ES8606284A1 - Prepn. of quinoline-3-carboxylic acid and salts - Google Patents
Prepn. of quinoline-3-carboxylic acid and saltsInfo
- Publication number
- ES8606284A1 ES8606284A1 ES548375A ES548375A ES8606284A1 ES 8606284 A1 ES8606284 A1 ES 8606284A1 ES 548375 A ES548375 A ES 548375A ES 548375 A ES548375 A ES 548375A ES 8606284 A1 ES8606284 A1 ES 8606284A1
- Authority
- ES
- Spain
- Prior art keywords
- salts
- prepn
- quinoline
- carboxylic acid
- cpd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Pref. comprises (a) reacting cpd. (II) with bromo-cyclopropane in presence of K2CO3 in dimethyl formaldehyde under reflux for 8-24 hrs. to give cpd. (III), (b) hydrolysing (III) in basic medium (NaOH/AlH) under reflux to give cpd. (I) and its pharmaceutically acceptable salts.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES548375A ES8606284A1 (en) | 1985-10-30 | 1985-10-30 | Prepn. of quinoline-3-carboxylic acid and salts |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES548375A ES8606284A1 (en) | 1985-10-30 | 1985-10-30 | Prepn. of quinoline-3-carboxylic acid and salts |
Publications (2)
Publication Number | Publication Date |
---|---|
ES548375A0 ES548375A0 (en) | 1986-04-16 |
ES8606284A1 true ES8606284A1 (en) | 1986-04-16 |
Family
ID=8490065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES548375A Expired ES8606284A1 (en) | 1985-10-30 | 1985-10-30 | Prepn. of quinoline-3-carboxylic acid and salts |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8606284A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR880100409A (en) * | 1988-06-23 | 1990-05-11 | Kleon Tsetis | Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids |
-
1985
- 1985-10-30 ES ES548375A patent/ES8606284A1/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR880100409A (en) * | 1988-06-23 | 1990-05-11 | Kleon Tsetis | Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids |
Also Published As
Publication number | Publication date |
---|---|
ES548375A0 (en) | 1986-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970401 |