-28 | Novartis Ag | Métodos de tratamento de psoríase usando antagonistas de il-17 |
| BR112013011176A2 (pt) | 2010-11-05 | 2020-09-01 | Novartis Ag | métodos de tratamento de artrite reumatoide usando antagonistas de il-17 |
| UA117218C2 (uk) | 2011-05-05 | 2018-07-10 | Мерк Патент Гмбх | Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f |
| AU2012341081B2 (en) * | 2011-11-21 | 2015-06-04 | Novartis Ag | Methods of treating psoriatic arthritis (PsA) using IL-17 antagonists and PsA response or non- response alleles |
| EP3689369A1 (en) * | 2013-03-15 | 2020-08-05 | Amgen, Inc | Methods for treating psoriasis using an anti-il-23 antibody |
| WO2014143540A1 (en) * | 2013-03-15 | 2014-09-18 | Amgen Inc. | Methods for treating crohn's disease using an anti-il23 antibody |
| US10434172B2 (en) | 2013-08-15 | 2019-10-08 | Novartis Ag | Methods of treating generalized pustular psoriasis (GPP) using IL-17 antagonists |
| KR101836756B1 (ko) | 2013-12-27 | 2018-03-08 | 오사카 유니버시티 | Il-17a를 표적화하는 백신 |
| RU2577228C2 (ru) * | 2014-03-14 | 2016-03-10 | Закрытое Акционерное Общество "Биокад" | Анти-il-17-антитела, способ их получения и способ применения |
| MY184189A (en) * | 2014-03-31 | 2021-03-24 | Amgen K A Inc | Methods of treating nail and scalp psoriasis |
| CA2949236C (en) | 2014-05-15 | 2023-06-13 | Incube Labs, Llc | Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins |
| US11548940B2 (en) | 2014-05-15 | 2023-01-10 | Rani Therapeutics, Llc | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| WO2016031250A1 (en) * | 2014-08-26 | 2016-03-03 | Kirin-Amgen, Inc. | Method for treating psoriasis patient which received anti-tnf-alpha antibody therapy |
| SMT202400285T1 (it) * | 2014-09-10 | 2024-09-16 | Novartis Ag | Uso di antagonisti di il-17 per inibire la progressione del danno strutturale in pazienti affetti da artrite psoriasica |
| AR103172A1 (es) * | 2014-12-22 | 2017-04-19 | Novartis Ag | Reducción selectiva de residuos de cisteina en anticuerpos il-17 |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| CA2978431C (en) | 2015-03-02 | 2023-10-24 | 180 Therapeutics Lp | Method of treating a localized fibrotic disorder using a tnf receptor 2 antagonist |
| EP3167892A1 (en) | 2015-11-10 | 2017-05-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for preventing or treating imflammatory bowel diseases |
| RU2754683C2 (ru) * | 2015-10-27 | 2021-09-06 | Юсб Биофарма Срл | Способы лечения с использованием анти-il-17a антител |
| WO2018015880A1 (en) | 2016-07-19 | 2018-01-25 | Novartis Ag | Methods of treating new-onset plaque type psoriasis using il-17 antagonists |
| WO2018096467A1 (en) * | 2016-11-28 | 2018-05-31 | Novartis Ag | Methods of treating acne using interleukin-17 (il-17) antagonists |
| WO2018158741A1 (en) * | 2017-03-03 | 2018-09-07 | Novartis Ag | Psoriasis disease modification following long-term treatment with an il-17 antagonist |
| EP3672988A1 (en) * | 2017-08-23 | 2020-07-01 | Eli Lilly and Company | Treatment of genital psoriasis |
| TWI808397B (zh) * | 2018-09-11 | 2023-07-11 | 美商美國禮來大藥廠 | 治療牛皮癬之方法 |
| EP4006053A4 (en) | 2019-07-30 | 2022-10-26 | Jiangsu Hengrui Medicine Co., Ltd. | METHOD OF TREATMENT OF AUTOIMMUNE DISEASE BY IL-17 ANTAGONISTS |
| BR112022004941A2 (pt) | 2019-09-20 | 2022-06-28 | Novartis Ag | Métodos para tratar doenças autoimunes com o uso de antagonistas de interleucina-17 (il-17) |
