AR029436A1 - Compuestos de eteres de dicarboxilato de calcio, metodos para su preparacion y su uso en tratamiento de las enfermedades vasculares y diabetes, composicion farmaceutica, formas cristalinas. - Google Patents
Compuestos de eteres de dicarboxilato de calcio, metodos para su preparacion y su uso en tratamiento de las enfermedades vasculares y diabetes, composicion farmaceutica, formas cristalinas.Info
- Publication number
- AR029436A1 AR029436A1 ARP010100284A ARP010100284A AR029436A1 AR 029436 A1 AR029436 A1 AR 029436A1 AR P010100284 A ARP010100284 A AR P010100284A AR P010100284 A ARP010100284 A AR P010100284A AR 029436 A1 AR029436 A1 AR 029436A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- compounds
- eteres
- diabetes
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Los solventes de alcohol y agua de la sal de mono-calcio del ácido 6-(5-carboxi-5metil-hexiloxi)-2,2-dimetilhexanoico son cristalinos y tienen la formula (1), donde R1 es H o alquilo inferior y x es un numero de 0 a 10, y son utiles para tratar la dislipidemia. Se describen también formas cristalinas, procesos para su preparacion, su uso en la preparacion de medicamentos y composiciones farmacéuticas. Estos compuestos son utiles para la regulacion de lípidos plasmáticos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17782300P | 2000-01-25 | 2000-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR029436A1 true AR029436A1 (es) | 2003-06-25 |
Family
ID=22650106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010100284A AR029436A1 (es) | 2000-01-25 | 2001-01-23 | Compuestos de eteres de dicarboxilato de calcio, metodos para su preparacion y su uso en tratamiento de las enfermedades vasculares y diabetes, composicion farmaceutica, formas cristalinas. |
Country Status (39)
| Country | Link |
|---|---|
| EP (1) | EP1259474B1 (es) |
| JP (1) | JP4750995B2 (es) |
| KR (1) | KR20020073182A (es) |
| CN (1) | CN1395555A (es) |
| AP (1) | AP2002002587A0 (es) |
| AR (1) | AR029436A1 (es) |
| AT (1) | ATE431326T1 (es) |
| AU (1) | AU2214001A (es) |
| BG (1) | BG106851A (es) |
| BR (1) | BR0107763A (es) |
| CA (1) | CA2397960C (es) |
| CO (1) | CO5261537A1 (es) |
| CZ (1) | CZ20022474A3 (es) |
| DE (1) | DE60138686D1 (es) |
| DK (1) | DK1259474T3 (es) |
| DZ (1) | DZ3239A1 (es) |
| EA (1) | EA004862B1 (es) |
| EE (1) | EE200200404A (es) |
| ES (1) | ES2324281T3 (es) |
| GE (1) | GEP20053428B (es) |
| GT (1) | GT200100015A (es) |
| HN (1) | HN2001000011A (es) |
| HU (1) | HUP0204422A3 (es) |
| IL (1) | IL150541A0 (es) |
| IS (1) | IS6442A (es) |
| MA (1) | MA26867A1 (es) |
| MX (1) | MXPA02007223A (es) |
| NO (1) | NO20023526L (es) |
| NZ (1) | NZ519550A (es) |
| OA (1) | OA12166A (es) |
| PA (1) | PA8510601A1 (es) |
| PE (1) | PE20011064A1 (es) |
| PL (1) | PL357076A1 (es) |
| SK (1) | SK10622002A3 (es) |
| SV (1) | SV2002000290A (es) |
| TN (1) | TNSN01013A1 (es) |
| UY (1) | UY26550A1 (es) |
| WO (1) | WO2001055078A1 (es) |
| ZA (1) | ZA200205880B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1045691T1 (en) * | 1997-12-12 | 2005-04-30 | Warner-Lambert Company Llc | Statin-carboxyalkylether combinations |
| PL375742A1 (en) * | 2002-08-22 | 2005-12-12 | Warner-Lambert Company Llc | Method of treating osteoarthritis |
| US7816405B2 (en) | 2005-04-19 | 2010-10-19 | Eisai R&D Management Co., Ltd. | Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof |
| WO2006115130A1 (ja) * | 2005-04-19 | 2006-11-02 | Eisai R & D Management Co., Ltd. | ビス［（２ｓ）－３－［３－［（２ｓ）－３－（４－クロロ－２－シアノフェノキシ）－２－フルオロプロポキシ］フェニル］－２－イソプロポキシプロピオン酸］カルシウム及びその中間体 |
| MX2017006200A (es) * | 2014-11-14 | 2017-11-17 | Gemphire Therapeutics Inc | Procesos e intermediarios para preparar dialcano eteres terminados con acido a, ?-dicarboxilico. |
