ES2037721T3 - Tira de inmunoseparacion. - Google Patents

Tira de inmunoseparacion.

Info

Publication number
ES2037721T3
ES2037721T3 ES87307776T ES87307776T ES2037721T3 ES 2037721 T3 ES2037721 T3 ES 2037721T3 ES 87307776 T ES87307776 T ES 87307776T ES 87307776 T ES87307776 T ES 87307776T ES 2037721 T3 ES2037721 T3 ES 2037721T3
Authority
ES
Spain
Prior art keywords
porous material
area
analyte
receiver
test solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87307776T
Other languages
English (en)
Inventor
John D Olson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/904,597 external-priority patent/US4959307A/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2037721T3 publication Critical patent/ES2037721T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates

Abstract

SE DETALLA UN METODO Y DISPOSITIVO PARA DETERMINAR LA PRESENCIA DE UN ANALITO EN UNA MUESTRA DE LA QUE SE SOSPECHA QUE ESTA CONTAMINADO. EL METODO CONSISTE EN PONER EN CONTACTO UNA SOLUCION DE PRUEBA CONTENIENDO LA MUESTRA, UN ANTICUERPO PARA DICHO ANALITO Y UN CONJUGADO DEL ANALITO, ASI COMO UNA ETIQUETA CON UNA POSICION DE CONTACTO HECHO DE MATERIAL POROSO CAPAZ DE SER ATRAVESADO EN AL MENOS UNA DIRECCION POR LA SOLUCION DE PRUEBA POR MEDIO DE LA CAPILARIDAD. EL MATERIAL POROSO, CONTIENE UN PRIMER RECEPTOR CAPAZ DE LIGAR AL CONJUGADO. EL PRIMER RECEPTOR ESTA LIMITADO NO DIFUSIVAMENTE A UN AREA SOBRE EL MATERIAL POROSO SEPARADA DE LA ZONA DE CONTACTO. EL MATERIAL POROSO CONTIENE ADEMAS UN SEGUNDO RECEPTOR CAPAZ DE LIGAR EL ANTICUERPO AL ANALITO ENTRE LAS DOS AREAS MENCIONADAS. EL SEGUNDO RECEPTOR ESTA LIMITADO NO DIFUSIVAMENTE AL MATERIAL POROSO. AL MENOS UNA PORCION DE LA SOLUCION DE PRUEBA SE LE PERMITE ATRAVESAR EL MATERIAL POROSO POR CAPILARIDAD Y ENTRAR EN CONTACTO CON EL AREA DELPRIMER RECEPTOR. ESTA AREA SE EXAMINA EN PRESENCIA DEL CONJUGADO. CON ESTE FIN, ESTA AREA SE PUEDE EXPONER A UNA SEÑAL QUE PRODUZCA ELEMENTOS CAPAZ DE INTERACCIONAR CON LA ETIQUETA PARA PRODUCIR UNA SEÑAL EN RELACION A LA CANTIDAD DE ANALITO EN LA SOLUCION DE PRUEBA. SE DETECTA ENTONCES LA SEÑAL PRODUCIDA EN LA MENCIONADA AREA.
ES87307776T 1986-09-05 1987-09-03 Tira de inmunoseparacion. Expired - Lifetime ES2037721T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/904,597 US4959307A (en) 1986-09-05 1986-09-05 Immunoseparating strip
US07/013,615 US4963468A (en) 1986-09-05 1987-02-12 Immunoseparating strip

Publications (1)

Publication Number Publication Date
ES2037721T3 true ES2037721T3 (es) 1995-04-01

Family

ID=26685038

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87307776T Expired - Lifetime ES2037721T3 (es) 1986-09-05 1987-09-03 Tira de inmunoseparacion.

