MA26867A1 - Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composés - Google Patents
Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composésInfo
- Publication number
- MA26867A1 MA26867A1 MA26735A MA26735A MA26867A1 MA 26867 A1 MA26867 A1 MA 26867A1 MA 26735 A MA26735 A MA 26735A MA 26735 A MA26735 A MA 26735A MA 26867 A1 MA26867 A1 MA 26867A1
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- dicarboxylates
- diabetes
- preparation
- vascular diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
DEPOSANT Société dite: WARNER-LAMBERTCOMPANY REVENDICATION DE PRIORITES US 25 Janvier 2000 60/177,823 "Ether-dicarboxylates de calcium, procédés pour leur préparation et traitement de maladies vasculaires et du diabète avec ces composés" Les produits de solvatation avec des alcools et l'eau du sel monocalcique d'acide 6-(5-carboxy-5-méthyi-hexyloxy)-2,2-diméthyl-hexanoïque sont cristallins et répondent à la formule (I), dans laquelle R1 représente H ou un groupe alkyle inférieur, et x est un nombre de 0 à 10, et sont utiles pour le traitement de la dyslipidémie.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17782300P | 2000-01-25 | 2000-01-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA26867A1 true MA26867A1 (fr) | 2004-12-20 |
Family
ID=22650106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA26735A MA26867A1 (fr) | 2000-01-25 | 2002-07-22 | Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composés |
Country Status (39)
Country | Link |
---|---|
EP (1) | EP1259474B1 (fr) |
JP (1) | JP4750995B2 (fr) |
KR (1) | KR20020073182A (fr) |
CN (1) | CN1395555A (fr) |
AP (1) | AP2002002587A0 (fr) |
AR (1) | AR029436A1 (fr) |
AT (1) | ATE431326T1 (fr) |
AU (1) | AU2214001A (fr) |
BG (1) | BG106851A (fr) |
BR (1) | BR0107763A (fr) |
CA (1) | CA2397960C (fr) |
CO (1) | CO5261537A1 (fr) |
CZ (1) | CZ20022474A3 (fr) |
DE (1) | DE60138686D1 (fr) |
DK (1) | DK1259474T3 (fr) |
DZ (1) | DZ3239A1 (fr) |
EA (1) | EA004862B1 (fr) |
EE (1) | EE200200404A (fr) |
ES (1) | ES2324281T3 (fr) |
GE (1) | GEP20053428B (fr) |
GT (1) | GT200100015A (fr) |
HN (1) | HN2001000011A (fr) |
HU (1) | HUP0204422A3 (fr) |
IL (1) | IL150541A0 (fr) |
IS (1) | IS6442A (fr) |
MA (1) | MA26867A1 (fr) |
MX (1) | MXPA02007223A (fr) |
NO (1) | NO20023526L (fr) |
NZ (1) | NZ519550A (fr) |
OA (1) | OA12166A (fr) |
PA (1) | PA8510601A1 (fr) |
PE (1) | PE20011064A1 (fr) |
PL (1) | PL357076A1 (fr) |
SK (1) | SK10622002A3 (fr) |
SV (1) | SV2002000290A (fr) |
TN (1) | TNSN01013A1 (fr) |
UY (1) | UY26550A1 (fr) |
WO (1) | WO2001055078A1 (fr) |
ZA (1) | ZA200205880B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI1045691T1 (en) * | 1997-12-12 | 2005-04-30 | Warner-Lambert Company Llc | Statin-carboxyalkylether combinations |
MXPA05001254A (es) * | 2002-08-22 | 2005-06-08 | Warner Lambert Co | Procedimiento para el tratamiento de la osteoartritis. |
JPWO2006115130A1 (ja) * | 2005-04-19 | 2008-12-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ビス[(2s)−3−[3−[(2s)−3−(4−クロロ−2−シアノフェノキシ)−2−フルオロプロポキシ]フェニル]−2−イソプロポキシプロピオン酸]カルシウム及びその中間体 |
US7816405B2 (en) | 2005-04-19 | 2010-10-19 | Eisai R&D Management Co., Ltd. | Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof |
US10227285B2 (en) * | 2014-11-14 | 2019-03-12 | Gemphire Therapeutics Inc. | Processes and intermediates for preparing alpha,omega-dicarboxylic acid-terminated dialkane ethers |
US20180297929A1 (en) * | 2017-04-18 | 2018-10-18 | Gemphire Therapeutics Inc. | Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor |
KR20210093900A (ko) * | 2018-10-18 | 2021-07-28 | 젬파이어 세러퓨틱스 인코포레이티드 | 젬카빈, 이의 약학적으로 허용가능한 염, 이의 조성물 및 이의 사용 방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
NZ503982A (en) | 1997-12-12 | 2002-03-28 | Warner Lambert Co | Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus |
-
2001
- 2001-01-11 AP APAP/P/2002/002587A patent/AP2002002587A0/en unknown
- 2001-01-11 AU AU22140/01A patent/AU2214001A/en not_active Abandoned
- 2001-01-11 DK DK01900037T patent/DK1259474T3/da active
- 2001-01-11 IL IL15054101A patent/IL150541A0/xx unknown
- 2001-01-11 PL PL01357076A patent/PL357076A1/xx not_active Application Discontinuation
- 2001-01-11 EP EP01900037A patent/EP1259474B1/fr not_active Expired - Lifetime
- 2001-01-11 CN CN01804045A patent/CN1395555A/zh active Pending
- 2001-01-11 BR BR0107763-5A patent/BR0107763A/pt not_active IP Right Cessation
- 2001-01-11 OA OA1200200226A patent/OA12166A/en unknown
- 2001-01-11 DE DE60138686T patent/DE60138686D1/de not_active Expired - Lifetime
- 2001-01-11 GE GE4872A patent/GEP20053428B/en unknown
