KR930007580B1 - 유두종 비루스 게놈으로부터 유도된 결정 dna 서열, 그의 시험관내 진단 목적용 용도 및 항원 조성물의 제조 방법 - Google Patents

유두종 비루스 게놈으로부터 유도된 결정 dna 서열, 그의 시험관내 진단 목적용 용도 및 항원 조성물의 제조 방법 Download PDF

Info

Publication number
KR930007580B1
KR930007580B1 KR1019870701075A KR870701075A KR930007580B1 KR 930007580 B1 KR930007580 B1 KR 930007580B1 KR 1019870701075 A KR1019870701075 A KR 1019870701075A KR 870701075 A KR870701075 A KR 870701075A KR 930007580 B1 KR930007580 B1 KR 930007580B1
Authority
KR
South Korea
Prior art keywords
dna
hpv
recombinant
sequence
papilloma virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1019870701075A
Other languages
English (en)
Korean (ko)
Inventor
스튜어트 콜
롤프 이. 스트레크
Original Assignee
엥스띠뛰 빠스뙤르
쟝 까스떼
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 엥스띠뛰 빠스뙤르, 쟝 까스떼 filed Critical 엥스띠뛰 빠스뙤르
Application granted granted Critical
Publication of KR930007580B1 publication Critical patent/KR930007580B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1019870701075A 1986-03-21 1987-03-20 유두종 비루스 게놈으로부터 유도된 결정 dna 서열, 그의 시험관내 진단 목적용 용도 및 항원 조성물의 제조 방법 Expired - Lifetime KR930007580B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP86400609.3 1986-03-21
EP86400609 1986-03-21
PCT/EP1987/000158 WO1987005630A1 (en) 1986-03-21 1987-03-20 Determined dna sequences derived from a papillomavirus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions

Publications (1)

Publication Number Publication Date
KR930007580B1 true KR930007580B1 (ko) 1993-08-13

Family

ID=8196291

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870701075A Expired - Lifetime KR930007580B1 (ko) 1986-03-21 1987-03-20 유두종 비루스 게놈으로부터 유도된 결정 dna 서열, 그의 시험관내 진단 목적용 용도 및 항원 조성물의 제조 방법

Country Status (13)