Country Status (5)

Country Link
US (1) US4963468A (es)
EP (1) EP0259157B1 (es)
CA (1) CA1303492C (es)
DE (1) DE3776041D1 (es)
ES (1) ES2037721T3 (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
EP0271204A3 (en) * 1986-11-07 1989-10-25 Syntex (U.S.A.) Inc. Immunochromatographic method and device
EP1555529A3 (en) 1987-04-27 2008-06-04 Inverness Medical Switzerland GmbH Immunochromatographic specific binding assay device and method.
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5376556A (en) * 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
US5143852A (en) * 1990-09-14 1992-09-01 Biosite Diagnostics, Inc. Antibodies to ligand analogues and their utility in ligand-receptor assays
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5468648A (en) * 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
US5607863A (en) * 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5869345A (en) 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
EP0623214A1 (en) * 1992-01-17 1994-11-09 Selective Antibodies Limited Determination of haptens
US5707818A (en) * 1994-12-13 1998-01-13 Bsi Corporation Device and method for simultaneously performing multiple competitive immunoassays
US6319676B1 (en) * 1995-05-02 2001-11-20 Carter Wallace, Inc. Diagnostic detection device and method
US6001658A (en) * 1996-09-13 1999-12-14 Diagnostic Chemicals Limited Test strip apparatus and method for determining presence of analyte in a fluid sample
US5798273A (en) * 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6258548B1 (en) 1997-06-05 2001-07-10 A-Fem Medical Corporation Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules
US6194222B1 (en) 1998-01-05 2001-02-27 Biosite Diagnostics, Inc. Methods for monitoring the status of assays and immunoassays
US7713703B1 (en) 2000-11-13 2010-05-11 Biosite, Inc. Methods for monitoring the status of assays and immunoassays
US7071005B1 (en) 1998-08-24 2006-07-04 Centrus International, Inc. Method and device for concentrating selected groups of microorganisms
US6306665B1 (en) 1999-10-13 2001-10-23 A-Fem Medical Corporation Covalent bonding of molecules to an activated solid phase material
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
US7354776B2 (en) * 2000-12-14 2008-04-08 Strategic Diagnostics Inc. Method of processing and testing powdered samples using immunochromatographic strip tests
AT501069A1 (de) * 2001-08-20 2006-06-15 Walter Ing Pils Vorrichtung und verfahren zum nachweis eines analyten
ATE309544T1 (de) 2002-04-09 2005-11-15 Cholestech Corp Verfahren und vorrichtung zur quantifizierung von lipoprotein-cholesterol hoher dichte
US7238519B2 (en) * 2002-06-07 2007-07-03 Cholestech Corporation Automated immunoassay cassette, apparatus and method
DE60230966D1 (de) * 2002-06-07 2009-03-12 Cholestech Corp Automatisierte Kassette für eine Vorrichtung zur Durchführung von immunoanalytischen Tests und Verfahren zu ihrer Verwendung
WO2005078442A1 (en) * 2004-02-10 2005-08-25 Dantini Daniel C Comprehensive food allergy test
DE602008002825D1 (de) 2007-01-09 2010-11-11 Cholestech Corp Vorrichtung und verfahren zur messung des ldl-assoziierten cholesterols
US9927443B2 (en) 2015-04-10 2018-03-27 Conquerab Inc. Risk assessment for therapeutic drugs
US9903866B2 (en) 2016-04-05 2018-02-27 Conquerab Inc. Portable devices for detection of antibodies against therapeutic drugs