| CA3059073A1 (en) * | 2017-04-18 | 2018-10-25 | Daniela Carmen Oniciu | Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor |
| KR20210093900A (ko) * | 2018-10-18 | 2021-07-28 | 젬파이어 세러퓨틱스 인코포레이티드 | 젬카빈, 이의 약학적으로 허용가능한 염, 이의 조성물 및 이의 사용 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
| NZ503982A (en) | 1997-12-12 | 2002-03-28 | Warner Lambert Co | Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus |
-
2001
- 2001-01-11 KR KR1020027009519A patent/KR20020073182A/ko not_active Application Discontinuation
- 2001-01-11 SK SK1062-2002A patent/SK10622002A3/sk not_active Application Discontinuation
- 2001-01-11 IL IL15054101A patent/IL150541A0/xx unknown
- 2001-01-11 NZ NZ519550A patent/NZ519550A/en unknown
- 2001-01-11 JP JP2001555021A patent/JP4750995B2/ja not_active Expired - Fee Related
- 2001-01-11 EE EEP200200404A patent/EE200200404A/xx unknown
- 2001-01-11 ES ES01900037T patent/ES2324281T3/es not_active Expired - Lifetime
- 2001-01-11 EA EA200200641A patent/EA004862B1/ru not_active IP Right Cessation
- 2001-01-11 EP EP01900037A patent/EP1259474B1/en not_active Expired - Lifetime
- 2001-01-11 WO PCT/IB2001/000026 patent/WO2001055078A1/en not_active Application Discontinuation
- 2001-01-11 PL PL01357076A patent/PL357076A1/xx not_active Application Discontinuation
- 2001-01-11 MX MXPA02007223A patent/MXPA02007223A/es active IP Right Grant
- 2001-01-11 CZ CZ20022474A patent/CZ20022474A3/cs unknown
- 2001-01-11 DK DK01900037T patent/DK1259474T3/da active
- 2001-01-11 AP APAP/P/2002/002587A patent/AP2002002587A0/en unknown
- 2001-01-11 DE DE60138686T patent/DE60138686D1/de not_active Expired - Lifetime
- 2001-01-11 DZ DZ013239A patent/DZ3239A1/fr active
- 2001-01-11 BR BR0107763-5A patent/BR0107763A/pt not_active IP Right Cessation
- 2001-01-11 OA OA1200200226A patent/OA12166A/en unknown
- 2001-01-11 HU HU0204422A patent/HUP0204422A3/hu unknown
- 2001-01-11 AU AU22140/01A patent/AU2214001A/en not_active Abandoned
- 2001-01-11 AT AT01900037T patent/ATE431326T1/de not_active IP Right Cessation
- 2001-01-11 GE GE4872A patent/GEP20053428B/en unknown
- 2001-01-11 CA CA002397960A patent/CA2397960C/en not_active Expired - Lifetime
- 2001-01-11 CN CN01804045A patent/CN1395555A/zh active Pending
- 2001-01-22 SV SV2001000290A patent/SV2002000290A/es not_active Application Discontinuation
- 2001-01-22 UY UY26550A patent/UY26550A1/es not_active Application Discontinuation
- 2001-01-23 PA PA20018510601A patent/PA8510601A1/es unknown
- 2001-01-23 AR ARP010100284A patent/AR029436A1/es unknown
- 2001-01-23 GT GT200100015A patent/GT200100015A/es unknown
- 2001-01-24 PE PE2001000076A patent/PE20011064A1/es not_active Application Discontinuation
- 2001-01-24 TN TNTNSN01013A patent/TNSN01013A1/fr unknown
- 2001-01-24 HN HN2001000011A patent/HN2001000011A/es unknown
- 2001-01-24 CO CO01005267A patent/CO5261537A1/es not_active Application Discontinuation
-
2002
- 2002-06-20 BG BG106851A patent/BG106851A/xx unknown
- 2002-06-25 IS IS6442A patent/IS6442A/is unknown
- 2002-07-22 MA MA26735A patent/MA26867A1/fr unknown
- 2002-07-23 ZA ZA200205880A patent/ZA200205880B/xx unknown
- 2002-07-24 NO NO20023526A patent/NO20023526L/no not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200601584A1 (ru) | Замещённые глюкопиранозилом бензольные производные, содержащие эти соединения лекарственные средства, их применение и способ их получения | |
| DOP2006000084A (es) | Compuestos sulfoximino-macrociclicos y sus sales, composiciones farmaceuticas que comprenden dichos compuestos, metodos de preparacion y usos de los mismos | |
