ZA200205880B - Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith. - Google Patents

Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith.

Info

Publication number
ZA200205880B
ZA200205880B ZA200205880A ZA200205880A ZA200205880B ZA 200205880 B ZA200205880 B ZA 200205880B ZA 200205880 A ZA200205880 A ZA 200205880A ZA 200205880 A ZA200205880 A ZA 200205880A ZA 200205880 B ZA200205880 B ZA 200205880B
Authority
ZA
South Africa
Prior art keywords
treatment
methods
vascular disease
making same
diabetes
Prior art date
Application number
ZA200205880A
Other languages
English (en)
Inventor
Howard Yoshihisa Ando
Donald Eugene Butler
Gary Jay Dozeman
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA200205880B publication Critical patent/ZA200205880B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
ZA200205880A 2000-01-25 2002-07-23 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith. ZA200205880B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17782300P 2000-01-25 2000-01-25

Publications (1)

Publication Number Publication Date
ZA200205880B true ZA200205880B (en) 2003-07-23

Family

ID=22650106

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200205880A ZA200205880B (en) 2000-01-25 2002-07-23 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith.

Country Status (39)

Country Link
EP (1) EP1259474B1 (fr)
JP (1) JP4750995B2 (fr)
KR (1) KR20020073182A (fr)
CN (1) CN1395555A (fr)
AP (1) AP2002002587A0 (fr)
AR (1) AR029436A1 (fr)
AT (1) ATE431326T1 (fr)
AU (1) AU2214001A (fr)
BG (1) BG106851A (fr)
BR (1) BR0107763A (fr)
CA (1) CA2397960C (fr)
CO (1) CO5261537A1 (fr)
CZ (1) CZ20022474A3 (fr)
DE (1) DE60138686D1 (fr)
DK (1) DK1259474T3 (fr)
DZ (1) DZ3239A1 (fr)
EA (1) EA004862B1 (fr)
EE (1) EE200200404A (fr)
ES (1) ES2324281T3 (fr)
GE (1) GEP20053428B (fr)
GT (1) GT200100015A (fr)
HN (1) HN2001000011A (fr)
HU (1) HUP0204422A3 (fr)
IL (1) IL150541A0 (fr)
IS (1) IS6442A (fr)
MA (1) MA26867A1 (fr)
MX (1) MXPA02007223A (fr)
NO (1) NO20023526L (fr)
NZ (1) NZ519550A (fr)
OA (1) OA12166A (fr)
PA (1) PA8510601A1 (fr)
PE (1) PE20011064A1 (fr)
PL (1) PL357076A1 (fr)
SK (1) SK10622002A3 (fr)
SV (1) SV2002000290A (fr)
TN (1) TNSN01013A1 (fr)
UY (1) UY26550A1 (fr)
WO (1) WO2001055078A1 (fr)
ZA (1) ZA200205880B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1481962A1 (fr) * 1997-12-12 2004-12-01 Warner-Lambert Company LLC Nouveau carboxyéthylether reduisant la cholesterolémie
KR20050058454A (ko) * 2002-08-22 2005-06-16 워너-램버트 캄파니 엘엘씨 골관절염의 치료 방법
US7816405B2 (en) 2005-04-19 2010-10-19 Eisai R&D Management Co., Ltd. Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof
WO2006115130A1 (fr) * 2005-04-19 2006-11-02 Eisai R & D Management Co., Ltd. Bis[(2s)-3-[3-[(2s)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate] de calcium et intermediaire de celui-ci
KR20170083535A (ko) * 2014-11-14 2017-07-18 젬파이어 세러퓨틱스 인코포레이티드 α,ω-다이카복실산-말단 다이알케인 에터를 제조하기 위한 방법 및 중간체
US20180297929A1 (en) * 2017-04-18 2018-10-18 Gemphire Therapeutics Inc. Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor
WO2020081837A1 (fr) * 2018-10-18 2020-04-23 Gemphire Therapeutics Inc. Gemcabène, sels pharmaceutiquement acceptables de celui-ci, compositions correspondantes et procédés d'utilisation associés

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648387A (en) 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
NZ503982A (en) 1997-12-12 2002-03-28 Warner Lambert Co Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus

