LV13141B - Hiv protease inhibitors in pharmaceutical combinations for the treatment of aids - Google Patents

Hiv protease inhibitors in pharmaceutical combinations for the treatment of aids Download PDF

Info

Publication number
LV13141B
LV13141B LVP-04-02A LV040002A LV13141B LV 13141 B LV13141 B LV 13141B LV 040002 A LV040002 A LV 040002A LV 13141 B LV13141 B LV 13141B
Authority
LV
Latvia
Prior art keywords
hydroxy
alkyl
compounds
hiv
optionally substituted
Prior art date
Application number
LVP-04-02A
Other languages
English (en)
Latvian (lv)
Inventor
Joseph P Vacca
Katharine M Holloway
James P Guare
Randall W Hungate
Bruce D Dorsey
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of LV13141B publication Critical patent/LV13141B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LVP-04-02A 1993-03-31 2004-01-07 Hiv protease inhibitors in pharmaceutical combinations for the treatment of aids LV13141B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4072993A 1993-03-31 1993-03-31

Publications (1)

Publication Number Publication Date
LV13141B true LV13141B (en) 2004-08-20

Family

ID=21912617

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-04-02A LV13141B (en) 1993-03-31 2004-01-07 Hiv protease inhibitors in pharmaceutical combinations for the treatment of aids

Country Status (35)

Country Link
EP (1) EP0617968B1 (xx)
JP (1) JPH08508496A (xx)
KR (1) KR100311551B1 (xx)
CN (1) CN1090186C (xx)
AT (1) ATE230610T1 (xx)
AU (1) AU685772B2 (xx)
BG (1) BG62083B1 (xx)
BR (1) BR9406503A (xx)
CA (1) CA2120192A1 (xx)
CY (1) CY2326B1 (xx)
CZ (1) CZ286412B6 (xx)
DE (1) DE69431972T2 (xx)
DK (1) DK0617968T3 (xx)
DZ (1) DZ1766A1 (xx)
ES (1) ES2188604T3 (xx)
FI (1) FI954580A (xx)
HK (1) HK1009248A1 (xx)
HR (1) HRP940209B1 (xx)
HU (1) HUT74006A (xx)
IL (1) IL109166A (xx)
LV (1) LV13141B (xx)
NO (1) NO953876L (xx)
NZ (1) NZ265164A (xx)
PL (1) PL310895A1 (xx)
PT (1) PT617968E (xx)
RO (1) RO118000B1 (xx)
RU (1) RU2139052C1 (xx)
SA (1) SA94140745B1 (xx)
SG (1) SG64366A1 (xx)
SI (1) SI9420017B (xx)
SK (1) SK279471B6 (xx)
TW (1) TW307684B (xx)
WO (1) WO1994022480A1 (xx)
YU (1) YU49275B (xx)
ZA (1) ZA942255B (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU692509B2 (en) * 1993-12-15 1998-06-11 Merck & Co., Inc. HIV protease inhibitors
UA49803C2 (uk) * 1994-06-03 2002-10-15 Дж.Д. Сьорль Енд Ко Спосіб лікування ретровірусних інфекцій
US5476874A (en) * 1994-06-22 1995-12-19 Merck & Co., Inc. New HIV protease inhibitors
WO1996012492A1 (en) * 1994-10-25 1996-05-02 Merck & Co., Inc. Microbial synthesis of hiv protease inhibitors
US6689761B1 (en) * 1995-02-01 2004-02-10 Merck & Co., Inc. Combination therapy for HIV infection
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
PE11499A1 (es) * 1997-05-16 1999-03-01 Procter & Gamble Tratamiento del hiv y cancer
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
HU9701081D0 (en) * 1997-06-23 1997-08-28 Gene Research Lab Inc N Pharmaceutical composition of antitumoral activity
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
EP1095022A1 (en) 1998-07-08 2001-05-02 G.D. Searle & Co. Retroviral protease inhibitors
WO2000021565A1 (en) * 1998-10-13 2000-04-20 Du Pont Pharmaceuticals Company Selective eradication of virally-infected cells by combined use of a cytotoxic agent and an antiviral agent
US6423734B1 (en) 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
US6407105B1 (en) 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6608096B1 (en) 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
US6462062B1 (en) 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
EP1771169A1 (en) 2004-07-14 2007-04-11 PTC Therapeutics, Inc. Methods for treating hepatitis c
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
NZ553329A (en) 2004-07-22 2010-09-30 Ptc Therapeutics Inc Thienopyridines for treating hepatitis C
RU2520967C1 (ru) * 2013-02-08 2014-06-27 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) СИММЕТРИЧНЫЕ ДИИМИНЫ НА ОСНОВЕ КАМФОРЫ - ИНГИБИТОРЫ РЕПРОДУКЦИИ ВИРУСА ГРИППА (ШТАММ A/California/07/09 (H1N1)pdm09)
CN109528747A (zh) * 2018-12-13 2019-03-29 中国人民解放军总医院 扎西他滨在制备抗菌消炎药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021647A1 (en) * 1991-06-04 1992-12-10 Smithkline Beecham Corporation Carbocyclic and heterocyclic hiv protease inhibitors

Also Published As

Publication number Publication date
CZ286412B6 (en) 2000-04-12
SK122595A3 (en) 1997-03-05
SG64366A1 (en) 1999-04-27
HU9502860D0 (en) 1995-11-28
PL310895A1 (en) 1996-01-08
PT617968E (pt) 2003-03-31
NO953876D0 (no) 1995-09-29
DE69431972D1 (de) 2003-02-13
CA2120192A1 (en) 1994-10-01
EP0617968A1 (en) 1994-10-05
AU685772B2 (en) 1998-01-29
SK279471B6 (sk) 1998-11-04
FI954580A0 (fi) 1995-09-27
CN1120316A (zh) 1996-04-10
ATE230610T1 (de) 2003-01-15
SI9420017A (en) 1996-10-31
KR960701661A (ko) 1996-03-28
DK0617968T3 (da) 2003-02-24
CZ252895A3 (en) 1996-07-17
DE69431972T2 (de) 2003-08-28
ZA942255B (en) 1994-11-01
AU5921394A (en) 1994-10-06
WO1994022480A1 (en) 1994-10-13
NO953876L (no) 1995-11-30
RO118000B1 (ro) 2002-12-30
CN1090186C (zh) 2002-09-04
SI9420017B (sl) 2003-12-31
CY2326B1 (en) 2003-11-14
IL109166A0 (en) 1994-06-24
KR100311551B1 (ko) 2001-12-28
JPH08508496A (ja) 1996-09-10
EP0617968B1 (en) 2003-01-08
SA94140745B1 (ar) 2006-07-11
TW307684B (xx) 1997-06-11
HRP940209B1 (en) 2004-04-30
BG100016A (en) 1996-04-30
NZ265164A (en) 1997-09-22
DZ1766A1 (fr) 2002-02-17
YU15994A (sh) 1999-06-15
BR9406503A (pt) 1996-01-02
YU49275B (sh) 2005-03-15
HRP940209A2 (en) 1998-02-28
BG62083B1 (bg) 1999-02-26
RU2139052C1 (ru) 1999-10-10
IL109166A (en) 1999-08-17
HK1009248A1 (en) 1999-05-28
FI954580A (fi) 1995-09-27
ES2188604T3 (es) 2003-07-01
HUT74006A (en) 1996-10-28

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