LV12084B - Treatment of periodontal disease with alendronate - Google Patents

Treatment of periodontal disease with alendronate Download PDF

Info

Publication number
LV12084B
LV12084B LVP-98-43A LV980043A LV12084B LV 12084 B LV12084 B LV 12084B LV 980043 A LV980043 A LV 980043A LV 12084 B LV12084 B LV 12084B
Authority
LV
Latvia
Prior art keywords
pharmaceutically acceptable
treatment
alendronate
medicament
periodontal disease
Prior art date
Application number
LVP-98-43A
Other languages
English (en)
Latvian (lv)
Other versions
LV12084A (lv
Inventor
Barry J. GERTZ
Gideon A. Rodan
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of LV12084A publication Critical patent/LV12084A/xx
Publication of LV12084B publication Critical patent/LV12084B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LVP-98-43A 1991-12-17 1998-03-06 Treatment of periodontal disease with alendronate LV12084B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/808,701 US5270365A (en) 1991-12-17 1991-12-17 Prevention and treatment of periodontal disease with alendronate

Publications (2)

Publication Number Publication Date
LV12084A LV12084A (lv) 1998-07-20
LV12084B true LV12084B (en) 1998-11-20

Family

ID=25199466

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-98-43A LV12084B (en) 1991-12-17 1998-03-06 Treatment of periodontal disease with alendronate

Country Status (22)

