LT5064B - Avies pararaupų viruso kamienai, skirti panaudoti prieš organų fibrozę - Google Patents

Avies pararaupų viruso kamienai, skirti panaudoti prieš organų fibrozę Download PDF

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Publication number
LT5064B
LT5064B LT2003008A LT2003008A LT5064B LT 5064 B LT5064 B LT 5064B LT 2003008 A LT2003008 A LT 2003008A LT 2003008 A LT2003008 A LT 2003008A LT 5064 B LT5064 B LT 5064B
Authority
LT
Lithuania
Prior art keywords
fibrosis
preventive
manufacture
curative effect
human
Prior art date
Application number
LT2003008A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT2003008A (en
Inventor
Claudia Hirth-Dietrich
Tobias Schlapp
Angela Siegling
Andreas Knorr
Olaf Weber
Gudrun Theiss
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10122233A external-priority patent/DE10122233A1/de
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of LT2003008A publication Critical patent/LT2003008A/xx
Publication of LT5064B publication Critical patent/LT5064B/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24211—Parapoxvirus, e.g. Orf virus
    • C12N2710/24232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
LT2003008A 2000-07-11 2003-02-03 Avies pararaupų viruso kamienai, skirti panaudoti prieš organų fibrozę LT5064B (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10033581 2000-07-11
DE10122233A DE10122233A1 (de) 2000-07-11 2001-05-08 Verwendung von Stämmen des Parapoxvirus ovis gegen Organfibrosen

Publications (2)

Publication Number Publication Date
LT2003008A LT2003008A (en) 2003-07-25
LT5064B true LT5064B (lt) 2003-11-25

Family

ID=26006334

Family Applications (1)

Application Number Title Priority Date Filing Date
LT2003008A LT5064B (lt) 2000-07-11 2003-02-03 Avies pararaupų viruso kamienai, skirti panaudoti prieš organų fibrozę

Country Status (30)

Country Link
US (1) US6632647B2 (sv)
EP (1) EP1303302B1 (sv)
JP (1) JP5106736B2 (sv)
CN (1) CN1452496B (sv)
AR (1) AR028800A1 (sv)
AU (2) AU8582701A (sv)
BG (1) BG107447A (sv)
CA (1) CA2415399C (sv)
CZ (1) CZ200372A3 (sv)
DK (1) DK200300014A (sv)
EE (1) EE200300019A (sv)
FI (1) FI20030038A (sv)
GB (1) GB2383752B (sv)
HK (1) HK1054330B (sv)
HR (1) HRP20030097A2 (sv)
HU (1) HU227668B1 (sv)
IL (1) IL153826A0 (sv)
LT (1) LT5064B (sv)
LU (1) LU90996B1 (sv)
LV (1) LV12991B (sv)
MA (1) MA25765A1 (sv)
MX (1) MXPA03000278A (sv)
NO (1) NO20030081L (sv)
NZ (1) NZ523535A (sv)
PL (1) PL360839A1 (sv)
RU (1) RU2003104522A (sv)
SE (1) SE0300033L (sv)
SI (1) SI21171A (sv)
SK (1) SK382003A3 (sv)
WO (1) WO2002004019A2 (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19922407A1 (de) * 1999-05-14 2000-11-16 Bayer Ag Organ-, gewebs- und zellspezifisches Immuntherapeutikum für chronische virale Infektionen, sowie entzündliche, degenerative und proliferative Erkrankungen insbesondere der Leber sowie Krebs auf der Basis von rekombinantem Parapoxvirus
US6752995B2 (en) 2002-04-15 2004-06-22 Board Of Regents, The University Of Texas System Nucleic acid and polypeptide sequences useful as adjuvants
EP1499355A4 (en) 2001-12-07 2005-10-05 Bayer Pharmaceuticals Corp USE OF PARAPOX B2L PROTEIN FOR THE TREATMENT OF CANCER AND THE MODIFICATION OF IMMUNE RESPONSES
EP1574211A1 (en) 2004-03-09 2005-09-14 Inserm Use of antagonists of the CB1 receptor for the manufacture of a composition useful for the treatment of hepatic diseases
WO2012045473A1 (en) * 2010-10-07 2012-04-12 Technische Universität München Viruses for the treatment of fibrosis
CA3018307A1 (en) * 2016-02-16 2017-08-24 Osaka University Pharmaceutical composition for use in treating fibrosis
TW201919675A (zh) * 2017-09-07 2019-06-01 德商艾庫瑞斯公司 使用羊副痘疹病毒(Parapoxvirus ovis；PPVO)及至少一種額外抗病毒藥之經B型肝炎病毒(HBV)感染之個體之組合療法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3504940A1 (de) 1984-02-17 1985-10-31 Mayr, Anton, Prof. Dr.med.vet. Dr.h.c.mult., 8000 München Multipotente paramunitaetsmediatoren, verfahren zu ihrer herstellung und diese mediatoren enthaltende arzneimittel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714665A1 (de) * 1977-04-01 1978-10-05 Mayr Anton Praeparat zur behandlung von herpes zoster und anderen herpes-infektionen, sowie verfahren zu seiner herstellung
US4360510A (en) * 1979-11-30 1982-11-23 Proctor Julian W Method for screening anti-tumor agents of the reticulo-endothelial stimulant class
US4663306A (en) * 1983-09-23 1987-05-05 Ribi Immunochem Research, Inc. Pyridine-soluble extract-refined detoxified endotoxin composition and use
DE3816139A1 (de) * 1987-10-17 1989-04-27 Bayer Ag Verfahren zur herstellung von paramunitaetsinducern
DE4405841C1 (de) 1994-02-23 1995-01-05 Mayr Anton Prof Dr Med Vet Dr Multipotente Paramunitätsinducer auf der Basis von Kombinationen von Pockenviruskomponenten, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO1997038724A1 (de) * 1996-04-15 1997-10-23 Anton Mayr Neue indikationen für die verwendung von multipotenten paramunitätsinducern aus attenuierten, nicht-immunogenen pockenviren oder parapockenviren als arzneimittel
DE19922407A1 (de) * 1999-05-14 2000-11-16 Bayer Ag Organ-, gewebs- und zellspezifisches Immuntherapeutikum für chronische virale Infektionen, sowie entzündliche, degenerative und proliferative Erkrankungen insbesondere der Leber sowie Krebs auf der Basis von rekombinantem Parapoxvirus
IL139593A (en) * 2000-11-09 2010-12-30 Biogem Optical Ltd Method for the detection of viable microorganisms

