LV11689B - 4-£(2-benzothiazolyl)methylamino|-alpha-£(3,4-difluorophenoxy)methyl|-1-piperidineethanol - Google Patents
4-£(2-benzothiazolyl)methylamino|-alpha-£(3,4-difluorophenoxy)methyl|-1-piperidineethanol Download PDFInfo
- Publication number
- LV11689B LV11689B LVP-96-334A LV960334A LV11689B LV 11689 B LV11689 B LV 11689B LV 960334 A LV960334 A LV 960334A LV 11689 B LV11689 B LV 11689B
- Authority
- LV
- Latvia
- Prior art keywords
- formula
- compound
- optionally
- inert solvent
- reaction conditions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Paper (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65964591A | 1991-02-25 | 1991-02-25 | |
| PCT/EP1992/000356 WO1992014731A1 (en) | 1991-02-25 | 1992-02-14 | 4-[(2-BENZOTHIAZOLYL)METHYLAMINO]-α-[(3,4-DIFLUOROPHENOXY)METHYL]-1-PIPERIDINEETHANOL |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LV11689A LV11689A (lv) | 1997-02-20 |
| LV11689B true LV11689B (en) | 1997-08-20 |
Family
ID=24646210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-96-334A LV11689B (en) | 1991-02-25 | 1996-08-13 | 4-£(2-benzothiazolyl)methylamino|-alpha-£(3,4-difluorophenoxy)methyl|-1-piperidineethanol |
Country Status (36)
| Country | Link |
|---|---|
| US (2) | US5434168A (cs) |
| EP (2) | EP0573473B1 (cs) |
| JP (1) | JP2825652B2 (cs) |
| KR (1) | KR0165901B1 (cs) |
| CN (3) | CN1033454C (cs) |
| AT (1) | ATE131478T1 (cs) |
| AU (1) | AU649788B2 (cs) |
| BG (1) | BG62332B1 (cs) |
| CA (1) | CA2104000A1 (cs) |
| CY (1) | CY1924A (cs) |
| CZ (1) | CZ284705B6 (cs) |
| DE (1) | DE69206787T2 (cs) |
| DK (1) | DK0573473T3 (cs) |
| DZ (1) | DZ1560A1 (cs) |
| EE (1) | EE02983B1 (cs) |
| ES (1) | ES2083737T3 (cs) |
| FI (1) | FI933719A7 (cs) |
| GR (1) | GR3018692T3 (cs) |
| HK (1) | HK172296A (cs) |
| HU (2) | HUT67695A (cs) |
| IE (1) | IE69567B1 (cs) |
| IL (3) | IL100952A (cs) |
| LV (1) | LV11689B (cs) |
| MA (1) | MA22447A1 (cs) |
| MX (1) | MX9200777A (cs) |
| NO (1) | NO300591B1 (cs) |
| NZ (2) | NZ248437A (cs) |
| PL (1) | PL168791B1 (cs) |
| RO (1) | RO112959B1 (cs) |
| RU (2) | RU2106348C1 (cs) |
| SK (1) | SK278705B6 (cs) |
| TN (1) | TNSN92017A1 (cs) |
| TW (1) | TW218016B (cs) |
| WO (1) | WO1992014731A1 (cs) |
| ZA (1) | ZA921341B (cs) |
| ZW (1) | ZW1992A1 (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZW1992A1 (en) * | 1991-02-25 | 1993-09-22 | Janssen Pharmaceutica Nv | 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol |
| TW282469B (cs) * | 1993-06-11 | 1996-08-01 | Janssen Pharmaceutica Nv | |
| MX9702506A (es) * | 1994-10-14 | 1997-07-31 | Janssen Pharmaceutica Nv | Suspensiones orales de sabeluzol. |
| JPH10509712A (ja) * | 1994-11-24 | 1998-09-22 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ルベルゾール静脈用水剤 |
| WO1996032130A1 (en) * | 1995-04-10 | 1996-10-17 | Baxter International Inc. | The use of cross-linked hemoglobin in treating subarachnoid hemorrhage |
| CA2228054A1 (en) * | 1995-10-25 | 1997-05-01 | Janssen Pharmaceutica N.V. | Lubeluzole n-oxide |
| US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
| BR9710002A (pt) * | 1996-06-27 | 1999-08-10 | Janssen Pharmaceutica Nv | N-[4-(heteroarilmetil)fenil]-heteroarilaminas |
