LV10504B - Microbiological process for hydroxylation of heterocyclic carboxylic acid - Google Patents

Microbiological process for hydroxylation of heterocyclic carboxylic acid

Info

Publication number
LV10504B
LV10504B LVP-93-162A LV930162A LV10504B LV 10504 B LV10504 B LV 10504B LV 930162 A LV930162 A LV 930162A LV 10504 B LV10504 B LV 10504B
Authority
LV
Latvia
Prior art keywords
hydroxylation
carboxylic acid
microbiological process
heterocyclic carboxylic
nitrogen
Prior art date
Application number
LVP-93-162A
Other languages
English (en)
Other versions
LV10504A (lv
Inventor
Kiener Andreas
Tschech Andreas
Tinschert Andreas
Heinzmann Klaus
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of LV10504A publication Critical patent/LV10504A/xx
Publication of LV10504B publication Critical patent/LV10504B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
LVP-93-162A 1992-03-04 1993-03-02 Microbiological process for hydroxylation of heterocyclic carboxylic acid LV10504B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH67292 1992-03-04

Publications (2)

Publication Number Publication Date
LV10504A LV10504A (lv) 1995-02-20
LV10504B true LV10504B (en) 1996-02-20

Family

ID=4192473

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-162A LV10504B (en) 1992-03-04 1993-03-02 Microbiological process for hydroxylation of heterocyclic carboxylic acid

Country Status (17)

Country Link
US (2) US5306630A (cs)
EP (1) EP0559116B1 (cs)
JP (1) JPH06199797A (cs)
KR (1) KR100274205B1 (cs)
CN (1) CN1077748A (cs)
AT (1) ATE153698T1 (cs)
CA (1) CA2091005C (cs)
CZ (1) CZ282939B6 (cs)
DE (1) DE59306547D1 (cs)
DK (1) DK0559116T3 (cs)
ES (1) ES2101887T3 (cs)
GE (1) GEP19991710B (cs)
GR (1) GR3024286T3 (cs)
LT (1) LT3114B (cs)
LV (1) LV10504B (cs)
RU (1) RU2122029C1 (cs)
SK (1) SK279322B6 (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9426293D0 (en) * 1994-12-28 1995-02-22 Zeneca Ltd Composition,compound and use
US5763232A (en) * 1996-02-15 1998-06-09 Mitsubishi Chemical Corporation Method for producing 3-hydroxy nitrogen-containing six-membered cylic compound
US6767741B1 (en) * 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
EP1210410B1 (en) * 1999-08-27 2008-01-16 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
AU2002220603A1 (en) * 2000-10-06 2002-04-15 Lonza A.G. Biotechnological method for preparing carboxylic acids with a hydroxy-nitrogen heterocycle
WO2009041473A1 (ja) * 2007-09-27 2009-04-02 Toyama Chemical Co., Ltd. ６－フルオロ－３－ヒドロキシ－２－ピラジンカルボニトリルの有機アミン塩およびその製造法
MX2013005179A (es) * 2010-11-12 2013-07-05 Fujifilm Corp Derivado de pirazino[2,3-d]isoxazol.
KR102848894B1 (ko) * 2022-10-26 2025-08-21 한국원자력연구원 합성 니코틴의 감별 방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4081451A (en) * 1975-03-20 1978-03-28 Schering Corporation Process for preparing 2-halogeno nicotinic acids
JPS6061567A (ja) * 1983-09-14 1985-04-09 ロンザ　リミテツド ２−ピリジンカルボン酸−ν−オキサイドから２−ヒドロキシピリジンを製造する方法
CH658866A5 (de) * 1984-02-21 1986-12-15 Lonza Ag Verfahren zur herstellung von 6-hydroxynikotinsaeure.
CH658867A5 (de) * 1984-02-22 1986-12-15 Lonza Ag Verfahren zur herstellung von 6-hydroxynikotinsaeure.
IN170700B (cs) * 1989-12-20 1992-05-02 Lonza Ag
US5236832A (en) * 1990-02-13 1993-08-17 Lonza, Ltd. Microbiological oxidation of methyl groups in heterocycles
US5242816A (en) * 1990-07-10 1993-09-07 Lonza Ltd. Microbiological oxidation of alkyl groups in heterocycles
CZ279464B6 (cs) * 1990-09-24 1995-05-17 Lonza A.G. Způsob hydroxylace methylových skupin v aromatických heterocyklech, hybridní plasmidy pL05 a p L04 uložené v mikroorganismech Pseudomonas putida a Escherichia coli
CZ279488B6 (cs) * 1990-09-25 1995-05-17 Lonza A.G. Způsob mikrobiologické výroby hydroxylovaných heterocyklů
KR100233330B1 (ko) * 1991-02-04 1999-12-01 하인즈 모제르 6-히드록시피콜린산을 제조하기 위한 미생물학적 방법
US5238830A (en) * 1991-02-04 1993-08-24 Lonza Ltd. Microbiological process for the production of 6-hydroxypicolinic acid
JPH0728750B2 (ja) * 1991-03-30 1995-04-05 池田食研株式会社 微生物によるピラジン酸の水酸化物の製造方法
JPH0740951B2 (ja) * 1991-03-30 1995-05-10 池田食研株式会社 微生物による含窒素複素環化合物の水酸化物の製造方法
FI922125A7 (fi) * 1991-06-21 1992-12-22 Lonza Ag Mikrobiologinen menetelmä 5-hydroksipyratsiinikarboksyylihapon valmistamiseksi
MX9204902A (es) * 1991-08-30 1993-05-01 Lonza Ag Procedimiento microbiologico para la preparacion de acido 6-hidroxipirazincarboxilico.