Also Published As

Publication number Publication date
CA2397960A1 (fr) 2001-08-02
CN1395555A (zh) 2003-02-05
HUP0204422A3 (en) 2003-08-28
OA12166A (en) 2003-11-07
CA2397960C (fr) 2008-09-09
IL150541A0 (en) 2003-02-12
IS6442A (is) 2002-06-25
JP4750995B2 (ja) 2011-08-17
KR20020073182A (ko) 2002-09-19
PE20011064A1 (es) 2001-10-22
TNSN01013A1 (fr) 2005-11-10
EA004862B1 (ru) 2004-08-26
MXPA02007223A (es) 2002-11-29
EP1259474A1 (fr) 2002-11-27
EA200200641A1 (ru) 2002-12-26
WO2001055078A1 (fr) 2001-08-02
HUP0204422A2 (en) 2003-05-28
ATE431326T1 (de) 2009-05-15
MA26867A1 (fr) 2004-12-20
DE60138686D1 (de) 2009-06-25
HN2001000011A (es) 2001-06-13
PL357076A1 (en) 2004-07-12
EE200200404A (et) 2003-10-15
AU2214001A (en) 2001-08-07
JP2003520835A (ja) 2003-07-08
AP2002002587A0 (en) 2002-09-30
AR029436A1 (es) 2003-06-25
NZ519550A (en) 2003-11-28
PA8510601A1 (es) 2002-08-26
ES2324281T3 (es) 2009-08-04
SV2002000290A (es) 2002-07-16
EP1259474B1 (fr) 2009-05-13
GEP20053428B (en) 2005-01-25
CZ20022474A3 (cs) 2003-06-18
NO20023526L (no) 2002-08-27
DZ3239A1 (fr) 2001-08-02
GT200100015A (es) 2001-10-19
BG106851A (en) 2003-01-31
DK1259474T3 (da) 2009-07-20
NO20023526D0 (no) 2002-07-24
UY26550A1 (es) 2001-08-27
BR0107763A (pt) 2002-11-12
SK10622002A3 (sk) 2003-07-01
CO5261537A1 (es) 2003-03-31

Similar Documents

Publication Publication Date Title
AP2004003002A0 (en) azabicyclic-substituted fused-heteroaryl compoundsfor the treatment of disease.
DE60023043D1 (de) (S,S)-Reboxetin zur Behandlung von Inkontinenz
ZA200108218B (en) Vascular surgery.
EP1374935A4 (fr) Aiguille de seringue medicale et procede de production de cette aiguille
AU2002323258A1 (en) Diagnosis and treatment of vascular disease
MXPA03000069A (es) COMPOSICION PARA TRATAMIENTO DE TELAS CON ENJUAGUE AnADIDO, EQUIPO QUE CONTIENE LA MISMA Y METODO DE USO PARA LA MISMA.
MX238203B (es) Tratamiento de semillas con combinaciones de piretrinas, piretroides y tlametoxam.
AU2002367535A1 (en) Diagnosis and treatment of vascular disease
MXPA03009300A (es) Articulos absorbentes de tipo de calzoncillo y metodos para hacer tales articulos absorbentes.
EP1790728A3 (fr) Imagerie, diagnostic et traitement de maladie
MX233159B (es) Composiciones para tratamientos de telas.
ZA200205880B (en) Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith.
AU2002326813A1 (en) Diagnosis and treatment of vascular disease
WO2001060343A3 (fr) Utilisation d'acide 2-methyl-thiazolidin-2,4-dicarboxylique (2-mtdc) et/ou de ses sels physiologiquement compabibles pour le traitement et/ou la prevention de cancers
MXPA02006511A (es) Complejo que comprende factor inhibidor de osteoclastogenesis y polisacarido.
AU2002341880A1 (en) Diagnosis and treatment of vascular disease
HK1048475A1 (en) Novel xanthone compounds, their preparation and use as medicament.
HUP0300222A3 (en) Novel lhrh-antagonists, production and use thereof as medicament
EP1318819A4 (fr) Traitements de traumas et autres indications
AU2002341604A1 (en) Diagnosis and treatment of vascular disease
EP1591113A4 (fr) Agent abaissant la pression arterielle, agent ameliorant la souplesse vasculaire et aliments possedant de telles proprietes
EG23209A (en) Durable press treatment of fabric.
EP1435962A4 (fr) Traitement du diabete de type i
MXPA03000033A (es) Procedimiento de tratamiento de enfermedades vasculares perifericas, neuropatias perifericas y neuropatias autonomicas.
AU2001277737A1 (en) Novel substance having physiological activity, process for producing the same, and use