LU92565I9 - - Google Patents
Info
- Publication number
- LU92565I9 LU92565I9 LU92565C LU92565C LU92565I9 LU 92565 I9 LU92565 I9 LU 92565I9 LU 92565 C LU92565 C LU 92565C LU 92565 C LU92565 C LU 92565C LU 92565 I9 LU92565 I9 LU 92565I9
- Authority
- LU
- Luxembourg
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/452—Piperidinium derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56562304P | 2004-04-27 | 2004-04-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
LU92565I2 LU92565I2 (fr) | 2014-12-02 |
LU92565I9 true LU92565I9 (enEXAMPLES) | 2019-01-17 |
Family
ID=35242158
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LU92565C LU92565I2 (fr) | 2004-04-27 | 2014-10-02 | Bromure d'umeclidinum |
Country Status (38)
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20050250A1 (es) * | 2003-07-17 | 2005-04-08 | Glaxo Group Ltd | Antagonistas de los receptores muscarinicos de la acetilcolina |
AR046114A1 (es) * | 2003-10-17 | 2005-11-23 | Glaxo Group Ltd | Compuesto de 8- azoniabiciclo (3.2.1) octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos y uso del compuesto para preparar dicha composicion |
AR046225A1 (es) * | 2003-11-04 | 2005-11-30 | Glaxo Group Ltd | Compuesto de 8-azoniabiciclo(3.2.1)octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos que lo comprende y uso del compuesto para preparar dicha composicion |
JP2007528420A (ja) * | 2004-03-11 | 2007-10-11 | グラクソ グループ リミテッド | 新規m3ムスカリン性アセチルコリン受容体アンタゴニスト |
EP1725564A4 (en) * | 2004-03-17 | 2007-09-12 | Glaxo Group Ltd | ANTAGONISTS OF THE M3 MUSCARIN ACETYL CHOLIN RECEPTOR |
US20070185148A1 (en) * | 2004-03-17 | 2007-08-09 | Glaxo Group Limited | M3 muscarinic acetylchoine receptor antagonists |
EP1732547B1 (en) * | 2004-04-05 | 2008-08-20 | Samaritan Pharmaceuticals, Inc. | Anti-hiv quinuclidine compounds |
AR050902A1 (es) | 2004-04-27 | 2006-12-06 | Glaxo Group Ltd | Compuesto de quinuclidina, composicion farmaceutica que lo comprende y su usopara preparar dicha composicion |
US7598267B2 (en) * | 2004-05-13 | 2009-10-06 | Glaxo Group Limited | Muscarinic acetylcholine receptor antagonists |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
JP2008520579A (ja) * | 2004-11-15 | 2008-06-19 | グラクソ グループ リミテッド | 新規m3ムスカリン性アセチルコリン受容体アンタゴニスト |
JP2009503099A (ja) * | 2005-08-02 | 2009-01-29 | グラクソ グループ リミテッド | M3ムスカリン性アセチルコリン受容体アンタゴニスト |
JP2009504768A (ja) * | 2005-08-18 | 2009-02-05 | グラクソ グループ リミテッド | ムスカリン性アセチルコリン受容体アンタゴニスト |
US7943651B2 (en) | 2006-04-20 | 2011-05-17 | Glaxo Group Limited | Compounds |
GB0611587D0 (en) | 2006-06-12 | 2006-07-19 | Glaxo Group Ltd | Novel compounds |
PL2046787T3 (pl) | 2006-08-01 | 2011-10-31 | Glaxo Group Ltd | Związki pirazolo[3,4-b]pirydynowe i ich zastosowanie jako inhibitory PDE4 |
PE20081889A1 (es) | 2007-03-23 | 2009-03-05 | Smithkline Beecham Corp | Indol carboxamidas como inhibidores de ikk2 |
PE20091563A1 (es) | 2008-02-06 | 2009-11-05 | Glaxo Group Ltd | Farmacoforos duales - antagonistas muscarinicos de pde4 |
AR070562A1 (es) | 2008-02-06 | 2010-04-21 | Glaxo Group Ltd | Farmacoforos duales - antagonistas muscarinicos de pde4 |
TW200946526A (en) | 2008-02-06 | 2009-11-16 | Glaxo Group Ltd | Dual pharmacophores-PDE4-muscarinic antagonistics |
