MA28937B1 - Composes et compositions servant d'inhibiteurs d'activite de recepteur cannabinoide de type 1 - Google Patents

Composes et compositions servant d'inhibiteurs d'activite de recepteur cannabinoide de type 1

Info

Publication number
MA28937B1
MA28937B1 MA29834A MA29834A MA28937B1 MA 28937 B1 MA28937 B1 MA 28937B1 MA 29834 A MA29834 A MA 29834A MA 29834 A MA29834 A MA 29834A MA 28937 B1 MA28937 B1 MA 28937B1
Authority
MA
Morocco
Prior art keywords
inhibitors
compositions
compounds
receptor activity
cannabinoid receptor
Prior art date
Application number
MA29834A
Other languages
English (en)
Inventor
Hong Liu
Xiaohui He
Ha-Soon Choi
Kunyong Yang
David Woodmansee
Zhicheng Wang
David Archer Ellis
Baogen Wu
Yun He
Truc Ngoc Nguyen
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of MA28937B1 publication Critical patent/MA28937B1/fr

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    • C07—ORGANIC CHEMISTRY
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C07D471/04—Ortho-condensed systems
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
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    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
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    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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    • C07D498/04—Ortho-condensed systems

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  • Diabetes (AREA)
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  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
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  • Urology & Nephrology (AREA)
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MA29834A 2004-10-26 2007-04-18 Composes et compositions servant d'inhibiteurs d'activite de recepteur cannabinoide de type 1 MA28937B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62250804P 2004-10-26 2004-10-26
US67267005P 2005-04-18 2005-04-18

Publications (1)

Publication Number Publication Date
MA28937B1 true MA28937B1 (fr) 2007-10-01

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Application Number Title Priority Date Filing Date
MA29834A MA28937B1 (fr) 2004-10-26 2007-04-18 Composes et compositions servant d'inhibiteurs d'activite de recepteur cannabinoide de type 1

Country Status (19)

Country Link
US (2) US8158634B2 (fr)
EP (1) EP1807429A4 (fr)
JP (2) JP2008518016A (fr)
KR (1) KR100919524B1 (fr)
CN (2) CN102241680A (fr)
AR (1) AR051596A1 (fr)
AU (2) AU2005299421B2 (fr)
BR (1) BRPI0517015A (fr)
CA (2) CA2581225C (fr)
EC (1) ECSP077421A (fr)
IL (1) IL182527A0 (fr)
MA (1) MA28937B1 (fr)
MX (1) MX2007004936A (fr)
NO (1) NO20072352L (fr)
PE (1) PE20060599A1 (fr)
RU (1) RU2431635C2 (fr)
TN (1) TNSN07161A1 (fr)
TW (1) TW200630096A (fr)
WO (1) WO2006047516A2 (fr)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516572A (ja) 2003-01-14 2006-07-06 アリーナ ファーマシューティカルズ， インコーポレイテッド 代謝モジュレーターとしての１，２，３−トリ置換アリール誘導体および１，２，３−トリ置換ヘテロアリール誘導体ならびにこれらの誘導体に関連する糖尿病および高血糖のような障害の予防および処置
JP4920410B2 (ja) 2003-07-14 2012-04-18 アリーナ ファーマシューティカルズ， インコーポレイテッド 代謝モジュレーターとしての縮合アリールおよびヘテロアリール誘導体ならびに代謝に関連する障害の予防および治療
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