KR970701557A - 자기면역성 질환의 치료 수단 및 치료 방법(means for treating auto-immune diseases and method of treatment) - Google Patents

자기면역성 질환의 치료 수단 및 치료 방법(means for treating auto-immune diseases and method of treatment) Download PDF

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KR970701557A
KR970701557A KR1019960705237A KR19960705237A KR970701557A KR 970701557 A KR970701557 A KR 970701557A KR 1019960705237 A KR1019960705237 A KR 1019960705237A KR 19960705237 A KR19960705237 A KR 19960705237A KR 970701557 A KR970701557 A KR 970701557A
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glucoprotein
trophoblast
treatment
treating
immune diseases
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KR1019960705237A
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KR100382252B1 (ko
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세묘노비치 타타리노프 주리
압두무슬리모비치 알리카노프 칼라
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이반 니콜라에비치 골로비스티코프
레오니드 야조노비치 카차라바
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

본 발명은 억제 면역결여를 보이는 자기번역성 질환을 치료하기 위한 수단으로서 사용되는 영양막 β-I-글루코프로테인에 관한다.
또한, 본 발명은, 단핵세포(MNC)의 TBG 민감성 시험과 관령되는 영양막 β-I-글루코프로테인(TBG)의 면역 보정제의 투여를 포함하는 자기면역성 질환의 치료방법에 관한 것이다.

Description

자기면역성 질환의 치료 수단 및 치료 방법(MEANS FOR TREATING AUTOIMMUNE DISEASES AND METHOD OF TREATMENT)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 자기면역성 질환을 치료하기 위한 수단으로서 사용되는 영양막 β-I-글루코프로테인(TBG).
  2. 면역상태를 사전연구하여, 억제자 결여가 발견되는 경우, 이어서 면역 보정제로서 영양막 β-I-글루코프로테인을 혈액 1ml당 3 내지 120㎍의 투여량으로 주입되는 것을 특징으로 하는, 면역 보정제를 주입시키는 것을 포함하는 자기면역성 질환의 치료방법.
  3. 제2항에 있어서, 영양막 β-I-글루코프로테인이 비경구적으로 주입되는 것을 특징으로 하는 방법.
  4. 제2항에 있어서, 60㎍/㎖ 농도의 영양막 β-I-글루코프로테인은 말초혈로부터 단리된 자기면역 세포와 배양되어, 정맥내로 주입되는 것을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019960705237A 1994-03-18 1995-03-16 자가면역성질환을치료하기위한약제조성물 KR100382252B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU9494008169A RU2056852C1 (ru) 1994-03-18 1994-03-18 Средство для лечения аутоиммунных заболеваний с иммунодефицитом супрессоров и способ лечения аутоиммунных заболеваний
RU94008169 1994-03-18

Publications (2)

Publication Number Publication Date
KR970701557A true KR970701557A (ko) 1997-04-12
KR100382252B1 KR100382252B1 (ko) 2003-07-07

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KR1019960705237A KR100382252B1 (ko) 1994-03-18 1995-03-16 자가면역성질환을치료하기위한약제조성물

Country Status (22)

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US (1) US6150326A (ko)
EP (1) EP0790059B1 (ko)
JP (1) JPH09510473A (ko)
KR (1) KR100382252B1 (ko)
CN (1) CN1146156A (ko)
AT (1) ATE260111T1 (ko)
AU (1) AU699896B2 (ko)
BG (1) BG62759B1 (ko)
CA (1) CA2185892A1 (ko)
CZ (1) CZ285856B6 (ko)
DE (2) DE790059T1 (ko)
ES (1) ES2107980T1 (ko)
FI (1) FI963671A (ko)
GE (1) GEP20012377B (ko)
GR (1) GR980300023T1 (ko)
HU (1) HUT75720A (ko)
NO (1) NO963911L (ko)
PL (1) PL179765B1 (ko)
RU (1) RU2056852C1 (ko)
SK (1) SK281948B6 (ko)
UA (1) UA26939C2 (ko)
WO (1) WO1995025531A1 (ko)

