MA19513A1 - Nouvelles imidazo (1,2-a) pyridines et pyrazines - Google Patents

Nouvelles imidazo (1,2-a) pyridines et pyrazines

Info

Publication number
MA19513A1
MA19513A1 MA19720A MA19720A MA19513A1 MA 19513 A1 MA19513 A1 MA 19513A1 MA 19720 A MA19720 A MA 19720A MA 19720 A MA19720 A MA 19720A MA 19513 A1 MA19513 A1 MA 19513A1
Authority
MA
Morocco
Prior art keywords
pyrazines
pyridines
new imidazo
imidazo
new
Prior art date
Application number
MA19720A
Other languages
English (en)
French (fr)
Inventor
J A Bristol
Chester Puchalski
Raymond George Lovey
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/356,052 external-priority patent/US4507294A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of MA19513A1 publication Critical patent/MA19513A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA19720A 1981-06-26 1982-06-24 Nouvelles imidazo (1,2-a) pyridines et pyrazines MA19513A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27757681A 1981-06-26 1981-06-26
US06/356,052 US4507294A (en) 1982-03-08 1982-03-08 Imidazo[1,2-a]pyrazines

Publications (1)

Publication Number Publication Date
MA19513A1 true MA19513A1 (fr) 1982-12-31

Family

ID=26958574

Family Applications (1)

Application Number Title Priority Date Filing Date
MA19720A MA19513A1 (fr) 1981-06-26 1982-06-24 Nouvelles imidazo (1,2-a) pyridines et pyrazines

Country Status (18)

Country Link
US (1) US4450164A (enExample)
EP (1) EP0068378B1 (enExample)
KR (1) KR880001718B1 (enExample)
AU (1) AU556062B2 (enExample)
DE (1) DE3269604D1 (enExample)
DK (1) DK284482A (enExample)
ES (1) ES513431A0 (enExample)
FI (1) FI73433C (enExample)
GR (1) GR74924B (enExample)
HU (1) HU189595B (enExample)
IE (1) IE53324B1 (enExample)
IL (1) IL66141A0 (enExample)
MA (1) MA19513A1 (enExample)
MY (1) MY8700624A (enExample)
NO (1) NO159724C (enExample)
NZ (1) NZ201066A (enExample)
OA (1) OA07130A (enExample)
PT (1) PT75115B (enExample)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8305245D0 (en) * 1983-02-25 1983-03-30 Fujisawa Pharmaceutical Co Imidazo-heterocyclic compounds
US4507481A (en) * 1983-07-29 1985-03-26 Pennwalt Corporation Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines
US4578387A (en) * 1984-03-05 1986-03-25 Eli Lilly And Company Inotropic agents
GB8415540D0 (en) * 1984-06-18 1984-07-25 Fujisawa Pharmaceutical Co Imidazoisoquinoline compounds
JPS61218589A (ja) * 1985-03-26 1986-09-29 Eisai Co Ltd ５―（６―イミダゾ〔１，２―ａ〕ピリジニル）ピリジン誘導体
DE3516458A1 (de) * 1985-05-08 1986-11-13 W. Schlafhorst & Co, 4050 Mönchengladbach Angetriebener fadenspeicher
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
US4596872A (en) * 1985-06-05 1986-06-24 Schering A.G. Imidazo[1,2-a]pyridines, and process for their preparation
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
US4727145A (en) * 1986-09-22 1988-02-23 Ortho Pharmaceutical Corporation 2- Or 3- aryl substituted imidazo [1,2-a]pyridines
US4791117A (en) * 1986-09-22 1988-12-13 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines and their use as calcium channel blockers
EP0266890A1 (en) * 1986-10-07 1988-05-11 Yamanouchi Pharmaceutical Co. Ltd. Imidazopyridine derivatives, their production, and pharmaceutical compositions containing them
US4831041A (en) * 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
IL86269A0 (en) * 1987-05-08 1988-11-15 Byk Gulden Lomberg Chem Fab Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
AT390438B (de) * 1987-10-08 1990-05-10 Yamanouchi Pharma Co Ltd Neue imidazo(1,2-a)pyridinderivate und deren herstellung und diese enthaltende pharmazeutische zubereitungen
SE8704248D0 (sv) * 1987-10-30 1987-10-30 Haessle Ab Medical use
US5716964A (en) * 1989-12-04 1998-02-10 G.D. Searle & Co. Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
IE904346A1 (en) * 1989-12-04 1991-06-05 Searle & Co IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF¹NEUROTOXIC INJURY
KR910011852A (ko) * 1989-12-04 1991-08-07 폴 디. 매튜카이티스 신경독 장해 치료용 이미다조[1,2-a]피리디닐알킬 화합물
DE4010797A1 (de) * 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
US5041442A (en) * 1990-07-31 1991-08-20 Syntex (U.S.A.) Inc. Pyrrolo(1,2-a)pyrazines as inhibitors of gastric acid secretion
US5475027A (en) * 1990-11-19 1995-12-12 G.D. Searle & Co. Retroviral protease inhibitors
US5614522A (en) * 1990-11-19 1997-03-25 G.D. Searle & Co. Retroviral protease inhibitors
US5475013A (en) * 1990-11-19 1995-12-12 Monsanto Company Retroviral protease inhibitors
US5482947A (en) * 1990-11-19 1996-01-09 Talley; John J. Retroviral protease inhibitors
EP1148050A1 (en) * 1992-05-21 2001-10-24 Monsanto Company Retroviral protease inhibitors
US5464843A (en) * 1992-06-23 1995-11-07 G.D. Searle & Co. Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
ES2123065T3 (es) * 1992-08-25 1999-01-01 Searle & Co Hidroxietilamino-sulfonamidas utiles como inhibidores de proteasas retroviricas.
DE69311810T2 (de) * 1992-08-25 1997-11-27 Monsanto Co N-(alkanoylamino-2-hydroxypropyl)-sulfonamide verwendbar als retrovirale proteaseninhibitoren
RU2146668C1 (ru) * 1992-08-25 2000-03-20 Джи Ди Сирл энд Компани Сульфонилалканоиламино-гидроксиэтиламино-сульфонамидное соединение, фармацевтические композиции и способы лечения и ингибирования ретровирусных протеаз
US5760076A (en) * 1992-08-25 1998-06-02 G.D Searle & Co. Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
US6022994A (en) * 1992-08-25 2000-02-08 G. D. Searle &. Co. Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
US5968942A (en) 1992-08-25 1999-10-19 G. D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
