FR2510405B1 - Composition pharmaceutique a inhaler - Google Patents

Composition pharmaceutique a inhaler

Info

Publication number
FR2510405B1
FR2510405B1 FR828212902A FR8212902A FR2510405B1 FR 2510405 B1 FR2510405 B1 FR 2510405B1 FR 828212902 A FR828212902 A FR 828212902A FR 8212902 A FR8212902 A FR 8212902A FR 2510405 B1 FR2510405 B1 FR 2510405B1
Authority
FR
France
Prior art keywords
inhaled
pharmaceutical composition
pharmaceutical
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR828212902A
Other languages
English (en)
Other versions
FR2510405A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10523464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2510405(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of FR2510405A1 publication Critical patent/FR2510405A1/fr
Application granted granted Critical
Publication of FR2510405B1 publication Critical patent/FR2510405B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR828212902A 1981-07-24 1982-07-23 Composition pharmaceutique a inhaler Expired FR2510405B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8122846 1981-07-24

Publications (2)

Publication Number Publication Date
FR2510405A1 FR2510405A1 (fr) 1983-02-04
FR2510405B1 true FR2510405B1 (fr) 1985-07-26

Family

ID=10523464

Family Applications (1)

Application Number Title Priority Date Filing Date
FR828212902A Expired FR2510405B1 (fr) 1981-07-24 1982-07-23 Composition pharmaceutique a inhaler

Country Status (26)