| WO2022127842A1 (zh) * | 2020-12-17 | 2022-06-23 | 上海华奥泰生物药业股份有限公司 | 靶向il-17a和il-36r的双特异性抗体及其应用 |
| TW202246329A (zh) * | 2021-03-03 | 2022-12-01 | 大陸商蘇州盛迪亞生物醫藥有限公司 | 抗il-17抗體治療自體免疫性疾病和炎症的方法 |
| WO2023186174A1 (en) * | 2022-04-01 | 2023-10-05 | Zai Lab (Shanghai) Co., Ltd. | Topical formulation comprising an il-17a binding molecule and uses thereof |
| CN116593718B (zh) * | 2023-07-18 | 2023-09-15 | 军科正源(北京)药物研究有限责任公司 | 用于检测司库奇尤单抗抗药性抗体的试剂 |
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| RU2430110C2 (ru) | 2006-01-31 | 2011-09-27 | Новартис Аг | Антитела - антагонисты интерлейкина-17 (ил-17) для лечения рака |
| TW200815469A (en) | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
| EA200970250A1 (ru) | 2006-09-05 | 2010-02-26 | Медарекс, Инк. | Антитела к костным морфогенетическим белкам и их рецепторам и способы их применения |
| US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
| RU2367429C2 (ru) | 2007-01-30 | 2009-09-20 | Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН | Способ лечения псориаза |
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| BRPI0915448A2 (pt) | 2008-07-08 | 2015-11-10 | Abbott Lab | imunoglobulinas de domínio variável duplo para prostaglandina e2 e usos das mesmas |
| KR101318549B1 (ko) * | 2008-09-29 | 2013-10-16 | 로슈 글리카트 아게 | 인간 il17 에 대한 항체 및 이의 용도 |
| BRPI0921845A2 (pt) | 2008-11-12 | 2019-09-17 | Medimmune Llc | formulação aquosa estéril estável, forma de dosagem unitária farmacêutica, seringa pré-carregada, e, métodos para tratar uma doença ou distúrbio, para tratar ou prevenir rejeição, para esgotar células t que expressam icos em um paciente humano, e para interromper arquitetura central germinal em um órgão linfóide secundário de um primata |
| US20110256130A1 (en) | 2008-12-01 | 2011-10-20 | Joshua Robert Schultz | Methods of treating inflammatory disorders |
| SG173705A1 (en) | 2009-03-05 | 2011-09-29 | Abbott Lab | Il-17 binding proteins |
| PT2625199T (pt) | 2010-10-08 | 2018-02-28 | Novartis Ag | Métodos de tratamento de psoríase usando antagonistas de il-17 |
| BR112013011176A2 (pt) | 2010-11-05 | 2020-09-01 | Novartis Ag | métodos de tratamento de artrite reumatoide usando antagonistas de il-17 |
| AR084234A1 (es) | 2010-12-13 | 2013-05-02 | Novartis Ag | Metodos predictivos y metodos para tratar artritis usando antagonistas de interleuquina 17 (il-17) |
| AU2012341081B2 (en) | 2011-11-21 | 2015-06-04 | Novartis Ag | Methods of treating psoriatic arthritis (PsA) using IL-17 antagonists and PsA response or non- response alleles |
| JP2015519311A (ja) | 2012-04-20 | 2015-07-09 | ノバルティス アーゲー | Il−17アンタゴニストを用いて強直性脊椎炎を治療する方法 |
| WO2014155278A2 (en) | 2013-03-26 | 2014-10-02 | Novartis Ag | Methods of treating autoimmune diseases using il-17 antagonists |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| IL257723B2 (en) | 2015-10-19 | 2023-04-01 | Novartis Ag | Methods for the treatment of non-radiographic sclerosing spondylitis with the help of interleukin-17 (il-17) antagonists |
| US11280479B2 (en) | 2017-10-18 | 2022-03-22 | The Sloan Company | Sign box light module |
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2011
- 2011-10-07 PT PT117647644T patent/PT2625199T/pt unknown
- 2011-10-07 HR HRP20180301TT patent/HRP20180301T1/hr unknown
- 2011-10-07 CN CN201710261381.2A patent/CN107029234A/zh active Pending
