DE3268533D1 - Inhalation drugs, methods for their production and pharmaceutical formulations containing them - Google Patents

Inhalation drugs, methods for their production and pharmaceutical formulations containing them

Info

Publication number
DE3268533D1
DE3268533D1 DE8282200841T DE3268533T DE3268533D1 DE 3268533 D1 DE3268533 D1 DE 3268533D1 DE 8282200841 T DE8282200841 T DE 8282200841T DE 3268533 T DE3268533 T DE 3268533T DE 3268533 D1 DE3268533 D1 DE 3268533D1
Authority
DE
Germany
Prior art keywords
production
methods
pharmaceutical formulations
formulations containing
inhalation drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282200841T
Other languages
English (en)
Inventor
Raymond Brian Forrester
Terence David Boardman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10523464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3268533(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fisons Ltd filed Critical Fisons Ltd
Application granted granted Critical
Publication of DE3268533D1 publication Critical patent/DE3268533D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
DE8282200841T 1981-07-24 1982-07-06 Inhalation drugs, methods for their production and pharmaceutical formulations containing them Expired DE3268533D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8122846 1981-07-24

Publications (1)

Publication Number Publication Date
DE3268533D1 true DE3268533D1 (en) 1986-02-27

Family

ID=10523464

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282200841T Expired DE3268533D1 (en) 1981-07-24 1982-07-06 Inhalation drugs, methods for their production and pharmaceutical formulations containing them

Country Status (26)

Country Link
US (1) US4590206A (de)
EP (1) EP0072046B1 (de)
JP (1) JPS5859914A (de)
KR (1) KR890002908B1 (de)
AU (1) AU540826B2 (de)
BE (1) BE893912A (de)
CA (1) CA1187415A (de)
CH (1) CH657273A5 (de)
DE (1) DE3268533D1 (de)
DK (1) DK159716C (de)
FI (1) FI822548L (de)
FR (1) FR2510405B1 (de)
GR (1) GR76229B (de)
HK (1) HK10088A (de)
HU (1) HU196904B (de)
IE (1) IE53640B1 (de)
IL (1) IL66375A0 (de)
LU (1) LU84291A1 (de)
MA (1) MA19548A1 (de)
MY (1) MY8700857A (de)
NO (1) NO156394C (de)
NZ (1) NZ201341A (de)
PH (1) PH22759A (de)
PT (1) PT75310B (de)
SG (1) SG68487G (de)
ZA (1) ZA825222B (de)

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US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
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US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
ES2218543T3 (es) 1994-03-07 2004-11-16 Nektar Therapeutics Procedimiento y preparacion para la administracion de insulina por via pulmonar.
ATE299892T1 (de) * 1994-05-18 2005-08-15 Nektar Therapeutics Methoden und zusammensetzungen für die trockenpuderarznei aus interferonen
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9700134D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700136D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
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USRE37053E1 (en) 1996-05-24 2001-02-13 Massachusetts Institute Of Technology Particles incorporating surfactants for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US6254854B1 (en) 1996-05-24 2001-07-03 The Penn Research Foundation Porous particles for deep lung delivery
US6503480B1 (en) 1997-05-23 2003-01-07 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
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US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
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US20020017295A1 (en) * 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
ATE248583T1 (de) * 1997-09-29 2003-09-15 Nektar Therapeutics In dosierinhalatoren verwendbare, stabilisierte zubereitungen
EP1075278A1 (de) * 1998-01-13 2001-02-14 AstraZeneca UK Limited Pharmazeutische zusammenstellungen die eine verbindung mit dopamin d2rezeptor agonistaktivität und eine verbindung (b) mit beta2-adrenergischer aktivität enthalten
JP3828363B2 (ja) * 1998-04-20 2006-10-04 株式会社コスモ総合研究所 ポリエステル及びその製造法
US6451349B1 (en) 1998-08-19 2002-09-17 Quadrant Healthcare (Uk) Limited Spray-drying process for the preparation of microparticles
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US6858199B1 (en) * 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
EP1210067A2 (de) * 1999-08-25 2002-06-05 Advanced Inhalation Research, Inc. Modulation der freigabe aus trockenpulverformulierungen
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
ES2305057T3 (es) 2000-02-28 2008-11-01 Pharmakodex Limited Dispositivo para la administracion de farmacos orales.
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
ES2525087T5 (es) 2000-05-10 2018-06-28 Novartis Ag Polvos basados en fosfolípidos para administración de fármacos
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
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FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
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DE10128779A1 (de) † 2001-06-13 2003-01-02 Boehringer Ingelheim Pharma Verfahren zur Reinigung von Hartgelatinekapseln
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US20030129250A1 (en) * 2001-11-20 2003-07-10 Advanced Inhalation Research Inc. Particulate compositions for improving solubility of poorly soluble agents
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Family Cites Families (6)

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GB1569611A (en) * 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
GB1520248A (en) * 1975-07-24 1978-08-02 Fisons Ltd Sodium cromoglycate containing medicament
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Also Published As

Publication number Publication date
LU84291A1 (fr) 1983-02-07
KR890002908B1 (ko) 1989-08-11
NZ201341A (en) 1985-05-31
FR2510405B1 (fr) 1985-07-26
JPH0468285B2 (de) 1992-11-02
FI822548L (fi) 1983-01-25
CH657273A5 (fr) 1986-08-29
PT75310A (en) 1982-08-01
ZA825222B (en) 1983-05-25
BE893912A (fr) 1983-01-24
JPS5859914A (ja) 1983-04-09
IL66375A0 (en) 1982-11-30
FR2510405A1 (fr) 1983-02-04
GR76229B (de) 1984-08-04
IE53640B1 (en) 1989-01-04
HU196904B (en) 1989-02-28
AU540826B2 (en) 1984-12-06
SG68487G (en) 1988-02-19
NO822556L (no) 1983-01-25
MA19548A1 (fr) 1983-04-01
PH22759A (en) 1988-12-12
IE821770L (en) 1983-01-24
NO156394B (no) 1987-06-09
CA1187415A (en) 1985-05-21
EP0072046A1 (de) 1983-02-16
FI822548A0 (fi) 1982-07-20
DK159716C (da) 1991-04-29
MY8700857A (en) 1987-12-31
AU8635582A (en) 1983-02-10
KR840000226A (ko) 1984-02-18
DK159716B (da) 1990-11-26
PT75310B (en) 1985-11-29
US4590206A (en) 1986-05-20
HK10088A (en) 1988-02-12
DK325982A (da) 1983-01-25
EP0072046B1 (de) 1986-01-15
NO156394C (no) 1987-09-16

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation