EA199700286A1 - Соединение для офтальмологической хирургии и способ ее осуществления - Google Patents

Соединение для офтальмологической хирургии и способ ее осуществления

Info

Publication number
EA199700286A1
EA199700286A1 EA199700286A EA199700286A EA199700286A1 EA 199700286 A1 EA199700286 A1 EA 199700286A1 EA 199700286 A EA199700286 A EA 199700286A EA 199700286 A EA199700286 A EA 199700286A EA 199700286 A1 EA199700286 A1 EA 199700286A1
Authority
EA
Eurasian Patent Office
Prior art keywords
ophthalmic surgery
implementation
connection
miotic
mydriatic agent
Prior art date
Application number
EA199700286A
Other languages
English (en)
Other versions
EA000790B1 (ru
Inventor
Мэйлс А. Гэлин
Джозеф К. Сэламон
Стэнли К. Израэл
Original Assignee
Мэйлс А. Гэлин
Джозеф К. Сэламон
Стэнли К. Израэл
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мэйлс А. Гэлин, Джозеф К. Сэламон, Стэнли К. Израэл filed Critical Мэйлс А. Гэлин
Publication of EA199700286A1 publication Critical patent/EA199700286A1/ru
Publication of EA000790B1 publication Critical patent/EA000790B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/08—Mydriatics or cycloplegics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение относится к соединениям, содержащим вязкоупругий полимер и миотический или мидриатический агент, которые поддерживают структурную целостность передней камеры глаза во время офтальмологической хирургии. Изобретение описывает также соединения, в которых постоянное выделение миотического или мидриатического агента обусловлено микрокапсулами или мицеллами сополимера.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199700286A 1995-04-18 1996-04-18 Соединение для офтальмологической хирургии и способ ее осуществления EA000790B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/423,703 US5612027A (en) 1995-04-18 1995-04-18 Controlled release of miotic and mydriatic drugs in the anterior chamber
PCT/US1996/005395 WO1996032951A1 (en) 1995-04-18 1996-04-18 Controlled release of miotic and mydriatic drugs in the anterior chamber

Publications (2)

Publication Number Publication Date
EA199700286A1 true EA199700286A1 (ru) 1998-04-30
EA000790B1 EA000790B1 (ru) 2000-04-24

Family

ID=23679887

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199700286A EA000790B1 (ru) 1995-04-18 1996-04-18 Соединение для офтальмологической хирургии и способ ее осуществления

Country Status (26)

Country Link
US (4) US5612027A (ru)
EP (1) EP0822822A4 (ru)
JP (1) JP3314085B2 (ru)
KR (1) KR100307685B1 (ru)
CN (1) CN1181703A (ru)
AP (1) AP850A (ru)
AU (1) AU707013B2 (ru)
BG (1) BG62598B1 (ru)
BR (1) BR9608441A (ru)
CA (1) CA2216417C (ru)
CZ (1) CZ326497A3 (ru)
DE (1) DE822822T1 (ru)
EA (1) EA000790B1 (ru)
EE (1) EE9700286A (ru)
ES (1) ES2116950T1 (ru)
GE (1) GEP20002231B (ru)
HU (1) HUP9802665A3 (ru)
IS (1) IS4572A (ru)
MX (1) MX9708043A (ru)
NO (1) NO974808L (ru)
NZ (1) NZ306875A (ru)
OA (1) OA10744A (ru)
PL (1) PL322820A1 (ru)
SK (1) SK140297A3 (ru)
TR (1) TR199701192T1 (ru)
WO (1) WO1996032951A1 (ru)

