LV12734B - Use of piperazine derivatives for the treatment of cognitive disorders - Google Patents

Use of piperazine derivatives for the treatment of cognitive disorders Download PDF

Info

Publication number
LV12734B
LV12734B LVP-01-102A LV010102A LV12734B LV 12734 B LV12734 B LV 12734B LV 010102 A LV010102 A LV 010102A LV 12734 B LV12734 B LV 12734B
Authority
LV
Latvia
Prior art keywords
alkyl
aryl
cycloalkyl
hydrogen
radical
Prior art date
Application number
LVP-01-102A
Other languages
English (en)
Latvian (lv)
Other versions
LV12734A (en
Inventor
Ian Anthony Cliffe
Allan Fletcher
Alan Chapman White
Original Assignee
John Wyeth & Brothers Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth & Brothers Limited filed Critical John Wyeth & Brothers Limited
Publication of LV12734A publication Critical patent/LV12734A/xx
Publication of LV12734B publication Critical patent/LV12734B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
LVP-01-102A 1992-11-05 2001-07-04 Use of piperazine derivatives for the treatment of cognitive disorders LV12734B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929223153A GB9223153D0 (en) 1992-11-05 1992-11-05 Piperazine derivatives

Publications (2)

Publication Number Publication Date
LV12734A LV12734A (en) 2001-10-20
LV12734B true LV12734B (en) 2002-01-20

Family

ID=10724559

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-01-102A LV12734B (en) 1992-11-05 2001-07-04 Use of piperazine derivatives for the treatment of cognitive disorders

Country Status (18)

Country Link
US (1) US5827847A (cs)
EP (1) EP0877612B1 (cs)
JP (1) JP3238153B2 (cs)
AT (1) ATE195422T1 (cs)
AU (1) AU682155B2 (cs)
CA (1) CA2148593C (cs)
DE (1) DE69329252T2 (cs)
DK (1) DK0877612T3 (cs)
ES (1) ES2149216T3 (cs)
GB (1) GB9223153D0 (cs)
GR (1) GR3034400T3 (cs)
HU (1) HUT72049A (cs)
LV (1) LV12734B (cs)
MX (1) MX9306879A (cs)
PT (1) PT877612E (cs)
TW (1) TW252043B (cs)
WO (1) WO1994009780A1 (cs)
ZA (1) ZA937827B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0710481A1 (en) * 1994-11-02 1996-05-08 Duphar International Research B.V Use of flesinoxan for cognition enhancement
US6271234B1 (en) * 1997-08-01 2001-08-07 Recordati S.A., Chemical And Pharmaceutical Company 1,4-disubstituted piperazines

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2355502A1 (fr) * 1976-06-23 1978-01-20 Roussel Uclaf Application a titre de medicaments d'un derive de la piperazine et de ses sels
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
GB2222768B (en) * 1988-06-17 1992-01-22 Nat Res Dev Analgesic compounds and compositions
GB8909209D0 (en) * 1989-04-22 1989-06-07 Wyeth John & Brother Ltd Piperazine derivatives
US4902687A (en) * 1989-03-27 1990-02-20 Eli Lilly And Company Excitatory amino acid receptor antagonists
GB2230780B (en) * 1989-04-22 1992-10-21 American Home Prod Tertiary alkyl functionalized piperazine derivatives
IL94151A (en) * 1989-04-22 1995-08-31 Wyeth John & Brother Ltd History of piperazine, their preparation and pharmaceutical preparations containing them
EP0398413A1 (en) * 1989-05-16 1990-11-22 Duphar International Research B.V "3,4-dehydropiperidine derivatives having psychotropic activity
ATE178893T1 (de) * 1990-01-11 1999-04-15 Upjohn Co 6,7,8,9-tetrahydro-3h-benz(e)indolheterocyclen mit wirkung auf das zentrale nervensystem
GB9022820D0 (en) * 1990-10-19 1990-12-05 Wyeth John & Brother Ltd Piperazine derivatives
DE4039631A1 (de) * 1990-12-12 1992-06-17 Troponwerke Gmbh & Co Kg Neuroprotektive kombination
AU645681B2 (en) * 1991-05-02 1994-01-20 John Wyeth & Brother Limited Piperazine derivatives
DE4135551A1 (de) * 1991-08-31 1993-03-04 Schering Ag Verwendung von antagonisten oder partiellen agonisten am 5-ht1a-rezeptor zur behandlung und praevention von kognitiven stoerungen

