LT1981519T - Proteazės slopinimas - Google Patents

Proteazės slopinimas

Info

Publication number
LT1981519T
LT1981519T LTEP06848187.8T LT06848187T LT1981519T LT 1981519 T LT1981519 T LT 1981519T LT 06848187 T LT06848187 T LT 06848187T LT 1981519 T LT1981519 T LT 1981519T
Authority
LT
Lithuania
Prior art keywords
protease inhibition
protease
inhibition
Prior art date
Application number
LTEP06848187.8T
Other languages
English (en)
Lithuanian (lt)
Inventor
Robert C. Ladner
Original Assignee
Dyax Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp. filed Critical Dyax Corp.
Publication of LT1981519T publication Critical patent/LT1981519T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTEP06848187.8T 2005-12-29 2006-12-27 Proteazės slopinimas LT1981519T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75490305P 2005-12-29 2005-12-29
PCT/US2006/049322 WO2007079096A2 (en) 2005-12-29 2006-12-27 Protease inhibition

Publications (1)

Publication Number Publication Date
LT1981519T true LT1981519T (lt) 2018-04-25

Family

ID=38228815

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP06848187.8T LT1981519T (lt) 2005-12-29 2006-12-27 Proteazės slopinimas

Country Status (14)

Country Link
US (1) US8828703B2 (enExample)
EP (1) EP1981519B1 (enExample)
JP (2) JP5632126B2 (enExample)
AU (1) AU2006332774A1 (enExample)
CA (1) CA2635589C (enExample)
CY (1) CY1119967T1 (enExample)
DK (1) DK1981519T3 (enExample)
ES (1) ES2663497T3 (enExample)
HU (1) HUE038243T2 (enExample)
LT (1) LT1981519T (enExample)
PL (1) PL1981519T3 (enExample)
PT (1) PT1981519T (enExample)
SI (1) SI1981519T1 (enExample)
WO (1) WO2007079096A2 (enExample)

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US20050222023A1 (en) * 2002-02-07 2005-10-06 Hans-Peter Hauser Albumin-fused kunitz domain peptides
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
PT1941867E (pt) 2002-06-07 2012-02-16 Dyax Corp Polipeptídeo contendo um domínio kunitz modificado
DK2386310T3 (en) 2002-08-28 2019-02-25 Dyax Corp Methods of preserving organs and tissues
PT1663281E (pt) * 2003-08-29 2014-03-17 Dyax Corp Inibidores de proteases poli-peguilados
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
WO2006108826A1 (en) 2005-04-15 2006-10-19 Novo Nordisk A/S Basic protein purification tags from thermophilic bacteria
WO2008043847A1 (en) 2006-10-13 2008-04-17 Novo Nordisk Health Care Ag Processing enzymes fused to basic protein tags
US20090075887A1 (en) * 2007-08-21 2009-03-19 Genzyme Corporation Treatment with Kallikrein Inhibitors
JP2010536883A (ja) * 2007-08-23 2010-12-02 ジェンザイム・コーポレーション カリクレイン阻害剤を用いた治療
WO2010048432A1 (en) * 2008-10-22 2010-04-29 Dyax Corp. Combination treatments comprising protease binding proteins for inflammatory disorders
JP2013516389A (ja) 2009-01-06 2013-05-13 ダイアックス コーポレーション カリクレイン阻害剤による粘膜炎治療
WO2010103475A2 (en) * 2009-03-10 2010-09-16 Med Discovery Sa Use of serine protease inhibitors in the treatment of neutropenia
GB0916578D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
HRP20181419T1 (hr) 2010-01-06 2018-11-16 Dyax Corp. Plazma kalikrein vezni proteini
US9597379B1 (en) * 2010-02-09 2017-03-21 David Gordon Bermudes Protease inhibitor combination with therapeutic proteins including antibodies
IL269565B2 (en) 2011-01-06 2024-06-01 Dyax Corp Plasma kallikrein binding proteins
WO2013059439A2 (en) 2011-10-21 2013-04-25 Dyax Corp. Combination therapy comprising an mmp-14 binding protein
WO2014107171A1 (en) 2013-01-07 2014-07-10 Omniox, Inc. Polymeric forms of h-nox proteins
JP6444315B2 (ja) * 2013-01-20 2018-12-26 ダイアックス コーポレーション ブラジキニン媒介障害の評価および治療
KR20250066486A (ko) 2013-10-21 2025-05-13 다케다 파머수티컬 컴패니 리미티드 혈장 칼리크레인 시스템 바이오마커를 결정하기 위한 검정법
KR102665705B1 (ko) * 2013-10-21 2024-05-14 다케다 파머수티컬 컴패니 리미티드 자가면역 질환의 진단 및 치료
ES2700149T3 (es) 2014-02-24 2019-02-14 Takeda Gmbh Proteínas de fusión de UTI
KR102555955B1 (ko) 2014-03-27 2023-07-18 다케다 파머수티컬 컴패니 리미티드 당뇨병성 황반 부종의 치료를 위한 조성물 및 방법
AU2016232866B2 (en) 2015-03-17 2021-10-21 Omniox, Inc. Modulation of tumor immunity by protein-mediated 02 delivery
EP3365685B1 (en) 2015-10-19 2020-11-25 Dyax Corp. Immunoassay to detect cleaved high molecular weight kininogen
WO2017100679A1 (en) 2015-12-11 2017-06-15 Dyax Corp. Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack
JP6467073B2 (ja) * 2018-01-04 2019-02-06 オムニオクス， インコーポレイテッド Ｈ−ｎｏｘタンパク質の重合体形態
CA3093802A1 (en) 2018-03-13 2019-09-19 Shire Human Genetic Therapies, Inc. Substituted imidazopyridines as inhibitors of plasma kallikrein and uses thereof
MX2022001812A (es) * 2019-08-12 2022-03-11 Regeneron Pharma Variantes del receptor estimulante de macrofagos 1 (mst1r) y sus usos.
CN114667289B (zh) 2019-09-18 2025-08-26 武田药品工业有限公司 杂芳基血浆激肽释放酶抑制剂
ES2987744T3 (es) 2019-09-18 2024-11-18 Takeda Pharmaceuticals Co Inhibidores de calicreína plasmática y usos de los mismos

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Also Published As

Publication number Publication date
AU2006332774A1 (en) 2007-07-12
US8828703B2 (en) 2014-09-09
SI1981519T1 (en) 2018-05-31
JP2009521926A (ja) 2009-06-11
PL1981519T3 (pl) 2018-07-31
WO2007079096A2 (en) 2007-07-12
CA2635589A1 (en) 2007-07-12
JP2012235793A (ja) 2012-12-06
EP1981519B1 (en) 2017-12-27
CA2635589C (en) 2017-01-17
DK1981519T3 (en) 2018-02-19
CY1119967T1 (el) 2018-12-12
PT1981519T (pt) 2018-02-23
ES2663497T3 (es) 2018-04-13
HUE038243T2 (hu) 2018-10-29
WO2007079096A3 (en) 2008-02-14
JP5632126B2 (ja) 2014-11-26
EP1981519A4 (en) 2010-01-06
US20080255025A1 (en) 2008-10-16
EP1981519A2 (en) 2008-10-22

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