GEP19970816B - Process for producing quinolinecarboxylic acid derivatives - Google Patents

Process for producing quinolinecarboxylic acid derivatives

Info

Publication number
GEP19970816B
GEP19970816B GEAP19931333A GEAP1993001333A GEP19970816B GE P19970816 B GEP19970816 B GE P19970816B GE AP19931333 A GEAP19931333 A GE AP19931333A GE AP1993001333 A GEAP1993001333 A GE AP1993001333A GE P19970816 B GEP19970816 B GE P19970816B
Authority
GE
Georgia
Prior art keywords
general formula
salt
compound
piperazinyl
compounds
Prior art date
Application number
GEAP19931333A
Inventor
Peter Ritli
Maria Balogh
Agnes Horvath
Dr Debreczy Lelle Vasvarine
Geza Kereszturi
Istvan Hermecz
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to GEAP19931333A priority Critical patent/GEP19970816B/en
Publication of GEP19970816B publication Critical patent/GEP19970816B/en

Links

Abstract

The invention relates to a new process for the preparation of compounds of general formula (I), (wherein R stands for piperazinyl, 4-methyl-piperazinyl or 4-ethyl-piperazinyl group) and pharmaceutically acceptable salts thereof which comprises reacting a compound of general formula (II), (wherein R<1> and R<2> stand for halogen, for an aliphatic acyloxy group containing 2 to 6 carbon atoms and optionally substituted by halogen, or for an aromatic acyloxy group containing 7 to 11 carbon atoms) with a piperazine derivative of general formula (III), (wherein R<3> stands for hydrogen, methyl or ethyl) or a salt thereof and subjecting the compound of general formula (IV) thus obtained, (wherein R, R<1> and R<2> are as stated above) to hydrolysis after or without isolation and if desired converting the compound of general formula (I); thus obtained into a salt thereof or setting free the same from its salt. The compounds of general formula (I) are known antibacterial agents. The advantage of the present invention is that it makes the desired compounds of general formula (I) available in a simple manner, with high yields and in a short reaction time.
GEAP19931333A 1993-07-31 1993-07-31 Process for producing quinolinecarboxylic acid derivatives GEP19970816B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GEAP19931333A GEP19970816B (en) 1993-07-31 1993-07-31 Process for producing quinolinecarboxylic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GEAP19931333A GEP19970816B (en) 1993-07-31 1993-07-31 Process for producing quinolinecarboxylic acid derivatives

Publications (1)

Publication Number Publication Date
GEP19970816B true GEP19970816B (en) 1997-01-30

Family

ID=82484112

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP19931333A GEP19970816B (en) 1993-07-31 1993-07-31 Process for producing quinolinecarboxylic acid derivatives

Country Status (1)

Country Link
GE (1) GEP19970816B (en)

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