US8163743B2 (en) | 2008-06-05 | 2012-04-24 | GlaxoGroupLimited | 4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases |
EP2280959B1 (en) | 2008-06-05 | 2012-04-04 | Glaxo Group Limited | 4-amino-indazoles |
WO2010094643A1 (en) | 2009-02-17 | 2010-08-26 | Glaxo Group Limited | Quinoline derivatives and their uses for rhinitis and urticaria |
US11116721B2 (en) | 2009-02-26 | 2021-09-14 | Glaxo Group Limited | Pharmaceutical formulations comprising 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl) phenol |
WO2010102958A1 (en) | 2009-03-09 | 2010-09-16 | Glaxo Group Limited | 4-oxadiazol-2 -yl- indazoles as inhibitors of p13 kinases |
EP2406249A1 (en) | 2009-03-10 | 2012-01-18 | Glaxo Group Limited | Indole derivatives as ikk2 inhibitors |
WO2010106016A1 (en) | 2009-03-17 | 2010-09-23 | Glaxo Group Limited | Pyrimidine derivatives used as itk inhibitors |
US20120046286A1 (en) | 2009-04-30 | 2012-02-23 | Julie Nicole Hamblin | Novel Compounds |
WO2011029896A1 (en) | 2009-09-11 | 2011-03-17 | Glaxo Group Limited | Methods of preparation of muscarinic acetylcholine receptor antagonists |
GB0921075D0 (en) | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
US20120245171A1 (en) | 2009-12-03 | 2012-09-27 | Glaxo Group Limited | Benzpyrazole derivatives as inhibitors of pi3 kinases |
EP2507226A1 (en) | 2009-12-03 | 2012-10-10 | Glaxo Group Limited | Novel compounds |
WO2011067366A1 (en) | 2009-12-03 | 2011-06-09 | Glaxo Group Limited | Indazole derivatives as pi 3 - kinase inhibitors |
MX2012008703A (es) * | 2010-01-28 | 2012-11-12 | Theron Pharmaceuticals Inc | Derivados de 7-azoniabiciclo [2.2.1] heptano, sus metodos de produccion y usos farmaceuticos. |
WO2011110575A1 (en) | 2010-03-11 | 2011-09-15 | Glaxo Group Limited | Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases |
MA34326B1 (fr) * | 2010-06-22 | 2013-06-01 | Chiesi Farma Spa | Formulation de poudre sèche comprenant un médicament antimuscarinique |
DK2614058T3 (en) | 2010-09-08 | 2015-09-28 | Glaxosmithkline Ip Dev Ltd | Polymorphs, and the salts of N- [5- [4- (5 - {[(2R, 6S) -2,6-dimethyl-4-morpholinyl] methyl} -1,3-oxazol-2-yl) -1H-indazole -6-yl] -2- (methyloxy) -3-pyridinyl] methanesulfonamide. |
WO2012035055A1 (en) | 2010-09-17 | 2012-03-22 | Glaxo Group Limited | Novel compounds |
GB201018124D0 (en) | 2010-10-27 | 2010-12-08 | Glaxo Group Ltd | Polymorphs and salts |
RU2013153202A (ru) | 2011-06-08 | 2015-07-20 | Глаксо Груп Лимитед | Композиции для ингалятора сухого порошка, содержащие умеклидиний |
EA201391618A1 (ru) * | 2011-06-08 | 2014-05-30 | Глаксо Груп Лимитед | Комбинация, содержащая умеклидиний и кортикостероид |
AU2013246926B2 (en) | 2012-04-13 | 2016-07-21 | Glaxosmithkline Intellectual Property Development Limited | Aggregate particles |
RU2502743C1 (ru) * | 2012-08-03 | 2013-12-27 | Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения и социального развития РФ (ФГБУ "РКНПК" Минздравсоцразвития России) | Синтетический антиген, обладающий способностью связывать аутоантитела к мускариновому м2-рецептору |
BR112015003101B1 (pt) * | 2012-08-15 | 2022-06-14 | Glaxo Group Limited | Processo para a preparação de um composto |
GB201222679D0 (en) | 2012-12-17 | 2013-01-30 | Glaxo Group Ltd | Pharmaceutical combination products |