US7141609B2 (en) * 1992-08-25 2006-11-28 G.D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
US6046190A (en) * 1992-08-25 2000-04-04 G.D. Searle & Co. Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors
US5830897A (en) * 1992-08-27 1998-11-03 G. D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
ATE211462T1 (de) 1992-10-30 2002-01-15 Searle & Co N-substituierte hydroxyethylaminosulfamidsäure- derivate verwendbar als inhibitoren retroviraler proteasen
EP0885880A3 (en) * 1992-10-30 1999-10-06 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfamic acids useful as retroviral protease inhibitors
US5756498A (en) * 1992-10-30 1998-05-26 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors
US5578606A (en) 1992-10-30 1996-11-26 G. D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors
US6337398B1 (en) * 1992-10-30 2002-01-08 G.D. Searle & Co. Succinoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors
US5574042A (en) * 1992-11-02 1996-11-12 Fujisawa Pharmaceutical Co., Ltd Imidazo [1,2-a] pyridines and their pharmaceutical use
US5514801A (en) * 1992-12-29 1996-05-07 Monsanto Company Cyclic sulfone containing retroviral protease inhibitors
HUT74170A (en) * 1993-07-06 1996-11-28 Pfizer Bicyclic tetrahydro pyrazolopyridines
US5602119A (en) * 1993-10-29 1997-02-11 Vazquez; Michael L. Succinoylamino hydroxyethylamino sulfamic acid derivatives useful as retroviral protease inhibitors
US6133444A (en) * 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
WO1996003405A1 (de) * 1994-07-28 1996-02-08 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazopyridin-azolidinone
US5831117A (en) * 1995-01-20 1998-11-03 G. D. Searle & Co. Method of preparing retroviral protease inhibitor intermediates
US6140505A (en) 1995-03-10 2000-10-31 G. D. Searle & Co. Synthesis of benzo fused heterocyclic sulfonyl chlorides
US5756533A (en) * 1995-03-10 1998-05-26 G.D. Searle & Co. Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US6150556A (en) 1995-03-10 2000-11-21 G. D. Dearle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US5705500A (en) * 1995-03-10 1998-01-06 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US6407134B1 (en) * 1995-03-10 2002-06-18 G. D. Searle & Co. Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US5985870A (en) * 1995-03-10 1999-11-16 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US6667307B2 (en) 1997-12-19 2003-12-23 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
BR9607625A (pt) 1995-03-10 1999-06-15 Searle & Co Inibidores de protease retroviral sulfonamida hidroxietilamino de aminoácido heterociclocarbonila
US6861539B1 (en) 1995-03-10 2005-03-01 G. D. Searle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US7339078B2 (en) * 1995-03-10 2008-03-04 G.D. Searle Llc Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
EP1188766A1 (en) 1995-03-10 2002-03-20 G.D. Searle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US5776971A (en) * 1995-03-10 1998-07-07 G.D. Searle & Co. Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US6169085B1 (en) 1995-03-10 2001-01-02 G. D. Searle & Company Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
CN1064360C (zh) * 1995-04-21 2001-04-11 新日本药品株式会社 稠合咪唑并[1,2－a]吡啶类
US5753660A (en) * 1995-11-15 1998-05-19 G. D. Searle & Co. Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
KR100490790B1 (ko) * 1997-08-11 2005-09-12 주식회사 휴비스 모세관냉각장치를이용한단성분중공자발권축섬유의제조방법
SE9704404D0 (sv) * 1997-11-28 1997-11-28 Astra Ab New compounds
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
EP1095022A1 (en) 1998-07-08 2001-05-02 G.D. Searle & Co. Retroviral protease inhibitors
SE9802793D0 (sv) 1998-08-21 1998-08-21 Astra Ab New compounds
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
EP1218382B1 (de) 1999-10-08 2004-01-28 Grünenthal GmbH Bicyclische imidazo-3-yl-aminderivate
DE19948434A1 (de) * 1999-10-08 2001-06-07 Gruenenthal Gmbh Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
DE19948437A1 (de) * 1999-10-08 2001-06-07 Gruenenthal Gmbh Am Sechsring substituierte, bicyclische Imidazo-3-aminderivate
DE50004817D1 (de) 1999-10-08 2004-01-29 Gruenenthal Gmbh Am sechsring substituierte, bicyclische imidazo-3-yl-aminderivate
