KR970015473A - 미생물의 불활성화·파괴방법 - Google Patents

미생물의 불활성화·파괴방법 Download PDF

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KR970015473A
KR970015473A KR1019950066743A KR19950066743A KR970015473A KR 970015473 A KR970015473 A KR 970015473A KR 1019950066743 A KR1019950066743 A KR 1019950066743A KR 19950066743 A KR19950066743 A KR 19950066743A KR 970015473 A KR970015473 A KR 970015473A
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microorganisms
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electrical energy
microbial cells
cell
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간지 요시다
데루아끼 스미오가
흐우 하이타오
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나까바야시 이구다가
가부시끼가이샤 리모델링 트웬티 원
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    • C02F1/46—Treatment of water, waste water, or sewage by electrochemical methods
    • C02F1/461—Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
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    • C02F1/46—Treatment of water, waste water, or sewage by electrochemical methods
    • C02F1/461—Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
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    • C02F2303/00—Specific treatment goals
    • C02F2303/04—Disinfection

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Abstract

본 발명은 미생물의 보다 유효한 불활성화 · 파괴방법을 제공한다. 미생물에 전기에너지를 가지는 액체, 기체 또는 고체를 개입하여 전기에너지를 부여하는 것에 의해 미생물이 갖는 세포 내외의 정전용량한계를 초과하여 그 전하를 상승시켜 미생물 세포에 불가역변화를 일으키거나 및/또는 미생물 세포의 경계막을 폭열적으로 파괴시킨다.

Description

미생물의 불활성화 · 파괴방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (11)

  1. 미생물에, 전기에너지를 가지는 액체, 기체 또는 고체를 개입하여 전기에너지를 부여하는 것에 의해 미생물이 갖는 세포 내외의 정전용량한계를 초과하여 그 전하를 상승시키고 미생물 세포에 불가역변화를 일으키거나 및/또는 미생물 세포의 경계막을 폭열적으로 파괴시키는 미생물의 불활성화ㆍ파괴방법.
  2. 미생물에, 전기에너지를 가지는 액체, 기체 또는 고체를 개입하여 전기에너지를 부여하는 것에 의해 미생물의 세포 내외의 투수를 촉진시켜, 미생물 세포에 불가역변화를 일으키거나 및/또는 미생물 세포의 경계막을 폭열적으로 파괴시키는 미생물의 불활성화ㆍ파괴방법.
  3. 미생물에, 전기에너지를 가지는 액체, 기체 또는 고체를 개입하여 전기에너지를 부여하는 것에 의해 미생물이 갖는 세포 내외의 정전용량한계를 초과하여 그 전하를 상승시키고, 또한 미생물 세포 내외의 투수를 촉진시켜서 미생물 세포에 불가역변화를 일으키거나 및/또는 미생물 세포의 경계막을 폭열적으로 파괴시키는 미생물의 불활성화ㆍ파괴방법.
  4. 전기에너지를 가지는 액체가 전하수이고 그 전하 수용액중에 미생물을 배합하여 전기에너지를 부여하는 제1항 내지 제3항의 어느 한 항에 기재한 미생물의 불활성화ㆍ파괴방법.
  5. 전하수가, 하전수, 축전수, 기능수, 전기분해처리수, 강산화전위수, 강산성 전해생성 수용액, 전리수, 비전리수 또는 대전수의 어느 하나인 제4항에 기재되어 있는 미생물의 불활성화ㆍ파괴방법.
  6. 전기에너지를 가지는 기체가 전하를 가지는 기체인 제1항 내지 제3항의 어느 한 항에 기재한 미생물의 불활성화ㆍ파괴방법.
  7. 전기에너지를 가지는 고체가 축전체인 제1항 내지 제3항의 어느 한 항에 기재한 미생물의 불활성화ㆍ파괴방법.
  8. 미생물을 포함하는 액체에 전극을 개입하여 통전하고, 전극에 대하여 비접촉상태의 미생물에 전기에너지를 부여하는 것에 의해 미생물이 갖는 세포 내외의 정전용량한계를 초과하여 그 전하를 상승시키고, 미생물세포에 불가역변화를 일으키거나 및/또는 미생물 세포의 경계막을 폭열적으로 파괴시키는 미생물의 불활성화ㆍ파괴방법.
  9. 미생물을 포함하는 액체에 전극을 개입하여 통전하고, 전극에 대하여 비접촉상태의 미생물에 전기에너지를 부여하는 것에 의해 미생물의 세포 내외의 투수를 촉진시켜 미생물 세포에 불가역변화를 일으키거나 및/또는 미생물 세포의 경계막을 폭열적으로 파괴시키는 미생물의 불활성화ㆍ파괴방법.
  10. 미생물을 포함하는 액체에 전극을 개입하여 통전하고 전극에 대하여 비접촉상태의 미생물에 전기에너지를 부여하는 것에 의해 미생물이 갖는 세포 내외의 정전용량한계를 초과하여 그 전하를 상승시키고, 또한 미생물 세포 내외의 투수를 촉진시켜 미생물 세포에 불가역변화를 일으키거나 및/또는 미생물 세포의 경계막을 폭열적으로 파괴시키는 미생물의 불활성화ㆍ파괴방법.
  11. 통전이 전매성 통전이거나 또는 비전매성 통전인 제8항 내지 제10항의 어느 한 항에 기재된 미생물의 불활성화ㆍ파괴방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950066743A 1995-09-28 1995-12-29 미생물의 불활성화·파괴방법 KR970015473A (ko)