US9751875B2 (en) * | 2013-07-13 | 2017-09-05 | Beijing Fswelcome Technology Development Co., Ltd. | Quinine compounds, and optical isomers, preparation method and medical use thereof |
WO2015015446A1 (en) * | 2013-07-30 | 2015-02-05 | Glaxosmithkline Intellectual Property Development Limited | Topical compositions for treatment of excessive sweating and methods of use thereof |
KR20160062178A (ko) | 2013-10-17 | 2016-06-01 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 호흡기 질병의 치료를 위한 pi3k 억제제 |
JP2016537327A (ja) | 2013-10-17 | 2016-12-01 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 呼吸器疾患の治療のためのpi3k阻害剤 |
CR20160529A (es) | 2014-05-12 | 2017-01-02 | Glaxosmithkline Intellectual Property (No 2) Ltd | Composiciones farmacéuticas para tratar enfermedades infecciosas |
US10987363B2 (en) | 2014-05-28 | 2021-04-27 | Glaxosmithkline Intellectual Property Development Limited | Fluticasone furoate in the treatment of COPD |
WO2016071792A1 (en) | 2014-11-03 | 2016-05-12 | Laboratorio Chimico Internazionale S.P.A. | Method for the preparation of 1-(2-halogen-ethyl)-4 piperidine-carboxylic acid ethyl esters |
KR101613245B1 (ko) | 2015-04-27 | 2016-04-18 | 주식회사 대웅제약 | 신규의 4-메톡시 피롤 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
CN105461710A (zh) * | 2015-10-23 | 2016-04-06 | 安徽德信佳生物医药有限公司 | 一种芜地溴铵的制备方法 |
CA3008292A1 (en) * | 2016-01-08 | 2017-07-13 | Theron Pharmaceuticals, Inc. | Dry powder inhaler compositions of 7-azoniabicyclo[2.2.1]heptane derivatives |
GB201602527D0 (en) | 2016-02-12 | 2016-03-30 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
CN107200734B (zh) * | 2016-03-18 | 2019-12-24 | 益方生物科技(上海)有限公司 | 奎宁环衍生物及其制备方法和用途 |
EP3248970A1 (en) | 2016-05-27 | 2017-11-29 | Zentiva K.S. | Forms of umeclidinium bromide |
JP2019524792A (ja) | 2016-08-08 | 2019-09-05 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 化合物 |
PT109740B (pt) * | 2016-11-14 | 2020-07-30 | Hovione Farmaciencia Sa | Processo para a preparação de brometo de umeclidínio |
WO2018163212A1 (en) * | 2017-03-08 | 2018-09-13 | Gbr Laboratories Pvt. Ltd | A process for the preparation of umeclidinium bromide and intermediates thereof |
GB201706102D0 (en) | 2017-04-18 | 2017-05-31 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
IT201700058796A1 (it) | 2017-05-30 | 2018-11-30 | Olon Spa | Procedimento per la preparazione di un nuovo intermedio di sintesi dell’umeclidinio. |
GB201712081D0 (en) | 2017-07-27 | 2017-09-13 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
CN111511800B (zh) | 2017-10-30 | 2023-11-28 | 武田药品工业株式会社 | 灭活脂包膜病毒的环境相容性去污剂 |
CN108558860B (zh) * | 2018-06-04 | 2020-12-25 | 成都伊诺达博医药科技有限公司 | 一种合成芜地溴铵的方法 |
WO2020047225A1 (en) | 2018-08-30 | 2020-03-05 | Theravance Biopharma R&D Ip, Llc | Methods for treating chronic obstructive pulmonary disease |
PT115583B (pt) | 2019-06-17 | 2022-05-02 | Hovione Farm S A | Processo contínuo para a preparação de medicamentos anticolinérgicos |
CN113387923A (zh) * | 2020-03-13 | 2021-09-14 | 诺华股份有限公司 | 硫辛酸胆碱酯盐的药物组合物及使用其的治疗方法 |
CA3173172A1 (en) | 2020-03-26 | 2021-09-30 | Christopher D. Kane | Cathepsin inhibitors for preventing or treating viral infections |
CN111484445B (zh) * | 2020-04-21 | 2021-05-18 | 广东莱佛士制药技术有限公司 | 分离纯化高纯度乌美溴铵的中间体的方法 |
