LT3122B - Microbiological process for preparing malonyl-7-aminocephalosporanic acid derivatives - Google Patents

Microbiological process for preparing malonyl-7-aminocephalosporanic acid derivatives Download PDF

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Publication number
LT3122B
LT3122B LTIP499A LTIP499A LT3122B LT 3122 B LT3122 B LT 3122B LT IP499 A LTIP499 A LT IP499A LT IP499 A LTIP499 A LT IP499A LT 3122 B LT3122 B LT 3122B
Authority
LT
Lithuania
Prior art keywords
formula
malonyl
substrate
aminocephalosporanic acid
microorganisms
Prior art date
Application number
LTIP499A
Other languages
English (en)
Lithuanian (lt)
Inventor
Sabine Schurr
Andreas Tschech
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of LTIP499A publication Critical patent/LTIP499A/xx
Publication of LT3122B publication Critical patent/LT3122B/lt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D505/10—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D505/12—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 substituted in position 7
    • C07D505/14—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 substituted in position 7 with hetero atoms directly attached in position 7
    • C07D505/16—Nitrogen atoms
    • C07D505/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
LTIP499A 1992-04-29 1993-04-29 Microbiological process for preparing malonyl-7-aminocephalosporanic acid derivatives LT3122B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH138192 1992-04-29

Publications (2)

Publication Number Publication Date
LTIP499A LTIP499A (en) 1994-07-15
LT3122B true LT3122B (en) 1994-12-27

Family

ID=4209103

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP499A LT3122B (en) 1992-04-29 1993-04-29 Microbiological process for preparing malonyl-7-aminocephalosporanic acid derivatives

Country Status (11)

Country Link
US (1) US5338667A (cs)
EP (1) EP0568004A2 (cs)
JP (1) JPH0646835A (cs)
KR (1) KR930021796A (cs)
CN (1) CN1077989A (cs)
CA (1) CA2095166A1 (cs)
CZ (2) CZ280145B6 (cs)
LT (1) LT3122B (cs)
LV (1) LV10315B (cs)
MX (1) MX9302238A (cs)
TW (1) TW241265B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1065278C (zh) * 1994-08-27 2001-05-02 中国科学院上海植物生理研究所 一步两酶法制造7－氨基头孢烷酸
CA2431314C (en) 2000-12-11 2010-04-20 United States Filter Corporation Activated carbon for odor control and method for making same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06248380A (ja) 1993-02-23 1994-09-06 Mitsubishi Heavy Ind Ltd 積層型熱交換器及びその製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5170884A (en) * 1974-12-12 1976-06-18 Toyo Jozo Kk 77 amino sefuemukagobutsuno seizohoho
DK158316C (da) * 1974-01-23 1990-10-08 Toyo Jozo Kk Fremgangsmaade til fremstilling af 3-substituerede 7-amino-3-cephem-4-carboxylsyrederivater
FR2434169A2 (fr) * 1978-06-22 1980-03-21 Chinoin Gyogyszer Es Vegyeszet Nouveaux derives reactifs de l'acide penicillanique et de l'acide cephalosporanique et procede pour leur preparation
JPS6248380A (ja) * 1985-08-28 1987-03-03 Asahi Chem Ind Co Ltd セフアロスポリンｃアシラ−ゼの製造法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06248380A (ja) 1993-02-23 1994-09-06 Mitsubishi Heavy Ind Ltd 積層型熱交換器及びその製造方法

Also Published As

Publication number Publication date
EP0568004A2 (de) 1993-11-03
CZ279523B6 (cs) 1995-05-17
CA2095166A1 (en) 1993-10-30
JPH0646835A (ja) 1994-02-22
EP0568004A3 (cs) 1994-03-23
LV10315B (en) 1995-06-20
KR930021796A (ko) 1993-11-23
LV10315A (lv) 1994-10-20
CN1077989A (zh) 1993-11-03
MX9302238A (es) 1993-10-01
LTIP499A (en) 1994-07-15
US5338667A (en) 1994-08-16
CZ76393A3 (en) 1993-12-15
CZ226494A3 (en) 1995-02-15
TW241265B (cs) 1995-02-21
CZ280145B6 (cs) 1995-11-15

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Effective date: 19950429