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US3990850A (en) * 1976-01-06 1976-11-09 Akzona Incorporated Diagnostic test card
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
US4055394A (en) * 1976-10-18 1977-10-25 Akzona Incorporated Diagnostic test card
IL51354A (en) * 1977-01-28 1979-07-25 Ames Yissum Ltd Assay method for the quantitative determination of a hapten in aqueous solution
US4160008A (en) * 1978-01-26 1979-07-03 Miles Laboratories, Inc. Multilayered test device for determining the presence of a liquid sample component, and method of use
NL184440C (nl) * 1978-05-17 1989-07-17 Battelle Memorial Institute Proefstrook voor het analyseren van opgeloste stoffen.
US4189304A (en) * 1978-10-27 1980-02-19 Miles Laboratories, Inc. Device and method for detecting myoglobin
US4361537A (en) * 1979-01-12 1982-11-30 Thyroid Diagnostics, Inc. Test device and method for its use
US4235601A (en) * 1979-01-12 1980-11-25 Thyroid Diagnostics, Inc. Test device and method for its use
US4327073A (en) * 1980-04-07 1982-04-27 Huang Henry V Automated method for quantitative analysis of biological fluids
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4384958A (en) * 1982-02-26 1983-05-24 Owens-Illinois, Inc. Thin layer chromatography device and method of making chromatography test
US4434236A (en) * 1982-10-20 1984-02-28 E. I. Du Pont De Nemours & Co. Immunoassay wherein labeled antibody is displaced from immobilized analyte-analogue
WO1984002193A1 (en) * 1982-12-03 1984-06-07 Du Pont Chromogenic support immunoassay
IL70391A0 (en) * 1982-12-08 1984-03-30 Medical Diagnostics Inc Drug abuse test indicator device and method of making same
US4459358A (en) * 1982-12-29 1984-07-10 Polaroid Corporation Multilayer element for analysis
GB8305197D0 (en) * 1983-02-24 1983-03-30 Amersham Int Plc Assay methods
GB8306353D0 (en) * 1983-03-08 1983-04-13 Stuart J F B Monitoring of drug levels
DE3445816C1 (de) * 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
DD230074A1 (de) * 1984-12-20 1985-11-20 Forsch Entwicklung Veb Verfahren und vorrichtung zum erfassen von messwerten von physikalischen groessen
US4740468A (en) * 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone

Also Published As

Publication number Publication date
US4963468A (en) 1990-10-16
CA1303492C (en) 1992-06-16
EP0259157A1 (en) 1988-03-09
DE3776041D1 (de) 1992-02-27
EP0259157B1 (en) 1992-01-15

Similar Documents

Publication Publication Date Title
ES2037721T3 (es) Tira de inmunoseparacion.
BR9814007A (pt) Dispositivo de ensaio cromatográfico e processo para detectar a presença de um analito em uma amostra de sangue
BR9710010A (pt) Dispositivo de análise ou teste cromatográfico e processo para detecção e/ou determinação de um analito em uma amostra.
FI842189A (fi) Testanordning.
ES2069545T3 (es) Ensayo y aparato que utiliza una membrana de flujo lateral y no absorbente.
AR246612A1 (es) Portatestigo para la determinacion analitica de una parte componente de muestra de liquido con ayuda de reactivos inmunologicos,procedimiento para fabricar un estrato de fijacion para el mismo
AR015206A1 (es) APARATO PARA DETERMINAR LA CONCENTRACIoN DE UN COMPONENTE MEDICAMENTE SIGNIFICATIVO DE UN FLUíDO BIOLoGICO Y MÉTODO APLICADO EN EL MISMO.
CO4750615A1 (es) Metodo y equipo para recoger muestras de especimenes liquidos para ensayos analiticos
ES2065334T3 (es) Dispositivo de inmunoensayo.
RU2002113055A (ru) Тестирующая полоска с реагентом для определения содержания анализируемого вещества
ES2059394T3 (es) Metodo y dispositivo inmunocromatograficos cualitativos.
DK1111386T3 (da) Teststrimmel til bestemmelse af en analyt i en flydende pröve
AR016908A1 (es) Dispositivo, equipo y procedimiento para detectar la presencia de por lo menos un componente en una muestra biologica.
ATE80736T1 (de) Transparentes teststreifensystem.
IT219575Z2 (it) Dispositivo per prove analitiche.
ES2116719T3 (es) Dispositivo de analisis de flujo interrumpido.
SE7614183L (sv) Forfarande och anordning ffor graviditetstest
KR910006727A (ko) 친수성 적층 다공막 및 이의 제조방법
ES2112320T3 (es) Procedimientos y reactivos con captura de iones que permiten determinar el contenido en digoxina.
ES2033266T3 (es) Procedimiento y estuche de ensayo para la determinacion de sustancias activas libres en liquidos biologicos.
ES2110408T3 (es) Ensayo para la fosfatasa alcalina osea.
ES2113946T3 (es) Tira de ensayo mejorada.
ATE161332T1 (de) Vorrichtungen zur ausführung von ioneneinfangassays
KR910700461A (ko) 단순 포진 비루스 항원 측정용 세정 조성물, 테스트 키트 및 그 사용법
HUP9901737A2 (hu) Eszköz vizsgálati minták optikai analíziséhez

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 259157

Country of ref document: ES