MA32628B1 - Agents antifongiques - Google Patents
Agents antifongiquesInfo
- Publication number
- MA32628B1 MA32628B1 MA33691A MA33691A MA32628B1 MA 32628 B1 MA32628 B1 MA 32628B1 MA 33691 A MA33691 A MA 33691A MA 33691 A MA33691 A MA 33691A MA 32628 B1 MA32628 B1 MA 32628B1
- Authority
- MA
- Morocco
- Prior art keywords
- compounds
- hydrates
- formulations
- salts
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Agronomy & Crop Science (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La présente invention concerne des dérivés inédits de l'enfumafungine, ainsi que leurs sels, hydrates et promédicaments pharmaceutiquement acceptables. L'invention concerne également des compositions contenant lesdits composés, des procédés de préparation desdits composés et des procédés d'utilisation desdits composés en tant qu'agents antifongiques et/ou qu'inhibiteurs de la (1,3)-²-d-glucan synthase. Les composés décrits, leurs sels, hydrates et promédicaments pharmaceutiquement acceptables, ainsi que les compositions comprenant lesdits composés, sels, hydrates et promédicaments se révèlent utiles dans le cadre du traitement et/ou de la prévention des infections fongiques et des maladies et affections associées.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13610608P | 2008-08-12 | 2008-08-12 | |
PCT/US2009/004557 WO2010019203A1 (fr) | 2008-08-12 | 2009-08-07 | Agents antifongiques |
Publications (1)
Publication Number | Publication Date |
---|---|
MA32628B1 true MA32628B1 (fr) | 2011-09-01 |
Family
ID=41669132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA33691A MA32628B1 (fr) | 2008-08-12 | 2011-03-11 | Agents antifongiques |
Country Status (31)
Country | Link |
---|---|
EP (1) | EP2326172B1 (fr) |
KR (1) | KR101686075B1 (fr) |
AR (1) | AR073037A1 (fr) |
BR (1) | BRPI0912074B1 (fr) |
CL (1) | CL2011000292A1 (fr) |
CO (1) | CO6351686A2 (fr) |
CR (1) | CR20110075A (fr) |
DK (1) | DK2326172T3 (fr) |
DO (1) | DOP2011000053A (fr) |
EA (1) | EA018337B1 (fr) |
ES (1) | ES2526652T3 (fr) |
GT (1) | GT201100039A (fr) |
HK (1) | HK1158017A1 (fr) |
HN (1) | HN2011000404A (fr) |
HR (1) | HRP20150009T1 (fr) |
IL (2) | IL210975A (fr) |
MA (1) | MA32628B1 (fr) |
MX (1) | MX2011001656A (fr) |
MY (1) | MY156955A (fr) |
NI (1) | NI201100035A (fr) |
NZ (1) | NZ590914A (fr) |
PE (1) | PE20110676A1 (fr) |
PL (1) | PL2326172T3 (fr) |
PT (1) | PT2326172E (fr) |
RS (1) | RS53731B1 (fr) |
SI (1) | SI2326172T1 (fr) |
SV (1) | SV2011003839A (fr) |
TW (1) | TWI439458B (fr) |
UA (1) | UA105639C2 (fr) |
WO (1) | WO2010019203A1 (fr) |
ZA (1) | ZA201100788B (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS63234B1 (sr) | 2015-01-19 | 2022-06-30 | Scynexis Inc | Nove soli i polimorfi scy-078 |
US11110102B2 (en) * | 2017-04-10 | 2021-09-07 | Scynexis, Inc. | Antifungal agents used in combination |
AU2018309718A1 (en) * | 2017-08-04 | 2020-02-27 | Scynexis, Inc. | Antifungal agents with enhanced activity in acidic pH |
EA202192107A1 (ru) * | 2019-01-30 | 2021-10-21 | Сайнексис, Инк. | Тритерпеноидные фунгициды для лечения грибковых костно-суставных инфекций |
EA202193146A1 (ru) * | 2019-05-16 | 2022-02-11 | Сайнексис, Инк. | Противогрибковые агенты для деколонизации candida auris |
US20230218652A1 (en) | 2020-05-29 | 2023-07-13 | Centre National De La Recherche Scientifique | Antifungal prodrugs |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5756472A (en) | 1996-01-31 | 1998-05-26 | Merck & Co., Inc. | Antifungal agent obtained from hormonema |
EP0877618B1 (fr) * | 1996-01-31 | 2003-01-02 | Merck & Co., Inc. | Agent antifongique |
EP1497281A4 (fr) * | 2002-04-17 | 2005-11-02 | Ranbaxy Lab Ltd | Derives azole utilises en tant qu'agents antifongiques |
DK2007396T3 (da) | 2006-04-03 | 2013-03-18 | Merck Sharp & Dohme | Enfumafungin-derivat som antimykotika |
-
2009
- 2009-08-07 PL PL09806944T patent/PL2326172T3/pl unknown
- 2009-08-07 RS RS20150006A patent/RS53731B1/en unknown
- 2009-08-07 BR BRPI0912074-2A patent/BRPI0912074B1/pt active IP Right Grant
- 2009-08-07 ES ES09806944.6T patent/ES2526652T3/es active Active
- 2009-08-07 SI SI200931102T patent/SI2326172T1/sl unknown
- 2009-08-07 PE PE2011000156A patent/PE20110676A1/es active IP Right Grant
- 2009-08-07 KR KR1020117005837A patent/KR101686075B1/ko active IP Right Grant
- 2009-08-07 UA UAA201102860A patent/UA105639C2/uk unknown
- 2009-08-07 MX MX2011001656A patent/MX2011001656A/es active IP Right Grant
- 2009-08-07 EA EA201100350A patent/EA018337B1/ru unknown
- 2009-08-07 NZ NZ590914A patent/NZ590914A/en unknown
- 2009-08-07 DK DK09806944.6T patent/DK2326172T3/da active
- 2009-08-07 PT PT98069446T patent/PT2326172E/pt unknown
- 2009-08-07 EP EP09806944.6A patent/EP2326172B1/fr active Active
- 2009-08-07 MY MYPI2011000483A patent/MY156955A/en unknown
- 2009-08-07 WO PCT/US2009/004557 patent/WO2010019203A1/fr active Application Filing
- 2009-08-10 TW TW098126822A patent/TWI439458B/zh active
- 2009-08-12 AR ARP090103123A patent/AR073037A1/es active IP Right Grant
-
2011
- 2011-01-31 IL IL210975A patent/IL210975A/en active IP Right Grant
- 2011-01-31 ZA ZA2011/00788A patent/ZA201100788B/en unknown
- 2011-02-08 CR CR20110075A patent/CR20110075A/es unknown
- 2011-02-10 NI NI201100035A patent/NI201100035A/es unknown
- 2011-02-11 HN HN2011000404A patent/HN2011000404A/es unknown
- 2011-02-11 CL CL2011000292A patent/CL2011000292A1/es unknown
- 2011-02-11 CO CO11016262A patent/CO6351686A2/es active IP Right Grant
- 2011-02-11 SV SV2011003839A patent/SV2011003839A/es active IP Right Grant
- 2011-02-11 DO DO2011000053A patent/DOP2011000053A/es unknown
- 2011-02-11 GT GT201100039A patent/GT201100039A/es unknown
- 2011-03-11 MA MA33691A patent/MA32628B1/fr unknown
- 2011-11-23 HK HK11112674.5A patent/HK1158017A1/xx unknown
-
2015
- 2015-01-07 HR HRP20150009AT patent/HRP20150009T1/hr unknown
- 2015-10-12 IL IL242031A patent/IL242031A0/en unknown
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