KR950018365A - 살균 시아노아크릴레이트 접착 조성물 및 그 제조방법 - Google Patents

살균 시아노아크릴레이트 접착 조성물 및 그 제조방법 Download PDF

Info

Publication number
KR950018365A
KR950018365A KR1019940036278A KR19940036278A KR950018365A KR 950018365 A KR950018365 A KR 950018365A KR 1019940036278 A KR1019940036278 A KR 1019940036278A KR 19940036278 A KR19940036278 A KR 19940036278A KR 950018365 A KR950018365 A KR 950018365A
Authority
KR
South Korea
Prior art keywords
composition
irradiation
amount
cyanoacrylate
parts per
Prior art date
Application number
KR1019940036278A
Other languages
English (en)
Other versions
KR0146409B1 (ko
Inventor
프랜시스 맥도넬 패트릭
조제프 램버트 로버트
Original Assignee
데이비드 피. 멜로디
록타이트 (아일랜드) 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 데이비드 피. 멜로디, 록타이트 (아일랜드) 리미티드 filed Critical 데이비드 피. 멜로디
Publication of KR950018365A publication Critical patent/KR950018365A/ko
Application granted granted Critical
Publication of KR0146409B1 publication Critical patent/KR0146409B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J11/00—Features of adhesives not provided for in group C09J9/00, e.g. additives
    • C09J11/02—Non-macromolecular additives
    • C09J11/06—Non-macromolecular additives organic
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J4/00—Adhesives based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond ; adhesives, based on monomers of macromolecular compounds of groups C09J183/00 - C09J183/16

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymerisation Methods In General (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

본 발명에 따르면 의학적 및/또는 수의학적으로 사용하기 위해 기도된 경화성 시아노아크릴레이트 접착조성물이 액체 형태로 감마선 조사에 의해 살균된다. 본 조성물은 a) 시아노아크릴레이트 단량체 및 b) 조사동안 조성물을 안정화하고 경화전 저장동안 살균조성물을 안정화하는데 유효한 양으로의 음이온 안정제와, 선택된 페놀계 산화방지제(그러나 히드러퀴논은 포함되지 않음)인 자유라디칼 안정제의 조합물로 이루어진다.
바람직한 자유라디칼 안정제는 부틸화 히드록시아니솔이다. 조사후 시아노아크릴레이트 단량체는 실질적으로 겔화되지 않는다.

Description

살균 시아노아크릴레이트 접착 조성물 및 그 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (15)