| AR033499A1 (es) | Derivado de quinazolina, proceso para su preparacion, composicion farmaceutica que lo comprende y su uso en la fabricacion de medicamentos para usar en la produccion de un efecto antiangeogenico y/o reductor de la permeabilidad vascular en un animal de sangre caliente | |
| AR029383A1 (es) | Moleculas pequenas, los intermediarios para su sintesis, las composiciones farmaceuticas que las contienen y su uso para preparar un medicamento destinado al tratamiento o la profilaxis de enfermedades inflamatorias o mediadas por celulas inmunes | |
| ECSP034732A (es) | Derivado de fenetanolamina para el tratamiento de enfermedades respiratorias | |
| ATE411280T1 (de) | Phenoxyessigsäure-derivate zur behandlung von störungen der atemwege | |
| BR9916790A (pt) | Uso de um composto, composto, processo para amanufatura do mesmo, composição farmacêtica, e,método para produzir um efeito de dano vascularem um animal de sangue quente | |
| AR041932A1 (es) | Derivados de ciclohexano espirociclicos, preparacion de los mismos, su uso en la fabricacion de medicamentos y dichos medicamentos. | |
| AR037517A1 (es) | Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria | |
| AR031248A1 (es) | Compuestos de ditosilato de quinazolina, composicion farmaceutica, metodo de tratamiento y uso en terapia y proceso para la preparacion de dichos compuestos | |
| CL2003002683A1 (es) | Enantiomeros s de compuestos derivados del acido (2s)-3-4(-{2-amino-2-oxoetoxi}fenil)-2-etoxipropanoico; proceso de preparacion; compuestos intermediarios; composicion farmaceutica; y su uso para el tratamiento o prevencion de trastornos de lipidos, | |
| AR032136A1 (es) | Compuestos espiroheterociclicos utiles como inhibidores reversibles de cisteina-proteasas | |
| AR038955A1 (es) | Compuestos de pirimidinona y piridona sustituidos y metodos para su uso | |
| GT200400116A (es) | Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades. | |
| EA200601846A1 (ru) | Содержащие бензоксазины лекарственные комбинации для лечения заболеваний дыхательных путей | |
| BRPI0411673A (pt) | composto, sal farmaceuticamente aceitável, composição farmacêutica, e, uso de um composto | |
| IT1251166B (it) | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono | |
| ES2038172T3 (es) | Procedimiento para preparar carboxamidas heterociclicas. | |
| AR029436A1 (es) | Compuestos de eteres de dicarboxilato de calcio, metodos para su preparacion y su uso en tratamiento de las enfermedades vasculares y diabetes, composicion farmaceutica, formas cristalinas. | |
| MX9307363A (es) | Compuestos de 2-nitroarilo y 2-cianoarilo y composiciones farmaceuticas que los contienen. | |
| ATE427944T1 (de) | Isoflavonderivative von tectoridin, deren herstellung und antivirale medikamente, die diese als wirksame bestandteile enthalten | |
| AR035465A1 (es) | Compuestos de imidazopiridina, procesos para su preparacion,formulacion farmaceutica, usos de estos compuestos para la fabricacion de medicamentos e intermediarios | |
| PA8525801A1 (es) | Compuestos de pirazol, composiciones farmacéuticas, y métodos para modular y/o inhibir la actividad de erab/hadh2 | |
| ES2318023T3 (es) | Uso de derivados de acidos 2,5-dihidroxibenceno-sulfonicos en la elaboracion de un medicamento para potenciar el efecto de otros farmacos en el tratamiento de la disfuncion erectil. | |
| AR032622A1 (es) | Compuestos de 4-amino-azepan-3-ona, composiciones farmaceuticas que los comprenden, intermediarios utiles en la sintesis de tales compuestos, procedimiento para la sintesis de dichos compuestos, y uso de tales compuestos en la fabricacion de medicamentos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |