KR950030883A - 정제 제조방법과 장치 및 그로부터 제조된 정제 - Google Patents

정제 제조방법과 장치 및 그로부터 제조된 정제 Download PDF

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KR950030883A
KR950030883A KR1019950002451A KR19950002451A KR950030883A KR 950030883 A KR950030883 A KR 950030883A KR 1019950002451 A KR1019950002451 A KR 1019950002451A KR 19950002451 A KR19950002451 A KR 19950002451A KR 950030883 A KR950030883 A KR 950030883A
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씨 푸이즈 리차드
알. 체루쿠리 서브라만
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제럴드 이. 바티스트
푸이즈 테크노로지즈 리미티드
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
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Abstract

본 발명은 압착으로부터 식용 유니트를 제조하기 위한 방법 및 그로 부터 생성된 생성기술이다. 본 발명의 방법은 압착 정제와 같은 식료품 압착 유니트를 형성하기에 충분히 전단형태 매트릭스 덩어리를 압착시키는 것을 포함한다.

Description

정제 제조방법과 장치 및 그로부터 제조된 정제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 공정 및 장치가 선행 기술의 공정 및 장치와 비교된 블록 다이아 그램; 제2(a)도 및 제1(a)도는 본 발명에 따라 제조된 압착 제산 정제의 구조와 선행기술의 압착 제산 정제를 비교한 사진; 제3(a)도는 본 발명에 따라 제조된 예비 압착 입자들로 채워진 압착 자유-형태 응집물의 도해도, 제3(b)도는 선행 기술에 따라 제조된 정제용 예비-압착입자들로 채워진 압착다이의 도해도; 제4(a)도는 본 발명에 따라 제조된 정제의 압착동안의 압착다이의 도해도; 제4(b)도는 선행기술에 따라 정제의 압착동안 압착다이의 도해도; 제5도는 본 발명에 따라 정제된 정제의 1,000배 크기로 찍힌 압착 정제의 사진; 제6(a)도는 1,090배로 찍힌 본 발명의 정제의 사진; 제6(b)도는 1,000배 찍힌 선행 기술 정제의 사진.

Claims (24)

