LU82185A1 - Nouveaux derives hydroxyles de la pyrimidine, leur preparation et leur utilisation therapeutique - Google Patents

Nouveaux derives hydroxyles de la pyrimidine, leur preparation et leur utilisation therapeutique Download PDF

Info

Publication number
LU82185A1
LU82185A1 LU82185A LU82185A LU82185A1 LU 82185 A1 LU82185 A1 LU 82185A1 LU 82185 A LU82185 A LU 82185A LU 82185 A LU82185 A LU 82185A LU 82185 A1 LU82185 A1 LU 82185A1
Authority
LU
Luxembourg
Prior art keywords
preparation
pyrimidine
therapeutic use
pyrimidine derivatives
hydroxylated
Prior art date
Application number
LU82185A
Other languages
English (en)
French (fr)
Inventor
A Esanu
Original Assignee
Soc D Etudes Prod Chimique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26270867&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU82185(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Soc D Etudes Prod Chimique filed Critical Soc D Etudes Prod Chimique
Publication of LU82185A1 publication Critical patent/LU82185A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU82185A 1979-03-10 1980-02-20 Nouveaux derives hydroxyles de la pyrimidine, leur preparation et leur utilisation therapeutique LU82185A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB7908494 1979-03-10
GB7908494 1979-03-10
GB7914987 1979-04-30
GB7914987 1979-04-30

Publications (1)

Publication Number Publication Date
LU82185A1 true LU82185A1 (fr) 1980-06-06

Family

ID=26270867

Family Applications (1)

Application Number Title Priority Date Filing Date
LU82185A LU82185A1 (fr) 1979-03-10 1980-02-20 Nouveaux derives hydroxyles de la pyrimidine, leur preparation et leur utilisation therapeutique

Country Status (24)

Country Link
JP (1) JPS55122768A (ko)
AR (1) AR222691A1 (ko)
AU (1) AU533547B2 (ko)
BE (1) BE881752A (ko)
CA (1) CA1132561A (ko)
CH (1) CH644368A5 (ko)
DE (3) DE3009071C2 (ko)
EG (1) EG14282A (ko)
FI (1) FI66357C (ko)
FR (2) FR2451370A1 (ko)
GB (1) GB2045756B (ko)
HK (1) HK55383A (ko)
IE (1) IE49547B1 (ko)
IN (1) IN153791B (ko)
LU (1) LU82185A1 (ko)
MX (1) MX6218E (ko)
MY (1) MY8400200A (ko)
NL (1) NL184833C (ko)
NO (1) NO154054C (ko)
NZ (1) NZ192927A (ko)
OA (1) OA06484A (ko)
PT (1) PT70882A (ko)
SE (1) SE435180B (ko)
SG (1) SG22683G (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE894517A (fr) * 1981-10-16 1983-01-17 Sod Conseils Rech Applic Nouveau derive de l'isopropylamino pyrimidine, sa preparation et composition therapeutiques a base de ses composes
US4673677A (en) * 1983-10-03 1987-06-16 Pfizer Inc. Method for treatment of gastrointestinal disorders
US4554276A (en) * 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
US4711888A (en) 1985-07-24 1987-12-08 Pfizer Inc. Hydroxy and alkoxy pyrimidines
WO1989000423A1 (en) * 1987-07-09 1989-01-26 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
US4910204A (en) * 1988-06-28 1990-03-20 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
US4940712A (en) * 1989-05-26 1990-07-10 Pfizer Inc. Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors
US5270319A (en) * 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
US5220025A (en) * 1992-02-24 1993-06-15 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5196431A (en) * 1992-02-24 1993-03-23 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US9133212B1 (en) * 2005-06-15 2015-09-15 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB741667A (en) * 1952-12-05 1955-12-07 Ici Ltd New pyrimidine derivatives
GB756189A (en) * 1954-02-01 1956-08-29 Ici Ltd New pyrimidine derivatives
ZA711152B (en) * 1970-03-02 1971-11-24 Ici Ltd Manufacture of pyrimidines
GB1525995A (en) * 1976-02-18 1978-09-27 Soc D Etudes Prod Chimique Aminopyrimidine salt