Families Citing this family (3)

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Publication number Priority date Publication date Assignee Title
GB0030729D0 (en) * 2000-12-16 2001-01-31 Univ Nottingham Substituted-4-Quinolones
CA2501940A1 (en) * 2002-10-09 2004-04-22 Tolerrx, Inc. Molecules preferentially associated with effector t cells or regulatory t cells and methods of their use
RU2303995C1 (ru) * 2006-04-28 2007-08-10 Халлар Абдумуслимович Алиханов Средство, обладающее иммунорегуляторным свойством и его применение для лечения аутоиммунных заболеваний

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Publication number Priority date Publication date Assignee Title
JPS5470384A (en) * 1977-08-22 1979-06-06 Inst Obu Kiyansaa Risaachi Roi High molecular complex
JPS61186322A (ja) * 1985-02-13 1986-08-20 Nippon Univ 免疾調節剤
IT1188646B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante
US4803072A (en) * 1986-09-10 1989-02-07 Smithkline Beckman Corporation Immunomodulation
FR2609632B1 (fr) * 1987-01-21 1991-03-29 Shelly Marc Nouvelle application therapeutique de la 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinon-6-one et les compositions pharmaceutiques destinees a cet usage
US5169835A (en) * 1989-01-18 1992-12-08 Oklahoma Medical Research Foundation Pregancy specific proteins applications
FR2650183A1 (fr) * 1989-07-25 1991-02-01 Pasteur Institut Proteines immunostimulantes, anticorps monoclonaux et polyclonaux correspondants, hybridomes correspondants et application de ces produits a des fins therapeutiques et de diagnostic
US5118669A (en) * 1989-09-20 1992-06-02 Hitachi Chemical Co., Ltd. Peptides and intermediates therefor useful as antiallergic agents, vasodilators and immunoregulators
US5559097A (en) * 1990-01-12 1996-09-24 Idaho Research Foundation, Inc. Use of a pregnancy specific protein as an immunosuppressive
RU1836957C (ru) * 1990-03-25 1993-08-30 2-й Московский государственный медицинский институт им.Н.И.Пирогова Способ получени трофобластического бета @ -гликопротеина
GB2251186A (en) * 1990-12-04 1992-07-01 Randall Neal Gatz Polypeptide for use in treatment of autoimmune disease

Also Published As

Publication number Publication date
BG62759B1 (bg) 2000-07-31
WO1995025531A1 (fr) 1995-09-28
RU2056852C1 (ru) 1996-03-27
KR100382252B1 (ko) 2003-07-07
US6150326A (en) 2000-11-21
SK118796A3 (en) 1997-06-04
AU699896B2 (en) 1998-12-17
CN1146156A (zh) 1997-03-26
ATE260111T1 (de) 2004-03-15
PL179765B1 (pl) 2000-10-31
DE69532611D1 (de) 2004-04-01
FI963671A0 (fi) 1996-09-17
AU2087495A (en) 1995-10-09
NO963911D0 (no) 1996-09-18
BG100921A (en) 1997-12-30
GEP20012377B (en) 2001-03-25
PL316311A1 (en) 1997-01-06
EP0790059A1 (en) 1997-08-20
DE790059T1 (de) 1998-03-12
JPH09510473A (ja) 1997-10-21
CZ285856B6 (cs) 1999-11-17
NO963911L (no) 1996-11-08
HUT75720A (en) 1997-05-28
GR980300023T1 (en) 1998-04-30
UA26939C2 (uk) 1999-12-29
ES2107980T1 (es) 1997-12-16
EP0790059B1 (en) 2004-02-25
CZ274796A3 (en) 1997-06-11
HU9602558D0 (en) 1996-11-28
SK281948B6 (sk) 2001-09-11
EP0790059A4 (en) 2000-11-02
FI963671A (fi) 1996-11-14
CA2185892A1 (en) 1995-09-28

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