TW200630096A - Compounds and compositions as inhibitors of cannabinoid receptor 1 activity - Google Patents
Compounds and compositions as inhibitors of cannabinoid receptor 1 activityInfo
- Publication number
- TW200630096A TW200630096A TW094137369A TW94137369A TW200630096A TW 200630096 A TW200630096 A TW 200630096A TW 094137369 A TW094137369 A TW 094137369A TW 94137369 A TW94137369 A TW 94137369A TW 200630096 A TW200630096 A TW 200630096A
- Authority
- TW
- Taiwan
- Prior art keywords
- compounds
- activity
- cannabinoid receptor
- compositions
- inhibitors
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
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- C07D473/28—Oxygen atom
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-
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- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
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- C07D498/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62250804P | 2004-10-26 | 2004-10-26 | |
US67267005P | 2005-04-18 | 2005-04-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200630096A true TW200630096A (en) | 2006-09-01 |
Family
ID=36228382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094137369A TW200630096A (en) | 2004-10-26 | 2005-10-25 | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity |
Country Status (19)
Country | Link |
---|---|
US (2) | US8158634B2 (zh) |
EP (1) | EP1807429A4 (zh) |
JP (2) | JP2008518016A (zh) |
KR (1) | KR100919524B1 (zh) |
CN (2) | CN102241680A (zh) |
AR (1) | AR051596A1 (zh) |
AU (2) | AU2005299421B2 (zh) |
BR (1) | BRPI0517015A (zh) |
CA (2) | CA2730374A1 (zh) |
EC (1) | ECSP077421A (zh) |
IL (1) | IL182527A0 (zh) |
MA (1) | MA28937B1 (zh) |
MX (1) | MX2007004936A (zh) |
NO (1) | NO20072352L (zh) |
PE (1) | PE20060599A1 (zh) |
RU (1) | RU2431635C2 (zh) |
TN (1) | TNSN07161A1 (zh) |
TW (1) | TW200630096A (zh) |
WO (1) | WO2006047516A2 (zh) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GEP20084540B (en) | 2003-01-14 | 2008-11-25 | Arena Pharm Inc | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
TWI335328B (en) | 2003-07-14 | 2011-01-01 | Arena Pharm Inc | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related hereto |
WO2005074643A2 (en) * | 2004-01-30 | 2005-08-18 | Smithkline Beecham Corporation | Benzamide compounds useful as rock inhibitors |
AR051596A1 (es) * | 2004-10-26 | 2007-01-24 | Irm Llc | Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios |
GB0506147D0 (en) * | 2005-03-24 | 2005-05-04 | Merck Sharp & Dohme | Therapeutic agents |
AU2006244027A1 (en) * | 2005-05-11 | 2006-11-16 | Merck Sharp & Dohme Limited | 2,3-substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilloid-1 receptor (VR1) |
WO2007000655A2 (en) * | 2005-06-28 | 2007-01-04 | Orchid Research Laboratories Limited | Novel pyrazolopyrimidinone derivatives |
WO2007056124A2 (en) | 2005-11-04 | 2007-05-18 | Hydra Biosciences, Inc. | Compounds for modulating trpv3 function |
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- 2005-10-26 CN CN2011101210450A patent/CN102241680A/zh active Pending
- 2005-10-26 CA CA2730374A patent/CA2730374A1/en not_active Abandoned
- 2005-10-26 WO PCT/US2005/038361 patent/WO2006047516A2/en active Application Filing
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- 2005-10-26 EP EP05813001A patent/EP1807429A4/en not_active Withdrawn
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- 2005-10-26 MX MX2007004936A patent/MX2007004936A/es not_active Application Discontinuation
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AU2009251216A1 (en) | 2010-01-28 |
EP1807429A4 (en) | 2010-03-24 |
NO20072352L (no) | 2007-05-31 |
KR100919524B1 (ko) | 2009-10-01 |
RU2007119449A (ru) | 2008-12-10 |
BRPI0517015A (pt) | 2008-09-30 |
US20120225869A1 (en) | 2012-09-06 |
MA28937B1 (fr) | 2007-10-01 |
US20090247517A1 (en) | 2009-10-01 |
US8158634B2 (en) | 2012-04-17 |
CA2581225C (en) | 2011-10-25 |
CN102241680A (zh) | 2011-11-16 |
JP2008518016A (ja) | 2008-05-29 |
MX2007004936A (es) | 2007-06-25 |
WO2006047516A2 (en) | 2006-05-04 |
CA2730374A1 (en) | 2006-05-04 |
CA2581225A1 (en) | 2006-05-04 |
AU2005299421B2 (en) | 2010-01-28 |
EP1807429A2 (en) | 2007-07-18 |
PE20060599A1 (es) | 2006-08-22 |
CN101048408B (zh) | 2011-07-06 |
RU2431635C2 (ru) | 2011-10-20 |
WO2006047516A3 (en) | 2006-10-12 |
AR051596A1 (es) | 2007-01-24 |
JP2011190281A (ja) | 2011-09-29 |
IL182527A0 (en) | 2007-09-20 |
TNSN07161A1 (en) | 2008-11-21 |
AU2005299421A1 (en) | 2006-05-04 |
CN101048408A (zh) | 2007-10-03 |
KR20070057980A (ko) | 2007-06-07 |
ECSP077421A (es) | 2007-05-30 |
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