CA3181333A1 (en) * | 2020-04-26 | 2021-11-04 | Beijing Showby Pharmaceutical Co., Ltd. | Crystals, preparation method and application of a muscarinic receptor antagonist |
JP2023541601A (ja) | 2020-09-10 | 2023-10-03 | プレシリックス・ナームローゼ・ベンノートシヤープ | Fapに対する抗体フラグメント |
CN112479983B (zh) * | 2020-11-25 | 2022-07-12 | 江苏豪森药业集团有限公司 | 乌美溴铵中间体及其制备方法 |
PT117440B (pt) | 2021-09-03 | 2024-04-26 | Hovione Farm S A | Processo para a preparação de aminas cíclicas cloroaquilo substituídas |
WO2023203135A1 (en) | 2022-04-22 | 2023-10-26 | Precirix N.V. | Improved radiolabelled antibody |
JP2025517625A (ja) | 2022-05-02 | 2025-06-10 | プレシリックス・ナームローゼ・ベンノートシヤープ | プレターゲティング |
WO2024251812A1 (en) | 2023-06-07 | 2024-12-12 | Pharmazell Gmbh | A process for the preparation of umeclidinium bromide intermediate |
Family Cites Families (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2800481A (en) * | 1955-07-01 | 1957-07-23 | Smith Kline French Lab | Tertiary alcohol derivatives of 8-alkylnortropanes and the acid and quaternary ammonium salts thereof |
US2800478A (en) * | 1955-07-01 | 1957-07-23 | Smith Kline French Lab | 3-substituted-8-alkylnortropanes and the acid and quaternary ammonium salts thereof |
AT298118B (de) | 1967-06-08 | 1972-04-25 | Siemens Ag | Verfahren zur Umsetzung von Spannungen in digitale Werte und Vorrichtung zur Durchführung des Verfahrens |
GB1242211A (en) | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
GB1230087A (enEXAMPLES) | 1967-08-17 | 1971-04-28 | ||
GB1381872A (en) | 1971-06-22 | 1975-01-29 | Fisons Ltd | Pharmaceutical compositions for inhalation |
GB2064336B (en) | 1979-12-06 | 1984-03-14 | Glaxo Group Ltd | Device for dispensing medicaments |
CY1492A (en) | 1981-07-08 | 1990-02-16 | Draco Ab | Powder inhalator |
IL69932A (en) | 1982-10-08 | 1987-12-31 | Glaxo Group Ltd | Devices for administering medicaments to patients |
GB2169265B (en) | 1982-10-08 | 1987-08-12 | Glaxo Group Ltd | Pack for medicament |
IE59026B1 (en) | 1985-07-30 | 1993-12-15 | Glaxo Group Ltd | Devices for administering medicaments to patients |
IT1204826B (it) | 1986-03-04 | 1989-03-10 | Chiesi Farma Spa | Composizioni farmaceutiche per inalazione |
GB9004781D0 (en) | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
US5780466A (en) | 1995-01-30 | 1998-07-14 | Sanofi | Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present |
US6350758B1 (en) | 1996-12-02 | 2002-02-26 | Georgetown University | Tropane derivatives and method for their synthesis |
US6248752B1 (en) | 1998-02-27 | 2001-06-19 | Charles Duane Smith | Azabicyclooctane compositions and methods for enhancing chemotherapy |
US6262066B1 (en) | 1998-07-27 | 2001-07-17 | Schering Corporation | High affinity ligands for nociceptin receptor ORL-1 |
ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
SK287414B6 (sk) * | 2000-12-28 | 2010-09-07 | Laboratorios Almirall, S.A. | Chinuklidínové deriváty a kompozície s ich obsahom |
CA2462980A1 (en) | 2001-10-17 | 2003-04-24 | Ucb, S.A. | Quinuclidine derivatives, processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors |
EP1442037A1 (en) * | 2001-11-09 | 2004-08-04 | PHARMACIA & UPJOHN COMPANY | Azabicyclic-phenyl-fused-heterocyclic compounds and their use as alpha7 nachr ligands |
UA76571C2 (en) * | 2001-12-20 | 2006-08-15 | Derivatives of 1-alkyl-1-azoniabicyclo [2.2.2.]octanecarbamate and use thereof as antagonists of muscarin receptor | |
