MA28045A1 - Solvat acetonique du dimethoxy docetaxel et son procede de preparation - Google Patents

Solvat acetonique du dimethoxy docetaxel et son procede de preparation

Info

Publication number
MA28045A1
MA28045A1 MA28881A MA28881A MA28045A1 MA 28045 A1 MA28045 A1 MA 28045A1 MA 28881 A MA28881 A MA 28881A MA 28881 A MA28881 A MA 28881A MA 28045 A1 MA28045 A1 MA 28045A1
Authority
MA
Morocco
Prior art keywords
acetonic
solvat
preparing
same
dimethoxy
Prior art date
Application number
MA28881A
Other languages
English (en)
French (fr)
Inventor
Eric Didier
Marc-Antoine Perrin
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34224354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA28045(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of MA28045A1 publication Critical patent/MA28045A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
MA28881A 2003-09-19 2006-03-17 Solvat acetonique du dimethoxy docetaxel et son procede de preparation MA28045A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0311016A FR2859996B1 (fr) 2003-09-19 2003-09-19 Solvat acetonique du dimethoxy docetaxel et son procede de preparation

Publications (1)

Publication Number Publication Date
MA28045A1 true MA28045A1 (fr) 2006-07-03

Family

ID=34224354

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28881A MA28045A1 (fr) 2003-09-19 2006-03-17 Solvat acetonique du dimethoxy docetaxel et son procede de preparation

Country Status (37)

