LT5215B - Matricines metalproteinazes inhibuojanti kompozicija neoplazinėms ligoms gydyti - Google Patents

Matricines metalproteinazes inhibuojanti kompozicija neoplazinėms ligoms gydyti Download PDF

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Publication number
LT5215B
LT5215B LT2004074A LT2004074A LT5215B LT 5215 B LT5215 B LT 5215B LT 2004074 A LT2004074 A LT 2004074A LT 2004074 A LT2004074 A LT 2004074A LT 5215 B LT5215 B LT 5215B
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LT
Lithuania
Prior art keywords
composition
matrix metalloproteinases
matrix
diseases
ascorbic acid
Prior art date
Application number
LT2004074A
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English (en)
Lithuanian (lt)
Other versions
LT2004074A (en
Inventor
Matthias Rath
Shrirang Netke
Vadim Ivanov
Waheed Roomi
Aleksandra Niedzwiecki
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Matthias Rath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matthias Rath filed Critical Matthias Rath
Publication of LT2004074A publication Critical patent/LT2004074A/xx
Publication of LT5215B publication Critical patent/LT5215B/lt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
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    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00Antineoplastic agents
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    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
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    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
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  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
LT2004074A 2002-01-08 2004-08-05 Matricines metalproteinazes inhibuojanti kompozicija neoplazinėms ligoms gydyti LT5215B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/041,427 US6939860B2 (en) 2002-01-08 2002-01-08 Composition and method for treatment of neoplastic diseases associated with elevated matrix metalloproteinase activities using catechin compounds

Publications (2)

Publication Number Publication Date
LT2004074A LT2004074A (en) 2004-12-27
LT5215B true LT5215B (lt) 2005-05-25

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LT2004074A LT5215B (lt) 2002-01-08 2004-08-05 Matricines metalproteinazes inhibuojanti kompozicija neoplazinėms ligoms gydyti

Country Status (29)

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US (3) US6939860B2 (xx)
EP (1) EP1463498B1 (xx)
JP (1) JP4144800B2 (xx)
KR (1) KR20050005408A (xx)
CN (1) CN1612731A (xx)
AT (1) ATE439833T1 (xx)
AU (2) AU2002244690A1 (xx)
BR (1) BR0208052A (xx)
CA (1) CA2469162A1 (xx)
CZ (1) CZ2004853A3 (xx)
DE (1) DE60233433D1 (xx)
EE (1) EE200400031A (xx)
ES (1) ES2332126T3 (xx)
HR (1) HRP20040705A2 (xx)
HU (1) HUP0402421A3 (xx)
IL (1) IL162384A0 (xx)
LT (1) LT5215B (xx)
LV (1) LV13249B (xx)
MX (1) MXPA04006627A (xx)
NO (1) NO20033949L (xx)
NZ (1) NZ533353A (xx)
PL (1) PL371205A1 (xx)
RU (1) RU2284185C2 (xx)
SI (1) SI21871A (xx)
SK (1) SK2772004A3 (xx)
TR (1) TR200401669T1 (xx)
UA (1) UA78979C2 (xx)
WO (1) WO2003057211A1 (xx)
ZA (1) ZA200404915B (xx)

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WO2006053184A2 (en) * 2004-11-10 2006-05-18 The Trustees Of Columbia University In The City Of New York Methods for treating or preventing a vascular disease
ES2246737B1 (es) * 2005-06-09 2006-12-01 Jose Juan Rodriguez Jerez "composicion farmaceutica que comprende lisina y usos correspondientes".
JP5101521B2 (ja) * 2005-12-29 2012-12-19 三井農林株式会社 メチシリン耐性黄色ブドウ球菌をオキサシリンに対し感作する組成物および方法
US20070265211A1 (en) * 2006-05-12 2007-11-15 Matthias Rath Novel composition and method effective in inhibiting the atherogenic process
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ES2534245T3 (es) 2008-11-04 2015-04-20 Vymedic, Llc Formulaciones de suplemento antiviral
WO2011046199A1 (ja) * 2009-10-16 2011-04-21 株式会社カネカ 還元型補酵素q10の製造方法、安定化方法及びそれを含有する組成物
EP2648721B1 (de) 2011-01-31 2018-09-19 LUCOLAS-M.D. Ltd. Kombinationen von aromatase inhibitoren und antioxidanzien
KR101829330B1 (ko) 2011-04-13 2018-02-20 (주)아모레퍼시픽 염증성 피부 노화 억제 물질 스크리닝 방법
CN102526170B (zh) * 2011-12-31 2015-04-29 许学志 抗结核杆菌的儿茶提取物组合物、其制备方法及含有它们的药物制剂和应用
BE1023772B9 (fr) * 2013-05-17 2017-08-02 Valore Composition a base d'un complexe de (+)-catechine et d'acide amine pour le traitement et la prevention du cancer
CN104096058A (zh) * 2014-07-02 2014-10-15 胥玲 一种治疗扩张型心肌病的中药药丸
BE1022579A9 (fr) * 2014-11-10 2016-10-06 Valore Composition antimétastatique comprenant au moins un composé de type flavanol
WO2024003061A1 (en) * 2022-06-30 2024-01-04 Lo.Li. Pharma S.R.L. Composition for the treatment of the human papillomavirus infection (hpv)

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JP4629978B2 (ja) * 2002-02-25 2011-02-09 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド サイトカイン媒介疾患の治療に有用な1,4−二置換ベンゾ縮合シクロアルキル尿素化合物

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LT2004074A (en) 2004-12-27
NZ533353A (en) 2007-04-27
KR20050005408A (ko) 2005-01-13
AU2008203157A1 (en) 2008-08-07
SI21871A (sl) 2006-04-30
EP1463498A1 (en) 2004-10-06
JP4144800B2 (ja) 2008-09-03
US20050032715A1 (en) 2005-02-10
BR0208052A (pt) 2005-01-04
SK2772004A3 (en) 2004-12-01
HRP20040705A2 (en) 2004-10-31
JP2005513166A (ja) 2005-05-12
US20050281794A1 (en) 2005-12-22
LV13249B (en) 2005-07-20
RU2004124047A (ru) 2005-04-20
NO20033949L (no) 2003-11-04
IL162384A0 (en) 2005-11-20
EE200400031A (et) 2004-04-15
CN1612731A (zh) 2005-05-04
ES2332126T3 (es) 2010-01-27
HUP0402421A2 (hu) 2005-07-28
RU2284185C2 (ru) 2006-09-27
ZA200404915B (en) 2006-07-26
WO2003057211A1 (en) 2003-07-17
DE60233433D1 (de) 2009-10-01
CZ2004853A3 (cs) 2004-12-15
HUP0402421A3 (en) 2008-02-28
NO20033949D0 (no) 2003-09-05
MXPA04006627A (es) 2004-11-10
TR200401669T1 (tr) 2007-01-22
CA2469162A1 (en) 2003-07-17
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US20030130201A1 (en) 2003-07-10
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