Also Published As

Publication number Publication date
GEP19991710B (en) 1999-08-05
US5306630A (en) 1994-04-26
GR3024286T3 (en) 1997-10-31
US5364940A (en) 1994-11-15
DK0559116T3 (da) 1997-06-16
LT3114B (en) 1994-12-27
KR930019834A (ko) 1993-10-19
EP0559116B1 (de) 1997-05-28
CZ282939B6 (cs) 1997-11-12
LV10504A (lv) 1995-02-20
KR100274205B1 (ko) 2000-12-15
ATE153698T1 (de) 1997-06-15
CA2091005C (en) 2001-09-25
SK279322B6 (sk) 1998-10-07
EP0559116A3 (en) 1994-07-06
CA2091005A1 (en) 1993-09-05
ES2101887T3 (es) 1997-07-16
DE59306547D1 (de) 1997-07-03
CN1077748A (zh) 1993-10-27
CZ27293A3 (en) 1994-01-19
EP0559116A2 (de) 1993-09-08
JPH06199797A (ja) 1994-07-19
LTIP377A (en) 1994-06-15
RU2122029C1 (ru) 1998-11-20
SK13793A3 (en) 1993-10-06

Similar Documents

Publication Publication Date Title
IL105980A (en) Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals
HUP0100394A2 (hu) 2-es Helyzetben fenil-szubsztituenst hordozó imidazo-triazinon-származékok, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények
AU589427B2 (en) Pyridonecarboxylic acid derivatives and process for their preparation
EP0320118A3 (en) Peptides with collagenase inhibiting activity
HUT34976A (en) Process for production of new 1,8 naftiridine derivates and medical preparates consisting of such compounds as reagents
ES8403905A1 (es) Procedimiento para la preparacion de nuevos derivados piperidinicos, piperacinicos y homopiperacinicos.
HU9301155D0 (en) Methods for producing steroide derivatives and for their application in medical treatment
LV10504B (en) Microbiological process for hydroxylation of heterocyclic carboxylic acid
AU626095B2 (en) Hydroxyalkane carboxylic acid derivatives, their production and use
AU1572188A (en) Process for the preparation of quinoline carboxylic acids
IE882552L (en) Novel benzimidazole derivatives
CA2131474A1 (en) Preparation of hydroxyoxaalkylmelamines
IL111829A (en) PROCESS FOR PREPARING IMIDAZO £4, 5-b| PYRIDINE DERIVATIVES
MX9702089A (es) Carboxamidas biciclicas como antagonistas de 5-ht1a.
MX9700003A (es) Proceso para la reparacion de derivados de ??cido-clorometil-fenilglioxilico.
TW358087B (en) Method for preparing carbamoylmethylurea derivatives
ES449446A1 (es) Un procedimiento para la produccion de acidos 1-oxo-1h-6-pi-peridinogicamente activos y esteres de los mismos.
CA2364862A1 (en) Process for preparing derivatives of biphenyl-2-carboxylic acid
TW430652B (en) Process for preparing 2-phenyl-3-naphthyl propionic acid derivatives
ES8606368A1 (es) Un procedimiento para producir un derivado de bencil-fosfi- nato etilico
GR880100409A (en) Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids
HRP940443B1 (en) Process for the preparation of 1-nitro-2,2-diaminoethylene derivatives
MX9705275A (es) Procedimiento para la obtencion de n-aril y n-hetarilhidroxilaminas.