LU84291A1 - Compositions pharmaceutiques a inhaler - Google Patents

Compositions pharmaceutiques a inhaler Download PDF

Info

Publication number
LU84291A1
LU84291A1 LU84291A LU84291A LU84291A1 LU 84291 A1 LU84291 A1 LU 84291A1 LU 84291 A LU84291 A LU 84291A LU 84291 A LU84291 A LU 84291A LU 84291 A1 LU84291 A1 LU 84291A1
Authority
LU
Luxembourg
Prior art keywords
particles
medicament
diameter
drug
sodium cromoglycate
Prior art date
Application number
LU84291A
Other languages
English (en)
French (fr)
Inventor
Raymond Brian Forrester
Terence David Boardman
Original Assignee
Fisons Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10523464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU84291(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fisons Plc filed Critical Fisons Plc
Publication of LU84291A1 publication Critical patent/LU84291A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU84291A 1981-07-24 1982-07-23 Compositions pharmaceutiques a inhaler LU84291A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8122846 1981-07-24
GB8122846 1981-07-24

Publications (1)

Publication Number Publication Date
LU84291A1 true LU84291A1 (fr) 1983-02-07

Family

ID=10523464

Family Applications (1)

Application Number Title Priority Date Filing Date
LU84291A LU84291A1 (fr) 1981-07-24 1982-07-23 Compositions pharmaceutiques a inhaler

Country Status (26)

Country Link
US (1) US4590206A (ja)
EP (1) EP0072046B1 (ja)
JP (1) JPS5859914A (ja)
KR (1) KR890002908B1 (ja)
AU (1) AU540826B2 (ja)
BE (1) BE893912A (ja)
CA (1) CA1187415A (ja)
CH (1) CH657273A5 (ja)
DE (1) DE3268533D1 (ja)
DK (1) DK159716C (ja)
FI (1) FI822548L (ja)
FR (1) FR2510405B1 (ja)
GR (1) GR76229B (ja)
HK (1) HK10088A (ja)
HU (1) HU196904B (ja)
IE (1) IE53640B1 (ja)
IL (1) IL66375A0 (ja)
LU (1) LU84291A1 (ja)
MA (1) MA19548A1 (ja)
MY (1) MY8700857A (ja)
NO (1) NO156394C (ja)
NZ (1) NZ201341A (ja)
PH (1) PH22759A (ja)
PT (1) PT75310B (ja)
SG (1) SG68487G (ja)
ZA (1) ZA825222B (ja)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260306A (en) * 1981-07-24 1993-11-09 Fisons Plc Inhalation pharmaceuticals
US5204113A (en) * 1987-04-09 1993-04-20 Fisons Plc Pharmaceutical compositions containing pentamidine
ATE77947T1 (de) * 1987-04-09 1992-07-15 Fisons Plc Pentamidin enthaltende pharmazeutische zusammensetzungen.
US5776434A (en) 1988-12-06 1998-07-07 Riker Laboratories, Inc. Medicinal aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5198221A (en) * 1989-05-17 1993-03-30 Fisons Plc Pharmaceutical composition
US5439670A (en) * 1989-11-28 1995-08-08 Riker Laboratories, Inc. Medicinal aerosol formulations
US5376386A (en) * 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
EP0465841A3 (en) * 1990-06-13 1992-10-14 Hoechst Aktiengesellschaft Quick acting pharmaceutical inhalation forms of diuretics
US5228607A (en) * 1991-06-07 1993-07-20 Tvp, Inc. Rack mountable on a trailer hitch ball
ES2177544T3 (es) * 1992-06-12 2002-12-16 Teijin Ltd Polvo ultrafinno para inhalar y metodo para su preparacion.
US6509006B1 (en) * 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
KR100291620B1 (ko) * 1992-09-29 2001-10-24 추후제출 부갑상선호르몬의활성단편의폐를통한전달방법
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
EG20677A (en) * 1993-10-01 1999-11-30 Astra Ag Method and an apparatus for micronizing the particle size
IS1736B (is) * 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
CZ295827B6 (cs) 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
ATE299892T1 (de) * 1994-05-18 2005-08-15 Nektar Therapeutics Methoden und zusammensetzungen für die trockenpuderarznei aus interferonen
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
SE9700136D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700134D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5612053A (en) * 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
EP0843565A4 (en) * 1995-05-12 2002-10-16 Genentech Inc ADMINISTRATION OF AN AEROSOL CONTAINING COARSE PARTICLES FOR BIOLOGICAL USE
GB9606677D0 (en) * 1996-03-29 1996-06-05 Glaxo Wellcome Inc Process and device
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US6254854B1 (en) 1996-05-24 2001-07-03 The Penn Research Foundation Porous particles for deep lung delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
USRE37053E1 (en) 1996-05-24 2001-02-13 Massachusetts Institute Of Technology Particles incorporating surfactants for pulmonary drug delivery
US6503480B1 (en) 1997-05-23 2003-01-07 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
AU6014098A (en) * 1996-12-31 1998-07-31 Inhale Therapeutic Systems Aerosolized hydrophobic drug
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US20020017295A1 (en) * 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
US6946117B1 (en) * 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
CA2304819C (en) * 1997-09-29 2008-04-08 Inhale Therapeutic Systems, Inc. Perforated microparticles and methods of use
JP2002509119A (ja) * 1998-01-13 2002-03-26 アストラゼネカ ユーケイ リミテッド ドーパミン（Ｄ２）レセプターアゴニスト活性を有する化合物およびβ２−アドレナリンレセプターアゴニスト活性を有する化合物（Ｂ）を含有する薬学的組成物
WO1999054376A1 (fr) * 1998-04-20 1999-10-28 Cosmo Research Institute Polyester et procede de production de celui-ci
US6451349B1 (en) 1998-08-19 2002-09-17 Quadrant Healthcare (Uk) Limited Spray-drying process for the preparation of microparticles
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US6858199B1 (en) * 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
WO2001013891A2 (en) * 1999-08-25 2001-03-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
AU3400501A (en) 2000-02-28 2001-09-12 Vectura Ltd Improvements in or relating to the delivery of oral drugs
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
AU2001277230A1 (en) * 2000-08-01 2002-02-13 Inhale Therapeutic Systems, Inc. Apparatus and process to produce particles having a narrow size distribution andparticles made thereby
SE0002822L (sv) * 2000-08-04 2002-01-29 Microdrug Ag Elektropulver
FI20002215A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
AU2002230993B2 (en) 2000-12-29 2006-02-02 Alkermes, Inc. Particles for inhalation having sustained release properties
US20030125236A1 (en) * 2000-12-29 2003-07-03 Advenced Inhalation Research, Inc. Particles for inhalation having rapid release properties
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
DE10128779A1 (de) † 2001-06-13 2003-01-02 Boehringer Ingelheim Pharma Verfahren zur Reinigung von Hartgelatinekapseln
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
WO2003020197A1 (en) 2001-09-05 2003-03-13 Vectura Limited Improvements in or relating to the delivery of oral drugs
EP1446104B2 (en) 2001-11-01 2011-08-03 Novartis AG Spray drying methods
DK1455755T3 (da) * 2001-11-20 2013-07-15 Civitas Therapeutics Inc Forbedrede partikelsammensætning til levering i lunge
WO2003043603A1 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Particulate compositions for improving solubility of poorly soluble agents
SI1458360T1 (sl) 2001-12-19 2011-08-31 Novartis Ag Pulmonalno dajanje aminoglikozidov
US20040014679A1 (en) * 2002-02-20 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co., Kg Inhalation powder containing the CGRP antagonist BIBN4096 and process for the preparation thereof
EP1490031A1 (en) * 2002-03-07 2004-12-29 Vectura Limited Fast melt multiparticulate formulations for oral delivery
US7582284B2 (en) * 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
WO2003094890A1 (en) * 2002-05-07 2003-11-20 Nektar Therapeutics Capsules for dry powder inhalers and methods of making and using same
MXPA05007154A (es) 2002-12-30 2005-09-21 Nektar Therapeutics Atomizador prepeliculizacion.
AU2004272077A1 (en) * 2003-09-10 2005-03-24 Map Pharmaceuticals, Inc. Aerosol formulations for delivery of dihydroergotamine to the systemic circulation via pulmonary inhalation
WO2006078841A1 (en) * 2005-01-21 2006-07-27 President And Fellows Of Harvard College Systems and methods for forming fluidic droplets encapsulated in particles such as colloidal particles
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
PL2425820T3 (pl) 2007-02-11 2015-08-31 Map Pharmaceuticals Inc Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych
US20110171141A1 (en) * 2009-06-26 2011-07-14 Kellerman Donald J Administration of dihydroergotamine mesylate particles using a metered dose inhaler
TW201131615A (en) 2009-12-09 2011-09-16 Asahi Glass Co Ltd Multilayer mirror for euv lithography and process for producing same
US9808030B2 (en) 2011-02-11 2017-11-07 Grain Processing Corporation Salt composition
KR20140147891A (ko) 2012-04-13 2014-12-30 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 응집체 입자
RU2696582C2 (ru) * 2013-03-15 2019-08-05 Перл Терапьютикс, Инк. Способы и системы кондиционирования дисперсных кристаллических материалов