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US5612027A (en) * 1995-04-18 1997-03-18 Galin; Miles A. Controlled release of miotic and mydriatic drugs in the anterior chamber
CA2250219C (en) 1996-03-28 2008-10-07 Hayat Onyuksel Materials and methods for making improved liposome compositions
US6217886B1 (en) 1997-07-14 2001-04-17 The Board Of Trustees Of The University Of Illinois Materials and methods for making improved micelle compositions
US6391336B1 (en) * 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
HU226104B1 (en) 1998-04-29 2008-04-28 Novartis Ag Methods and compositions for stabilizing acetylcholine compositions
DK172900B1 (da) 1998-12-18 1999-09-27 Per Julius Nielsen Præparat samt kit til brug ved intraoculære operationer
EP1165097B1 (en) 1999-02-01 2007-05-02 Dermal Research Laboratories, Inc. A pharmaceutical composition of complex carbohydrates and their use
US6730065B1 (en) * 2000-09-15 2004-05-04 Ocularis Pharma, Inc. Night vision composition
US6730691B1 (en) 2000-02-10 2004-05-04 Miles A. Galin Uses of alpha adrenergic blocking agents
US20030086899A1 (en) * 2000-03-14 2003-05-08 Jafari Masoud R. Chondroitin sulfate containing viscoelastics for use in treating joints
US7879824B2 (en) * 2001-07-31 2011-02-01 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
US20030060447A1 (en) * 2002-04-24 2003-03-27 Mutlu Karakelle Non-aspirating transitional viscoelastics for use in surgery
WO2002040056A2 (en) 2000-11-06 2002-05-23 Alcon, Inc Carrageenan viscoelastics for ocular surgery
WO2002060486A2 (en) * 2001-01-29 2002-08-08 Fresco Bernard B Controlled release microsphere system for administration of drug to the eye
AU2002360939A1 (en) * 2001-11-21 2003-06-10 Novartis Ag Composition for stabilizing hyaluronic acid
CN101327325A (zh) * 2002-07-30 2008-12-24 奥默罗斯公司 眼科冲洗液及方法
JP2004143155A (ja) * 2002-10-01 2004-05-20 Taisho Pharmaceut Co Ltd 眼科用剤
US20040167480A1 (en) * 2003-02-21 2004-08-26 Advanced Medical Optics, Inc. Administration of multiple viscoelastic solutions with a multi-compartment syringe
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US20100247606A1 (en) * 2009-03-25 2010-09-30 Allergan, Inc. Intraocular sustained release drug delivery systems and methods for treating ocular conditions
EP2413894B1 (en) * 2009-04-02 2017-01-04 Allergan, Inc. Hair-like shaped hydrogels for soft tissue augmentation
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AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Surgical (Ireland) Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI705812B (zh) 2014-12-01 2020-10-01 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
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Also Published As

Publication number Publication date
GEP20002231B (en) 2000-09-25
PL322820A1 (en) 1998-02-16
MX9708043A (es) 1998-03-31
US5965152A (en) 1999-10-12
US5759532A (en) 1998-06-02
AP9701099A0 (en) 1997-10-31
NO974808L (no) 1997-12-15
CA2216417A1 (en) 1996-10-24
CZ326497A3 (cs) 1998-09-16
AU5555796A (en) 1996-11-07
EE9700286A (et) 1998-06-15
CN1181703A (zh) 1998-05-13
ES2116950T1 (es) 1998-08-01
BR9608441A (pt) 1999-02-17
EA000790B1 (ru) 2000-04-24
IS4572A (is) 1997-09-30
DE822822T1 (de) 1998-09-03
NZ306875A (en) 1999-06-29
CA2216417C (en) 2003-03-18
EP0822822A4 (en) 2006-01-11
NO974808D0 (no) 1997-10-17
US5612027A (en) 1997-03-18
EP0822822A1 (en) 1998-02-11
KR19990007837A (ko) 1999-01-25
WO1996032951A1 (en) 1996-10-24
BG101960A (en) 1998-04-30
JP3314085B2 (ja) 2002-08-12
AP850A (en) 2000-06-14
AU707013B2 (en) 1999-07-01
KR100307685B1 (ko) 2001-12-12
BG62598B1 (bg) 2000-03-31
OA10744A (en) 2002-12-11
US5766580A (en) 1998-06-16
TR199701192T1 (xx) 1998-02-21
HUP9802665A2 (en) 1999-06-28
HUP9802665A3 (en) 2000-06-28
JPH10510293A (ja) 1998-10-06
SK140297A3 (en) 1999-01-11

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU