LT3714B - Inhibitors of cells proliferation, pharmaceutical composition and method for preparation of compounds - Google Patents

Inhibitors of cells proliferation, pharmaceutical composition and method for preparation of compounds Download PDF

Info

Publication number
LT3714B
LT3714B LTIP610A LTIP610A LT3714B LT 3714 B LT3714 B LT 3714B LT IP610 A LTIP610 A LT IP610A LT IP610 A LTIP610 A LT IP610A LT 3714 B LT3714 B LT 3714B
Authority
LT
Lithuania
Prior art keywords
compounds
formula
asp
group
pglu
Prior art date
Application number
LTIP610A
Other languages
English (en)
Lithuanian (lt)
Inventor
Ole Didrik Laerum
Original Assignee
Hafslund Nycomed Bioreg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hafslund Nycomed Bioreg filed Critical Hafslund Nycomed Bioreg
Publication of LTIP610A publication Critical patent/LTIP610A/xx
Publication of LT3714B publication Critical patent/LT3714B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4722—G-proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C07K7/067—Hemoregulatory peptides based on sequence Glp-Glu-Asp-Cys-Lys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTIP610A 1988-09-16 1993-06-03 Inhibitors of cells proliferation, pharmaceutical composition and method for preparation of compounds LT3714B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888821785A GB8821785D0 (en) 1988-09-16 1988-09-16 Peptide compounds

Publications (2)

Publication Number Publication Date
LTIP610A LTIP610A (en) 1994-12-27
LT3714B true LT3714B (en) 1996-02-26

Family

ID=10643722

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP610A LT3714B (en) 1988-09-16 1993-06-03 Inhibitors of cells proliferation, pharmaceutical composition and method for preparation of compounds

Country Status (22)

Country Link
US (1) US5484770A (de)
EP (2) EP0434718A1 (de)
JP (1) JPH04500666A (de)
KR (1) KR900701828A (de)
CN (1) CN1041159A (de)
AT (1) ATE110742T1 (de)
AU (1) AU641366B2 (de)
CA (1) CA1339947C (de)
DE (1) DE68917837T2 (de)
DK (1) DK39591A (de)
ES (1) ES2058479T3 (de)
GB (1) GB8821785D0 (de)
GE (1) GEP19971041B (de)
HU (2) HU208027B (de)
IE (1) IE64181B1 (de)
LT (1) LT3714B (de)
LV (1) LV10108B (de)
MY (1) MY104909A (de)
NZ (1) NZ230654A (de)
RU (1) RU2079509C1 (de)
WO (1) WO1990002753A1 (de)
ZA (1) ZA896980B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5620957A (en) * 1989-07-14 1997-04-15 Smithkline Beecham Corporation Hemoregulatory peptides
HU206372B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing new oligopeptides which selectively inhibit proliferation of haemopoietic cells and pharmaceutical compositions comprising same
HU206374B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing pentapeptide and its salts specifically inhibiting proliferation of epidermic cells, as well as pharmaceutical compositions comprising same as active ingredient
TW222280B (de) * 1991-11-26 1994-04-11 Smithkline Beecham Corp
IL104323A0 (en) * 1992-01-10 1993-05-13 Smithkline Beecham Corp Hemoregulatory peptides
GB9211674D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9211677D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9211668D0 (en) * 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GR1001502B (el) * 1992-11-26 1994-02-28 Smithkline Beecham Corp Αιμορυ?μιστικά πεπτίδια.
CN1034735C (zh) * 1993-01-02 1997-04-30 史密丝克莱恩比彻姆公司 血调节肽
US5521284A (en) * 1994-08-01 1996-05-28 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide amides and esters
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters
CN1403474A (zh) * 2001-09-05 2003-03-19 中国人民解放军军事医学科学院生物工程研究所 一种短肽及以其为活性成份的药物
RU2373220C2 (ru) 2002-07-23 2009-11-20 Сосьете Де Консей Де Решерш Э Д`Аппликасьон Сьентифик (С.К.Р.А.С.) Аналоги грелина