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JP7-251623 1995-09-08
JP7251623A JPH0994288A (ja) 1995-09-28 1995-09-28 微生物の不活化・破壊方法

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US (1) US5922209A (ko)
EP (1) EP0765843A1 (ko)
JP (1) JPH0994288A (ko)
KR (1) KR970015473A (ko)
CN (1) CN1146489A (ko)
AR (1) AR000805A1 (ko)
AU (1) AU694292B2 (ko)
BR (1) BR9600285A (ko)
CA (1) CA2166855C (ko)
CZ (1) CZ30996A3 (ko)
FI (1) FI960193A (ko)
HU (1) HUP9602683A2 (ko)
IL (1) IL116812A0 (ko)
MA (1) MA23790A1 (ko)
MX (1) MX9600439A (ko)
NO (1) NO960242L (ko)
NZ (1) NZ280785A (ko)
PE (1) PE26297A1 (ko)
PL (1) PL313858A1 (ko)
RU (1) RU2108113C1 (ko)
SG (1) SG48713A1 (ko)
TW (1) TW393446B (ko)
ZA (1) ZA96407B (ko)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763957B1 (fr) * 1997-05-29 2001-09-14 Bio Merieux Procede pour isoler un materiel intracellulaire et procede de traitement d'un materiel nucleique
AU2003206513A1 (en) * 2002-02-12 2003-09-04 Les Technologies Elcotech Inc. Method for the treatment of slurries by the combined action of pressure and electro-osmosis
AU2003287814A1 (en) * 2002-11-29 2004-06-23 Les Technologies Elcotech Inc. Apparatus and method for wastewater treatment by means of electroflotation and/or electrocoagulation
CA2437245A1 (fr) * 2003-08-11 2005-02-11 Les Technologies Elcotech Inc. Appareil permettant le traitement des boues a forte siccitee
US20100276294A1 (en) * 2003-03-28 2010-11-04 Lambie John M Electrolytic sanitization of water
NO327633B1 (no) * 2003-11-04 2009-09-07 Environmental Solutions As Fremgangsmate, anlegg samt komponent behandling av ballastvann.
US7959780B2 (en) 2004-07-26 2011-06-14 Emporia Capital Funding Llc Textured ion exchange membranes
US7780833B2 (en) 2005-07-26 2010-08-24 John Hawkins Electrochemical ion exchange with textured membranes and cartridge
EP1945577A1 (en) 2005-10-06 2008-07-23 Pionetics, Inc. Electrochemical ion exchange treatment of fluids
US20100072059A1 (en) * 2008-09-25 2010-03-25 Peters Michael J Electrolytic System and Method for Enhanced Radiological, Nuclear, and Industrial Decontamination
CN104058561A (zh) * 2013-03-22 2014-09-24 上海易昆机械工程有限公司 一种细胞破解器
US20140295038A1 (en) 2013-03-27 2014-10-02 Bnr Technology Development, Llc Method for extending the shelf life of liquid comestibles
US9757695B2 (en) 2015-01-03 2017-09-12 Pionetics Corporation Anti-scale electrochemical apparatus with water-splitting ion exchange membrane
CN110491678A (zh) * 2018-05-14 2019-11-22 深圳市中科摩方科技有限公司 一种表面超电容修饰的材料及其制备方法和应用
CN109908035A (zh) * 2019-04-25 2019-06-21 山西纳安生物科技有限公司 一种基于牡丹籽油的祛斑面膜
CN112556078A (zh) * 2020-11-11 2021-03-26 山东青洁能环保有限公司 感应正静电超低容量雾化电位水消毒除臭方法及设备
US11191977B1 (en) 2020-11-12 2021-12-07 Howard Letovsky Applications of bioactive frequencies and menus thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3366564A (en) * 1965-02-02 1968-01-30 Gen Electric Electrohydraulic process
US3943044A (en) * 1971-09-07 1976-03-09 Diamond Shamrock Corporation Method for treating sewage water
DE2246955C3 (de) * 1972-09-25 1980-10-02 Krautkraemer, Gmbh, 5000 Koeln Ultraschall-Meßverfahren zur Bestimmung von Wanddicken
US3925176A (en) * 1973-10-10 1975-12-09 Adolph P Okert Apparatus and method for electrolytic sewage treatment