- 2001-01-11 ES ES01900037T patent/ES2324281T3/es not_active Expired - Lifetime
- 2001-01-11 EA EA200200641A patent/EA004862B1/ru not_active IP Right Cessation
- 2001-01-11 SK SK1062-2002A patent/SK10622002A3/sk not_active Application Discontinuation
- 2001-01-11 HU HU0204422A patent/HUP0204422A3/hu unknown
- 2001-01-11 KR KR1020027009519A patent/KR20020073182A/ko not_active Application Discontinuation
- 2001-01-11 CZ CZ20022474A patent/CZ20022474A3/cs unknown
- 2001-01-11 JP JP2001555021A patent/JP4750995B2/ja not_active Expired - Fee Related
- 2001-01-11 CA CA002397960A patent/CA2397960C/fr not_active Expired - Lifetime
- 2001-01-11 DZ DZ013239A patent/DZ3239A1/fr active
- 2001-01-11 AT AT01900037T patent/ATE431326T1/de not_active IP Right Cessation
- 2001-01-11 MX MXPA02007223A patent/MXPA02007223A/es active IP Right Grant
- 2001-01-11 NZ NZ519550A patent/NZ519550A/en unknown
- 2001-01-11 WO PCT/IB2001/000026 patent/WO2001055078A1/fr not_active Application Discontinuation
- 2001-01-11 EE EEP200200404A patent/EE200200404A/xx unknown
- 2001-01-22 UY UY26550A patent/UY26550A1/es not_active Application Discontinuation
- 2001-01-22 SV SV2001000290A patent/SV2002000290A/es not_active Application Discontinuation
- 2001-01-23 AR ARP010100284A patent/AR029436A1/es unknown
- 2001-01-23 GT GT200100015A patent/GT200100015A/es unknown
- 2001-01-23 PA PA20018510601A patent/PA8510601A1/es unknown
- 2001-01-24 TN TNTNSN01013A patent/TNSN01013A1/fr unknown
- 2001-01-24 CO CO01005267A patent/CO5261537A1/es not_active Application Discontinuation
- 2001-01-24 HN HN2001000011A patent/HN2001000011A/es unknown
- 2001-01-24 PE PE2001000076A patent/PE20011064A1/es not_active Application Discontinuation
-
2002
- 2002-06-20 BG BG106851A patent/BG106851A/xx unknown
- 2002-06-25 IS IS6442A patent/IS6442A/is unknown
- 2002-07-22 MA MA26735A patent/MA26867A1/fr unknown
- 2002-07-23 ZA ZA200205880A patent/ZA200205880B/xx unknown
- 2002-07-24 NO NO20023526A patent/NO20023526L/no not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA27946A1 (fr) | Omega-carboxyaryldiphenyluree fluoro-substituee pour le traitement et la prevention de maladies et d'etats pathologiques. | |
CN101842360B (zh) | 抗感染嘧啶及其用途 | |
MA27774A1 (fr) | Inhibiteurs de phosphatidylinositol 3-kinase | |
MA30801B1 (fr) | Biaryl-ether-urees | |
TNSN96172A1 (fr) | Composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
TNSN00202A1 (fr) | Derives de n-[(purine - 2- yl) methyl]-sulfonamide nouveaux, procede pour leur preparation et compositions les contenant | |
MA26697A1 (fr) | Composes nouveaux inhibiteurs de gsk-3 et compositions pharmaceutiques les contenant | |
TNSN00203A1 (fr) | Derives de purine nouveaux, procede pour leur preparation et des compositions les contenant | |
TNSN99106A1 (fr) | Derives d'isothiazole nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
TNSN99156A1 (fr) | Derives d'acide hydroxypipecolate-hydroxamique nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
MA28747B1 (fr) | Dérivés de pyridine | |
UA77454C2 (en) | N-substituted hydroxypyrimidinone carboxamide inhibitors of hiv integrase | |
CN102803223A (zh) | 具有取代苯基的环状化合物 | |
MA25035A1 (fr) | Derives de 3-azabicyclo [3,1,0] hexane nouveaux, procede pour leur preparation et compositions les contenant | |
MA28271A1 (fr) | Dérivés de benzènesulfonylamino-pyridine -2-yle et composés apparentés servant d'inhibiteurs de la 11-bêta- hydroxystéroïde-déshydrogénase de type 1(11-bêta-HSD-1)pour le traitement du diabète et de l'obésité | |
MA26864A1 (fr) | Antagonistes du facteur de liberation de corticotrophine. | |
TNSN05250A1 (fr) | Pyrimidinones substituees | |
TNSN99031A1 (fr) | Composes heterocycliques nouveaux inhibiteurs de romatases, procede pour leur preparation et compositions pharmaceutiques les contenant | |
CN101084224A (zh) | 具有杀真菌活性的噻吩并-嘧啶化合物 | |
TNSN98024A1 (fr) | 2-amino-6-(2-substitue-4-phenoxy)-substitue-pyridines, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
MA26696A1 (fr) | Derives de tetrahydrobenzazepine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
TNSN01126A1 (fr) | Imidazoles substitues nouveaux, procede pour leur preparation et compositions les contenant | |
GB2196962A (en) | Substituted 2-benzyl-mercapto-imidazoles and analogs useful as anti-inflammatory agents | |
MA26867A1 (fr) | Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composés | |
TNSN01094A1 (fr) | Derives de 3-azabicyclo [3,1,0] hexane nouveaux, procede pour leur preparation et compositions les contenant |