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112656A2 (de) 1982-11-26 1984-07-04 Nycomed As Peptidverbindungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO860752L (no) * 1985-06-26 1986-12-29 Bio Tech As Pentapeptider med cellevekstregulerende virkning og fremgangsmaate for fremstilling derav.
US4748154A (en) * 1985-12-24 1988-05-31 Takeda Chemical Industries, Ltd. Peptide derivatives, their production and use
GB8626539D0 (en) * 1986-11-06 1986-12-10 Nycomed As Peptide compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112656A2 (de) 1982-11-26 1984-07-04 Nycomed As Peptidverbindungen

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
E. SCHRODER, K. LUBKE: "The Peptides (Vol. 1)"
E. SCHRODER, K. LUBKE: "The Peptides (Vol. 2)"
ERIC ATHERTON, CHRISTOPHER J. LOGAN, ROBERT C: "Peptide synthesis. Part 2. Procedures for solid-phase synthesis using Nα-fluorenylmethoxycarbonylamino-acids on polyamide supports. Synthesis of substance P and of acyl carrier protein 65â€"74 decapeptide", J. CHEM. SOC., PERKIN TRANS. 1, 1981, pages 538 - 546, XP001070482, DOI: doi:10.1039/p19810000538
G. R. PETTIT: "Synthesic Peptides"
HEINRIKSON R. L., MEREDITH S. C.: "Amino acid analysis by reverse-phase high-performance liquid chromatography: precolumn derivatization with phenylisothiocyanate", ANAL BIOCHEM., 1984, pages 65 - 74, XP024827973, DOI: doi:10.1016/0003-2697(84)90307-5
HOUBEN-WEYL: "Methoden der organischen Chemie"
JAMES P. TAM, FOE S. TJOENG, R. B. MERRIFIELD: "Design and synthesis of multidetachable resin supports for solid-phase peptide synthesis", J. AM. CHEM. SOC., 1980, pages 6117 - 6127
JAMES P. TAM, R D. DIMARCHI, R. B. MERRIFIELD: "Photolabile multi-detachable p-alkoxybenzyl alcohol resin supports for peptide fragment or semi-synthesis", INT J PEPT PROTEIN RES, 1980, pages 412 - 425, XP055317669
MANFRED MUTTER, DIETER BELLOF: "A New Base-Labile Anchoring Group for Polymer-Supported Peptide Synthesis", HELVETICA CHIMICA ACTA, 1984, pages 2009 - 2016

Also Published As

Publication number Publication date
DE68917837T2 (de) 1994-12-22
DK39591D0 (da) 1991-03-06
AU641366B2 (en) 1993-09-23
US5484770A (en) 1996-01-16
MY104909A (en) 1994-06-30
WO1990002753A1 (en) 1990-03-22
ES2058479T3 (es) 1994-11-01
JPH04500666A (ja) 1992-02-06
DK39591A (da) 1991-03-06
EP0359338A1 (de) 1990-03-21
AU4218389A (en) 1990-04-02
RU2079509C1 (ru) 1997-05-20
NZ230654A (en) 1991-10-25
EP0434718A1 (de) 1991-07-03
IE64181B1 (en) 1995-07-12
HU895788D0 (en) 1991-08-28
CN1041159A (zh) 1990-04-11
GEP19971041B (en) 1997-11-26
IE892954L (en) 1990-03-16
ATE110742T1 (de) 1994-09-15
DE68917837D1 (de) 1994-10-06
GB8821785D0 (en) 1988-10-19
CA1339947C (en) 1998-07-07
LV10108B (en) 1994-10-20
LTIP610A (en) 1994-12-27
EP0359338B1 (de) 1994-08-31
HUT58765A (en) 1992-03-30
KR900701828A (ko) 1990-12-04
LV10108A (lv) 1994-05-10
ZA896980B (en) 1990-06-27
HU208027B (en) 1993-07-28

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Legal Events

Date Code Title Description
PC9A Transfer of patents

Free format text: NYCOMED IMAGING AS,NYCOVEIEN 1-2, N-0401 OSLO 4,NO,19961106

PD9A Change of patent owner

Free format text: HAFSLUND ASA,SLEMDALSVEIEN 37, N-0301 OSLO 3,NO,19961106,

MM9A Lapsed patents

Effective date: 19980603