Country Link
US (1) US7241907B2 (en:Method)
EP (1) EP1667986B1 (en:Method)
JP (1) JP5010279B2 (en:Method)
KR (1) KR101123588B1 (en:Method)
CN (1) CN100429207C (en:Method)
AR (1) AR045667A1 (en:Method)
AU (1) AU2004274212B2 (en:Method)
BE (1) BE2013C036I2 (en:Method)
BR (1) BRPI0414492A8 (en:Method)
CA (1) CA2539309A1 (en:Method)
CR (1) CR8292A (en:Method)
CY (2) CY1114575T1 (en:Method)
DK (1) DK1667986T3 (en:Method)
ES (1) ES2403149T4 (en:Method)
FR (2) FR2859996B1 (en:Method)
HR (1) HRP20130322T1 (en:Method)
HU (1) HUS1300025I1 (en:Method)
IL (1) IL174240A (en:Method)
LU (1) LU92172I2 (en:Method)
MA (1) MA28045A1 (en:Method)
ME (2) MEP11708A (en:Method)
MX (1) MXPA06002639A (en:Method)
MY (1) MY136668A (en:Method)
NO (2) NO335997B1 (en:Method)
NZ (1) NZ545835A (en:Method)
PA (1) PA8612401A1 (en:Method)
PE (1) PE20050870A1 (en:Method)
PL (1) PL1667986T3 (en:Method)
PT (1) PT1667986E (en:Method)
RS (2) RS20060189A (en:Method)
RU (1) RU2342373C2 (en:Method)
SI (1) SI1667986T1 (en:Method)
TN (1) TNSN06086A1 (en:Method)
TW (1) TWI382022B (en:Method)
UA (1) UA87115C2 (en:Method)
WO (1) WO2005028462A1 (en:Method)
ZA (1) ZA200602255B (en:Method)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2001874A4 (en) * 2006-03-21 2010-04-07 Reddys Lab Ltd Dr DOCETAXEL POLYMORPH AND CORRESPONDING METHODS
US7855591B2 (en) * 2006-06-07 2010-12-21 Atmel Corporation Method and system for providing a charge pump very low voltage applications
US7652522B2 (en) * 2006-09-05 2010-01-26 Atmel Corporation High efficiency low cost bi-directional charge pump circuit for very low voltage applications
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
AU2013205442B2 (en) * 2008-01-17 2016-05-12 Aventis Pharma S.A. Crystalline forms of dimethoxy docetaxel and methods for preparing same
EP2331140B1 (en) 2008-08-11 2018-07-04 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
FR2945211A1 (fr) * 2009-05-06 2010-11-12 Sanofi Aventis Combinaison antitumorale comprenant la cabazitaxel et la capecitabine
CA2708489A1 (en) * 2009-10-29 2011-04-29 Aventis Pharma S.A. Use of cabazitaxel and a prednisone or a prednisolone in the treatment of prostate cancer
WO2011051894A1 (en) 2009-10-29 2011-05-05 Aventis Pharma S.A. Novel antitumoral use of cabazitaxel
AU2015200149B2 (en) * 2009-10-29 2016-12-01 Aventis Pharma S.A. Novel antitumoral use of cabazitaxel
WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
US20130331443A1 (en) 2010-12-22 2013-12-12 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
CN103764637A (zh) * 2011-04-12 2014-04-30 普拉斯化学品有限公司 卡巴他赛的固态形式及其制备方法
WO2013024495A1 (en) * 2011-08-18 2013-02-21 Dr. Reddys Laboratories Limited Pharmaceutical formulations of cabazitaxel
TWI526437B (zh) * 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
US8722900B2 (en) 2011-10-31 2014-05-13 Scinopharm Taiwan, Ltd. Process for cabazitaxel, and intermediates thereof
CN103874692A (zh) 2011-11-01 2014-06-18 费森尤斯卡比肿瘤学有限公司 卡巴他赛的无定形形式和用于其制备的方法
ES2716799T3 (es) 2011-11-28 2019-06-17 Fresenius Kabi Oncology Ltd Forma cristalina de cabazitaxel y proceso para la preparación de la misma
JP6025861B2 (ja) 2011-12-13 2016-11-16 アベンティス・ファーマ・ソシエテ・アノニム カバジタキセルの結晶形およびこれを調製するための方法
WO2013111157A1 (en) * 2012-01-03 2013-08-01 Shilpa Medicare Limited Process for preparing amorphous cabazitaxel
SG11201404712UA (en) * 2012-02-10 2014-09-26 Aventis Pharma Sa New pediatric uses of cabazitaxel
US9394266B2 (en) 2012-03-08 2016-07-19 IVAX International GmbH Solid state forms of cabazitaxel and processes for preparation thereof
CN102675257B (zh) * 2012-05-10 2014-07-02 上海金和生物技术有限公司 一种卡巴他赛晶体及其制备方法
CN102746258B (zh) * 2012-07-25 2015-02-04 重庆泰濠制药有限公司 卡巴他赛的结晶形式及其制备方法
EP2880021A4 (en) 2012-07-31 2015-06-17 Yung Shin Pharm Ind Co Ltd AMORPHIC CABACITAXEL
WO2014028704A1 (en) 2012-08-15 2014-02-20 Yung Shin Pharm. Ind. Co., Ltd. Stable pharmaceutical formulation of cabazitaxel
CN103664836B (zh) * 2012-09-20 2016-04-20 齐鲁制药有限公司 7β,10β-二甲氧基多西紫杉醇氘代丙酮合物的晶型A及其制备方法
US20140094432A1 (en) 2012-10-02 2014-04-03 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
CN103804323A (zh) * 2012-11-14 2014-05-21 上海希迈医药科技有限公司 一种卡巴他赛溶剂化物及其制备方法和应用
CN103058960B (zh) * 2012-12-12 2014-12-10 江苏奥赛康药业股份有限公司 卡巴他赛多晶型形式及其制备方法
EP2743264A1 (en) 2012-12-13 2014-06-18 INDENA S.p.A. New crystalline form of cabazitaxel, process for the preparation and pharmaceutical compositions thereof
CN103910698B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛丙酮合物及其结晶
CN103910696B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛异丙醚合物及其结晶
EP2777691A1 (en) 2013-03-14 2014-09-17 Pharmachemie B.V. Taxoid - Purification of Liquid Excipients
EP2815749A1 (en) 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
WO2015000165A1 (zh) * 2013-07-04 2015-01-08 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
CN104277014A (zh) * 2013-07-04 2015-01-14 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
EP2865675A1 (en) 2013-10-23 2015-04-29 INDENA S.p.A. A crystalline anhydrous form of Cabazitaxel, process for the preparation and pharmaceutical compositions thereof
EP2865674A1 (en) 2013-10-23 2015-04-29 INDENA S.p.A. Crystalline solvate forms of Cabazitaxel
CN103601704B (zh) * 2013-11-22 2015-05-06 石家庄智恒医药科技有限公司 无定形卡巴他赛的制备
ES2904505T3 (es) 2015-01-12 2022-04-05 Emcure Pharmaceuticals Ltd Formulación líquida de cabazitaxel
PL3258931T3 (pl) * 2015-02-17 2020-12-28 Erasmus University Medical Center Rotterdam Zastosowanie kabazitakselu w leczeniu nowotworu złośliwego prostaty
EP3093014A1 (en) 2015-05-13 2016-11-16 Aventis Pharma S.A. Cabazitaxel and its use for treating cancer
US10188626B2 (en) 2015-11-03 2019-01-29 Cipla Limited Stabilized cabazitaxel formulations
CN116903624A (zh) 2016-11-29 2023-10-20 Ptc医疗Mp公司 墨蝶呤及其盐的多晶型物
CN110312721A (zh) 2016-11-29 2019-10-08 显莎制药公司 墨蝶呤的多晶型物
BR112020003865A8 (pt) 2017-09-01 2022-08-16 Censa Pharmaceuticals Inc Composições farmacêuticas compreendendo sepiapterina e seus usos
US11617752B2 (en) 2018-05-30 2023-04-04 Ptc Therapeutics Mp, Inc. Methods for increasing sepiapterin plasma exposure
BR112020024329A2 (pt) 2018-05-30 2021-02-23 Ptc Therapeutics Mp, Inc. composições e métodos para aumentar exposição de plasma de tetra-hidrobiopterin
WO2020249507A1 (en) 2019-06-11 2020-12-17 Indena S.P.A. Anhydrous crystalline form of cabazitaxel, a process for its preparation and pharmaceutical compositions containing it
EP3797834A1 (en) 2019-09-25 2021-03-31 Sanofi Mature IP Cabazitaxel in mcrpc patients previously treated with docetaxel and who failed a prior androgen signaling targeted inhibitor agent
EP3808345A1 (en) 2019-10-15 2021-04-21 Sanofi Mature IP Cabazitaxel in mcrpc patients previously treated with docetaxel and who failed a prior androgen signaling targeted inhibitor agent

