LT3463B - Process for preparing pure isoflavone derivatives - Google Patents

Process for preparing pure isoflavone derivatives Download PDF

Info

Publication number
LT3463B
LT3463B LTIP779A LTIP779A LT3463B LT 3463 B LT3463 B LT 3463B LT IP779 A LTIP779 A LT IP779A LT IP779 A LTIP779 A LT IP779A LT 3463 B LT3463 B LT 3463B
Authority
LT
Lithuania
Prior art keywords
general formula
product
formula
vii
reaction mixture
Prior art date
Application number
LTIP779A
Other languages
English (en)
Lithuanian (lt)
Inventor
Tamas Kallay
Gyorgy Lanyi
Laszlo Ledniczky
Lajos Imrei
Gyorgy Hoffmann
Maria Sziladi
Eva Somfai
Tibor Montay
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of LTIP779A publication Critical patent/LTIP779A/xx
Publication of LT3463B publication Critical patent/LT3463B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Train Traffic Observation, Control, And Security (AREA)
LTIP779A 1990-04-06 1993-07-13 Process for preparing pure isoflavone derivatives LT3463B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/HU1990/000023 WO1991015483A1 (en) 1990-04-06 1990-04-06 An improved process for the preparation of substituted isoflavone derivatives

Publications (2)

Publication Number Publication Date
LTIP779A LTIP779A (en) 1995-01-31
LT3463B true LT3463B (en) 1995-10-25

Family

ID=10980899

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP779A LT3463B (en) 1990-04-06 1993-07-13 Process for preparing pure isoflavone derivatives

Country Status (15)

Country Link
US (1) US5247102A (ja)
EP (1) EP0478558B1 (ja)
JP (1) JPH089610B2 (ja)
KR (1) KR0149172B1 (ja)
AT (1) ATE101143T1 (ja)
AU (1) AU631860B2 (ja)
CA (1) CA2058619C (ja)
DE (1) DE69006502T2 (ja)
DK (1) DK0478558T3 (ja)
FI (1) FI915741A0 (ja)
HK (1) HK1003995A1 (ja)
LT (1) LT3463B (ja)
NO (1) NO300733B1 (ja)
RU (1) RU2036918C1 (ja)
WO (1) WO1991015483A1 (ja)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002603A (en) * 1989-12-04 1991-03-26 Board Of Trustees Operating Michigan State University Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi
US5204369A (en) * 1991-07-01 1993-04-20 The Endowment For Research In Human Biology Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse
FR2689127B1 (fr) * 1992-03-31 1994-05-06 Adir Cie Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant.
EP1477178A3 (en) * 1992-05-19 2005-02-16 KELLY, Graham Edmund Health supplements containing phyto-oestrogens, analogues or metabolites thereof
HUT68558A (en) * 1993-07-20 1995-06-28 Chinoin Gyogyszer Es Vegyeszet Method for preparing isoflavon derivatives
US5670632A (en) * 1996-01-18 1997-09-23 Acds Technologies, Ltd. Process for obtaining an isoflavone concentrate from a soybean extract
AUPO203996A0 (en) * 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
US6146668A (en) 1997-04-28 2000-11-14 Novogen, Inc. Preparation of isoflavones from legumes
US6255497B1 (en) 1997-04-29 2001-07-03 The Endowment For Research In Human Biology, Inc. Method for the inhibition of ALDH-I useful in the treatment of alcohol dependence or alcohol abuse
CA2287965C (en) * 1997-05-01 2009-10-20 Graham Edmund Kelly Treatment or prevention of menopausal symptoms and osteoporosis
AUPP112497A0 (en) * 1997-12-24 1998-01-22 Novogen Research Pty Ltd Compositions and method for protecting skin from UV induced immunosupression and skin damage
IT1298619B1 (it) * 1998-03-10 2000-01-12 Erregierre Spa Processo di preparazione dell'epriflavone
AUPP260798A0 (en) * 1998-03-26 1998-04-23 Novogen Research Pty Ltd Treatment of medical related conditions with isoflavone containing extracts of clover
US20090233999A1 (en) * 1999-09-06 2009-09-17 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ266199A0 (en) * 1999-09-06 1999-09-30 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ520300A0 (en) * 2000-01-21 2000-02-17 Novogen Research Pty Ltd Food product and process
AUPR363301A0 (en) * 2001-03-08 2001-04-05 Novogen Research Pty Ltd Dimeric isoflavones
US20050119301A1 (en) * 2001-03-16 2005-06-02 Alan Husband Treatment of restenosis
US6818668B2 (en) 2002-04-12 2004-11-16 Biotest Laboratories, Llc 5-alkyl-7-alkylcarbonate-isoflavone ester and related method
AU2003247844B2 (en) 2002-06-27 2009-01-22 The Endowment For Research In Human Biology, Inc. Compounds useful for the inhibition of ALDH
US7468445B2 (en) 2002-08-07 2008-12-23 University Of Mississippi Antigiardial agents and use thereof
US8158810B2 (en) 2006-07-27 2012-04-17 Gilead Sciences, Inc. ALDH-2 inhibitors in the treatment of addiction
TWI324514B (en) 2008-02-26 2010-05-11 Univ Kaohsiung Medical Isoflavone derivatives and pharmaceutical compositions comprising the same
TWI365071B (en) * 2008-02-26 2012-06-01 Univ Kaohsiung Medical Isoxazole derivatives and pharmaceutical compositions comprising the same
CN103145673B (zh) * 2011-12-06 2015-05-20 安徽贝克生物制药有限公司 黄豆苷元衍生物及其药学上可接受的盐