Country Link
US (1) US5270365A (cs)
EP (1) EP0617624B1 (cs)
JP (1) JP2825654B2 (cs)
KR (1) KR100258667B1 (cs)
AT (1) ATE150646T1 (cs)
AU (1) AU675417B2 (cs)
CA (1) CA2122498A1 (cs)
CY (1) CY2054B1 (cs)
CZ (1) CZ282902B6 (cs)
DE (1) DE69218624T2 (cs)
DK (1) DK0617624T3 (cs)
ES (1) ES2100519T3 (cs)
GR (1) GR3022951T3 (cs)
HK (1) HK1000114A1 (cs)
HU (1) HU221807B1 (cs)
IL (1) IL104109A (cs)
LV (1) LV12084B (cs)
NO (1) NO306197B1 (cs)
NZ (1) NZ246274A (cs)
SK (1) SK280628B6 (cs)
WO (1) WO1993011774A1 (cs)
ZA (1) ZA929712B (cs)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW237386B (cs) * 1992-04-15 1995-01-01 Ciba Geigy
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
FR2703590B1 (fr) * 1993-04-05 1995-06-30 Sanofi Elf Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .
US5854227A (en) * 1994-03-04 1998-12-29 Hartmann; John F. Therapeutic derivatives of diphosphonates
JPH09511927A (ja) * 1994-04-18 1997-12-02 ザ、プロクター、エンド、ギャンブル、カンパニー 歯槽骨へのビスホスホネート類のイオン導入デリバリー
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
US5462932A (en) * 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
US5780455A (en) * 1994-08-24 1998-07-14 Merck & Co., Inc. Intravenous alendronate formulations
JP3411690B2 (ja) * 1994-09-21 2003-06-03 帝人株式会社 局所投与用アレンドロン酸ナトリウム製剤
US6008206A (en) * 1994-09-21 1999-12-28 Merck & Co., Inc. Sodium alendronate preparation for local administration
AU690431B2 (en) * 1995-02-17 1998-04-23 Merck & Co., Inc. Method of lessening the risk of non-vertebral bone fractures
US5914099A (en) * 1995-05-12 1999-06-22 Merck & Co., Inc. Prevention of tooth loss by the administration of alendronate or its salts
JP2000504718A (ja) * 1996-02-14 2000-04-18 バインダーマン，イザク 骨吸収を予防するための局所用ビスホスホネート
US6117856A (en) * 1996-02-14 2000-09-12 Binderman; Itzhak Topical bisphosphonates for prevention of bone resorption
ATE256456T1 (de) * 1996-05-17 2004-01-15 Merck & Co Inc Biphosphonat-formulierung mit brausewirkung
EP1378234A1 (en) * 1996-05-17 2004-01-07 MERCK & CO. INC. Effervescent bisphosphonate formulation
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
AU723357B2 (en) * 1996-10-04 2000-08-24 Merck & Co., Inc. Liquid alendronate formulations
US5773429A (en) * 1996-12-11 1998-06-30 Fuisz Technologies Ltd. Drug combination for treating calcium loss
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
PT998292E (pt) * 1997-07-22 2002-04-29 Merck & Co Inc Metodo para inibicao da reabsorcao ossea
US5994329A (en) 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
US6432932B1 (en) 1997-07-22 2002-08-13 Merck & Co., Inc. Method for inhibiting bone resorption
FR2784031B1 (fr) * 1998-10-02 2002-02-01 Sanofi Elf Utilisation de derives de l'acide bisphosphonique pour la preparation d'un medicament destine au traitement des boiteries
US6331533B1 (en) * 1998-11-16 2001-12-18 Merck & Co., Inc. Method for inhibiting dental resorptive lesions
PT1140113E (pt) * 1998-12-23 2004-03-31 Bioagency Ag Utilizacao de bisfosfonatos para profilaxia e tratamento de processos infecciosos
US6143919A (en) * 1999-05-18 2000-11-07 3M Innovative Properties Company Polymerizable acidic compounds and methods of preparation
US6315566B1 (en) 1999-05-18 2001-11-13 3M Innovative Properties Company Dental materials
PL196485B1 (pl) * 2000-05-11 2008-01-31 Inst Farmaceutyczny Stała doustna kompozycja farmaceutyczna zawierająca aminową pochodną kwasu bisfosfonowego i sposób jej wytwarzania
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
US20030216358A1 (en) * 2001-07-05 2003-11-20 Muchmore Douglas Boyer Method for enhancing bone mineral density gain
US20040053968A1 (en) * 2001-12-28 2004-03-18 Hartman George D. Methods and compositions for treating peridontal disease
US20070094865A1 (en) * 2002-01-10 2007-05-03 Ji-Guang Zhang Packaged thin film batteries and methods of packaging thin film batteries
US7960054B2 (en) * 2002-01-10 2011-06-14 Excellatron Solid State Llc Packaged thin film batteries
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
WO2003086415A1 (en) * 2002-04-05 2003-10-23 Merck & Co., Inc. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
FR2838339B1 (fr) * 2002-04-12 2005-06-24 Univ Angers Derives poly-phosphonates pour compositions dentifrices
US20040137058A1 (en) * 2002-07-09 2004-07-15 Katdare Ashok V. Effervescent bisphosphonate formulation
US20050142185A1 (en) * 2003-12-29 2005-06-30 Beleno Alfredo B. Softgel formulations of bisphosphonates bone resorption inhibitors
US20060034921A1 (en) * 2004-01-05 2006-02-16 Katdare Ashok V Effervescent bisphosphonate formulation
US20050181043A1 (en) * 2004-02-12 2005-08-18 Indranil Nandi Alendronate salt tablet compositions
US20080070087A1 (en) * 2004-02-20 2008-03-20 Excellatron Solid State, Llc Non-volatile cathodes for lithium oxygen batteries and method of producing same
US20050261250A1 (en) * 2004-05-19 2005-11-24 Merck & Co., Inc., Compositions and methods for inhibiting bone resorption
KR100564628B1 (ko) * 2004-06-16 2006-03-28 삼성전자주식회사 스플릿 게이트형 플래쉬 메모리 소자 및 그 제조방법
US20060134190A1 (en) * 2004-12-16 2006-06-22 Banner Pharmacaps Inc. Formulations of bisphosphonate drugs with improved bioavailability
JP2009524900A (ja) * 2005-10-11 2009-07-02 エクセラトロン ソリッド ステート，エルエルシー リチウム電池の製造方法
US20070087052A1 (en) * 2005-10-19 2007-04-19 Katdare Ashok V Effervescent bisphosphonate formulation
WO2007106742A2 (en) 2006-03-10 2007-09-20 Excellatron Solid State Llc Air battery and manufacturing method
US20090118238A1 (en) * 2007-09-17 2009-05-07 Protia, Llc Deuterium-enriched alendronate
JP2013501056A (ja) 2009-08-03 2013-01-10 キメリクス，インコーポレイテッド ウイルス感染およびウイルス誘発腫瘍を治療する組成物および方法
US8882740B2 (en) * 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone
RU2449761C1 (ru) * 2011-03-09 2012-05-10 Светлана Минифаритовна Алетдинова Способ лечения хронических апикальных периодонтитов
GB201200868D0 (en) 2012-01-19 2012-02-29 Depuy Int Ltd Bone filler composition
US9579360B2 (en) * 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis
RU2713257C1 (ru) * 2019-05-06 2020-02-04 Жанна Владимировна Вечеркина Способ лечения хронического апикального периодонтита