Country Link
US (7) US5554538A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0243221B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JP2633275B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR930007580B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE76429T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU615159B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3779175D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK175314B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2039254T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI100057B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3005272T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO303287B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1987005630A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876922A (en) 1985-07-31 1999-03-02 Institute Pasteur Papillomavirus probe and a process for in vitro diagnosis of papillomavirus infections
WO1987005630A1 (en) * 1986-03-21 1987-09-24 Institut Pasteur Determined dna sequences derived from a papillomavirus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus
FR2629458B2 (fr) * 1987-07-31 1991-08-09 Ire Celltarg Sa Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain
EP0408658A4 (en) * 1988-04-04 1991-10-02 Oncor, Inc. Human papilloma virus typing method and nucleic acid probes used therein
FR2631341B1 (fr) * 1988-05-13 1991-04-26 Pasteur Institut Sondes a papillomavirus hpv49, hpv50, hpv54, hpv55 et produits genetiquement et immunologiquement lies a ce papillomavirus hpv49, hpv50, hpv54, hpv55 et procede de diagnostic in vitro d'infections a papillomavirus et d'immunisation in vivo contre ces papillomavirus
FR2632956B2 (fr) * 1988-05-13 1991-07-12 Pasteur Institut Sondes a papillomavirus hpv49, hpv50, hpv54, hpv55; produits genetiquement et immunologiquement lies a ce papillomavirus hpv49, hpv50, hpv54, hpv55; procede de diagnostic in vitro d'infections a papillomavirus et d'immunisation in vivo contre ces papillomavirus
CA1339729C (en) * 1988-10-26 1998-03-17 Wayne D. Lancaster Human papillomavirus type 52 dna sequences and methods for employing thesame
SE8803870D0 (sv) * 1988-10-28 1988-10-28 Medscand Ab Method for detection of human papillomavirus (hpv) for diagnostic purposes
DE3838269A1 (de) * 1988-11-11 1990-05-17 Behringwerke Ag Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen
EP0662518B1 (en) * 1989-12-01 2001-11-07 VYSIS, Inc. Nucleic acid probes for detection of HPV transcripts
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
FR2656627B1 (fr) * 1989-12-28 1992-04-17 Pasteur Institut Sonde a papillomavirus (hvpv63), notamment pour le diagnostic in vitro d'infections a papillomavirus, pouvant s'accompagner de neoplasies genitales, et produits genetiquement et immunologiquement lies a ce papillomavirus.
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
CA2052413C (en) * 1990-09-28 2004-07-13 Jeffrey L. Joseph Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods
US6013258A (en) * 1997-10-09 2000-01-11 Zycos Inc. Immunogenic peptides from the HPV E7 protein
US6183746B1 (en) 1997-10-09 2001-02-06 Zycos Inc. Immunogenic peptides from the HPV E7 protein
US7569344B2 (en) * 1998-10-26 2009-08-04 Ventana Medical Systems, Inc. Detection of human papilloma virus in papanicolaou (Pap) smears
AU778737B2 (en) * 1999-04-14 2004-12-16 Musc Foundation For Research Development Tissue-specific and pathogen-specific toxic agents and ribozymes
US20050100928A1 (en) * 1999-09-16 2005-05-12 Zycos Inc., A Delaware Corporation Nucleic acids encoding polyepitope polypeptides
US20060275784A1 (en) * 1999-10-26 2006-12-07 Ventana Medical Systems, Inc. Detection of Human Papilloma Virus in Papanicolaou (Pap) Smears
AU2001256976A1 (en) * 2000-04-03 2001-10-15 Cytyc Corporation Detection and typing of human papillomavirus using pna probes
US6936443B2 (en) * 2000-04-03 2005-08-30 Cytyc Corporation Detection and typing of human papillomavirus using PNA probes
US20040229298A1 (en) * 2000-11-11 2004-11-18 Lu Peter S. Methods and compositions for treating cervical cancer
US7312041B2 (en) * 2001-02-16 2007-12-25 Arbor Vita Corporation Methods of diagnosing cervical cancer
US20030059806A1 (en) * 2001-01-05 2003-03-27 Science & Technology Corporation @ Unm Probes for the detection of human papillomavirus
EP2272988A3 (en) 2002-01-07 2011-06-15 Norchip A/S Method for detecting human papillomavirus mRNA
HUP0200981A3 (en) 2002-03-14 2004-06-28 Genoid Kft Pcr reactions with hybridizing probes using primers with broad genotype-specificity for detection of human papilloma-viruses and typing amplificates by using specifically hybridizing oligonucleotides
US7704965B2 (en) * 2002-06-26 2010-04-27 The Penn State Research Foundation Methods and materials for treating human papillomavirus infections
DE60325382D1 (de) 2002-09-09 2009-01-29 Arbor Vita Corp Verfahren zur diagnose von gebärmutterhalskrebs
WO2004037175A2 (en) * 2002-10-21 2004-05-06 Mgi Pharma Biologics, Inc. Compositions and methods for treating human papillomavirus-mediated disease
AU2004275865B2 (en) 2003-09-25 2008-09-25 Third Wave Technologies, Inc. Detection of HPV
AU2004308964B2 (en) * 2003-12-23 2010-09-16 Arbor Vita Corporation Antibodies for oncogenic strains of HPV and methods of their use
CA2588581C (en) 2004-12-08 2011-05-31 Gen-Probe Incorporated Detection of nucleic acids from multiple types of human papillomaviruses
EP1833985B1 (en) * 2004-12-10 2014-08-27 Genera Biosystems Limited Human papilloma virus (hpv) detection using nucleic acid probes, microbeads and fluorescent-activated cell sorter (facs)
EP1853307B1 (en) 2005-02-01 2016-12-14 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, the Department of Health and Human Services, Papillomavirus L2 N-terminal peptides for the induction of broadly cross-neutralizing antibodies
US20070031826A1 (en) * 2005-08-05 2007-02-08 My Gene Diagnostic kit for determining the genotype of a human papilloma virus and method of using thereof
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US7732166B2 (en) * 2005-11-15 2010-06-08 Oncohealth Corporation Detection method for human pappilomavirus (HPV) and its application in cervical cancer
US8080643B2 (en) * 2006-09-05 2011-12-20 Third Wave Technologies, Inc. HPV primers
US20100003704A1 (en) 2008-06-13 2010-01-07 Shuling Cheng IN SITU detection of early stages and late stages HPV infection
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
AU2008236678B2 (en) * 2007-04-05 2013-09-12 Genera Biosystems Limited Compositions and methods of detection
US8980562B1 (en) 2007-06-12 2015-03-17 Physicians Reference Laboratory Method of simultaneous detection and typing of human papilloma viruses
JP2012526286A (ja) 2009-05-07 2012-10-25 オンコヘルス コーポレーション ヒトパピローマウイルス（ｈｐｖ）およびｈｐｖ関連癌の初期段階および後期段階の検出、スクリーニング、および診断のための高度または≧ｃｉｎ２の同定
JP5819851B2 (ja) 2010-01-08 2015-11-24 オンコヘルス コーポレーション Ｈｐｖ関連の癌の治療及びスクリーニングのための細胞に基づいた高処理能力ｈｐｖ免疫アッセイ
AU2011210748A1 (en) 2010-01-29 2012-08-09 Qiagen Gaithersburg, Inc. Method of determining and confirming the presence of HPV in a sample
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー． 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
CN102229660B (zh) * 2011-05-25 2015-04-22 厦门大学 截短的人乳头瘤病毒33型l1蛋白
CN104076150A (zh) * 2013-03-28 2014-10-01 沈萍萍 一种hpv-e6蛋白的检测方法
US9936943B1 (en) 2014-08-07 2018-04-10 Nicholas MANCINI Suture passing surgical device with atraumatic grasper preventing accidental perforations