Also Published As

Publication number Publication date
GB2045756B (en) 1983-01-26
NO154054C (no) 1986-07-09
AU533547B2 (en) 1983-12-01
NO800664L (no) 1980-09-11
CA1132561A (en) 1982-09-28
FI66357B (fi) 1984-06-29
FR2451191A1 (fr) 1980-10-10
FI66357C (fi) 1984-10-10
DE3050999C2 (de) 1986-08-14
DE3016752A1 (de) 1980-12-04
FI800566A (fi) 1980-09-11
EG14282A (en) 1983-09-30
DE3016752C2 (ko) 1987-06-25
NL184833C (nl) 1989-11-16
SG22683G (en) 1983-12-16
GB2045756A (en) 1980-11-05
OA06484A (fr) 1981-07-31
FR2451370A1 (fr) 1980-10-10
SE435180B (sv) 1984-09-10
NO154054B (no) 1986-04-01
AU5624880A (en) 1980-09-18
NZ192927A (en) 1981-07-13
DE3009071A1 (de) 1980-09-11
IN153791B (ko) 1984-08-18
SE8001812L (sv) 1980-09-11
IE49547B1 (en) 1985-10-30
NL184833B (nl) 1989-06-16
MX6218E (es) 1984-12-21
AR222691A1 (es) 1981-06-15
HK55383A (en) 1983-11-25
IE800477L (en) 1980-09-10
DE3050999A1 (ko) 1985-08-14
JPS6126996B2 (ko) 1986-06-23
DE3009071C2 (de) 1985-11-14
PT70882A (en) 1980-03-01
MY8400200A (en) 1984-12-31
FR2451191B1 (ko) 1983-04-29
JPS55122768A (en) 1980-09-20
CH644368A5 (en) 1984-07-31
NL184468B (nl) 1989-03-01
NL8001289A (nl) 1980-09-12
BE881752A (fr) 1980-05-30
FR2451370B1 (ko) 1983-05-13

Similar Documents

Publication Publication Date Title
CA2150162C (fr) Nouveau n-pyridyl carboxamides et derives, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
LU82185A1 (fr) Nouveaux derives hydroxyles de la pyrimidine, leur preparation et leur utilisation therapeutique
FR2555049A1 (fr) Medicaments a base de carboxymethoxy-7 furo-(3,4-c)-pyridine
FR2553409A1 (fr) Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
FR2501506A1 (fr) Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine
EP0906912B1 (fr) Nouveaux composés de l'indanol, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP0114770A2 (fr) Composés à noyau hétérocyclique diazoté, leur procédé de préparation et les médicaments, actifs sur le système nerveux central, qui en contiennent
FR2483929A1 (fr) Nouvelles adenosines n6-substituees utiles comme medicaments antihypertenseurs, compositions therapeutiques et formes pharmaceutiques les contenant, et leur procede de preparation
LU82332A1 (fr) Preparation des derives hydroxyles de l'isopropylamino-pyrimidine
EP0088023A2 (fr) Pyrido(3',4':4,5) furo(3,2-g) coumarines ou pyrido(3,4-h) psoralènes,obtention, applications en cosmétologie et à titre de médicaments, et compositions cosmétiques et pharmaceutiques les contenant
CH645103A5 (fr) Derives halogenes de l'isopropylamino pyrimidine, leur preparation et composition therapeutique les contenant.
FR2608157A1 (fr) Nouveaux derives de l'azaspirodecane, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant et intermediaires
FR2624861A1 (fr) Carbamates tricycliques, leur procede de preparation et leur application en therapeutique
EP0003920B1 (fr) Thiéno (3,2-c) et thiéno (2,3-c)pyridines, leur procédé de préparation et leur application en thérapeutique
EP0061406B1 (fr) Dérivés d'acide benzamido-alkyl-hydroxamique, procédé de préparation et composition thérapeutique
FR2520618A1 (fr) Application therapeutique de certains derives de la (trimethoxy-3,4,5) cinnamoyl-1 piperazine et de leurs sels d'acide
EP0256909A1 (fr) Acide N,N-bis-(4-fluorophényl) carbamoylacétohydroxamique et composition pharmaceutique le contenant
EP0347305B1 (fr) [(Aryl-4-pipérazinyl-1)-2 éthoxy]-3 p-cymène, les dérivés ortho, méta, para monosubstitués ou disubstitués sur le noyau phényle dudit produit, le procédé de préparation desdits dérivés, et les médicaments contenant lesdits composés comme principe actif
CA2346506C (fr) Derives d'aryl-{4-fluoro-4-[(2-pyridin-2-yl-ethylamino)-methyl]-piperidin-1-yl}-methanone comme agonistes du recepteur 5-ht1
FR2606015A1 (fr) Derives du benzhydrylthiomethane, leurs procedes de preparation et leurs applications en therapeutique
FR2518537A1 (fr) Nouveaux derives de l'acide phenylacetique, leur preparation et compositions les contenant
EP0135406A1 (fr) Pyrrolidinones actives sur le système nerveux central, leur procédé de préparation, les médicaments en contenant
FR2723372A1 (fr) Nouveaux derives de streptogramine, leur preparation et les compositions pharmaceutiques qui les contiennent
WO2002092598A1 (fr) DERIVES DE DIHYDROIMIDAZO [5,1-A]-β-CARBOLINE, LEUR PROCEDE DE PREPARATION ET LEUR APPLICATION A TITRE DE MEDICAMENT
EP0022737B1 (fr) Imines dérivées de l'amino-5 benzodioxole-1,3 utiles comme médicaments et leur préparation