US6696462B2 (en) * | 2002-01-31 | 2004-02-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anticholinergics, processes for the preparation thereof, and pharmaceutical compositions |
ES2206021B1 (es) | 2002-04-16 | 2005-08-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de pirrolidinio. |
ES2204295B1 (es) * | 2002-07-02 | 2005-08-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de quinuclidina-amida. |
PE20040892A1 (es) | 2002-08-06 | 2004-11-19 | Glaxo Group Ltd | Antagonistas del receptor muscarinico m3 de acetilcolina |
US7232841B2 (en) | 2003-04-07 | 2007-06-19 | Glaxo Group Limited | M3 muscarinic acetylcholine receptor antagonists |
PE20050711A1 (es) | 2003-07-17 | 2005-09-10 | Glaxo Group Ltd | Compuestos 8-azoniabiciclo[3.2.1] octanos como antagonistas de los receptores muscarinicos de la acetilcolina |
PE20050250A1 (es) * | 2003-07-17 | 2005-04-08 | Glaxo Group Ltd | Antagonistas de los receptores muscarinicos de la acetilcolina |
TW200523261A (en) | 2003-07-17 | 2005-07-16 | Glaxo Group Ltd | Muscarinic acetylcholine receptor antagonists |
CN101230061A (zh) | 2003-10-14 | 2008-07-30 | 葛兰素集团有限公司 | 蕈毒碱性乙酰胆碱受体拮抗剂 |
AR046114A1 (es) | 2003-10-17 | 2005-11-23 | Glaxo Group Ltd | Compuesto de 8- azoniabiciclo (3.2.1) octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos y uso del compuesto para preparar dicha composicion |
AR046225A1 (es) | 2003-11-04 | 2005-11-30 | Glaxo Group Ltd | Compuesto de 8-azoniabiciclo(3.2.1)octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos que lo comprende y uso del compuesto para preparar dicha composicion |
ES2329586T3 (es) | 2003-11-21 | 2009-11-27 | Theravance, Inc. | Compuestos que tienen actividad agonista del receptor beta2 adrenergico y antagonista del receptor muscarino. |
UY28645A1 (es) | 2003-12-03 | 2005-06-30 | Glaxo Group Ltd | Nuevos antagonistas del receptor muscarinico m3 de acetilcolina |
PE20050861A1 (es) | 2003-12-03 | 2005-12-10 | Glaxo Group Ltd | Derivados de sales ciclicas de amonio cuaternario como antagonistas del receptor muscarinico de acetilcolina |
TW200534855A (en) | 2004-01-13 | 2005-11-01 | Glaxo Group Ltd | Muscarinic acetylcholine receptor antagonists |
JP2007528420A (ja) | 2004-03-11 | 2007-10-11 | グラクソ グループ リミテッド | 新規m3ムスカリン性アセチルコリン受容体アンタゴニスト |
JP2007530451A (ja) | 2004-03-11 | 2007-11-01 | グラクソ グループ リミテッド | 新規m3ムスカリン性アセチルコリン受容体アンタゴニスト |
US20070185148A1 (en) | 2004-03-17 | 2007-08-09 | Glaxo Group Limited | M3 muscarinic acetylchoine receptor antagonists |
EP1725564A4 (en) | 2004-03-17 | 2007-09-12 | Glaxo Group Ltd | ANTAGONISTS OF THE M3 MUSCARIN ACETYL CHOLIN RECEPTOR |
WO2005094834A1 (en) | 2004-03-17 | 2005-10-13 | Glaxo Group Limited | Muscarinic acetylcholine receptor antagonists |
US20070185088A1 (en) | 2004-03-17 | 2007-08-09 | Jakob Busch-Petersen | M3 muscarinic acetylchoine receptor antagonists |
EP1732923A2 (en) | 2004-04-07 | 2006-12-20 | Glaxo Group Limited | Muscarinic acetylcholine receptor antagonists |
AR050902A1 (es) * | 2004-04-27 | 2006-12-06 | Glaxo Group Ltd | Compuesto de quinuclidina, composicion farmaceutica que lo comprende y su usopara preparar dicha composicion |
US7598267B2 (en) | 2004-05-13 | 2009-10-06 | Glaxo Group Limited | Muscarinic acetylcholine receptor antagonists |
EP1749012A4 (en) | 2004-05-28 | 2009-07-29 | Glaxo Group Ltd | ANTAGONISTS OF MUSCARIN ACETYLCHOLIN RECEPTOR |
EP1765339A4 (en) | 2004-06-30 | 2009-09-02 | Glaxo Group Ltd | ANTAGONISTS OF MUSCARIN ACETYLCHOLIN RECEPTOR |
EP1781104A4 (en) | 2004-08-05 | 2008-05-21 | Glaxo Group Ltd | ANTAGONISTS OF THE ACETYLCHOLINE MUSCARINIC RECEPTOR |
JP2008509158A (ja) | 2004-08-06 | 2008-03-27 | グラクソ グループ リミテッド | ムスカリン性アセチルコリン受容体アンタゴニスト |
US20090258858A1 (en) | 2004-10-29 | 2009-10-15 | Jakob Busch-Petersen | Muscarinic acetylcholine receptor antagonists |
EP1827439A4 (en) | 2004-11-15 | 2009-11-18 | Glaxo Group Ltd | NEW M3 MUSCARIN ACETYLCHOLINE RECEPTOR ANTAGONISTS |
JP2008520579A (ja) | 2004-11-15 | 2008-06-19 | グラクソ グループ リミテッド | 新規m3ムスカリン性アセチルコリン受容体アンタゴニスト |
PE20060826A1 (es) | 2004-12-06 | 2006-10-08 | Smithkline Beecham Corp | Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende |
PE20061162A1 (es) | 2004-12-06 | 2006-10-14 | Smithkline Beecham Corp | Compuestos derivados olefinicos de 8-azoniabiciclo[3.2.1]octanos |
WO2006065788A2 (en) | 2004-12-13 | 2006-06-22 | Glaxo Group Limited | Novel muscarinic acetylcholine receptor antagonists |
WO2006065755A2 (en) | 2004-12-13 | 2006-06-22 | Glaxo Group Limited | Quaternary ammonium salts of fused hetearomatic amines as novel muscarinic acetylcholine receptor antagonists |
WO2007018514A1 (en) | 2005-07-28 | 2007-02-15 | Glaxo Group Limited | Novel m3 muscarinic acetylcholine receptor antagonists |
WO2007018508A1 (en) | 2005-07-28 | 2007-02-15 | Glaxo Group Limited | Novel m3 muscarinic acetycholine receptor antagonists |
WO2007016650A2 (en) | 2005-08-02 | 2007-02-08 | Glaxo Group Limited | M3 muscarinic acetylcholine receptor antagonists |
JP2009503099A (ja) | 2005-08-02 | 2009-01-29 | グラクソ グループ リミテッド | M3ムスカリン性アセチルコリン受容体アンタゴニスト |
JP2009504768A (ja) | 2005-08-18 | 2009-02-05 | グラクソ グループ リミテッド | ムスカリン性アセチルコリン受容体アンタゴニスト |
GB0921075D0 (en) * | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
-
2005
- 2005-04-25 AR ARP050101627A patent/AR050902A1/es active IP Right Grant
- 2005-04-25 TW TW094113034A patent/TWI363759B/zh active
- 2005-04-25 PE PE2005000457A patent/PE20060259A1/es active IP Right Grant
- 2005-04-25 MY MYPI20051806A patent/MY144753A/en unknown
- 2005-04-25 UY UY28871A patent/UY28871A1/es not_active Application Discontinuation
- 2005-04-27 US US11/568,330 patent/US7498440B2/en not_active Expired - Lifetime
- 2005-04-27 AP AP2006003746A patent/AP2213A/xx active
- 2005-04-27 ES ES05746609.6T patent/ES2392848T4/es not_active Expired - Lifetime
- 2005-04-27 PL PL05746609T patent/PL1740177T3/pl unknown
- 2005-04-27 CA CA2755954A patent/CA2755954C/en not_active Expired - Lifetime
- 2005-04-27 HU HUE12170402A patent/HUE031304T2/hu unknown
- 2005-04-27 BR BRPI0510170A patent/BRPI0510170B8/pt active IP Right Grant
- 2005-04-27 EP EP12170402.7A patent/EP2570128B1/en not_active Expired - Lifetime
- 2005-04-27 WO PCT/US2005/014386 patent/WO2005104745A2/en active Application Filing
- 2005-04-27 PT PT121704027T patent/PT2570128T/pt unknown
- 2005-04-27 JP JP2007510915A patent/JP5014121B2/ja not_active Expired - Lifetime
- 2005-04-27 EP EP05746609A patent/EP1740177B1/en not_active Expired - Lifetime
