KR930700138A - 안구내 수술용 약제 - Google Patents

안구내 수술용 약제

Info

Publication number
KR930700138A
KR930700138A KR1019920703141A KR920703141A KR930700138A KR 930700138 A KR930700138 A KR 930700138A KR 1019920703141 A KR1019920703141 A KR 1019920703141A KR 920703141 A KR920703141 A KR 920703141A KR 930700138 A KR930700138 A KR 930700138A
Authority
KR
South Korea
Prior art keywords
intraocular
intraocular surgical
biocompatible polymer
drug
thrombolytic
Prior art date
Application number
KR1019920703141A
Other languages
English (en)
Inventor
히로유끼 시미즈
다까히로 오가와
Original Assignee
요시다 쇼오지
센쥬 세이야꾸 가부시기가이샤
후꾸하라 요시하루
가부시기가이샤 시세이도오
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 요시다 쇼오지, 센쥬 세이야꾸 가부시기가이샤, 후꾸하라 요시하루, 가부시기가이샤 시세이도오 filed Critical 요시다 쇼오지
Publication of KR930700138A publication Critical patent/KR930700138A/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)

Abstract

내용 없음.

Description

안구내 수술용 약제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 실시예 1에 있어서의 집토끼의 안압의 변화를 가로축에 시간(hr), 세로축에 안압(mmHg)을 써서 나타낸다, ● ‥‥‥ ● 는 우로키나아제와 히알루론산나트륨을 함유하는 생리식염액을 주입한 눈의 압압을 나타낸다, ■ ‥‥‥ ■ 는 히알루론산만을 함유하는 생리식염액을 주입한 대조안의 안압을 나타낸다.

Claims (4)

  1. 혈전용해성을 지닌 약물을 함유하여서 된 것을 특징으로 하는 안구내수술용제.
  2. 제1항에 있어서 혈전용해성을 지닌 약물이 우로키나아제임을 특징으로 하는 안구내 수술용제.
  3. 제1항 및 제2항에 있어서, 혈전용해성을 지닌 약품과 함께 점탄성을 지닌 생체 적합성이 있는 고분자 화합물을 함유한 것을 특징으로 하는 안구내 수술용제.
  4. 제3항에 있어서, 점탄성을 지닌 생체적합성이 있는 고분자 화합물이 히알루론산 또는 그 염, 콘도이로이틴 황산 또는 그염 및 메틸셀룰로오스로 된 무리에서 선택되는 적어도 1종임을 특징으로 하는 안구내 수술용제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019920703141A 1991-04-22 1992-04-20 안구내 수술용 약제 KR930700138A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3185948A JPH0640943A (ja) 1991-04-22 1991-04-22 眼内手術用剤
JP91-185948 1991-04-22
PCT/JP1992/000509 WO1992018163A1 (fr) 1991-04-22 1992-04-20 Medicament utilise en chirurgie intra-oculaire

Publications (1)

Publication Number Publication Date
KR930700138A true KR930700138A (ko) 1993-03-13

Family

ID=16179682

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920703141A KR930700138A (ko) 1991-04-22 1992-04-20 안구내 수술용 약제

Country Status (9)

Country Link
EP (1) EP0540747B1 (ko)
JP (1) JPH0640943A (ko)
KR (1) KR930700138A (ko)
AT (1) ATE170756T1 (ko)
CA (1) CA2085732A1 (ko)
DE (1) DE69226926T2 (ko)
ES (1) ES2120443T3 (ko)
TW (1) TW203555B (ko)
WO (1) WO1992018163A1 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19606551C2 (de) * 1996-02-22 2000-06-08 Basotherm Gmbh rt-PA zur Prävention des Nachstars nach Kataraktoperation
JP2001213798A (ja) * 2000-01-27 2001-08-07 Mitsubishi-Tokyo Pharmaceuticals Inc 眼科手術補助剤
US20230172969A1 (en) * 2020-04-30 2023-06-08 Rohto Pharmaceutical Co., Ltd. Ophthalmic Composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5455782A (en) * 1977-10-06 1979-05-04 Kowa Co Stable urokinase solution and production thereof
JPS5467089A (en) * 1977-11-07 1979-05-30 Dainippon Pharmaceut Co Ltd Urokinase composition
JPH02167233A (ja) * 1988-11-10 1990-06-27 Kiyoshi Kita 眼内手術補助剤
JPH0236128A (ja) * 1988-07-25 1990-02-06 Kiyoshi Kita 眼内注射剤
JPH02164828A (ja) * 1988-12-19 1990-06-25 Taiho Yakuhin Kogyo Kk 水晶体摘出術後の合併症の治療及び防止剤
JPH03291240A (ja) * 1990-04-09 1991-12-20 Santen Pharmaceut Co Ltd 残留水晶体物質除去補助剤

Also Published As

Publication number Publication date
ATE170756T1 (de) 1998-09-15
CA2085732A1 (en) 1992-10-23
DE69226926D1 (de) 1998-10-15
EP0540747B1 (en) 1998-09-09
EP0540747A4 (en) 1993-08-04
WO1992018163A1 (fr) 1992-10-29
TW203555B (ko) 1993-04-11
JPH0640943A (ja) 1994-02-15
DE69226926T2 (de) 1999-04-22
ES2120443T3 (es) 1998-11-01
EP0540747A1 (en) 1993-05-12

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