  1. 결합하는데 사용하기 위한 경화성 시아노아크릴레이트 접착조성물에 있어서, 상기 조성물은 감마선 조사에 의해 액체 형태로 살균되었고 a) 시아노아크릴레이트 단량체 및 b) 조사동안 조성물을 안정화하고 경화전 저장동안 살균조성물을 안정화하는데 유효한 양으로의 음이온 안전제와 자유라디칼 안정제의 조합물로 이루어진 조성물의 조사 생성물이며, 상기 자유라디칼 안정제는 다음 식 I 또는 II
    (식에서, R5는 -H, 탄소원자수 1 내지 20의 알킬기, 탄소원자수 2 내지 20의 알켄일기 또는 탄소원자수 6 내지 36의 아릴기이고, 동일 또는 상이할 수 있는 R1, R2, R3, R4는 각각 R5또는 -OR5이다. 단, R1, R2, R4및 R5가 각각 -H일 경우 R3는 -OH가 아니다.),
    (식에서, R2, R3, R4및 R5는 위에 정의한 바와 같고, 동일 또는 상이할 수 있는 R6, R7, R8, R9및 R10은 각각 R5또는 -OR5이다.)의 화합물중에서 선택된 페놀계 산화방지제이고, 조사후 살균 액체조성물내의 시아노아크릴레이트 단량체는 실질적으로 겔화되지 않은 것을 특징으로 하는 시아노아크릴레이트 접착조성물.
  2. 제1항에 있어서, 식 I 또는 II의 화합물에서 R1, R2, R4및 R5중의 적어도 하나(그리고 식 II의 화합물의 경우 R7, R8및 R10중의 적어도 하나)는 -C(CH3)인 것을 특징으로 하는 조성물.
  3. 제1항에 있어서, 식 I 또는 II의 화합물에서 R3(그리고 식 II의 화합물의 경우 R9도)는 -CH3및 -OCH3중에서 선택되는 것을 특징으로 하는 조성물.
  4. 제1항에 있어서, 식 I의 화합물은 부틸화 히드록시아니솔인 것을 특징으로 하는 조성물.
  5. 제4항에 있어서, 부틸화 히드록시아니솔은 조사전에 백만중량당 1000부 이상의 양으로 존재하는 것을 특징으로 하는 조성물.
  6. 제5항에 있어서, 부틸화 히드록시아니솔은 조사전에 백만중량당 1500부 이상의 양으로 존재하는 것을 특징으로 하는 조성물.
  7. 제1항에 있어서, 시아노아크릴레이트 단량체는 n-부틸, 이소-부틸 및 sec-붙틸 시아노아크릴레이트중에서 선택되고, 바람직하게는 n-부틸 시아노아크릴레이트인 것을 특징으로 하는 조성물.
  8. 제1항에 있어서, 시아노아크릴레이트 단량체는 대응하는 알킬 시아노아세테이트와 파라포름알데히드 사이의 크뇌베나겔 반응에 의해 제조하고, 그 다음 공정 오염물을 제거하기 위해 열분해 및 증류하는 것을 특징으로 하는 조성물.
  9. 제1항에 있어서, 음이온 안정제는 이산화황 또는 황산인 것을 특징으로 하는 조성물.
  10. 제9항에 있어서, 이산화황은 조사전에 백만중량당 20 내지 150부 범위내의 양으로 존재하는 것을 특징으로 하는 조성물.
  11. 결합하는데 사용하기 위한 경화성 살균 시아노아크릴레이트 접착조성물의 제조방법에 있어서, (a) 시아노아크릴레이트 단량체 및 (b) 감마선 조사에 의한 살균동안 조성물을 안정화하고 경화전 저장동안 살균 조성물을 안정화하는데 유효한 양으로의 음이온 안정제와, 특허청구의 범위 제1항에 규정된 바의 식 I 또는 II의 화합물중에서 선택된 페놀게산화 방지제인 자유라디칼 안정제의 조합물로 이루어진 액체 조성물을 제조하고 이 조성물을 시아노아크릴레이트 단량체의 실질적인 겔화없이 조성물을 살균하기에 충분한 선량으로 감마선 조사에 액체 형태로 노출하는 것으로 이루어지는 것을 특징으로 하는 제조방법.
  12. 제11항에 있어서, 음이온 안정제는 조사전 조성물내에 조성물 백만중량당 15 내지 500부 범위내의 양으로 존재하는 것을 특징으로 하는 제조방법.
  13. 제12항에 있어서, 음이온 안정제는 백만중량당 40-120부 범위내의 양으로 존재하는 것을 특징으로 하는 제조방법.
  14. 제11항에 있어서, 페놀계 산화방지제는 조사전 조성물내에 조성물 백만중량당 적어도 1500부의 양으로 존재하는 것을 특징으로 하는 제조방법.
  15. 제14항에 있어서, 페놀계 산화방지제는 백만중량당 2000부 이상의 양의 부틸화 히드록시아니솔인 것을 특징으로 하는 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940036278A 1993-12-23 1994-12-23 살균 시아노아크릴레이트 접착 조성물 및 그 제조방법 KR0146409B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE931009 1993-12-23
IE931009 1993-12-23

Publications (2)

Publication Number Publication Date
KR950018365A true KR950018365A (ko) 1995-07-22
KR0146409B1 KR0146409B1 (ko) 1998-08-01

Family

ID=11040232

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940036278A KR0146409B1 (ko) 1993-12-23 1994-12-23 살균 시아노아크릴레이트 접착 조성물 및 그 제조방법

Country Status (15)