Also Published As

Publication number Publication date
CA2148593A1 (en) 1994-05-11
TW252043B (cs) 1995-07-21
HUT72049A (en) 1996-03-28
AU682155B2 (en) 1997-09-25
ES2149216T3 (es) 2000-11-01
AU5342194A (en) 1994-05-24
GR3034400T3 (en) 2000-12-29
HU9501290D0 (en) 1995-06-28
GB9223153D0 (en) 1992-12-16
EP0877612B1 (en) 2000-08-16
WO1994009780A1 (en) 1994-05-11
DE69329252T2 (de) 2001-03-29
CA2148593C (en) 2005-12-06
EP0877612A1 (en) 1998-11-18
DK0877612T3 (da) 2000-10-09
ZA937827B (en) 1995-04-21
LV12734A (en) 2001-10-20
ATE195422T1 (de) 2000-09-15
JP3238153B2 (ja) 2001-12-10
PT877612E (pt) 2000-11-30
US5827847A (en) 1998-10-27
JPH08502743A (ja) 1996-03-26
MX9306879A (es) 1995-01-31
DE69329252D1 (de) 2000-09-21

Similar Documents

Publication Publication Date Title
AU703350B2 (en) Novel n-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands
RU2139867C1 (ru) Новые 4-арилпиперазины и 4-арилпиперидины, фармацевтическая композиция, способ ингибирования допамин-2-рецепторов
US6656943B2 (en) 1-phenyl-4-benzlpiperazines: dopamine receptor subtype specific ligands
FI73986C (fi) Analogifoerfarande foer framstaellning av 1-piperazinkarboxamider.
DE69219394T2 (de) Heterozyklische Alkylamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
CH616677A5 (cs)
EP0923574A1 (en) Fused indolecarboxamides: dopamine receptor subtype specific ligands
US3262852A (en) Vasodilator and anti-anginose com- pounds containing methoxy benzyl piperazines and method of using the same
CA2443636C (en) Remedial agent for chronic articular rheumatism
PL144921B1 (en) Method of obtaining novel susbtituted pyrolidinone
US4507318A (en) 1-Aryl 2-aminomethyl cyclopropane carboxylates (Z) as drugs in the treatment of pain
US3459757A (en) Imidazolidines
LV12734B (en) Use of piperazine derivatives for the treatment of cognitive disorders
US3155584A (en) Compositions and method of inhibiting monoamine oxidase and treating hypertension
GB2272155A (en) Piperazine derivatives for treatment of cognitive disorders
US3089819A (en) Method for the treatment of hypertension
US3891648A (en) 2-{8 (1,4-Benzodioxan)-2-yl{9 -acetamidines
US3320252A (en) Certain cycloalkyl benzylamines
JPH037229A (ja) 脳神経機能改善剤
WO1983001950A1 (en) 1-piperazinocarboxylates, process for their preparation and pharmaceutical compositions containing them
US3903165A (en) Ethynylaryl amines and processes for their preparation
JP3681770B2 (ja) 老年性痴呆症又はアルツハイマー病治療剤
US4289770A (en) 2-Benzoyl-4-nitroanilides and their use as medicaments
US4254131A (en) Treatment of pain, fever, and inflammation with compositions containing 2-(substitutedpiperidinomethyl)propane and propene nitriles
GB2307858A (en) Compositions containing piperazine derivatives for the treatment of cancer