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
US4419446A (en) * 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
FR2524487B1 (fr) * 1982-04-05 1985-11-22 Pasteur Institut Fragments d'adn codant pour des polypeptides contenant au moins un determinant antigenique des papillomavirus, notamment du type hpv 1a et polypeptides correspondants
JPS6089755A (ja) * 1983-07-01 1985-05-20 フイリツプ・ジヨン・ベア−ド 診断用試薬及びその製造法並びにそれを用いる診断法
US5411857A (en) * 1985-07-31 1995-05-02 Institut Nationale De La Sante Probes for papillomaviruses and an in vitro diagnostic procedure for papilloma infections
CA1276575C (fr) * 1984-11-30 1990-11-20 Sylvie Beaudenon Sondes a papillomavirus et procede de diagnostic in vitro d'infections a papillomavirus
EP0217919B1 (en) * 1985-04-04 1992-08-05 Georgetown University Type-specific papillomavirus dna sequences and peptides
FR2586428B1 (fr) * 1985-08-26 1988-11-25 Pasteur Institut Polypeptides et anticorps, caracteristiques du papillomavirus et leurs applications au diagnostic in vitro, a la prevention et/ou la lutte contre des infections a papillomavirus
WO1987005630A1 (en) * 1986-03-21 1987-09-24 Institut Pasteur Determined dna sequences derived from a papillomavirus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions
US4849322A (en) * 1986-04-30 1989-07-18 E. I. Du Pont De Nemours And Company Positive-working color proofing film and process
DE3625257A1 (de) * 1986-07-23 1988-02-04 Behringwerke Ag Expressionsprodukte der menschlichen papillomviren typ 16 und 18, fuer diese proteine spezifische antikoerper und diese antikoerper bzw. entsprechende dna enthaltende diagnostika
US4849331A (en) * 1987-06-09 1989-07-18 Life Technologies, Inc. Human papillomavirus 44 nucleic acid hybridization probes and methods for employing the same
US4849334A (en) * 1987-06-09 1989-07-18 Life Technologies, Inc. Human papillomavirus 43 nucleic acid hybridization probes and methods for employing the same
US4849332A (en) * 1987-05-26 1989-07-18 Life Technologies, Inc. Human papillomavirus 35 nucleic acid hybridization probes and methods for employing the same
DE3722967A1 (de) * 1987-07-11 1989-01-19 Behringwerke Ag Monoklonale antikoerper gegen e7-protein des humanen papillomvirus typ 16, verfahren zu ihrer herstellung sowie ihre verwendung
FR2629458B2 (fr) * 1987-07-31 1991-08-09 Ire Celltarg Sa Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain
US5182377A (en) * 1988-09-09 1993-01-26 Hoffmann-La Roche Inc. Probes for detection of human papillomavirus
DE3935592A1 (de) * 1989-10-26 1991-05-02 Hella Kg Hueck & Co Verfahren und einrichtung zur regelung der innenraumtemperatur von kraftfahrzeugen
EP0662518B1 (en) * 1989-12-01 2001-11-07 VYSIS, Inc. Nucleic acid probes for detection of HPV transcripts
FR2663040B1 (fr) * 1990-06-11 1995-09-15 Bio Merieux Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich.
CA2052413C (en) * 1990-09-28 2004-07-13 Jeffrey L. Joseph Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods
IT1244462B (it) * 1990-12-06 1994-07-15 Sclavo Spa Oligonucleotidi sintetici utili per la diagnosi di infezione da tipi diversi di virus del gruppo papilloma e loro utilizzazione

