ECSP077421A - Compuestos y composiciones como inhibidores de la actividad del receptor canabinoide 1 - Google Patents

Compuestos y composiciones como inhibidores de la actividad del receptor canabinoide 1

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Publication number
ECSP077421A
ECSP077421A EC2007007421A ECSP077421A ECSP077421A EC SP077421 A ECSP077421 A EC SP077421A EC 2007007421 A EC2007007421 A EC 2007007421A EC SP077421 A ECSP077421 A EC SP077421A EC SP077421 A ECSP077421 A EC SP077421A
Authority
EC
Ecuador
Prior art keywords
compounds
activity
canabinoid
compositions
inhibitors
Prior art date
Application number
EC2007007421A
Other languages
English (en)
Inventor
Hong Liu
Xiaohui He
Ha-Soon Choi
Kunyong Yang
David Woodmansee
Zhicheng Wang
David Archer Ellis
Baogen Wu
Yun He
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of ECSP077421A publication Critical patent/ECSP077421A/es

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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
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    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
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Abstract

La invención proporciona compuestos, composiciones farmacéuticas que comprenden tales compuestos, y métodos para utilizar tales compuestos con el fin de tratar o prevenir enfermedades o trastornos asociados con la actividad del Receptor Canabinoide 1 (CB1).
EC2007007421A 2004-10-26 2007-04-26 Compuestos y composiciones como inhibidores de la actividad del receptor canabinoide 1 ECSP077421A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62250804P 2004-10-26 2004-10-26
US67267005P 2005-04-18 2005-04-18

Publications (1)

Publication Number Publication Date
ECSP077421A true ECSP077421A (es) 2007-05-30

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ID=36228382

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Application Number Title Priority Date Filing Date
EC2007007421A ECSP077421A (es) 2004-10-26 2007-04-26 Compuestos y composiciones como inhibidores de la actividad del receptor canabinoide 1

Country Status (19)

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US (2) US8158634B2 (es)
EP (1) EP1807429A4 (es)
JP (2) JP2008518016A (es)
KR (1) KR100919524B1 (es)
CN (2) CN101048408B (es)
AR (1) AR051596A1 (es)
AU (2) AU2005299421B2 (es)
BR (1) BRPI0517015A (es)
CA (2) CA2581225C (es)
EC (1) ECSP077421A (es)
IL (1) IL182527A0 (es)
MA (1) MA28937B1 (es)
MX (1) MX2007004936A (es)
NO (1) NO20072352L (es)
PE (1) PE20060599A1 (es)
RU (1) RU2431635C2 (es)
TN (1) TNSN07161A1 (es)
TW (1) TW200630096A (es)
WO (1) WO2006047516A2 (es)

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WO2004065380A1 (en) 2003-01-14 2004-08-05 Arena Pharmaceuticals Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
JP4920410B2 (ja) 2003-07-14 2012-04-18 アリーナ ファーマシューティカルズ， インコーポレイテッド 代謝モジュレーターとしての縮合アリールおよびヘテロアリール誘導体ならびに代謝に関連する障害の予防および治療
JP2007519754A (ja) * 2004-01-30 2007-07-19 スミスクライン ビーチャム コーポレーション 化合物
AR051596A1 (es) * 2004-10-26 2007-01-24 Irm Llc Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios
GB0506147D0 (en) * 2005-03-24 2005-05-04 Merck Sharp & Dohme Therapeutic agents
JP2009536608A (ja) * 2005-05-11 2009-10-15 メルク シャープ エンド ドーム リミテッド バニロイド−１受容体（ｖｒ１）の機能を調節する２，３−置換縮合二環式ピリミジン４−（３ｈ）−オン
WO2007000655A2 (en) * 2005-06-28 2007-01-04 Orchid Research Laboratories Limited Novel pyrazolopyrimidinone derivatives
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