Country Link
US (1) US5530037A (ko)
EP (1) EP0659441B1 (ko)
JP (1) JP3245830B2 (ko)
KR (1) KR0146409B1 (ko)
AT (1) ATE214952T1 (ko)
AU (1) AU688418B2 (ko)
BR (1) BR9405219A (ko)
CA (1) CA2138689C (ko)
DE (1) DE69430233T2 (ko)
DK (1) DK0659441T3 (ko)
ES (1) ES2173908T3 (ko)
HK (1) HK1004199A1 (ko)
PT (1) PT659441E (ko)
SI (1) SI0659441T1 (ko)
TW (1) TW359683B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012060623A2 (ko) * 2010-11-02 2012-05-10 (주)인튜이티브메디코프 시아노아크릴레이트계 생체 접착제 조성물

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2306469B (en) * 1995-11-02 1998-05-13 Chemence Ltd Sterilising cyanoacrylate preparations
US5730994A (en) * 1997-01-10 1998-03-24 Medlogic Global Corporation Methods for draping surgical incision sites
US6476069B2 (en) 1997-09-11 2002-11-05 Provasis Therapeutics Inc. Compositions for creating embolic agents and uses thereof
AU1923199A (en) * 1997-12-17 1999-07-05 Hemodynamics, Inc. Sealing media for surgery and wound closure
US20050245966A1 (en) * 1997-12-17 2005-11-03 Hammerslag Julius G Controlled viscosity tissue adhesive
US6143805A (en) * 1998-02-18 2000-11-07 Closure Medical Corporation Electron beam sterilization of liquid adhesive compositions
US6512023B1 (en) * 1998-06-18 2003-01-28 Closure Medical Corporation Stabilized monomer adhesive compositions
US6372313B1 (en) * 1998-09-01 2002-04-16 Closure Medical Corporation Package assembly with applicator and container for adhesive materials
CA2342342A1 (en) 1998-09-01 2000-03-09 Keith R. D'alessio Package assembly with applicator and container for adhesive materials
JP4249395B2 (ja) * 1998-09-18 2009-04-02 メドロジック グローバル リミテッド シアノアクリル酸エステル組成物を無菌化する方法
GB9820457D0 (en) 1998-09-18 1998-11-11 Medlogic Global Corp Methods for sterilizing cyanoacrylate compositions
US7083634B2 (en) * 1998-11-12 2006-08-01 Poly Med Inc Stabilized polyester/cyanoacrylate tissue adhesive formulation
AU5305100A (en) 1999-05-29 2000-12-18 Tyco Healthcare Group Lp Bioabsorbable blends and surgical articles therefrom
US6352704B1 (en) * 1999-06-30 2002-03-05 Closure Medical Corporation Flavored cyanoacrylate compositions
US6310166B1 (en) 1999-08-12 2001-10-30 Closure Medical Corporation Sterilized cyanoacrylate solutions containing thickeners
AU7124400A (en) * 1999-09-09 2001-04-10 Loctite Corporation Radiation-curable, cyanoacrylate-containing compositions
US6579469B1 (en) * 1999-10-29 2003-06-17 Closure Medical Corporation Cyanoacrylate solutions containing preservatives
DE60139112D1 (de) * 2000-03-06 2009-08-13 Boston Scient Ltd Unter ultralschall sichtbare embolisierende substanzen
US6605667B1 (en) * 2000-09-08 2003-08-12 Closure Medical Corporation Antioxidant enriched adhesive compositions and storage containers therefor
US6734221B1 (en) 2000-09-08 2004-05-11 Loctite (R&D) Limited Radiation-curable, cyanoacrylate-containing compositions
US6579916B1 (en) 2000-11-21 2003-06-17 Medlogic Global Corporation Methods for sterilizing cyanoacrylate compositions
AU2002243215A1 (en) * 2000-11-21 2002-07-24 Medlogic Global Corporation Method for sterilizing cyanoacrylate compositions
US6602496B2 (en) 2001-07-05 2003-08-05 Closure Medical Corporation Adhesive treatment for tinea corporis
US6767552B2 (en) 2001-07-05 2004-07-27 Closure Medical Corporation Adhesive treatment for oral fungal infection
US6746667B2 (en) 2001-07-05 2004-06-08 Closure Medical Corporation Adhesive treatment for tinea pedis
US6942875B2 (en) * 2001-07-05 2005-09-13 Closure Medical Corporation Adhesive treatment for skin yeast infections
US6585967B2 (en) 2001-07-05 2003-07-01 Closure Medical Corporation Adhesive treatment for tinea cruris
US7709556B2 (en) * 2002-10-09 2010-05-04 Poly-Med, Inc. Radiation and radiochemically sterilized absorbable devices with dose-controlled functional strength retention
WO2005000985A2 (en) * 2003-06-03 2005-01-06 Medlogic Global Limited Antimicrobial phenol containing cyanoacrylate adhesive compositions
WO2005006991A2 (en) * 2003-07-18 2005-01-27 Chiroxia Limited Device and method for fallopian tube occlusion
