KR910006727A - 친수성 적층 다공막 및 이의 제조방법 - Google Patents

친수성 적층 다공막 및 이의 제조방법 Download PDF

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KR910006727A
KR910006727A KR1019900015190A KR900015190A KR910006727A KR 910006727 A KR910006727 A KR 910006727A KR 1019900015190 A KR1019900015190 A KR 1019900015190A KR 900015190 A KR900015190 A KR 900015190A KR 910006727 A KR910006727 A KR 910006727A
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South Korea
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membrane
porous membrane
sulfonic acid
contacting
sample
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KR1019900015190A
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KR0131317B1 (ko
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환 칭 싼
케이. 찌우 텅-훼이
자쿨라 도로시
고돈 줄리안
어빈 스팀슨 도날드
자운 피터
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폴 이. 로지
애보트 래보러토리즈
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Publication of KR0131317B1 publication Critical patent/KR0131317B1/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Laminated Bodies (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)

Abstract

내용 없음

Description

친수성 적층 다공막 및 이의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 한면에 적층된, 본 발명에 따른 다공막을 도시한다,
제2도는 양면에 적층된, 본 발명에 따른 다공막을 도시한다,
제3도는 다공막을 도포하기 전의 단층을 도시한다.

Claims (15)

  1. 활성을 유지시키는 생물학적 활성 시약과 접촉시키고; 적어도 한면의 지지체에 수용매계 접착제를 사용하여 적층시킨 다공막을 포함함을 특징으로하는 진단분석시 유용한 고상 장치.
  2. 제1항에 있어서, 다공막이 니트로셀룰로오즈를 포함하는 장치.
  3. 제1항에 있어서, 다공막이 폴리비닐리덴 디플루오라이드를 포함하는 장치.
  4. 제2항에 있어서, 접착제가 어드히시브 리서치(Adhesive Rescarch) 접착제 AS73을 포함하는 장치.
  5. 제1항에 있어서, 다공막에 계면활성제를 삽입시킨 장치.
  6. 제5항에 있어서, 계면활성제가 알킬 설페이트 또는 알킬 설폰산(여기서, 알킬쇄의 탄소수는 1 내지 12이다)을 포함하는 장치.
  7. 제6항에 있어서, 계면활성제가 1-펜탄 설폰산, 1-헵탄 설폰산, 1-옥탄 설폰산, 1-데칸 설폰산, 1-도데칸 설폰산 및 도데실 설페이트로 이루어진 그룹중에서 선택되는 장치.
  8. 제1항에 있어서, 막의 양면을 수용매계 접착제를 사용하여 적층시킨 장치.
  9. (a) 농도가 약 0.01 내지 약 10%(w/w)인 계면활성제가 혼입된 다공막을 수용매계 접착제를 사용하여 지지체에 적층시키고; (b)다공막상에서 국한된 부위를 막에 활성을 유지시키는 생물학적 활성 시약과 접촉시키는 단계를 포함함을 특징으로 하여, 분석물의 존재 또는 양을 측정하기 위한 진단분석시 유용한 습윤성 고상 적층지지체를 제조하는 방법.
  10. 제9항에 있어서, 계면활성제가 알킬 설페이트 또는 알킬 설폰산을 포함하는 방법.
  11. 제9항에 있어서, 수용매계 접착제를 수용하여 다공막의 반대면을 적층시키는 단계를 추가로 포함하는 방법.
  12. (a) 리간드를 결합시킬 수 잇는 리간드 수용체를 습윤성 다공막에서 국한된 부위에 고정시키고(이때, 막은 수용매계 접착제를 사용하여 지지체에 적층되고, 농도가 약 0.01 내지 약 10%(w/w)인 계면활성제가 막에 혼입된다); (b) 단계 (a)의 막에서 국한된 부위를 샘플과 접촉시켜 리간드-리간드 수용체 복합체를 막에 형성시키고; (c)분석물의 측정치로서 복합체의 존재 또는 양을 검출하는 단계를 포함함을 특징으로 하여, 습윤성 고상 다공막을 사용하여 샘플중에서의 특이하게 결합한 리간드의 존재 또는 양을 측정하는 방법.
  13. 제12항에 있어서, 접촉시키는 단계(b)가 막을 샘플에 침지시키는 단계를 포함하는 방법.
  14. 제12항에 있어서, 접촉시키는 단계(b)가 막의 한 말단부를 샘플과 접촉시키고 샘플을 막을 통해 위킹시켜 샘플을 국한된 부위와 접촉시키는 단계를 포함하는 방법.
  15. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900015190A 1989-09-27 1990-09-25 친수성 적충 다공막, 이의 제조방법 및 이를 포함하는 고체상 장치 KR0131317B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41351989A 1989-09-27 1989-09-27
US413519 1995-03-30

Publications (2)

Publication Number Publication Date
KR910006727A true KR910006727A (ko) 1991-04-29
KR0131317B1 KR0131317B1 (ko) 1998-04-11

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KR1019900015190A KR0131317B1 (ko) 1989-09-27 1990-09-25 친수성 적충 다공막, 이의 제조방법 및 이를 포함하는 고체상 장치

Country Status (10)

Country Link
EP (1) EP0420021B1 (ko)
JP (1) JP2820785B2 (ko)
KR (1) KR0131317B1 (ko)
AT (1) ATE140537T1 (ko)
AU (1) AU630236B2 (ko)
CA (1) CA2025476A1 (ko)
DE (1) DE69027826T2 (ko)
DK (1) DK0420021T3 (ko)
ES (1) ES2091782T3 (ko)
GR (1) GR3020887T3 (ko)

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CN102388310B (zh) 2009-04-09 2014-07-16 爱科来株式会社 抑制展开部件的液体浸透性降低的方法
CN108882784B (zh) 2015-10-21 2021-08-03 帕瓦贸易有限公司 用于爱好设备的箱子或罩子
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Also Published As

Publication number Publication date
DE69027826D1 (de) 1996-08-22
CA2025476A1 (en) 1991-03-28
DK0420021T3 (da) 1996-11-25
ES2091782T3 (es) 1996-11-16
DE69027826T2 (de) 1997-02-13
AU6323490A (en) 1991-04-11
JPH03120468A (ja) 1991-05-22
KR0131317B1 (ko) 1998-04-11
AU630236B2 (en) 1992-10-22
ATE140537T1 (de) 1996-08-15
GR3020887T3 (en) 1996-11-30
EP0420021A3 (en) 1991-12-18
EP0420021A2 (en) 1991-04-03
EP0420021B1 (en) 1996-07-17
JP2820785B2 (ja) 1998-11-05

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