- 2005-04-27 HR HRP20120832TT patent/HRP20120832T1/hr unknown
- 2005-04-27 CN CN2010105580787A patent/CN102040602A/zh active Pending
- 2005-04-27 CA CA2564742A patent/CA2564742C/en not_active Expired - Lifetime
- 2005-04-27 AU AU2005237576A patent/AU2005237576B2/en active Active
- 2005-04-27 NZ NZ549997A patent/NZ549997A/en not_active IP Right Cessation
- 2005-04-27 SI SI200531605T patent/SI1740177T1/sl unknown
- 2005-04-27 MX MXPA06012405A patent/MXPA06012405A/es active IP Right Grant
- 2005-04-27 PT PT05746609T patent/PT1740177E/pt unknown
- 2005-04-27 SG SG2012087052A patent/SG186597A1/en unknown
- 2005-04-27 CN CNA2005800215360A patent/CN1976701A/zh active Pending
- 2005-04-27 EA EA201100019A patent/EA021994B1/ru not_active IP Right Cessation
- 2005-04-27 KR KR1020117001909A patent/KR101152032B1/ko not_active Expired - Lifetime
- 2005-04-27 UA UAA200611253A patent/UA95768C2/ru unknown
- 2005-04-27 ES ES12170402.7T patent/ES2600405T3/es not_active Expired - Lifetime
- 2005-04-27 SI SI200532099A patent/SI2570128T1/sl unknown
- 2005-04-27 KR KR1020067022276A patent/KR101037026B1/ko not_active Expired - Lifetime
- 2005-04-27 DK DK05746609.6T patent/DK1740177T3/da active
- 2005-04-27 EA EA200601991A patent/EA015033B1/ru not_active IP Right Cessation
- 2005-04-27 LT LTEP12170402.7T patent/LT2570128T/lt unknown
- 2005-04-27 DK DK12170402.7T patent/DK2570128T3/en active
- 2005-04-27 EP EP16177012.8A patent/EP3111936A1/en not_active Withdrawn
- 2005-04-27 PL PL12170402T patent/PL2570128T3/pl unknown
-
2006
- 2006-09-18 IL IL178152A patent/IL178152A/en active Protection Beyond IP Right Term
- 2006-10-13 ZA ZA2006/08565A patent/ZA200608565B/en unknown
- 2006-10-20 EC EC2006006940A patent/ECSP066940A/es unknown
- 2006-10-31 MA MA29426A patent/MA28631B1/fr unknown
- 2006-11-24 NO NO20065417A patent/NO338959B1/no active Protection Beyond IP Right Term
-
2007
- 2007-07-09 US US11/774,867 patent/US7488827B2/en active Active
-
2009
- 2009-01-14 US US12/353,436 patent/US8183257B2/en not_active Expired - Lifetime
-
2012
- 2012-02-22 US US13/401,890 patent/US8309572B2/en not_active Expired - Lifetime
- 2012-04-13 JP JP2012092339A patent/JP5398871B2/ja not_active Expired - Lifetime
- 2012-09-26 US US13/627,007 patent/US8575347B2/en not_active Expired - Lifetime
- 2012-10-17 CY CY20121100965T patent/CY1113196T1/el unknown
-
2013
- 2013-10-14 US US14/052,816 patent/US8853404B2/en not_active Expired - Lifetime
-
2014
- 2014-09-04 US US14/476,940 patent/US9045469B2/en not_active Expired - Lifetime
- 2014-09-26 HU HUS1400053C patent/HUS1400053I1/hu unknown
- 2014-10-02 NL NL300694C patent/NL300694I1/nl unknown
- 2014-10-02 LU LU92565C patent/LU92565I2/xx unknown
- 2014-10-02 FR FR14C0075C patent/FR14C0075I2/fr active Active
- 2014-10-02 BE BE2014C063C patent/BE2014C063I2/fr unknown
- 2014-10-03 CY CY2014043C patent/CY2014043I2/el unknown
-
2015
- 2015-05-08 US US14/707,543 patent/US9144571B2/en not_active Expired - Lifetime
- 2015-09-10 US US14/849,775 patent/US20160002220A1/en not_active Abandoned
-
2016
- 2016-10-10 CY CY20161101008T patent/CY1118082T1/el unknown
- 2016-10-25 HR HRP20161385TT patent/HRP20161385T1/hr unknown
-
2017
- 2017-05-04 NO NO2017018C patent/NO2017018I2/no unknown
- 2017-05-04 NO NO2017017C patent/NO2017017I1/no unknown