| US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
| US6756389B2 (en) | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
| EP1037632B1 (en) * | 1997-11-10 | 2006-01-11 | Bristol-Myers Squibb Company | Benzothiazole protein tyrosine kinase inhibitors |
| GB9815785D0 (en) * | 1998-07-20 | 1998-09-16 | Cerebrus Ltd | Chemical compounds |
| AU4537500A (en) | 1999-05-12 | 2000-12-05 | Neurosearch A/S | Ion channel modulating agents |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3963732A (en) * | 1973-05-30 | 1976-06-15 | Tiberio Bruzzese | Process for preparing dihydroxydiphenylmethane derivatives |
| GB1458392A (en) * | 1973-11-09 | 1976-12-15 | Ici Ltd | Optically-active 1-aryloxy-2,3-epoxypropane derivatives |
| US4310658A (en) * | 1980-06-18 | 1982-01-12 | Allied Corporation | Production of polyester thermally stabilized with an oxirane |
| US4861785A (en) * | 1984-12-03 | 1989-08-29 | Janssen Pharmaceutica N.V. | Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents |
| CA1260474A (en) * | 1984-12-03 | 1989-09-26 | Raymond A. Stokbroekx | Benzoxazol- and benzothiazolamine derivatives |
| US4749702A (en) * | 1985-04-15 | 1988-06-07 | Janssen Pharmaceutica N. V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
| KR930005004B1 (ko) * | 1985-04-15 | 1993-06-11 | 쟈안센 파아마슈우티카 엔. 부이. | 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법 |
| US4689330A (en) * | 1985-04-15 | 1987-08-25 | Janssen Pharmaceutica N.V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
| US4717760A (en) * | 1986-07-10 | 1988-01-05 | The Dow Chemical Company | Fluorinated tris-epoxides based on triphenyl methane |
| JPH0643426B2 (ja) * | 1986-07-25 | 1994-06-08 | 東京田辺製薬株式会社 | イミダゾ〔４，５−ｂ〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤 |
| ZW1992A1 (en) * | 1991-02-25 | 1993-09-22 | Janssen Pharmaceutica Nv | 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol |
-
1992
- 1992-02-10 ZW ZW19/92A patent/ZW1992A1/xx unknown
- 1992-02-11 NZ NZ24843792A patent/NZ248437A/xx unknown
- 1992-02-11 NZ NZ24159292A patent/NZ241592A/en unknown
- 1992-02-12 CN CN92101908A patent/CN1033454C/zh not_active Expired - Fee Related
- 1992-02-14 AT AT92905117T patent/ATE131478T1/de not_active IP Right Cessation
- 1992-02-14 PL PL92300354A patent/PL168791B1/pl unknown
- 1992-02-14 CA CA002104000A patent/CA2104000A1/en not_active Abandoned
- 1992-02-14 HU HU9302395A patent/HUT67695A/hu unknown
- 1992-02-14 RO RO93-01147A patent/RO112959B1/ro unknown
- 1992-02-14 AU AU12085/92A patent/AU649788B2/en not_active Ceased
- 1992-02-14 DE DE69206787T patent/DE69206787T2/de not_active Expired - Fee Related
- 1992-02-14 FI FI933719A patent/FI933719A7/fi unknown
- 1992-02-14 RU RU95112519/04A patent/RU2106348C1/ru not_active IP Right Cessation
- 1992-02-14 ES ES92905117T patent/ES2083737T3/es not_active Expired - Lifetime
- 1992-02-14 EP EP92905117A patent/EP0573473B1/en not_active Expired - Lifetime
- 1992-02-14 RU RU9293053624A patent/RU2094434C1/ru active
- 1992-02-14 IL IL10095292A patent/IL100952A/en not_active IP Right Cessation
