GR880100409A - Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids - Google Patents

Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids

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Publication number
GR880100409A
GR880100409A GR88100409A GR880100409A GR880100409A GR 880100409 A GR880100409 A GR 880100409A GR 88100409 A GR88100409 A GR 88100409A GR 880100409 A GR880100409 A GR 880100409A GR 880100409 A GR880100409 A GR 880100409A
Authority
GR
Greece
Prior art keywords
cyclopropyl
dihydro
oxo
fluoro
quinoline
Prior art date
Application number
GR88100409A
Other languages
Greek (el)
Other versions
GR1000201B (en
Inventor
Kleon Tsetis
Original Assignee
Kleon Tsetis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kleon Tsetis filed Critical Kleon Tsetis
Publication of GR880100409A publication Critical patent/GR880100409A/en
Publication of GR1000201B publication Critical patent/GR1000201B/en

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Abstract

A method of preparation is described for 1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7-chloro-kinolin-3-carboxylic acid: [chemical formula] as well as the reaction process of the acid (I) with piperazine, or its derivatives of the formula: [chemical formula], where R = methyl, ethyl, benzyl, pyridyl, hydrogen. Transformations of these new piperazinic derivatives to acidic additive salts are distinguished for their antibacterial properties and are pharmaceutically useful.
GR880100409A 1988-06-23 1988-06-23 Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids GR1000201B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR88100409 1988-06-23

Publications (2)

Publication Number Publication Date
GR880100409A true GR880100409A (en) 1990-05-11
GR1000201B GR1000201B (en) 1992-03-20

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ID=10938767

Family Applications (1)

Application Number Title Priority Date Filing Date
GR880100409A GR1000201B (en) 1988-06-23 1988-06-23 Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids

Country Status (1)

Country Link
GR (1) GR1000201B (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078362A2 (en) * 1981-10-29 1983-05-11 Bayer Ag 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-quinoline-3-carboxylic acids, process for their preparation and antibacterial agents containing them
EP0113091A1 (en) * 1982-12-29 1984-07-11 Bayer Ag Microbiocidal agents based on quinolone-carboxylic acids
ES8602674A1 (en) * 1985-02-07 1985-12-01 Inst Investigacion Desarrollo Quinoline carboxylic acid derivs.
ES8606284A1 (en) * 1985-10-30 1986-04-16 Lafarquim Prepn. of quinoline-3-carboxylic acid and salts

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078362A2 (en) * 1981-10-29 1983-05-11 Bayer Ag 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-quinoline-3-carboxylic acids, process for their preparation and antibacterial agents containing them
EP0113091A1 (en) * 1982-12-29 1984-07-11 Bayer Ag Microbiocidal agents based on quinolone-carboxylic acids
ES8602674A1 (en) * 1985-02-07 1985-12-01 Inst Investigacion Desarrollo Quinoline carboxylic acid derivs.
ES8606284A1 (en) * 1985-10-30 1986-04-16 Lafarquim Prepn. of quinoline-3-carboxylic acid and salts

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 105, 1986, page 774, abstract no. 226392c, Columbus Ohio, US; & ES-A1-8602674 (INSTITUTO DE INVESTIGACION Y DESARROLLO QUIMICO Y BIOLOGICO S.A.) 16-03-1986 *
CHEMICAL ABSTRACTS, vol. 107, 1987, page 708, abstract no. 39864n, Columbus, Ohio, US; & ES-A1-8606284 (LABORATORIO FARMACEUTICO QUIMICO-LAFARQUIM S.A.) 01-10-1986 *
CLAIMS SEARCHED: ALL *

Also Published As

Publication number Publication date
GR1000201B (en) 1992-03-20

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