EP1548077A1 (en) * 2003-12-26 2005-06-29 Biotechnology Institute BTI I+D cyanoacrylic-based adhesive composition for sealing biological tissues
US20120245703A1 (en) * 2004-01-02 2012-09-27 Meredith Thomas L Composite bone material implant and method
IE20040065A1 (en) 2004-02-02 2005-08-10 Loctite R & D Ltd Rapidly curing formulations including a conductive component
GB0402838D0 (en) * 2004-02-10 2004-03-17 Univ Belfast Method
US20050196376A1 (en) * 2004-03-03 2005-09-08 G. L. Loomis & Associates, Inc. Preparation of polymerizable compositions
US20050197421A1 (en) * 2004-03-03 2005-09-08 Loomis Gary L. Process for preparation of cyanoacrylate compositions
US8110144B2 (en) * 2004-09-17 2012-02-07 Chemence Medical, Inc. Process for sterilization of and cyanoacrylate adhesives compositions and devices
US20060093572A1 (en) * 2004-11-03 2006-05-04 Bordoloi Binoy K Cyanoacrylate monomer formulation containing diiodomethyl-p-tolylsulfone and 2,4,4'-trichloro-2' -hydroxydiphenyl ether
EP1843800B1 (en) 2005-01-14 2009-05-13 Henkel AG & Co. KGaA Radiopaque cyanoacrylate compositions
US8061917B2 (en) * 2005-06-10 2011-11-22 Medlogic Global Limited Liquid applicator and method of use
CA2615699A1 (en) * 2005-07-01 2007-01-11 Carolyn M. Dry Multiple function, self-repairing composites with special adhesives
WO2007008971A1 (en) * 2005-07-11 2007-01-18 Henkel Corporation Toughened cyanoacrylate compositions
CN1318099C (zh) * 2005-07-29 2007-05-30 商菁华 一种粘合剂的用途
US20070078207A1 (en) * 2005-09-30 2007-04-05 Jonn Jerry Y Stabilizer cyanoacrylate formulations
US20070248486A1 (en) * 2006-04-24 2007-10-25 Clast Trading Ltd Process for Sterilization of Cyanoacrylate Adhesive Compositions and Devices
DE102006027305B4 (de) * 2006-06-06 2016-12-22 Aesculap Ag Verfahren zur Sterilisation einer gasdurchlässigen und keimdichten Verpackung
US7772306B2 (en) * 2006-07-18 2010-08-10 Glustitch, Inc. Cyanoacrylate compositions having increased stability under irradiation
EP2137275A1 (de) * 2007-04-18 2009-12-30 Henkel AG & Co. KGaA Schnell aushärtende cyanacrylate als klebstoffe
US20080311323A1 (en) * 2007-06-12 2008-12-18 Chemence, Inc. Cyanoacrylate Adhesive Compositions and Devices and Process for Sterilization Thereof
US8729121B2 (en) 2007-06-25 2014-05-20 Adhezion Biomedical, Llc Curing accelerator and method of making
EP2742875B1 (en) * 2007-11-14 2016-02-24 Adhezion Biomedical, LLC Cyanoacrylate tissue adhesives
US8815975B2 (en) * 2008-04-18 2014-08-26 Poly-Med, Inc. Cyanoacrylate tissue adhesive formulations with multipurpose rheology modifiers
US8198344B2 (en) * 2008-06-20 2012-06-12 Adhezion Biomedical, Llc Method of preparing adhesive compositions for medical use: single additive as both the thickening agent and the accelerator
US8293838B2 (en) * 2008-06-20 2012-10-23 Adhezion Biomedical, Llc Stable and sterile tissue adhesive composition with a controlled high viscosity
US20110117047A1 (en) 2008-06-23 2011-05-19 Adhezion Biomedical, Llc Cyanoacrylate tissue adhesives with desirable permeability and tensile strength
US8652510B2 (en) 2008-10-31 2014-02-18 Adhezion Biomedical, Llc Sterilized liquid compositions of cyanoacrylate monomer mixtures
US8609128B2 (en) 2008-10-31 2013-12-17 Adhezion Biomedical, Llc Cyanoacrylate-based liquid microbial sealant drape
US9254133B2 (en) 2008-10-31 2016-02-09 Adhezion Biomedical, Llc Sterilized liquid compositions of cyanoacrylate monomer mixtures
EP2424933B1 (en) 2009-05-01 2013-08-21 Henkel Ireland Limited Cyanoacrylate compositions
US9309019B2 (en) 2010-05-21 2016-04-12 Adhezion Biomedical, Llc Low dose gamma sterilization of liquid adhesives
US8927603B2 (en) 2010-06-07 2015-01-06 Adhezion Biomedical, Llc X-ray sterilization of liquid adhesive compositions
JP5629009B2 (ja) 2010-09-15 2014-11-19 ヘンケル アイルランド リミテッド 二成分系シアノアクリレート／カチオン硬化性接着剤システム
CN101967354B (zh) * 2010-09-15 2013-07-31 北京天山新材料技术股份有限公司 低白化α-氰基丙烯酸酯胶粘剂
JP5878631B2 (ja) 2011-07-15 2016-03-08 ヘンケル アイピー アンド ホールディング ゲゼルシャフト ミット ベシュレンクテル ハフツング シアノアクリレート組成物