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766635A (en) * 1991-06-28 1998-06-16 Rhone-Poulenc Rorer S.A. Process for preparing nanoparticles
FR2722191B1 (fr) * 1994-07-08 1996-08-23 Rhone Poulenc Rorer Sa Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle
DE4425978C1 (de) * 1994-07-22 1995-11-23 Karlsruhe Forschzent Verfahren zur Herstellung keramischer Mikrostrukturen
MA23823A1 (fr) * 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
FR2745814B1 (fr) * 1996-03-06 1998-04-03 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2771092B1 (fr) 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides
EP0982027A1 (en) * 1998-08-17 2000-03-01 Aventis Pharma S.A. Taxoid derivatives for treating abnormal cell proliferation of the brain
US6346543B1 (en) * 1998-08-17 2002-02-12 Aventis Pharma S.A. Use of a taxoid to treat abnormal cell proliferation in the brain
US6136989A (en) * 1998-12-30 2000-10-24 Phytogen Life Sciences, Incorporated Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material
US5969165A (en) * 1999-01-07 1999-10-19 508037 (Nb) Inc. Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column
IL144976A0 (en) * 1999-05-17 2002-06-30 Bristol Myers Squibb Co A process for the preparation of paclitaxel
EP1457492B1 (en) * 2001-11-29 2008-01-02 Daiichi Sankyo Company, Limited Crystals of taxane derivative and process for their production

Also Published As

Publication number Publication date
IL174240A0 (en) 2006-08-01
RS20060189A (en) 2008-06-05
RU2342373C2 (ru) 2008-12-27
NO2015013I1 (no) 2015-05-04
MXPA06002639A (es) 2006-06-05
PL1667986T3 (pl) 2013-06-28
JP2007505866A (ja) 2007-03-15
KR101123588B1 (ko) 2012-03-22
ES2403149T3 (es) 2013-05-14
FR2859996A1 (fr) 2005-03-25
LU92172I2 (fr) 2013-05-21
ES2403149T4 (es) 2013-06-24
BE2013C036I2 (en:Method) 2023-12-14
EP1667986A1 (fr) 2006-06-14
DK1667986T3 (da) 2013-05-06
ZA200602255B (en) 2007-07-25
SI1667986T1 (sl) 2013-05-31
WO2005028462A1 (fr) 2005-03-31
PE20050870A1 (es) 2005-11-21
CA2539309A1 (fr) 2005-03-31
CY1114575T1 (el) 2016-10-05
FR13C0037I1 (fr) 2013-09-08
CR8292A (es) 2008-10-15
MY136668A (en) 2008-11-28
HK1093340A1 (zh) 2007-03-02
UA87115C2 (ru) 2009-06-25
AU2004274212B2 (en) 2010-03-04
EP1667986B1 (fr) 2013-01-16
CN1849311A (zh) 2006-10-18
FR13C0037I2 (fr) 2015-11-20
AU2004274212A1 (en) 2005-03-31
TW200524891A (en) 2005-08-01
TWI382022B (zh) 2013-01-11
AR045667A1 (es) 2005-11-02
BRPI0414492A8 (pt) 2019-01-15
NO335997B1 (no) 2015-04-20
US7241907B2 (en) 2007-07-10
PT1667986E (pt) 2013-04-24
ME00054B (me) 2011-02-10
US20050065138A1 (en) 2005-03-24
KR20060072147A (ko) 2006-06-27
CY2013016I2 (el) 2018-01-10
BRPI0414492A (pt) 2006-11-14
HRP20130322T1 (en) 2013-07-31
IL174240A (en) 2010-12-30
RU2006113122A (ru) 2006-08-27
RS54614B1 (en) 2016-08-31
LU92172I9 (en:Method) 2019-01-03
HUS1300025I1 (hu) 2016-08-29
PA8612401A1 (es) 2005-08-04
NO20061714L (no) 2006-04-19
NO2015013I2 (no) 2015-04-22
NZ545835A (en) 2009-10-30
TNSN06086A1 (en) 2007-10-03
JP5010279B2 (ja) 2012-08-29
CN100429207C (zh) 2008-10-29
CY2013016I1 (el) 2018-01-10
MEP11708A (en) 2010-06-10
FR2859996B1 (fr) 2006-02-03

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