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3504940A1 (de) 1984-02-17 1985-10-31 Mayr, Anton, Prof. Dr.med.vet. Dr.h.c.mult., 8000 München Multipotente paramunitaetsmediatoren, verfahren zu ihrer herstellung und diese mediatoren enthaltende arzneimittel

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BHUNCHET E, WAKE K.: "Role of mesenchymal cell populations in porcine serum-induced rat liver fibrosis", HEPATOLOGY, 1992, pages 1452 - 1473
JOHNSON, S. J., HINES, J. E., BURT, A. D.: "Phenotypic modulation of perisinusoidal cells following acute liver injury: a quantitative analysis", INT. J. EXP. PATH., 1992, pages 765 - 772
MCLEAN EK, MCLEAN AE, SUTTON PM.: "Instant cirrhosis. An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobarbitone", BR J EXP PATHOL., 1969, pages 502 - 506

Also Published As

Publication number Publication date
IL153826A0 (en) 2003-07-31
JP5106736B2 (ja) 2012-12-26
HK1054330A1 (en) 2003-11-28
NO20030081D0 (no) 2003-01-08
GB2383752A (en) 2003-07-09
WO2002004019A3 (de) 2002-08-01
HK1054330B (zh) 2005-07-15
AU2001285827B2 (en) 2006-11-30
SI21171A (sl) 2003-10-31
LV12991B (en) 2003-08-20
MA25765A1 (fr) 2003-04-01
US20020076418A1 (en) 2002-06-20
HRP20030097A2 (en) 2005-02-28
AU8582701A (en) 2002-01-21
JP2004502741A (ja) 2004-01-29
CA2415399C (en) 2011-11-08
AR028800A1 (es) 2003-05-21
HUP0303830A3 (en) 2004-10-28
BG107447A (bg) 2003-09-30
EE200300019A (et) 2004-10-15
CN1452496A (zh) 2003-10-29
GB0302629D0 (en) 2003-03-12
SE0300033D0 (sv) 2003-01-10
LU90996B1 (en) 2003-01-08
CA2415399A1 (en) 2003-01-08
WO2002004019A2 (de) 2002-01-17
HUP0303830A2 (hu) 2004-04-28
HU227668B1 (en) 2011-11-28
MXPA03000278A (es) 2004-04-05
NZ523535A (en) 2004-12-24
CZ200372A3 (cs) 2003-05-14
US6632647B2 (en) 2003-10-14
EP1303302B1 (de) 2009-10-14
GB2383752B (en) 2004-11-24
LT2003008A (en) 2003-07-25
EP1303302A2 (de) 2003-04-23
NO20030081L (no) 2003-01-08
CN1452496B (zh) 2012-10-10
SE0300033L (sv) 2003-03-10
RU2003104522A (ru) 2004-06-27
FI20030038A (sv) 2003-03-10
DK200300014A (da) 2003-03-07
PL360839A1 (en) 2004-09-20
SK382003A3 (en) 2003-07-01

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Owner name: AICURIS GMBH & CO. KG, DE

Effective date: 20060824

MM9A Lapsed patents

Effective date: 20140711