KR960022971A - 들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법 - Google Patents

들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법 Download PDF

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Publication number
KR960022971A
KR960022971A KR1019940033544A KR19940033544A KR960022971A KR 960022971 A KR960022971 A KR 960022971A KR 1019940033544 A KR1019940033544 A KR 1019940033544A KR 19940033544 A KR19940033544 A KR 19940033544A KR 960022971 A KR960022971 A KR 960022971A
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KR
South Korea
Prior art keywords
linolenic acid
perilla oil
separating
acetone
purifying
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KR1019940033544A
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English (en)
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KR970002037B1 (ko
Inventor
이정일
류수노
허한순
정보영
Original Assignee
김광희
농촌진흥청
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Application filed by 김광희, 농촌진흥청 filed Critical 김광희
Priority to KR1019940033544A priority Critical patent/KR970002037B1/ko
Priority to US08/512,829 priority patent/US5672726A/en
Priority to JP7277402A priority patent/JP2819455B2/ja
Publication of KR960022971A publication Critical patent/KR960022971A/ko
Application granted granted Critical
Publication of KR970002037B1 publication Critical patent/KR970002037B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08—Refining
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/007—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids using organic solvents
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)

Abstract

본 발명은 들깨유로부터 α-리놀렌산을 고순도로 분리, 정제하는 방법에 관한 것으로, 더욱 상세하게는, 질산은(AgNO3) 함침 실리카겔을 사용하고, 용리액으로서 아세톤-헥산 혼합 용매제를 사용한 순상분배 크로마토그래피를 이용함을 특징으로 하는 α-리놀렌산의 분리, 정제 방법에 관한 것이다.

Description

들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 들깨유지방산 혼합물로부터 α-리놀렌산을 분리, 정제함에 있어서, 질산은 (AgNO3) 함침 실리카겔을 담체로 하고, 아세톤-헥산 혼합 용매계를 용리액으로 한 크로마토그래피법을 이용함을 특징으로 하는 고순도 α-리놀렌산의 분리, 정제 방법.
  2. 제1항에 있어서, 들깨유지방산 혼합물은 들깨유를 가수분해하여 얻은 지방산 혼합물이거나 이를 저온 분별 결정법으로 농축한 것임을 특징으로 하는 고순돈 α-리놀렌산의 분리, 정제방법.
  3. 제1항에 있어서, 들깨유지방산 혼합물은 담체 100g당 2∼3g의 양으로 컬럼에 주입함으로 특징으로 하는 고순도 α-리놀렌산의 분리, 정제 방법.
  4. 제1항에 있어서, 질산은 함침 실리카겔은 70∼230메쉬의 실리카겔 100g당 질산은 10g을 함침시킨 것임을 특징으로 하는 고순도 α-리놀렌산의 분리, 정제 방법.
  5. 제1항에 있어서, 용리액으로 아세톤 : 헥산의 부피비가 2 : 98, 5 : 95, 7 : 93인 아세톤-헥산 혼합 용매계를 연속적으로 적용한 것임을 특징으로 하는 고순도 α-리놀렌산의 분리, 정제 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940033544A 1994-12-09 1994-12-09 들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법 KR970002037B1 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1019940033544A KR970002037B1 (ko) 1994-12-09 1994-12-09 들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법
US08/512,829 US5672726A (en) 1994-12-09 1995-08-09 Method for separating and purifying α-linolenic acid from perilla oil
JP7277402A JP2819455B2 (ja) 1994-12-09 1995-10-25 α−リノレン酸の分離精製方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019940033544A KR970002037B1 (ko) 1994-12-09 1994-12-09 들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법

Publications (2)

Publication Number Publication Date
KR960022971A true KR960022971A (ko) 1996-07-18
KR970002037B1 KR970002037B1 (ko) 1997-02-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940033544A KR970002037B1 (ko) 1994-12-09 1994-12-09 들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법

Country Status (3)

Country Link
US (1) US5672726A (ko)
JP (1) JP2819455B2 (ko)
KR (1) KR970002037B1 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000050547A1 (en) 1999-02-26 2000-08-31 Monsanto Company Process for separating a triglyceride comprising a docosahexaenoic acid residue from a mixture of triglycerides
BR0011597B1 (pt) * 1999-05-25 2011-03-22 método para separar um composto de alto peso molecular contendo lactona.
US6340705B1 (en) * 1999-09-10 2002-01-22 Monsanto Technology, Llc Use of α-linolenic acid metabolites for treatment or prevention of cancer
CN1095824C (zh) * 2000-04-13 2002-12-11 胡德甫 一种高纯度α－亚麻酸的制备方法
CA2436650A1 (en) * 2003-08-06 2005-02-06 Naturia Inc. Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses
EP1786915A1 (en) * 2004-09-10 2007-05-23 Ivax Pharmaceuticals S.R.O. Process for isolation of crystalline tacrolimus
BRPI0515699A (pt) * 2004-09-10 2008-07-29 Ivax Pharmaceuticals Sro processo para isolamento de compostos de macrolido
BRPI0620310B1 (pt) * 2005-12-16 2017-12-05 Archer-Daniels-Midland Company A method for preparing a composition enriched in compounds containing unsaturated carbon chains by simulated moving bed chromatography using an adsorbent containing silver ions
CN100363326C (zh) * 2005-12-30 2008-01-23 安阳化学工业集团有限责任公司 纯度大于80%的α-亚麻酸的生产工艺
JP4918259B2 (ja) * 2006-01-06 2012-04-18 株式会社キャタラー 低分子有機ガス吸収材及びこれを用いた燃料蒸気処理装置
CN101624345B (zh) * 2009-08-06 2013-04-17 浙江工业大学 一种从蚕蛹油中提取高纯度的α-亚麻酸乙酯的方法
ES2363518B1 (es) * 2010-01-23 2012-06-13 Universidad De Almería Procedimiento para la purificación de trigliceridos que contienen ácido estearidónico en posición sn-2.
JP6364538B2 (ja) * 2016-12-22 2018-07-25 花王株式会社 油脂組成物
KR101985683B1 (ko) * 2017-02-09 2019-06-04 농업회사법인 서우하 주식회사 식물성 유지로부터 알파-리놀렌산 농축 방법
EP3586640A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586642A1 (en) * 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions
CN110054560A (zh) * 2019-05-23 2019-07-26 河南农业大学 一种医药用木本α-亚麻酸的提纯方法及其应用
CN110105199A (zh) * 2019-05-23 2019-08-09 河南农业大学 一种静脉注射用木本α-亚麻酸的提纯方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01207257A (ja) * 1988-02-15 1989-08-21 Nippon Oil & Fats Co Ltd α−リノレン酸の分離法

Also Published As

Publication number Publication date
KR970002037B1 (ko) 1997-02-21
JPH08208531A (ja) 1996-08-13
US5672726A (en) 1997-09-30
JP2819455B2 (ja) 1998-10-30

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