  1. 식료품 압착 유니트를 형성하기에 충분히 전단형태 매트릭스 덩어리를 압착하는 것을 포함하는 고체 식료품 제조방법.
  2. 제1항에 있어서, 전단형태 매트릭스의 상기 덩어리가 공급원료 물질을, 공급원료 물질이 식료품 압착유니트를 형성하도록 압착가능한 변형가능하고 랜덤형 및 랜덤 크기의 입자로 변형되게 하는 플래쉬-유동으로 처리하여 형성되는 방법.
  3. 제2항에 있어서, 상기 플래쉬-유동이 상기 공급원료가 플래쉬-유동을 생성하기에 충분한 열 및 전단을 받고, 스피닝동안 상기 덩어리로 방출하는 스피닝 헤드에서 고속 스피닝에 의해 제공되는 방법.
  4. 제2항에 있어서, 상기 플래쉬-유동이 내부 유동조건을 제공하기에 충분히 용해된 조건의 상기 공급원료를 가열하고, 상기 공급원료를 상기 공급원료 상기 덩어리를 형성하도록 파괴적인 유체 전단힘을 받게하여 제공되는 방법.
  5. 제2항에 있어서, 상기 공급원료가 상기 매트릭스를 생성하도록 플래쉬-유동처리동안 형태학적 변형을 겪는 담체물질을 포함하는 방법.
  6. 제5항에 있어서, 상기 공급원료가 플래쉬-유동 처리동안 혼합되고 상기 매트릭스에 미세구조적으로 안정화된 첨가제를 추가로 포함하는 방법.
  7. 제6항에 있어서, 상기 첨가제가 약제, 염료, 방향, 감미제, 풍미, 충진제, 결합제, 윤활제, 붕해제 및 이들의 혼합물로 구성되는 그룹으로부터 선택된 방법.
  8. 제7항에 있어서, 상기 첨가제는 진해제, 항히스타민제, 오염제거약, 알칼로이드, 미네랄 보충제, 이완제, 비타민, 제산제, 이온 교환수지, 항-콜레스테롤레믹제(anti-cholesterolemics), 항지질제, 항부정맥제, 해열제, 진통제, 식욕억제제, 거담제, 항불안제, 항궤양제, 항염물질, 관상동맥 확장제, 뇌 확장제(cerebraldilators), 항말초성 혈관확장 신경제, 항감염제, 정신-트로픽제(trocipcs), 항매닉제(antimanics), 자극제, 위장관제, 진정제, 항설사제, 항-앤지날제(anti-anginal), 혈관확장신경제, 항민감성제, 혈과수축신경제, 편두통처리제, 항생제 신경안정제, 항정신병제, 항종양제, 응고방지제, 항트롬보제, 최면제, 진토제, 항오심제, 항-컨벌선트제(anti-convulsants), 신경근육제, 고혈당제 및 저혈당제, 갑상선제 및 항갑상선제, 이뇨제, 진경제, 자궁이완제, 미네랄 및 영양 첨가제, 항비만증제, 신진대사제, 조혈제, 항천식제, 기침억제제, 뮤콜리틱, 항요산혈증제 및 그들의 혼합물로 구성되는 약제이다.
  9. 제8항에 있어서, 상기 약제가 제산제인 방법.
  10. 제1항에 있어서, 상기 압착이 처리보조를 위한 요구없이 수행되는 방법.
  11. 덩이리들 각각안에서 서로에 대해서 미세구조적으로 안정화된 성분들의 혼합물을 갖는 전단형태 매트릭스 덩어리로부터 형성된 실질적으로 연속적인 압착 몸체를 포함하는 고체 식료품.
  12. 제11항에 있어서, 상기 성분들이 담체 물질 및 적어도 하나의 첨가제를 포함하는 식료품.
  13. 제12항에 있어서, 상기 적어도 하나의 첨가제가 약제, 염료, 방향, 감미제, 풍미, 충진제, 결합제, 윤활제, 봉해제 및 그들의 혼합물로 구성되는 그룹으로부터 선택된 식료품.
  14. 제13항에 있어서, 상기 첨가제가 진해제, 항히스타민제, 오염제거약, 알칼로이드, 미네랄 보충제, 이완제, 비타민, 제산제, 이온 교환수지, 항-콜레스테롤레믹제(anti-cholesterolemincs), 항지질제, 항부정맥제, 해열제, 진통제, 식욕억제제, 거담제, 항불안제, 항궤양제, 항염물질, 관상동맥 확장제, 뇌 확장제, 항말초성 혈관확장 신경제, 항감염제, 정신-트로픽제(trocipcs), 항매닉제(antimanics), 자극제, 위장관제, 진정제, 항설사제, 항-앤지날제(anti-anginal), 혈과확장신경제, 항민감성제, 혈과수축신경제, 편두통처리제, 항생제 신경안정제, 항정신병제, 항종양제, 응고방지제, 항트롬보제, 최면제, 진토제, 항오심제, 항-컨벌선트제(anti-convulsants), 신경근육제, 고혈당제 및 저혈당제, 갑상선제 및 항갑상선제, 이노제, 진경제, 자궁이완제, 미네랄 및 영양 첨가제, 항비만증제, 신진대사제, 조혈제, 항천식제, 기침억제제, 뮤콜리틱, 항요산혈증제 및 이들의 혼합물로 구성되는 그룹으로부터 선택된 약제인 식료품.
  15. 제11항에 있어서, 상기 실질적으로 연속적인 압착 몸체가 상기 몸체를 형성하기에 충분히 전단형태 매트릭스 덩어리를 압착하여 형성되는 식료품.
  16. 제11항에 있어서, 전단형태 매트릭스의 상기 덩어리가 공급원료 물질을, 공급원료 물질이 상기 몸체로 형성하도록 압착될 수 있는 변형가능하고 랜덤형 및 랜덤크기의 입자들로 변형되게하는, 플래쉬-유동으로 처리하여 형성되는 식료품.
  17. 제16항에 있어서, 상기 플래쉬-유동이 상기 공급원료가 플래쉬-유동을 생성하기에 충분한 열 및 전단을 받고, 스피닝동안 상기 덩어리를 방출하는 스피닝헤드에서 고속 스피닝에 의해 제공되는 식료품.
  18. 제16항에 있어서, 상기 플래쉬-유동이 내부 유동조건을 제공하기에 충분히 상기 공급원료를 비용해된 조건에서 가열하고, 상기 공급원료를 상기 덩어리를 형성하도록 파괴적인 유체 전단력을 받게하여 제공되는 식료품.
  19. 제16항에 있어서, 상기 공급원료가 상기 매트릭스를 식료품 생성하도록 상기 플래쉬-유동 처리동안 형태학적 변형을 겪는 담체물질을 포함하는 식료품.
  20. 제19항에 있어서, 상기 공급원료가 플래쉬-유동 처리동안 혼합되고 상기 매트릭스에 미세구조적으로 안정화된 첨가제를 추가로 포함하는 식료품.
  21. 제11항에 있어서, 상기 몸체가 입자들의 붕해를 향상시키고 상기 입자 각각의 습윤성을 개선시키는 붕해간극을 갖는 식료품.
  22. 전단형태 매트릭스를 형성되기 위한 플래쉬-유동장치, 및 적어도 하나의 다이공동부 및 압착 펀치를 갖는 압착 정제화기를 포함하고, 상기 압착 정제화기가 상기 플래쉬-유동장치로부터 전단형태 매트릭스의 압착 형성을 위한 상기 적어도 하나의 다이 공동부로 전단형태 미트릭스 덩어리를 전달하기 위하여 상기 플래쉬-유동 장치에 연결된 압착 식료품 유니트 제조장치.
  23. 제22항에 있어서, 상기 플래쉬-유동장치가 자유-형태 용융 스피닝 장치인 장치.
  24. 제22항에 있어서, 상기 플래쉬-유동장치가 전단형태 매트릭스를 형성하기 위한 장치.
    ※ 참고사항 : 최초출원 내용에 의하여 공개되는 것임.
KR1019950002451A 1994-02-10 1995-02-10 정제 제조방법과 장치 및 그로부터 제조된 정제 KR950030883A (ko)

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KR102076831B1 (ko) 2019-07-05 2020-02-12 (주)알피바이오 수계코팅용 천연유래 소재 정제 조성물 및 이를 이용한 식물성 수계코팅 정제
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US5654003A (en) 1997-08-05
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EP0667147A3 (en) 1996-04-24
JPH0838138A (ja) 1996-02-13
EP0667147A2 (en) 1995-08-16

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