KR970002917B1 - 인터루킨-i 억제제 - Google Patents

인터루킨-i 억제제 Download PDF

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Publication number
KR970002917B1
KR970002917B1 KR1019960703435A KR19960703435A KR970002917B1 KR 970002917 B1 KR970002917 B1 KR 970002917B1 KR 1019960703435 A KR1019960703435 A KR 1019960703435A KR 19960703435 A KR19960703435 A KR 19960703435A KR 970002917 B1 KR970002917 B1 KR 970002917B1
Authority
KR
South Korea
Prior art keywords
dna sequence
dna
inhibitor
sequence
vector
Prior art date
Application number
KR1019960703435A
Other languages
English (en)
Korean (ko)
Inventor
에이취. 하논 챨스
피. 아이젠버그 스티븐
씨. 톰슨 로버트
피. 아렌드 윌리암
지. 조슬린 페니크
소머 안드레아스
Original Assignee
씨네겐 인코포레이티드
그래고리 비. 아보트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 씨네겐 인코포레이티드, 그래고리 비. 아보트 filed Critical 씨네겐 인코포레이티드
Priority claimed from KR1019890702466A external-priority patent/KR0148009B1/ko
Application granted granted Critical
Publication of KR970002917B1 publication Critical patent/KR970002917B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019960703435A 1988-05-27 1989-05-25 인터루킨-i 억제제 KR970002917B1 (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US19991588A 1988-05-27 1988-05-27
US199,915 1988-05-27
US23871388A 1988-08-31 1988-08-31
US238,713 1988-08-31
US26653188A 1988-11-03 1988-11-03
US266,531 1988-11-13
PCT/US1989/002275 WO1989011540A1 (en) 1988-05-27 1989-05-25 Interleukin-1 inhibitors
KR1019890702466A KR0148009B1 (ko) 1988-05-27 1989-05-25 인터루킨-1 억제제

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1019890702466A Division KR0148009B1 (ko) 1988-05-27 1989-05-25 인터루킨-1 억제제

Publications (1)

Publication Number Publication Date
KR970002917B1 true KR970002917B1 (ko) 1997-03-12

Family

ID=27394086

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960703435A KR970002917B1 (ko) 1988-05-27 1989-05-25 인터루킨-i 억제제

Country Status (9)

Country Link
JP (2) JP3192651B2 (fi)
KR (1) KR970002917B1 (fi)
BR (1) BR8907457A (fi)
DK (1) DK172763B1 (fi)
FI (2) FI109206B (fi)
HU (3) HU215434B (fi)
NO (2) NO316122B1 (fi)
OA (1) OA09631A (fi)
WO (1) WO1989011540A1 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075222A (en) 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
US6159460A (en) * 1988-05-27 2000-12-12 Amgen Inc. Method for treating interleukin-1 mediated diseases
US6858409B1 (en) 1988-05-27 2005-02-22 Amgen Inc. Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
US5872095A (en) * 1990-05-01 1999-02-16 Chiron Corporation IL-1 receptor antagonists medicaments
AU655766B2 (en) * 1990-05-01 1995-01-12 Chiron Corporation Interleukin-1 antagonist and uses thereof
US5932537A (en) * 1990-10-09 1999-08-03 Chiron Corporation Method for attenuating a cellular response to IL-1
US5747444A (en) * 1990-10-09 1998-05-05 Chiron Corporation Method of treating graft-versus-host disease
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
US20030103978A1 (en) 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
US20060067938A1 (en) * 2001-10-26 2006-03-30 Sherif Daouti Methods for the treatment of osteoarthritis and compositions thereof
MXPA04009681A (es) 2002-04-05 2005-01-11 Amgen Inc Anticuerpos humanos neutralizantes anti-ligando de osteoprotegerina como inhibidores selectivos de la ruta del ligando de osteoprotegerina.
AU2005267722B2 (en) 2004-08-04 2009-10-08 Amgen Inc. Antibodies to Dkk-1
PT2188313T (pt) 2007-08-21 2017-12-12 Amgen Inc Proteínas de ligação ao antigénio c-fms humano
US8242074B2 (en) * 2008-09-12 2012-08-14 Xbiotech, Inc. Modulation of the amount or function of pathogenic CD14+CD16+ monocytes
WO2012025910A1 (en) 2010-08-26 2012-03-01 Centro De Investigación Y De Estudios Avanzados Del Instituto Politécnico Nacional METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOARTHRITIS AT EARLY STAGES USING INTERLEUKIN IL-1ß AS EARLY BIOMARKER OF THE DISEASE
RU2013145283A (ru) 2011-03-14 2015-04-20 Флого АпС Новые антагонисты рецептора интерлейкина-1
CN103492416A (zh) 2011-04-15 2014-01-01 默克专利股份公司 用于癌症中使用的抗il-1r1抑制剂
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
WO2015087187A1 (en) 2013-12-10 2015-06-18 Rinat Neuroscience Corp. Anti-sclerostin antibodies
JP6976265B2 (ja) 2016-03-08 2021-12-08 ヤンセン バイオテツク，インコーポレーテツド Ｇｉｔｒ抗体、方法、及び使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2220662A (en) * 1987-08-26 1990-01-17 Biogen Inc Biological materials,processes for producing biological materials and for using such materials in therapy

Also Published As

Publication number Publication date
HU893412D0 (en) 1991-05-28
NO316122B1 (no) 2003-12-15
HU215434B (hu) 1999-04-28
FI109206B (fi) 2002-06-14
NO905090D0 (no) 1990-11-23
DK8591A (da) 1991-01-18
BR8907457A (pt) 1991-04-02
FI905812A0 (fi) 1990-11-26
JP3192651B2 (ja) 2001-07-30
WO1989011540A1 (en) 1989-11-30
AU633831B2 (en) 1993-02-11
HU9803037D0 (en) 1999-11-29
FI20020545A (fi) 2002-03-21
OA09631A (en) 1993-04-30
JP2001029093A (ja) 2001-02-06
NO20014783D0 (no) 2001-10-01
DK8591D0 (da) 1991-01-18
NO316917B1 (no) 2004-06-21
NO905090L (no) 1991-01-28
HU222810B1 (hu) 2003-11-28
AU3746989A (en) 1989-12-12
NO20014783L (no) 1991-01-28
JPH03505279A (ja) 1991-11-21
DK172763B1 (da) 1999-07-05

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