LT4042B - A hypotensive composition and a process for the preraration thereof - Google Patents

A hypotensive composition and a process for the preraration thereof Download PDF

Info

Publication number
LT4042B
LT4042B LT95-084A LT95084A LT4042B LT 4042 B LT4042 B LT 4042B LT 95084 A LT95084 A LT 95084A LT 4042 B LT4042 B LT 4042B
Authority
LT
Lithuania
Prior art keywords
weight
nifedipine
solution
ethyl oleate
percent
Prior art date
Application number
LT95-084A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT95084A (en
Inventor
Margit Nagy
Csaba Farsang
Lidia Fedina
Katalin Szemeredi
Gabor Szenasi
Janos Egri
Antal Mosonyi
Borbala Barta
Gizella Toth
Ibolya Nyaradi
Frigyes Gorenyi
Zsuzsa Orr
Geza Floris
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of LT95084A publication Critical patent/LT95084A/xx
Publication of LT4042B publication Critical patent/LT4042B/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LT95-084A 1994-07-26 1995-07-20 A hypotensive composition and a process for the preraration thereof LT4042B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9402193A HU214582B (hu) 1994-07-26 1994-07-26 Porlasztható, vérnyomáscsökkentő hatású gyógyszerkészítmény és eljárás előállítására

Publications (2)

Publication Number Publication Date
LT95084A LT95084A (en) 1996-06-25
LT4042B true LT4042B (en) 1996-09-25

Family

ID=10985460

Family Applications (1)

Application Number Title Priority Date Filing Date
LT95-084A LT4042B (en) 1994-07-26 1995-07-20 A hypotensive composition and a process for the preraration thereof

Country Status (18)

Country Link
JP (1) JPH08169829A (lv)
AT (1) AT402690B (lv)
AU (1) AU699386B2 (lv)
BE (1) BE1011413A4 (lv)
CZ (1) CZ286399B6 (lv)
DE (1) DE19527140A1 (lv)
EE (1) EE9500029A (lv)
FR (1) FR2722988B1 (lv)
GB (1) GB2291593B (lv)
HR (1) HRP950374A2 (lv)
HU (1) HU214582B (lv)
IT (1) IT1277348B1 (lv)
LT (1) LT4042B (lv)
LV (1) LV11026B (lv)
PL (1) PL181069B1 (lv)
SK (1) SK280463B6 (lv)
UA (1) UA39880C2 (lv)
YU (1) YU50795A (lv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7632517B2 (en) 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
EP2042161A1 (en) * 1997-10-01 2009-04-01 Novadel Pharma Inc. Propellant-free spray composition comprising anti-emetic agent
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
EP1848270B1 (en) * 2005-02-17 2014-05-21 Abbott Laboratories Transmucosal administration of drug compositions for treating and preventing disorders in animals
DE102006027794A1 (de) * 2006-06-16 2007-12-20 Lts Lohmann Therapie-Systeme Ag Antihypertonie-Kombinationswafer
FR2906140B1 (fr) * 2006-09-22 2008-12-05 Philippe Perovitch Forme galenique pour l'administration par voie trans-muqueuse de principes actifs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307422A1 (de) 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen
EP0190292A1 (de) 1984-08-23 1986-08-13 Kuhlemann & Co Pharmazeutische zubereitung.
DE3544692A1 (de) 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1293929C (en) * 1986-03-10 1992-01-07 Kurt Burghart Pharmaceutical composition containing nifedipine
ES2042527T3 (es) * 1986-11-14 1993-12-16 Theratech Inc Un metodo para preparar una composicion farmaceutica aumentadora de la penetracion para la aplicacion topica.
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
JPS63170316A (ja) * 1986-12-30 1988-07-14 Fujimoto Seiyaku Kk ニフエジピン経皮吸収外用製剤
DE3714402A1 (de) * 1987-04-30 1988-11-10 Kali Chemie Pharma Gmbh Arzneimittelformulierung
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
AT391269B (de) * 1988-12-30 1990-09-10 Burghart Kurt Pharmazeutische zubereitung
US5298258A (en) * 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation
HU205249B (en) * 1990-11-09 1992-04-28 Egyt Gyogyszervegyeszeti Gyar Process for producing suspensive aerosole composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307422A1 (de) 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen
EP0190292A1 (de) 1984-08-23 1986-08-13 Kuhlemann & Co Pharmazeutische zubereitung.
DE3544692A1 (de) 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung

Also Published As

Publication number Publication date
PL309757A1 (en) 1996-02-05
AU699386B2 (en) 1998-12-03
ITMI951621A0 (it) 1995-07-26
DE19527140A1 (de) 1996-02-01
LV11026A (lv) 1996-02-20
FR2722988A1 (fr) 1996-02-02
UA39880C2 (uk) 2001-07-16
EE9500029A (et) 1996-02-15
IT1277348B1 (it) 1997-11-10
BE1011413A4 (fr) 1999-09-07
HUT75457A (en) 1997-05-28
GB2291593B (en) 1998-03-11
HRP950374A2 (en) 1997-10-31
YU50795A (sh) 1998-05-15
ATA121495A (de) 1996-12-15
CZ181195A3 (en) 1996-02-14
LT95084A (en) 1996-06-25
FR2722988B1 (fr) 1999-10-08
AT402690B (de) 1997-07-25
PL181069B1 (pl) 2001-05-31
SK280463B6 (sk) 2000-02-14
GB2291593A (en) 1996-01-31
JPH08169829A (ja) 1996-07-02
LV11026B (en) 1996-04-20
SK92295A3 (en) 1996-05-08
HU214582B (hu) 1998-04-28
GB9515205D0 (en) 1995-09-20
ITMI951621A1 (it) 1997-01-26
AU2326995A (en) 1996-02-08
HU9402193D0 (en) 1994-09-28
CZ286399B6 (en) 2000-04-12

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Effective date: 19990720