US9657120B1 (en) 2011-09-06 2017-05-23 Henkel IP & Holding GmbH Cyanoacrylate compositions
WO2013111036A1 (en) 2012-01-23 2013-08-01 Henkel Ireland Limited Two-part, cyanoacrylate/free radically curable adhesive systems
US9550883B2 (en) 2012-01-25 2017-01-24 Henkel IP & Holding GmbH Cyanoacrylate compositions
US8685513B1 (en) 2012-02-29 2014-04-01 Carolyn M. Dry Inflatable articles comprising a self-repairing laminate
US9694629B1 (en) 2012-02-29 2017-07-04 Carolyn Dry Self-repairing inflatable articles incorporating an integrated self-repair system
JP5649191B2 (ja) * 2012-03-26 2015-01-07 田岡化学工業株式会社 ２−シアノアクリレート系接着剤組成物
DE102012216425A1 (de) 2012-09-14 2014-03-20 Aesculap Ag Zusammensetzung, insbesondere zur Adhäsionsprophylaxe und/oder zum Wundverschluss
US9783714B2 (en) * 2013-03-15 2017-10-10 Henkel IP & Holding GmbH Cyanoacrylate compositions
US8981027B2 (en) 2013-03-15 2015-03-17 Henkel IP & Holding GmbH Two-part, cyanoacrylate/cationically curable adhesive systems
JP6461924B2 (ja) 2013-05-21 2019-01-30 ヘンケル アイピー アンド ホールディング ゲゼルシャフト ミット ベシュレンクテル ハフツング シアノアクリレート組成物
US9421297B2 (en) 2014-04-02 2016-08-23 Adhezion Biomedical, Llc Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides
CN105080781A (zh) * 2014-05-22 2015-11-25 劲捷生物科技股份有限公司 加速黏合剂固化反应的涂布器及方法
US9683816B2 (en) 2014-09-08 2017-06-20 Carolyn Dry Self-repairing armor
WO2016099512A1 (en) 2014-12-18 2016-06-23 Compagnie Generale Des Etablissements Michelin Microstructured composites for improved tire characteristics
WO2016099510A1 (en) 2014-12-18 2016-06-23 Compagnie Generale Des Etablissements Michelin Microstructured composites for improved tire characteristics
GB2544101B (en) 2015-11-06 2020-07-15 Henkel IP & Holding GmbH Rubber toughened cyanoacrylate compositions and uses thereof
GB2544272B (en) 2015-11-06 2020-02-19 Henkel IP & Holding GmbH Cyanoacrylate compositions
JPWO2017175540A1 (ja) * 2016-04-06 2019-02-14 株式会社カネカ 耐放射線性樹脂添加剤、耐放射線性医療用ポリアミド樹脂組成物及び耐放射線性医療用成形体
GB2550846B (en) 2016-05-23 2021-01-13 Henkel IP & Holding GmbH Two-part Cyanoacrylate curable adhesive system
CN110267687A (zh) * 2017-02-09 2019-09-20 费玛塞斯公司 包括可生物降解的氰基丙烯酸酯的组合物和方法
GB2562107B (en) 2017-05-05 2021-08-11 Henkel IP & Holding GmbH Cyanoacrylate compositions
GB2567868B (en) 2017-10-27 2020-05-06 Henkel IP & Holding GmbH Toughened low odour cyanoacrylate compositions
GB201802243D0 (en) 2018-02-12 2018-03-28 Henkel IP & Holding GmbH Cyanoacrylate compositions
GB2576792B (en) 2018-08-13 2022-09-14 Henkel Ag & Co Kgaa A two-part cyanoacrylate curable adhesive system
GB2576791B (en) 2018-08-13 2022-09-14 Henkel Ag & Co Kgaa A two-part cyanoacrylate curable adhesive system
GB2576704B (en) 2018-08-16 2022-01-12 Henkel IP & Holding GmbH Cyanoacrylate compositions
JP7461932B2 (ja) 2018-08-23 2024-04-04 シンテフ ティーティーオー エイエス ナノ粒子
JPWO2020085334A1 (ja) * 2018-10-23 2021-09-24 東亞合成株式会社 光硬化性接着剤組成物
GB2582537B (en) 2019-03-04 2022-02-23 Henkel IP & Holding GmbH Two-part, cyanoacrylate/cationically curable adhesive systems
KR102281485B1 (ko) * 2019-06-19 2021-07-28 주식회사 오쎄인 시안화아크릴레이트의 점도 변화에 따른 물성변화를 통한 골대체용 복합재료의 제조방법 및 그것의 조성물
KR20220104697A (ko) 2019-11-18 2022-07-26 헨켈 아게 운트 코. 카게아아 2 성분 (2k) 경화성 조성물
GB2590495A (en) 2019-12-20 2021-06-30 Henkel IP & Holding GmbH A container for, and a pack including, cyanoacrylate composition(s)
GB2596355B (en) 2020-06-26 2022-09-28 Henkel Ag & Co Kgaa Cyanoacrylate compositions
JP2024514387A (ja) 2021-03-05 2024-04-02 エイチ．ビー．フラー カンパニー 害のない安定剤を有するシアノアクリレート組成物
CN113679876B (zh) * 2021-08-13 2022-08-12 上海恩盛医疗科技有限公司 一种医用软组织粘合剂及其制备方法
GB2613555A (en) 2021-12-03 2023-06-14 Henkel IP & Holding GmbH Method of underwater bonding
EP4285946A1 (en) * 2022-06-03 2023-12-06 B. Braun Surgical, S. A. Surgical thread, surgical suture and surgical kit
US20230404067A1 (en) * 2022-06-14 2023-12-21 BioChoric, Inc. Method and apparatus for reducing probability of ice nucleation during preservation of biological matter in isochoric systems
WO2024003053A1 (en) 2022-06-28 2024-01-04 Henkel Ag & Co. Kgaa Method of underwater bonding