US4012310A (en) * 1975-09-11 1977-03-15 Progressive Equipment Corporation Electrostatic water treatment system
US4305390A (en) * 1975-11-28 1981-12-15 Massachusetts Institute Of Technology Method for generating oxygen in an excited electronic state and inactivation of microorganisms
DE2643213C2 (de) * 1976-09-25 1985-02-21 Bayer Ag, 5090 Leverkusen Verfahren zum Abschwächen oder Inaktivieren von Mikroorganismen
US4179347A (en) * 1978-02-28 1979-12-18 Omnipure, Inc. System for electrocatalytic treatment of waste water streams
DE2815030A1 (de) * 1978-04-07 1979-10-18 Hoechst Ag Verfahren zur anreicherung von biomasse
JPS5939143B2 (ja) * 1981-12-12 1984-09-21 株式会社巴商会 プラズマ滅菌法
DE3233282A1 (de) * 1982-09-08 1984-03-08 Friedhelm Dr.-Ing. 5300 Bonn Caspers Keiminaktivierung ueber elektromagnetische hochfrequenzenergie
JPS6176160A (ja) * 1984-09-21 1986-04-18 松永　是 殺細胞方法
US5048404A (en) * 1985-05-31 1991-09-17 Foodco Corporation High pulsed voltage systems for extending the shelf life of pumpable food products
JPS6382666A (ja) * 1986-09-26 1988-04-13 三菱重工業株式会社 高電圧パルスによる殺菌装置
JPS647964A (en) * 1987-06-30 1989-01-11 Toshiba Corp Air cleaner and air conditioner equipped with this cleaner
US4970154A (en) * 1987-10-09 1990-11-13 Baylor College Of Medicine Method for inserting foreign genes into cells using pulsed radiofrequency
US5091152A (en) * 1988-05-19 1992-02-25 Thomas Sr Tim L Apparatus for electrically destroying targeted organisms in fluids
JPH078768B2 (ja) * 1988-06-06 1995-02-01 ジプコム株式会社 殺菌水
JPH02172467A (ja) * 1988-12-27 1990-07-04 Amosu:Kk 抗菌性セラミックス材料とその製造および使用方法
JP2651740B2 (ja) * 1990-07-26 1997-09-10 ハウス食品株式会社 高電圧パルスによる殺菌方法
US5308507A (en) * 1992-08-04 1994-05-03 Los Alamos Technical Associates, Inc. Method and apparatus for removing organic contaminants
JP2649133B2 (ja) * 1993-02-15 1997-09-03 賢士 宍戸 レジオネラ属菌殺菌除去用濾過装置
NZ264188A (en) * 1994-08-05 1996-10-28 Ennotech Holdings Ltd Method and apparatus for sterilising electrically conductive liquid by creating a voltage gradient between electrodes in contact with the liquid
US5635059A (en) * 1994-10-20 1997-06-03 Aqua-Ion Systems, Inc. Method and apparatus for water treatment and purification using gas ion plasma source and disinfectant metal ion complexes
US5695650A (en) * 1995-11-02 1997-12-09 Held; Jeffery S. Method for dewatering previously-dewatered municipal waste-water sludges using high electrical voltage

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IL116812A0 (en) 1996-05-14
AU4083096A (en) 1997-04-10
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CA2166855C (en) 1999-01-19
SG48713A1 (en) 1998-05-18
AU694292B2 (en) 1998-07-16
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EP0765843A1 (en) 1997-04-02
FI960193A0 (fi) 1996-01-15
TW393446B (en) 2000-06-11
HUP9602683A2 (en) 1997-06-30
JPH0994288A (ja) 1997-04-08
ZA96407B (en) 1997-01-20
NO960242L (no) 1997-04-01
NO960242D0 (no) 1996-01-19
HU9602683D0 (en) 1996-11-28
RU2108113C1 (ru) 1998-04-10
FI960193A (fi) 1997-03-29
CN1146489A (zh) 1997-04-02
MA23790A1 (fr) 1996-10-01
CZ30996A3 (cs) 1998-03-18
BR9600285A (pt) 1997-12-23
PL313858A1 (en) 1997-04-01
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US5922209A (en) 1999-07-13
AR000805A1 (es) 1997-08-06

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