FI20020545A - Eristetty DNA-molekyyli, joka koodaa interleukiini-1 inhibiittoria, sitä sisältävä vektori ja isäntäsolu, menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi sekä niiden käyttö farmaseuttistenkoostumusten valmistamisessa - Google Patents

Eristetty DNA-molekyyli, joka koodaa interleukiini-1 inhibiittoria, sitä sisältävä vektori ja isäntäsolu, menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi sekä niiden käyttö farmaseuttistenkoostumusten valmistamisessa Download PDF

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Publication number
FI20020545A
FI20020545A FI20020545A FI20020545A FI20020545A FI 20020545 A FI20020545 A FI 20020545A FI 20020545 A FI20020545 A FI 20020545A FI 20020545 A FI20020545 A FI 20020545A FI 20020545 A FI20020545 A FI 20020545A
Authority
FI
Finland
Prior art keywords
interleukin
inhibitors
inhibitor
vector
preparation
Prior art date
Application number
FI20020545A
Other languages
English (en)
Swedish (sv)
Inventor
Charles H Hannum
Stephen P Eisenberg
Robert C Thompson
William P Arend
Fenneke G Joslin
Andreas Sommer
Original Assignee
Amgen Inc
Univ Colorado Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc, Univ Colorado Foundation filed Critical Amgen Inc
Publication of FI20020545A publication Critical patent/FI20020545A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI20020545A 1988-05-27 2002-03-21 Eristetty DNA-molekyyli, joka koodaa interleukiini-1 inhibiittoria, sitä sisältävä vektori ja isäntäsolu, menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi sekä niiden käyttö farmaseuttistenkoostumusten valmistamisessa FI20020545A (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19991588A 1988-05-27 1988-05-27
US23871388A 1988-08-31 1988-08-31
US26653188A 1988-11-03 1988-11-03
PCT/US1989/002275 WO1989011540A1 (en) 1988-05-27 1989-05-25 Interleukin-1 inhibitors

Publications (1)

Publication Number Publication Date
FI20020545A true FI20020545A (fi) 2002-03-21

Family

ID=27394086

Family Applications (2)

Application Number Title Priority Date Filing Date
FI905812A FI109206B (fi) 1988-05-27 1990-11-26 Interleukiini-1 inhibiittoreita koodittavat DNA-sekvenssit, niitä sisältävät vektorit ja isäntäsolut sekä menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi
FI20020545A FI20020545A (fi) 1988-05-27 2002-03-21 Eristetty DNA-molekyyli, joka koodaa interleukiini-1 inhibiittoria, sitä sisältävä vektori ja isäntäsolu, menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi sekä niiden käyttö farmaseuttistenkoostumusten valmistamisessa

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI905812A FI109206B (fi) 1988-05-27 1990-11-26 Interleukiini-1 inhibiittoreita koodittavat DNA-sekvenssit, niitä sisältävät vektorit ja isäntäsolut sekä menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi

Country Status (9)

Country Link
JP (2) JP3192651B2 (fi)
KR (1) KR970002917B1 (fi)
BR (1) BR8907457A (fi)
DK (1) DK172763B1 (fi)
FI (2) FI109206B (fi)
HU (3) HU215434B (fi)
NO (2) NO316122B1 (fi)
OA (1) OA09631A (fi)
WO (1) WO1989011540A1 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159460A (en) * 1988-05-27 2000-12-12 Amgen Inc. Method for treating interleukin-1 mediated diseases
US6858409B1 (en) 1988-05-27 2005-02-22 Amgen Inc. Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
US5075222A (en) 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
DE69131044T2 (de) * 1990-05-01 1999-11-18 Chiron Corp Interleukin-i antagonist und seine verwendung
US5872095A (en) * 1990-05-01 1999-02-16 Chiron Corporation IL-1 receptor antagonists medicaments
US5840496A (en) * 1990-10-09 1998-11-24 Chiron Corporation Method for diagnosing endometrial cancer
US5932537A (en) * 1990-10-09 1999-08-03 Chiron Corporation Method for attenuating a cellular response to IL-1
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
US20030103978A1 (en) 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
EP1442132A2 (en) * 2001-10-26 2004-08-04 Novartis AG Methods for the treatment of osteoarthritis and compositions thereof
JP4761710B2 (ja) 2002-04-05 2011-08-31 アムジェン インコーポレイテッド 選択的ｏｐｇｌ経路インヒビターとしてのヒト抗ｏｐｇｌ中和抗体
US7709611B2 (en) 2004-08-04 2010-05-04 Amgen Inc. Antibodies to Dkk-1
CA2696761C (en) 2007-08-21 2017-02-14 Amgen Inc. Human c-fms antigen binding proteins
WO2010030979A2 (en) * 2008-09-12 2010-03-18 Xbiotech, Inc. Targeting pathogenic monocytes
WO2012025910A1 (en) 2010-08-26 2012-03-01 Centro De Investigación Y De Estudios Avanzados Del Instituto Politécnico Nacional METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOARTHRITIS AT EARLY STAGES USING INTERLEUKIN IL-1ß AS EARLY BIOMARKER OF THE DISEASE
RU2013145283A (ru) 2011-03-14 2015-04-20 Флого АпС Новые антагонисты рецептора интерлейкина-1
US20140308294A1 (en) 2011-04-15 2014-10-16 Merck Patent Gmbh Anti-IL-1R1 Inhibitors For Use in Cancer
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
WO2015087187A1 (en) 2013-12-10 2015-06-18 Rinat Neuroscience Corp. Anti-sclerostin antibodies
BR112018068103A2 (pt) 2016-03-08 2019-01-15 Janssen Biotech Inc anticorpos gitr, métodos e usos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0138654B1 (ko) * 1987-08-26 1998-04-30 프레드릭 에이. 유스티스, 3세 인터루킨-i 저해제 및 이의 제조방법

Also Published As

Publication number Publication date
HU893412D0 (en) 1991-05-28
NO905090D0 (no) 1990-11-23
JP2001029093A (ja) 2001-02-06
KR970002917B1 (ko) 1997-03-12
JPH03505279A (ja) 1991-11-21
NO905090L (no) 1991-01-28
JP3192651B2 (ja) 2001-07-30
DK172763B1 (da) 1999-07-05
NO316122B1 (no) 2003-12-15
DK8591D0 (da) 1991-01-18
FI109206B (fi) 2002-06-14
HU222810B1 (hu) 2003-11-28
HU9803037D0 (en) 1999-11-29
NO20014783L (no) 1991-01-28
FI905812A0 (fi) 1990-11-26
AU633831B2 (en) 1993-02-11
NO316917B1 (no) 2004-06-21
DK8591A (da) 1991-01-18
AU3746989A (en) 1989-12-12
HU215434B (hu) 1999-04-28
OA09631A (en) 1993-04-30
NO20014783D0 (no) 2001-10-01
WO1989011540A1 (en) 1989-11-30
BR8907457A (pt) 1991-04-02

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