- 1992-02-14 US US08/098,297 patent/US5434168A/en not_active Expired - Fee Related
- 1992-02-14 WO PCT/EP1992/000356 patent/WO1992014731A1/en active IP Right Grant
- 1992-02-14 DK DK92905117.5T patent/DK0573473T3/da active
- 1992-02-14 EP EP92200417A patent/EP0501552A1/en active Pending
- 1992-02-14 IL IL11383792A patent/IL113837A/en active IP Right Grant
- 1992-02-14 JP JP4504615A patent/JP2825652B2/ja not_active Expired - Fee Related
- 1992-02-20 TW TW081101226A patent/TW218016B/zh active
- 1992-02-21 CZ CS92512A patent/CZ284705B6/cs not_active IP Right Cessation
- 1992-02-21 SK SK512-92A patent/SK278705B6/sk unknown
- 1992-02-21 MA MA22735A patent/MA22447A1/fr unknown
- 1992-02-24 DZ DZ920018A patent/DZ1560A1/fr active
- 1992-02-24 ZA ZA921341A patent/ZA921341B/xx unknown
- 1992-02-24 IE IE920575A patent/IE69567B1/en not_active IP Right Cessation
- 1992-02-24 MX MX9200777A patent/MX9200777A/es not_active IP Right Cessation
- 1992-02-25 TN TNTNSN92017A patent/TNSN92017A1/fr unknown
-
1993
- 1993-08-23 KR KR1019930702525A patent/KR0165901B1/ko not_active Expired - Fee Related
- 1993-08-24 BG BG98068A patent/BG62332B1/bg unknown
- 1993-08-24 NO NO933010A patent/NO300591B1/no unknown
-
1994
- 1994-11-21 EE EE9400339A patent/EE02983B1/xx unknown
-
1995
- 1995-03-24 US US08/410,549 patent/US5675027A/en not_active Expired - Fee Related
- 1995-05-24 IL IL11383795A patent/IL113837A0/xx unknown
- 1995-05-30 CN CN95105633A patent/CN1117048A/zh active Pending
- 1995-05-30 CN CN95105632A patent/CN1043609C/zh not_active Expired - Fee Related
- 1995-06-21 HU HU95P/P00319P patent/HU211560A9/hu unknown
-
1996
- 1996-01-17 GR GR960400093T patent/GR3018692T3/el unknown
- 1996-08-13 LV LVP-96-334A patent/LV11689B/en unknown
- 1996-09-12 HK HK172296A patent/HK172296A/en not_active IP Right Cessation
-
1997
- 1997-03-07 CY CY192497A patent/CY1924A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11939292B1 (en) | Aza-substituted psilocin analogs and methods of synthesizing the same | |
| EP2049518B1 (en) | Indazole and isoindole derivatives as glucokinase activating agents. | |
| US9815832B2 (en) | Azabenzimidazole compounds | |
| US11932617B2 (en) | Compound for use in retinal diseases | |
| EP0232937B1 (en) | Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines | |
| LV11689B (en) | 4-£(2-benzothiazolyl)methylamino|-alpha-£(3,4-difluorophenoxy)methyl|-1-piperidineethanol | |
| US11629136B1 (en) | Substituted pyridine derivatives as SARM1 inhibitors | |
| CZ580390A3 (en) | 6-ARYL-5,6-DIHYDRO-IMIDAZO£2,1-b|THIAZOLE DERIVATIVES, PROCESS OF THEIR PREPARATION, INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | |
| US5530011A (en) | 4-[(2-benzothiazolyl)methylamino]-α-[(3,4-difluorophenoxy)methyl]-1-piperidineethanol | |
| WO2023219789A1 (en) | Novel psilocin prodrug compounds and methods of synthesizing the same | |
| US12064415B2 (en) | Psilocin prodrug compounds and methods of synthesizing the same | |
| US20240217949A1 (en) | Compound for use in retinal diseases | |
| CN109280028B (zh) | 喹啉类化合物及其在dpp-4酶抑制剂的应用 | |
| KR20240046553A (ko) | Sting 길항제로서의 소분자 우레아 유도체 | |
| TW202310830A (zh) | 用於治療疾病之β-內醯胺衍生物 |