MA32167B1 - Dérivés d'imidazo[1,2-b]pyridazine pour le traitement de maladies médiées par la tyrosine kinase c-met - Google Patents

Dérivés d'imidazo[1,2-b]pyridazine pour le traitement de maladies médiées par la tyrosine kinase c-met

Info

Publication number
MA32167B1
MA32167B1 MA33198A MA33198A MA32167B1 MA 32167 B1 MA32167 B1 MA 32167B1 MA 33198 A MA33198 A MA 33198A MA 33198 A MA33198 A MA 33198A MA 32167 B1 MA32167 B1 MA 32167B1
Authority
MA
Morocco
Prior art keywords
treatment
tyrosine kinase
imidazo
mediated diseases
kinase mediated
Prior art date
Application number
MA33198A
Other languages
Arabic (ar)
English (en)
Inventor
Pascal Furet
Clive Mccarthy
Joseph Schoepfer
Carsten Spanka
Melanie Stang
Frédéric Stauffer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39672115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32167(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA32167B1 publication Critical patent/MA32167B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La présente invention concerne des composés de formule (i) et des sels de ceux-ci, formule (i), dans lesquels les substituants sont comme défini dans la spécification, l'application d'un composé de formule (i) dans un procédé pour le traitement du corps humain ou animal, en particulier en ce qui concerne une maladie médiée par la tyrosine kinase c-met; l'utilisation d'un composé de formule (i) pour fabriquer un médicament pour le traitement de telles maladies; des compositions pharmaceutiques comprenant un composé de formule (i), facultativement en présence d'un partenaire de combinaison; des procédés pour la préparation d'un composé de formule (i).
MA33198A 2008-02-28 2010-09-24 Dérivés d'imidazo[1,2-b]pyridazine pour le traitement de maladies médiées par la tyrosine kinase c-met MA32167B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08152068 2008-02-28
PCT/EP2009/052302 WO2009106577A1 (fr) 2008-02-28 2009-02-26 Dérivés d’imidazo[1,2-b]pyridazine pour le traitement de maladies médiées par la tyrosine kinase c-met

Publications (1)

Publication Number Publication Date
MA32167B1 true MA32167B1 (fr) 2011-03-01

Family

ID=39672115

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33198A MA32167B1 (fr) 2008-02-28 2010-09-24 Dérivés d'imidazo[1,2-b]pyridazine pour le traitement de maladies médiées par la tyrosine kinase c-met

Country Status (25)

Country Link
US (1) US8822468B2 (fr)
EP (1) EP2265614A1 (fr)
JP (1) JP5576802B2 (fr)
KR (1) KR20100128305A (fr)
CN (1) CN102015716B (fr)
AR (1) AR070487A1 (fr)
AU (1) AU2009218459A1 (fr)
BR (1) BRPI0908504A2 (fr)
CA (1) CA2717034A1 (fr)
CL (1) CL2009000443A1 (fr)
CO (1) CO6300957A2 (fr)
CR (1) CR11620A (fr)
DO (1) DOP2010000263A (fr)
EA (1) EA201001365A1 (fr)
EC (1) ECSP10010427A (fr)
IL (1) IL207434A0 (fr)
MA (1) MA32167B1 (fr)
MX (1) MX2010009414A (fr)
NI (1) NI201000145A (fr)
PE (1) PE20091468A1 (fr)
SM (1) SMAP201000112A (fr)
TW (1) TW200940545A (fr)
UY (1) UY31676A1 (fr)
WO (1) WO2009106577A1 (fr)
ZA (1) ZA201005602B (fr)

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CN103122000B (zh) * 2012-09-03 2013-12-25 中美冠科生物技术（太仓）有限公司 用作抗肿瘤药物的高选择性的c-Met激酶抑制剂
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EP3512852B1 (fr) * 2016-09-16 2024-06-26 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Inhibiteurs de traf6
WO2018138050A1 (fr) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Dérivés hétérocycliques bicycliques condensés utilisés comme pesticides
US11584744B2 (en) * 2017-06-23 2023-02-21 University Of Washington Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them
US20230059009A1 (en) * 2019-12-18 2023-02-23 The Regents Of The University Of California Inhibitors of lin28 and methods of use thereof

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Also Published As

Publication number Publication date
US20090264406A1 (en) 2009-10-22
JP2011513279A (ja) 2011-04-28
CR11620A (es) 2010-10-08
WO2009106577A1 (fr) 2009-09-03
ECSP10010427A (es) 2010-09-30
ZA201005602B (en) 2011-04-28
TW200940545A (en) 2009-10-01
BRPI0908504A2 (pt) 2015-08-11
CO6300957A2 (es) 2011-07-21
UY31676A1 (es) 2009-09-30
CN102015716B (zh) 2014-09-17
SMAP201000112A (it) 2010-11-12
CA2717034A1 (fr) 2009-09-03
NI201000145A (es) 2011-03-02
CL2009000443A1 (es) 2010-09-10
AR070487A1 (es) 2010-04-07
JP5576802B2 (ja) 2014-08-20
KR20100128305A (ko) 2010-12-07
EA201001365A1 (ru) 2011-04-29
MX2010009414A (es) 2010-09-24
DOP2010000263A (es) 2010-09-30
IL207434A0 (en) 2010-12-30
AU2009218459A1 (en) 2009-09-03
US8822468B2 (en) 2014-09-02
EP2265614A1 (fr) 2010-12-29
PE20091468A1 (es) 2009-10-22
CN102015716A (zh) 2011-04-13

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