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3527224A (en) * 1967-09-05 1970-09-08 American Cyanamid Co Method of surgically bonding tissue together
NL163797C (nl) * 1969-10-10 Loctite Ireland Ltd Werkwijze voor het bereiden van hechtmiddelsamen- stellingen op basis van esters van alfa-cyaanacrylzuur, die een weekmaker bevatten.
GB1281457A (en) * 1969-11-17 1972-07-12 Oesterr Studien Atomenergie Sterilisation of tissue binding adhesives
JPS4916102A (ko) * 1972-06-08 1974-02-13
US4100141A (en) * 1976-07-02 1978-07-11 Loctite (Ireland) Limited Stabilized adhesive and curing compositions
BR8008824A (pt) * 1979-09-12 1981-06-23 Population Res Inc Esterilizacao feminina
US4820755A (en) * 1987-08-18 1989-04-11 American Cyanamid Company Radiation sterilizable composition and articles made therefrom
US5403591A (en) * 1993-06-25 1995-04-04 Medlogic Global Corporation Methods for inhibiting skin ulceration by use of cyanoacrylate adhesives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012060623A2 (ko) * 2010-11-02 2012-05-10 (주)인튜이티브메디코프 시아노아크릴레이트계 생체 접착제 조성물
WO2012060623A3 (ko) * 2010-11-02 2012-07-05 (주)인튜이티브메디코프 시아노아크릴레이트계 생체 접착제 조성물