DE10019714A1 (de) * 2000-04-20 2002-01-10 Gruenenthal Gmbh Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen
CA2311483A1 (en) * 2000-06-12 2001-12-12 Gregory N Beatch IMIDAZO [1,2-A] PYRIDINIC ETHERS AND USES THEREOF
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
DE10050663A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Verwendung von substituierten Imidazo[1,2-a]pyridin-, -pyrimidin- und pyrazin-3-yl-amin-Derivaten zur Herstellung von Medikamenten zur NOS-Inhibierung
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
TWI312347B (en) 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
MXPA03007888A (es) * 2001-03-08 2003-12-04 Astrazeneca Ab Compuestos para tratamiento y prevencion de ulcera gastrica inducida por medicamentos.
DE10117184A1 (de) * 2001-04-05 2002-10-17 Gruenenthal Gmbh Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen
DE10117183A1 (de) * 2001-04-05 2002-10-10 Gruenenthal Gmbh Verwendung von substituierten Imidazo[1,2-a]-pyridinverbindungen als Arzneimittel
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
DE10145457A1 (de) 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US20050064076A1 (en) * 2003-09-22 2005-03-24 Fmc Technologies, Inc. Method of measuring volatile components of foods
DE102004021716A1 (de) * 2004-04-30 2005-12-01 Grünenthal GmbH Substituierte Imidazo[1,2-a]pyridin-Verbindungen und Arzneimittel enthaltend substituierte Imidazo[1,2-a]pyridin-Verbindungen
CA2579127C (en) 2004-09-03 2011-08-02 Yuhan Corporation Pyrrolo[3,2-b]pyridine derivatives and processes for the preparation thereof
ATE518858T1 (de) * 2004-09-03 2011-08-15 Yuhan Corp Pyrroloä3,2-cüpyridinderivate und herstellungsverfahren dafür
CA2579083C (en) * 2004-09-03 2011-06-14 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
KR100958829B1 (ko) 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
WO2008015196A1 (en) * 2006-07-31 2008-02-07 Nycomed Gmbh 5-,7-bis-substituted imidazo[1,2-a]pyridines
EP2266990B1 (en) 2008-04-15 2012-09-26 Eisai R&D Management Co., Ltd. 3-PHENYLPYRAZOLO[5,1-b]THIAZOLE COMPOUND
JP2011530511A (ja) * 2008-08-05 2011-12-22 メルク・シャープ・エンド・ドーム・コーポレイション 治療用化合物
EP2334675B1 (en) * 2008-09-16 2014-03-26 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
NZ598220A (en) 2009-08-17 2014-02-28 Intellikine Llc Heterocyclic compounds and uses thereof
AR078521A1 (es) 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
US8722026B2 (en) * 2010-01-06 2014-05-13 Elc Management, Llc Skin lightening compositions
US9403820B2 (en) 2011-11-11 2016-08-02 Intellikine Llc Kinase inhibitor polymorphs
EP2881394B1 (en) 2012-07-31 2018-03-21 Kyowa Hakko Kirin Co., Ltd. Condensed ring heterocyclic compound
CA3102279A1 (en) 2018-06-01 2019-12-05 Cornell University Combination therapy for pi3k-associated disease or disorder
EP4596548A1 (en) * 2024-02-05 2025-08-06 Ludwig-Maximilians-Universität Nurr1 modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701780A (en) * 1970-09-18 1972-10-31 Merck & Co Inc Imidazo(1,2-a)pyridines
US4044015A (en) * 1975-09-03 1977-08-23 Pfizer Inc. Imidazopyridinium compounds as hypoglycemic agents
US4177274A (en) * 1975-12-09 1979-12-04 Merck & Co., Inc. Substituted imidazo [1,2-a] pyridines
US4092321A (en) * 1977-06-16 1978-05-30 Merck & Co., Inc. Process for the preparation of imidazo [1,2-a] pyridines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FI73433C (fi) 1987-10-09
IE53324B1 (en) 1988-10-12
HU189595B (en) 1986-07-28
DE3269604D1 (en) 1986-04-10
PT75115B (en) 1985-06-28
DK284482A (da) 1982-12-27
US4450164A (en) 1984-05-22
MY8700624A (en) 1987-12-31
IE821515L (en) 1982-12-26
ES8307806A1 (es) 1983-08-01
AU8517882A (en) 1983-01-06
GR74924B (enExample) 1984-07-12
FI822266A0 (fi) 1982-06-24
PT75115A (en) 1982-07-01
EP0068378B1 (en) 1986-03-05
NO822128L (no) 1982-12-27
IL66141A0 (en) 1982-09-30
EP0068378A1 (en) 1983-01-05
FI73433B (fi) 1987-06-30
KR840000546A (ko) 1984-02-25
NO159724C (no) 1989-02-01
NO159724B (no) 1988-10-24
KR880001718B1 (ko) 1988-09-08
OA07130A (fr) 1984-03-31
ES513431A0 (es) 1983-08-01
AU556062B2 (en) 1986-10-23
NZ201066A (en) 1985-08-16
FI822266L (fi) 1982-12-27

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