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1569611A (en) * 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
GB1520248A (en) * 1975-07-24 1978-08-02 Fisons Ltd Sodium cromoglycate containing medicament
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
IE45260B1 (en) * 1976-01-23 1982-07-28 Fisons Ltd Pelletised or granular medicament formulation
GB1549229A (en) * 1976-09-23 1979-08-01 Fisons Ltd High density sodium cromoglycate

Also Published As

Publication number Publication date
HK10088A (en) 1988-02-12
NO822556L (no) 1983-01-25
SG68487G (en) 1988-02-19
US4590206A (en) 1986-05-20
JPH0468285B2 (ja) 1992-11-02
EP0072046B1 (en) 1986-01-15
BE893912A (fr) 1983-01-24
DK325982A (da) 1983-01-25
PT75310B (en) 1985-11-29
MY8700857A (en) 1987-12-31
GR76229B (ja) 1984-08-04
IE53640B1 (en) 1989-01-04
NO156394B (no) 1987-06-09
HU196904B (en) 1989-02-28
DE3268533D1 (en) 1986-02-27
KR840000226A (ko) 1984-02-18
EP0072046A1 (en) 1983-02-16
FI822548A0 (fi) 1982-07-20
MA19548A1 (fr) 1983-04-01
FR2510405B1 (fr) 1985-07-26
NO156394C (no) 1987-09-16
FI822548L (fi) 1983-01-25
FR2510405A1 (fr) 1983-02-04
AU540826B2 (en) 1984-12-06
CH657273A5 (fr) 1986-08-29
DK159716B (da) 1990-11-26
PH22759A (en) 1988-12-12
ZA825222B (en) 1983-05-25
NZ201341A (en) 1985-05-31
IL66375A0 (en) 1982-11-30
AU8635582A (en) 1983-02-10
KR890002908B1 (ko) 1989-08-11
JPS5859914A (ja) 1983-04-09
IE821770L (en) 1983-01-24
PT75310A (en) 1982-08-01
DK159716C (da) 1991-04-29
CA1187415A (en) 1985-05-21

Similar Documents

Publication Publication Date Title
LU84291A1 (fr) Compositions pharmaceutiques a inhaler
US6221338B1 (en) Method of producing particles for use in dry powder inhalers
US4161516A (en) Composition for treating airway disease
US5260306A (en) Inhalation pharmaceuticals
AU635616B2 (en) Aerosol carriers
FI65547B (fi) Foerfarande foer framstaellning av foer inhalering avsedda mjuka dinatriumkromoglykatpelletar
KR102337781B1 (ko) 폐용 초저밀도 분말
GB2105189A (en) Inhalation drugs
FI110162B (fi) Menetelmä farmaseuttisten inhalaatiokoostumusten valmistamiseksi
US10813881B2 (en) Dry powder inhalation device
WO2003077886A1 (fr) Procede de fabrication de particules composites contenant un produit chimique
GB1569611A (en) Pelletised or granular medicament formulation
CA2670155C (en) Stable powder formulation containing an anticholinergic agent
FI116657B (fi) Menetelmä kantoainehiukkasten käsittelemiseksi ja niiden käyttö
US20100047359A1 (en) Stable powder formulation containing a novel anticholinergic agent
FR2647115A1 (fr) Composition pharmaceutique de nedocromil sodique
FI67663B (fi) Foerfarande foer framstaellning av ihalerbara mjuka dinatriumkromoglykatgranulater
WO2002100378A2 (en) Process for the preparation of a particulate material
WO2017146994A1 (en) Controlled agglomeration of micronized drug or drug-excipient mixtures
CA1144862A (en) Composition
RU2634258C1 (ru) Наполнитель для капсульного ингалятора
JPH0142950B2 (ja)