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA193010A (en) 1919-04-02 1919-09-30 Alvin A. Ritcheson Motor vehicle
CA201219A (en) 1920-06-22 Hippolyte Louis Sizaire Maurice Lubricating vehicle spring

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU162377B (ja) * 1970-05-27 1973-02-28
GB1495189A (en) * 1975-09-12 1977-12-14 Pfizer Ltd 4-oxo-4h-benzopyran derivatives and process for their preparation
GB1495305A (en) * 1975-09-12 1977-12-14 Pfizer Ltd 3-phenyl-4-oxo-4h-benzopyran derivatives
US4644012A (en) * 1983-12-21 1987-02-17 Takeda Chemical Industries, Ltd. Treatment for osteoporosis
JPS60132976A (ja) * 1983-12-21 1985-07-16 Takeda Chem Ind Ltd 新規３−フエニル−４ｈ−１−ベンゾピラン−４−オン誘導体
US5002603A (en) * 1989-12-04 1991-03-26 Board Of Trustees Operating Michigan State University Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA201219A (en) 1920-06-22 Hippolyte Louis Sizaire Maurice Lubricating vehicle spring
CA193010A (en) 1919-04-02 1919-09-30 Alvin A. Ritcheson Motor vehicle

Also Published As

Publication number Publication date
HK1003995A1 (en) 1998-11-13
LTIP779A (en) 1995-01-31
CA2058619C (en) 1999-05-04
JPH089610B2 (ja) 1996-01-31
JPH04507085A (ja) 1992-12-10
RU2036918C1 (ru) 1995-06-09
WO1991015483A1 (en) 1991-10-17
EP0478558B1 (en) 1994-02-02
CA2058619A1 (en) 1991-10-07
NO300733B1 (no) 1997-07-14
KR0149172B1 (ko) 1998-10-15
DE69006502T2 (de) 1994-05-19
NO914786L (no) 1991-12-05
US5247102A (en) 1993-09-21
DK0478558T3 (da) 1994-05-02
AU631860B2 (en) 1992-12-10
FI915741A0 (fi) 1991-12-05
DE69006502D1 (de) 1994-03-17
EP0478558A1 (en) 1992-04-08
ATE101143T1 (de) 1994-02-15
AU5427490A (en) 1991-10-30
KR920701192A (ko) 1992-08-11
NO914786D0 (no) 1991-12-05

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