- 2011-10-07 RU RU2013120957/15A patent/RU2591083C2/ru active
- 2011-10-07 EP EP17195148.6A patent/EP3299390A1/en not_active Withdrawn
- 2011-10-07 CN CN2011800487322A patent/CN103154031A/zh active Pending
- 2011-10-07 CA CA2813900A patent/CA2813900C/en active Active
- 2011-10-07 TW TW105116323A patent/TWI564022B/zh active
- 2011-10-07 KR KR1020147036815A patent/KR20150018595A/ko not_active Withdrawn
- 2011-10-07 KR KR1020147018691A patent/KR101620771B1/ko active Active
- 2011-10-07 DK DK11764764.4T patent/DK2625199T3/en active
- 2011-10-07 KR KR1020137011792A patent/KR20130110179A/ko not_active Ceased
- 2011-10-07 EP EP22186296.4A patent/EP4137514A1/en active Pending
- 2011-10-07 HU HUE11764764A patent/HUE038334T2/hu unknown
- 2011-10-07 US US13/876,367 patent/US9717791B2/en active Active
- 2011-10-07 ES ES11764764.4T patent/ES2660770T3/es active Active
- 2011-10-07 PH PH1/2013/500660A patent/PH12013500660B1/en unknown
- 2011-10-07 EP EP25216056.9A patent/EP4670788A3/en active Pending
- 2011-10-07 BR BR112013008501A patent/BR112013008501A2/pt active Search and Examination
- 2011-10-07 SG SG2013018486A patent/SG188979A1/en unknown
- 2011-10-07 SI SI201131408T patent/SI2625199T1/en unknown
- 2011-10-07 NO NO11764764A patent/NO2625199T3/no unknown
- 2011-10-07 EP EP11764764.4A patent/EP2625199B1/en active Active
- 2011-10-07 MX MX2013003916A patent/MX356279B/es active IP Right Grant
- 2011-10-07 RU RU2016120615A patent/RU2665954C1/ru active
- 2011-10-07 LT LTEP11764764.4T patent/LT2625199T/lt unknown
- 2011-10-07 AU AU2011311482A patent/AU2011311482B2/en active Active
- 2011-10-07 JP JP2013532213A patent/JP5537740B2/ja active Active
- 2011-10-07 IL IL225310A patent/IL225310A/en active IP Right Grant
- 2011-10-07 EP EP20187002.9A patent/EP3792281A1/en not_active Ceased
- 2011-10-07 WO PCT/EP2011/067522 patent/WO2012045848A1/en not_active Ceased
- 2011-10-07 PL PL11764764T patent/PL2625199T3/pl unknown
- 2011-10-07 TW TW100136608A patent/TWI548419B/zh active
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2013
- 2013-04-05 CL CL2013000930A patent/CL2013000930A1/es unknown
- 2013-05-03 MA MA35872A patent/MA34646B1/fr unknown
- 2013-12-09 JP JP2013253745A patent/JP2014114288A/ja not_active Withdrawn
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2017
- 2017-06-22 US US15/630,577 patent/US10583190B2/en active Active
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2018
- 2018-02-22 CY CY20181100220T patent/CY1119942T1/el unknown
- 2018-06-01 HK HK18107225.2A patent/HK1247932A1/en unknown
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2019
- 2019-12-19 US US16/720,351 patent/US11534490B2/en active Active
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2020
- 2020-12-18 US US17/127,738 patent/US20210113688A1/en not_active Abandoned
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2021
- 2021-02-02 US US17/165,724 patent/US20210162044A1/en not_active Abandoned
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2022
- 2022-12-02 US US18/061,227 patent/US20230321231A1/en active Pending
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2024
- 2024-12-16 US US18/983,037 patent/US20250161445A1/en active Pending
- 2024-12-16 US US18/983,034 patent/US20250161444A1/en active Pending
- 2024-12-16 US US18/983,030 patent/US12551554B2/en active Active
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