Also Published As

Publication number Publication date
AU7200787A (en) 1987-10-09
DK605987D0 (da) 1987-11-18
WO1987005630A1 (en) 1987-09-24
DK605987A (da) 1987-11-18
AU615159B2 (en) 1991-09-26
JPH09117294A (ja) 1997-05-06
US5554538A (en) 1996-09-10
US7063963B2 (en) 2006-06-20
US20040132012A1 (en) 2004-07-08
US6242250B1 (en) 2001-06-05
NO874750D0 (no) 1987-11-13
NO874750L (no) 1987-11-13
US6107086A (en) 2000-08-22
US5648459A (en) 1997-07-15
US20010049137A1 (en) 2001-12-06
FI875082A0 (fi) 1987-11-17
GR3005272T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-05-24
FI100057B (fi) 1997-09-15
JPS63502798A (ja) 1988-10-20
ATE76429T1 (de) 1992-06-15
EP0243221B1 (en) 1992-05-20
DK175314B1 (da) 2004-08-16
US5876723A (en) 1999-03-02
ES2039254T3 (es) 1995-04-01
EP0243221A1 (en) 1987-10-28
DE3779175D1 (de) 1992-06-25
FI875082A7 (fi) 1987-11-17
JP2735537B2 (ja) 1998-04-02
US6344314B2 (en) 2002-02-05
JP2633275B2 (ja) 1997-07-23
NO303287B1 (no) 1998-06-22

Similar Documents

Publication Publication Date Title
KR930007580B1 (ko) 유두종 비루스 게놈으로부터 유도된 결정 dna 서열, 그의 시험관내 진단 목적용 용도 및 항원 조성물의 제조 방법
Cole et al. Genome organization and nucleotide sequence of human papillomavirus type 33, which is associated with cervical cancer
JP2872582B2 (ja) 型特異的乳頭腫ウイルスｄｎａ配列およびペプチド
Seif et al. The genome of human papovavirus BKV
KR0164215B1 (ko) 사람 유두종바이러스 제16형 e7 단백질상의 면역원성 서열을 갖는 폴리펩타이드
JP3207389B2 (ja) 乳頭腫ウィルス及びその診断方法
KR970703425A (ko) G형 간염 바이러스 및 이것의 분자 클로닝 방법(hepatitis g virus and mo-lecular cloning thereof)
Loeber et al. Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen
JPH09501568A (ja) 腫瘍サプレッサ蛋白質ｐｒｂ２、関連遺伝子産生物およびそれをコードするｄｎａ
JP3140773B2 (ja) ウイルスの検出に関する改良
US20070092936A1 (en) Severe acute respiratory syndrome
Davies et al. Definition of murine T helper cell determinants in the major capsid protein of human papillomavirus type 16
WO2012089742A2 (en) IDENTIFICATION OF A NOVEL HUMAN POLYOMAVIRUS (IPPyV) AND APPLICATIONS
US6413522B1 (en) Papilloma viruses, products for the detection thereof as well as for treating diseases caused by them
US6610303B1 (en) Papilloma viruses, products for the detection thereof as well as for treating diseases caused by them
US7105165B2 (en) Mutant human hepatitis B viral strain and uses thereof
Pelletier et al. Characterization of the poliovirus 147S particle: new insights into poliovirus uncoating
CA1341100C (en) Determined dna sequences derived from a papilloma virus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions
JPH02500326A (ja) ヒトｂ親リンパ性ウイルス（ｈｂｌｖ）の分子クローニング及びクローン類
Susloparov et al. Recombinant Antigens of the Epstein-Barr Virus: Design and Investigation of Immunochemical Characteristics

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19871120

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19900629

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19871120

Comment text: Patent Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19920922

Patent event code: PE09021S01D

G160 Decision to publish patent application
PG1605 Publication of application before grant of patent

Comment text: Decision on Publication of Application

Patent event code: PG16051S01I

Patent event date: 19930721

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 19931019

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 19940112

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 19940112

End annual number: 3

Start annual number: 1

PR1001 Payment of annual fee

Payment date: 19960828

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 19970725

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 19980724

Start annual number: 6

End annual number: 6

PR1001 Payment of annual fee

Payment date: 19990727

Start annual number: 7

End annual number: 7

PR1001 Payment of annual fee

Payment date: 20000715

Start annual number: 8

End annual number: 8

PR1001 Payment of annual fee

Payment date: 20010719

Start annual number: 9

End annual number: 9

PR1001 Payment of annual fee

Payment date: 20020718

Start annual number: 10

End annual number: 10

PR1001 Payment of annual fee

Payment date: 20030807

Start annual number: 11

End annual number: 11

PR1001 Payment of annual fee

Payment date: 20040714

Start annual number: 12

End annual number: 12

PR1001 Payment of annual fee

Payment date: 20050708

Start annual number: 13

End annual number: 13

FPAY Annual fee payment

Payment date: 20060710

Year of fee payment: 14

PR1001 Payment of annual fee

Payment date: 20060710

Start annual number: 14

End annual number: 14

EXPY Expiration of term
PC1801 Expiration of term