Country Link
US (1) US4590206A (fr)
EP (1) EP0072046B1 (fr)
JP (1) JPS5859914A (fr)
KR (1) KR890002908B1 (fr)
AU (1) AU540826B2 (fr)
BE (1) BE893912A (fr)
CA (1) CA1187415A (fr)
CH (1) CH657273A5 (fr)
DE (1) DE3268533D1 (fr)
DK (1) DK159716C (fr)
FI (1) FI822548L (fr)
FR (1) FR2510405B1 (fr)
GR (1) GR76229B (fr)
HK (1) HK10088A (fr)
HU (1) HU196904B (fr)
IE (1) IE53640B1 (fr)
IL (1) IL66375A0 (fr)
LU (1) LU84291A1 (fr)
MA (1) MA19548A1 (fr)
MY (1) MY8700857A (fr)
NO (1) NO156394C (fr)
NZ (1) NZ201341A (fr)
PH (1) PH22759A (fr)
PT (1) PT75310B (fr)
SG (1) SG68487G (fr)
ZA (1) ZA825222B (fr)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260306A (en) * 1981-07-24 1993-11-09 Fisons Plc Inhalation pharmaceuticals
WO1988007855A1 (fr) * 1987-04-09 1988-10-20 Fisons Plc Compositions pharmaceutiques contenant de la pentamidine
US5204113A (en) * 1987-04-09 1993-04-20 Fisons Plc Pharmaceutical compositions containing pentamidine
US5776434A (en) * 1988-12-06 1998-07-07 Riker Laboratories, Inc. Medicinal aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5198221A (en) * 1989-05-17 1993-03-30 Fisons Plc Pharmaceutical composition
US5439670A (en) * 1989-11-28 1995-08-08 Riker Laboratories, Inc. Medicinal aerosol formulations
US5376386A (en) * 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
EP0465841A3 (en) * 1990-06-13 1992-10-14 Hoechst Aktiengesellschaft Quick acting pharmaceutical inhalation forms of diuretics
US5228607A (en) * 1991-06-07 1993-07-20 Tvp, Inc. Rack mountable on a trailer hitch ball
CA2115065C (fr) * 1992-06-12 2000-10-03 Kiyoyuki Sakon Poudre particulaire ultrafine pour inhalation et methode de production
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) * 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
KR100291620B1 (ko) * 1992-09-29 2001-10-24 추후제출 부갑상선호르몬의활성단편의폐를통한전달방법
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
WO1995009615A1 (fr) * 1993-10-01 1995-04-13 Astra Aktiebolag Procede (i)
IS1736B (is) 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
KR100419037B1 (ko) 1994-03-07 2004-06-12 넥타르 테라퓨틱스 폐를통한인슐린의전달방법및그조성물
CN1073119C (zh) * 1994-05-18 2001-10-17 吸入治疗系统公司 干扰素干粉配方的方法及组合物
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
SE9700134D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9700136D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5612053A (en) * 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
EP0843565A4 (fr) * 1995-05-12 2002-10-16 Genentech Inc Administration d'un aerosol constitue de particules de grandes dimensions, contenant un produit a usage biologique
GB9606677D0 (en) * 1996-03-29 1996-06-05 Glaxo Wellcome Inc Process and device
US6503480B1 (en) 1997-05-23 2003-01-07 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US6254854B1 (en) 1996-05-24 2001-07-03 The Penn Research Foundation Porous particles for deep lung delivery
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
USRE37053E1 (en) 1996-05-24 2001-02-13 Massachusetts Institute Of Technology Particles incorporating surfactants for pulmonary drug delivery
US5976574A (en) * 1996-12-31 1999-11-02 Inhale Therapeutic Systems Processes for spray drying hydrophobic drugs in organic solvent suspensions
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20020017295A1 (en) * 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
EP1019020A1 (fr) † 1997-09-29 2000-07-19 Inhale Therapeutic Systems, Inc. Preparations bioactives stabilisees et leur procedes d'utilisation
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
JP2002509119A (ja) * 1998-01-13 2002-03-26 アストラゼネカ ユーケイ リミテッド ドーパミン（Ｄ２）レセプターアゴニスト活性を有する化合物およびβ２−アドレナリンレセプターアゴニスト活性を有する化合物（Ｂ）を含有する薬学的組成物
JP3828363B2 (ja) * 1998-04-20 2006-10-04 株式会社コスモ総合研究所 ポリエステル及びその製造法
US6451349B1 (en) 1998-08-19 2002-09-17 Quadrant Healthcare (Uk) Limited Spray-drying process for the preparation of microparticles
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US6858199B1 (en) * 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
CA2382821A1 (fr) * 1999-08-25 2001-03-01 Advanced Inhalation Research, Inc. Modulation de liberation a partir de formulations seches en poudre
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
HUP0300491A2 (en) 2000-02-28 2003-07-28 Vectura Ltd Improvements in or relating to the delivery of oral drugs
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
AU2001277230A1 (en) * 2000-08-01 2002-02-13 Inhale Therapeutic Systems, Inc. Apparatus and process to produce particles having a narrow size distribution andparticles made thereby
SE516555C2 (sv) * 2000-08-04 2002-01-29 Microdrug Ag Elektropulver
FI20002215A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
FI20002216A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
CA2433335C (fr) 2000-12-29 2010-04-20 Advanced Inhalation Research, Inc. Particules a liberation prolongee destinees a etre inhalees
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
US20030125236A1 (en) * 2000-12-29 2003-07-03 Advenced Inhalation Research, Inc. Particles for inhalation having rapid release properties
DE10128779A1 (de) † 2001-06-13 2003-01-02 Boehringer Ingelheim Pharma Verfahren zur Reinigung von Hartgelatinekapseln
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
WO2003020197A1 (fr) 2001-09-05 2003-03-13 Vectura Limited Perfectionnements dans ou ayant trait a l'administration orale de medicaments
DE60227691D1 (de) 2001-11-01 2008-08-28 Nektar Therapeutics Sprühtrocknungsverfahren
US7182961B2 (en) * 2001-11-20 2007-02-27 Advanced Inhalation Research, Inc. Particulate compositions for pulmonary delivery
WO2003043603A1 (fr) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Compositions particulaires destinees a augmenter la solubilite d'agents faiblement solubles
CA2468958C (fr) 2001-12-19 2012-07-03 Nektar Therapeutics Administration pulmonaire d'aminoglycosides
US20040014679A1 (en) * 2002-02-20 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co., Kg Inhalation powder containing the CGRP antagonist BIBN4096 and process for the preparation thereof
EP1490031A1 (fr) * 2002-03-07 2004-12-29 Vectura Limited Formulations a base de particules multiples a fusion rapide pour administration orale
US7582284B2 (en) * 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
EP1501479A1 (fr) * 2002-05-07 2005-02-02 Nektar Therapeutics Capsules pour inhalateurs a poudre seche et procedes de fabrication et d'utilisation correspondants
AU2003302329B2 (en) 2002-12-30 2010-01-07 Novartis Ag Prefilming atomizer
AU2004272077A1 (en) * 2003-09-10 2005-03-24 Map Pharmaceuticals, Inc. Aerosol formulations for delivery of dihydroergotamine to the systemic circulation via pulmonary inhalation
US20080213593A1 (en) * 2005-01-21 2008-09-04 President And Fellows Of Harvard College Systems And Methods For Forming Fluidic Droplets Encapsulated In Particles Such As Colloidal Particles
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
CA2677838C (fr) * 2007-02-11 2017-08-01 Map Pharmaceuticals, Inc. Procede d'administration therapeutique de dhe pour procurer un soulagement rapide de la migraine tout en minimisant le profil des effets secondaires
US20110171141A1 (en) * 2009-06-26 2011-07-14 Kellerman Donald J Administration of dihydroergotamine mesylate particles using a metered dose inhaler
CN102687071B (zh) 2009-12-09 2013-12-11 旭硝子株式会社 带反射层的euv光刻用衬底、euv光刻用反射型掩模坯料、euv光刻用反射型掩模、和该带反射层的衬底的制造方法
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
US9763965B2 (en) 2012-04-13 2017-09-19 Glaxosmithkline Intellectual Property Development Limited Aggregate particles
US20140275517A1 (en) * 2013-03-15 2014-09-18 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1569611A (en) * 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
GB1520248A (en) * 1975-07-24 1978-08-02 Fisons Ltd Sodium cromoglycate containing medicament
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
IE45260B1 (en) * 1976-01-23 1982-07-28 Fisons Ltd Pelletised or granular medicament formulation
GB1549229A (en) * 1976-09-23 1979-08-01 Fisons Ltd High density sodium cromoglycate