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3429963A (en) * 1964-06-09 1969-02-25 Colgate Palmolive Co Dental preparation containing polymeric polyelectrolyte
DE2405254C2 (de) * 1974-02-04 1982-05-27 Henkel KGaA, 4000 Düsseldorf Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper
US4134969A (en) * 1974-02-04 1979-01-16 Henkel Kommanditgesellschaft Auf Aktien (Henkel Kgaa) Method of treatment of calcium disorders using aminoalkane-diphosphonic acids
US4042679A (en) * 1975-11-07 1977-08-16 Colgate-Palmolive Company Antibacterial oral composition
US4138477A (en) * 1976-05-28 1979-02-06 Colgate Palmolive Company Composition to control mouth odor
US4440779A (en) * 1981-06-30 1984-04-03 Merck & Co., Inc. Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
US4446052A (en) * 1982-05-17 1984-05-01 The Procter & Gamble Company Aqueous gel containing tricalcium di(1-hydroxy-3-aminopropane-1,1-diphosphonate
US4639338A (en) * 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
US4677132A (en) * 1986-03-12 1987-06-30 American Home Products Corporation Inhibition of bone resorption by etodolac
ATE61371T1 (de) * 1986-11-21 1991-03-15 Ciba Geigy Ag Neue substituiertaminomethandiphosphonsaeuren.
US4871720A (en) * 1986-11-21 1989-10-03 Ciba-Geigy Corporation Aromatically substituted azacycloalkyl-alkanediphosphonic acids useful for the treatment of illnesses that can be attributed to calcium metabolism disorders
HU199151B (en) * 1987-03-10 1990-01-29 Yamanouchi Pharma Co Ltd Process for producing bis-phosphonic acid derivatives
US4816437A (en) * 1987-06-01 1989-03-28 Trustees Of Boston University Methods for inducing general and localized bone apposition in-vivo
EP0317505A1 (de) * 1987-11-13 1989-05-24 Ciba-Geigy Ag Neue Azacycloalkylalkandiphosphonsäuren
GB8726714D0 (en) * 1987-11-14 1987-12-16 Beecham Group Plc Compounds
ATE90353T1 (de) * 1987-12-11 1993-06-15 Ciba Geigy Ag Araliphatylaminoalkandiphosphonsaeuren.
US4877603A (en) * 1987-12-18 1989-10-31 The Procter & Gamble Company Oral compositions
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4990503A (en) * 1988-08-12 1991-02-05 Yamanouchi Pharmaceutical Co., Ltd. Heterocyclic bisphosphonic acid derivatives
CA2035179C (en) * 1990-01-31 2001-08-14 Gerald S. Brenner Pharmaceutical compositions containing insoluble salts of bisphosphonic acids
GB9008433D0 (en) * 1990-04-12 1990-06-13 Beecham Group Plc Novel compositions
US5019651A (en) * 1990-06-20 1991-05-28 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof

Also Published As

Publication number Publication date
HK1000114A1 (en) 1997-12-05
NO942267D0 (no) 1994-06-16
DE69218624D1 (de) 1997-04-30
JP2825654B2 (ja) 1998-11-18
JPH07502506A (ja) 1995-03-16
LV12084A (lv) 1998-07-20
EP0617624A1 (en) 1994-10-05
DK0617624T3 (da) 1997-04-21
NO942267L (no) 1994-06-16
ATE150646T1 (de) 1997-04-15
AU675417B2 (en) 1997-02-06
HU9401378D0 (en) 1994-08-29
NO306197B1 (no) 1999-10-04
ES2100519T3 (es) 1997-06-16
GR3022951T3 (en) 1997-06-30
HU221807B1 (hu) 2003-01-28
IL104109A0 (en) 1993-05-13
CZ148794A3 (en) 1995-03-15
US5270365A (en) 1993-12-14
KR940703676A (ko) 1994-12-12
HUT68788A (en) 1995-07-28
NZ246274A (en) 1997-02-24
ZA929712B (en) 1993-06-14
IL104109A (en) 1997-02-18
DE69218624T2 (de) 1997-08-07
KR100258667B1 (ko) 2000-07-01
CA2122498A1 (en) 1993-06-24
CY2054B1 (en) 1998-04-30
SK280628B6 (sk) 2000-05-16
WO1993011774A1 (en) 1993-06-24
AU3242093A (en) 1993-07-19
CZ282902B6 (cs) 1997-11-12
EP0617624B1 (en) 1997-03-26
SK72794A3 (en) 1995-04-12

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