Also Published As

Publication number Publication date
DE69430233D1 (de) 2002-05-02
ES2173908T3 (es) 2002-11-01
BR9405219A (pt) 1995-08-01
HK1004199A1 (en) 1998-11-20
AU688418B2 (en) 1998-03-12
JP3245830B2 (ja) 2002-01-15
DE69430233T2 (de) 2002-11-14
CA2138689A1 (en) 1995-06-24
EP0659441B1 (en) 2002-03-27
ATE214952T1 (de) 2002-04-15
AU8166494A (en) 1995-06-29
JPH07252455A (ja) 1995-10-03
KR0146409B1 (ko) 1998-08-01
TW359683B (en) 1999-06-01
DK0659441T3 (da) 2002-07-29
SI0659441T1 (en) 2002-08-31
PT659441E (pt) 2002-08-30
CA2138689C (en) 2000-02-22
EP0659441A1 (en) 1995-06-28
US5530037A (en) 1996-06-25

Similar Documents

Publication Publication Date Title
KR950018365A (ko) 살균 시아노아크릴레이트 접착 조성물 및 그 제조방법
US7772306B2 (en) Cyanoacrylate compositions having increased stability under irradiation
KR920008524B1 (ko) 조사에 안정한 고투명도의 중합 조성물 및 이것으로 만든 제품
US20050196376A1 (en) Preparation of polymerizable compositions
ES2149909T3 (es) Procedimiento para la obtencion de cementos oseos que contienen principios activos.
DE4009715C2 (ko)
DE69123023D1 (de) Gleitfähige, gegen Strahlung beständige Polymermasse und Gegenstände daraus
WO2008005634A1 (en) Absorbable cyanoacrylate compositions
US3740850A (en) Tertiary aromatic amine accelerators in dental compositions
DE2439738C2 (de) Anaerobe Klebemasse
EP0457048A1 (en) Radiation-resistant propylene polymer composition and radiation sterilized articles therefrom
ES389545A2 (es) Un procedimiento de preparar nuevos tiofosfitos y tiofosfa-tos organicos.
DE2006630A1 (de) Polyester-Polyacrylate und daraus hergestellte Massen
EP0542439B1 (en) Polymerisable compositions
DE1807297C3 (de) Benzoinsilyläthec, deren Herstellung und Verwendung
DE2330667A1 (de) Produkte aus einem imidazol und schwefeldioxid, diese enthaltende massen und verfahren zur herstellung der produkte und massen
KR870007986A (ko) 오르가노폴리실록산 경화물의 제조방법
DE2435867A1 (de) Durch strahlung polymerisierbare zusammensetzung
SE191625C1 (ko)
DE1263298B (de) Verwendung von bestimmten Aminen zum Verbessern der Lagerstabilitaet aminhaltiger Polyester-Formmassen
IL33800A (en) Highly stable polymerizable anaerobic compositions and process for preparing them

Legal Events

Date Code Title Description
A201 Request for examination
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20120423

Year of fee payment: 15

FPAY Annual fee payment

Payment date: 20130419

Year of fee payment: 16

LAPS Lapse due to unpaid annual fee