IS2991B - Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs - Google Patents

Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs

Info

Publication number
IS2991B
IS2991B IS7276A IS7276A IS2991B IS 2991 B IS2991 B IS 2991B IS 7276 A IS7276 A IS 7276A IS 7276 A IS7276 A IS 7276A IS 2991 B IS2991 B IS 2991B
Authority
IS
Iceland
Prior art keywords
receptor antagonist
nanoparticle composition
tachykinin receptor
pharmaceutical nanoparticle
pharmaceutical
Prior art date
Application number
IS7276A
Other languages
English (en)
Other versions
IS7276A (is
Inventor
H. Bosch William
Liversidge Elaine
D. Shelukar Suhas
C. Thompson Karen
Original Assignee
Merck Sharp & Dohme Corp., (A New Jersey Corporation)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23331619&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS2991(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme Corp., (A New Jersey Corporation) filed Critical Merck Sharp & Dohme Corp., (A New Jersey Corporation)
Publication of IS7276A publication Critical patent/IS7276A/is
Publication of IS2991B publication Critical patent/IS2991B/is

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS7276A 2001-12-10 2004-05-21 Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs IS2991B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34004001P 2001-12-10 2001-12-10
PCT/US2002/041655 WO2003049718A1 (en) 2001-12-10 2002-12-09 Pharmaceutical nanoparticulate composition of a tachykinin receptor antagonist

Publications (2)

Publication Number Publication Date
IS7276A IS7276A (is) 2004-05-21
IS2991B true IS2991B (is) 2017-12-15

Family

ID=23331619

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7276A IS2991B (is) 2001-12-10 2004-05-21 Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs

Country Status (38)

Country Link
US (1) US8258132B2 (is)
EP (1) EP1455756B2 (is)
JP (1) JP4532114B2 (is)
KR (1) KR20040063991A (is)
CN (1) CN100352443C (is)
AR (1) AR037713A1 (is)
AT (1) ATE400254T1 (is)
AU (1) AU2002360824B8 (is)
BR (1) BRPI0214786B8 (is)
CA (1) CA2469315C (is)
CO (1) CO5590887A2 (is)
CY (1) CY1108354T1 (is)
DE (1) DE60227556D1 (is)
DK (1) DK1455756T4 (is)
DO (1) DOP2002000542A (is)
EA (1) EA007332B1 (is)
EC (1) ECSP045144A (is)
ES (1) ES2307820T5 (is)
GE (1) GEP20063875B (is)
HR (1) HRP20040532B1 (is)
HU (1) HU230736B1 (is)
IL (3) IL162296A0 (is)
IS (1) IS2991B (is)
JO (1) JO3060B1 (is)
ME (1) ME00450B (is)
MX (1) MXPA04005563A (is)
MY (1) MY155911A (is)
NO (1) NO336943B1 (is)
NZ (1) NZ534009A (is)
PE (1) PE20030641A1 (is)
PL (1) PL211243B6 (is)
PT (1) PT1455756E (is)
RS (1) RS52280B (is)
SI (1) SI1455756T2 (is)
TW (1) TWI249403B (is)
UA (1) UA76810C2 (is)
WO (1) WO2003049718A1 (is)
ZA (1) ZA200404012B (is)

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Also Published As

Publication number Publication date
ES2307820T3 (es) 2008-12-01
ME00450B (me) 2011-10-10
TWI249403B (en) 2006-02-21
PL211243B6 (pl) 2023-01-23
PT1455756E (pt) 2008-10-16
DE60227556D1 (de) 2008-08-21
IS7276A (is) 2004-05-21
CY1108354T1 (el) 2012-05-23
CA2469315A1 (en) 2003-06-19
RS50404A (sr) 2007-04-10
SI1455756T2 (sl) 2016-01-29
EA007332B1 (ru) 2006-08-25
ECSP045144A (es) 2004-07-23
EA200400794A1 (ru) 2004-10-28
DK1455756T4 (en) 2016-01-04
AU2002360824A1 (en) 2003-06-23
IL201658A0 (en) 2011-08-01
HU230736B1 (hu) 2018-01-29
DK1455756T3 (da) 2008-11-17
WO2003049718A1 (en) 2003-06-19
HUP0402596A2 (hu) 2005-03-29
IL162296A0 (en) 2005-11-20
EP1455756B2 (en) 2015-09-23
BRPI0214786B1 (pt) 2018-11-27
AU2002360824B8 (en) 2008-05-22
BR0214786A (pt) 2004-11-09
PL211243B1 (pl) 2012-04-30
KR20040063991A (ko) 2004-07-15
CA2469315C (en) 2008-12-02
HK1078017A1 (zh) 2006-03-03
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TW200301125A (en) 2003-07-01
PE20030641A1 (es) 2003-07-23
US20040214746A1 (en) 2004-10-28
EP1455756B1 (en) 2008-07-09
SI1455756T1 (sl) 2008-12-31
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NO20042905L (no) 2004-09-10
AR037713A1 (es) 2004-12-01
EP1455756A1 (en) 2004-09-15
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CN100352443C (zh) 2007-12-05
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AU2002360824B2 (en) 2008-05-08
ATE400254T1 (de) 2008-07-15
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RS52280B (sr) 2012-10-31
DOP2002000542A (es) 2003-07-15
UA76810C2 (uk) 2006-09-15
ZA200404012B (en) 2005-10-26
BRPI0214786B8 (pt) 2021-05-25
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JO3060B1 (ar) 2017-03-15
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