ES8606284A1 - Prepn. of quinoline-3-carboxylic acid and salts - Google Patents

Prepn. of quinoline-3-carboxylic acid and salts

Info

Publication number
ES8606284A1
ES8606284A1 ES548375A ES548375A ES8606284A1 ES 8606284 A1 ES8606284 A1 ES 8606284A1 ES 548375 A ES548375 A ES 548375A ES 548375 A ES548375 A ES 548375A ES 8606284 A1 ES8606284 A1 ES 8606284A1
Authority
ES
Spain
Prior art keywords
salts
prepn
quinoline
carboxylic acid
cpd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548375A
Other languages
Spanish (es)
Other versions
ES548375A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Farmaceutico Quimico Lafarquim SA
Original Assignee
Laboratorio Farmaceutico Quimico Lafarquim SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Farmaceutico Quimico Lafarquim SA filed Critical Laboratorio Farmaceutico Quimico Lafarquim SA
Priority to ES548375A priority Critical patent/ES8606284A1/en
Publication of ES548375A0 publication Critical patent/ES548375A0/en
Publication of ES8606284A1 publication Critical patent/ES8606284A1/en
Expired legal-status Critical Current

Links

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  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Pref. comprises (a) reacting cpd. (II) with bromo-cyclopropane in presence of K2CO3 in dimethyl formaldehyde under reflux for 8-24 hrs. to give cpd. (III), (b) hydrolysing (III) in basic medium (NaOH/AlH) under reflux to give cpd. (I) and its pharmaceutically acceptable salts.
ES548375A 1985-10-30 1985-10-30 Prepn. of quinoline-3-carboxylic acid and salts Expired ES8606284A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES548375A ES8606284A1 (en) 1985-10-30 1985-10-30 Prepn. of quinoline-3-carboxylic acid and salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES548375A ES8606284A1 (en) 1985-10-30 1985-10-30 Prepn. of quinoline-3-carboxylic acid and salts

Publications (2)

Publication Number Publication Date
ES548375A0 ES548375A0 (en) 1986-04-16
ES8606284A1 true ES8606284A1 (en) 1986-04-16

Family

ID=8490065

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548375A Expired ES8606284A1 (en) 1985-10-30 1985-10-30 Prepn. of quinoline-3-carboxylic acid and salts

Country Status (1)

Country Link
ES (1) ES8606284A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR880100409A (en) * 1988-06-23 1990-05-11 Kleon Tsetis Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR880100409A (en) * 1988-06-23 1990-05-11 Kleon Tsetis Method for the synthesis of 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-chloro-quinoline-3-carboxylic acid as basis for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-quinoline-3-carboxylic acids

Also Published As

Publication number Publication date
ES548375A0 (en) 1986-04-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401