Also Published As

Publication number Publication date
NO156394C (no) 1987-09-16
CH657273A5 (fr) 1986-08-29
IL66375A0 (en) 1982-11-30
AU540826B2 (en) 1984-12-06
DK159716B (da) 1990-11-26
PT75310A (en) 1982-08-01
DK325982A (da) 1983-01-25
MA19548A1 (fr) 1983-04-01
SG68487G (en) 1988-02-19
PT75310B (en) 1985-11-29
EP0072046A1 (fr) 1983-02-16
AU8635582A (en) 1983-02-10
EP0072046B1 (fr) 1986-01-15
GR76229B (fr) 1984-08-04
KR840000226A (ko) 1984-02-18
FR2510405A1 (fr) 1983-02-04
JPS5859914A (ja) 1983-04-09
NZ201341A (en) 1985-05-31
FI822548A0 (fi) 1982-07-20
NO156394B (no) 1987-06-09
CA1187415A (fr) 1985-05-21
FI822548L (fi) 1983-01-25
KR890002908B1 (ko) 1989-08-11
IE821770L (en) 1983-01-24
IE53640B1 (en) 1989-01-04
BE893912A (fr) 1983-01-24
HU196904B (en) 1989-02-28
HK10088A (en) 1988-02-12
PH22759A (en) 1988-12-12
DE3268533D1 (en) 1986-02-27
ZA825222B (en) 1983-05-25
MY8700857A (en) 1987-12-31
NO822556L (no) 1983-01-25
US4590206A (en) 1986-05-20
LU84291A1 (fr) 1983-02-07
JPH0468285B2 (fr) 1992-11-02
DK159716C (da) 1991-04-29

Similar Documents

Publication Publication Date Title
FR2510405B1 (fr) Composition pharmaceutique a inhaler
DK304582A (da) Dosisinhalator
IL58209A0 (en) Medicament inhaler
GB8326878D0 (en) Administering medicaments to patients
GB8602264D0 (en) Administering medicaments to patients
AR229476A1 (es) Vendaje para administrar un medicamento
PH23643A (en) Nasal pharmaceutical composition
IT1214683B (it) Composizioni farmaceutiche nasali
BE894376A (fr) Preparation pharmaceutique
BE833394A (fr) Composition pharmaceutique destinee a faciliter l'accouchement
FR2532848B1 (fr) Composition pharmaceutique contenant un derive polyprenylique
IT1221041B (it) Composizione farmaceutica a cessione prolungata e procedimento per prepararla
DE3279806D1 (de) Corpuscules containing medicaments
IT1200099B (it) Composizioni farmaceutiche somministrabili per via nasale
CY1490A (en) Improvements in or relating to nasal pharmaceutical compositions
BE891013A (fr) Compositions pharmaceutique
FI830245A0 (fi) Foerbaettringar beroerande via naesan intagbara farmaceutiska kompositioner
BE890817A (fr) Medicaments pschycotropes
ATE9761T1 (de) Pharmazeutische zusammensetzung eines vincadimers.
FR2572652B1 (fr) Composition pharmaceutique a usage antiseptique
IT1174759B (it) Composizione farmaceutica contenente salbutamol b-stimolante
IT1141271B (it) Composizioni farmaceutiche ad attivita' antiulcera
RO78607A2 (fr) Composition medicamenteuse hipolipemianante-antiaterosclerotique
ES260154Y (es) Inhalador perfeccionado
DE3050005A1 (de) Breath actuated devices for administering powdered medicaments

Legal Events

Date Code Title Description
ST Notification of lapse