KR890002204B1 - 퍼플로로탄소 유제, 그의 제법 및 그 유제를 포함하는 수성 약제 조성물 - Google Patents
퍼플로로탄소 유제, 그의 제법 및 그 유제를 포함하는 수성 약제 조성물 Download PDFInfo
- Publication number
- KR890002204B1 KR890002204B1 KR1019830003805A KR830003805A KR890002204B1 KR 890002204 B1 KR890002204 B1 KR 890002204B1 KR 1019830003805 A KR1019830003805 A KR 1019830003805A KR 830003805 A KR830003805 A KR 830003805A KR 890002204 B1 KR890002204 B1 KR 890002204B1
- Authority
- KR
- South Korea
- Prior art keywords
- emulsion
- oxygen
- dispersion
- pharmaceutical composition
- pfc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0468—Liquids non-physiological
- A61M2202/0476—Oxygenated solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40858982A | 1982-08-17 | 1982-08-17 | |
| US408.589 | 1982-08-17 | ||
| US51715083A | 1983-07-25 | 1983-07-25 | |
| US517.150 | 1983-07-25 | ||
| US408589 | 1989-09-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR840005660A KR840005660A (ko) | 1984-11-15 |
| KR890002204B1 true KR890002204B1 (ko) | 1989-06-23 |
Family
ID=27020315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019830003805A Expired KR890002204B1 (ko) | 1982-08-17 | 1983-08-16 | 퍼플로로탄소 유제, 그의 제법 및 그 유제를 포함하는 수성 약제 조성물 |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0105584B1 (https=) |
| JP (1) | JPS59501665A (https=) |
| KR (1) | KR890002204B1 (https=) |
| AU (1) | AU559559B2 (https=) |
| CA (1) | CA1225027A (https=) |
| CH (1) | CH665952A5 (https=) |
| DE (2) | DE3378954D1 (https=) |
| ES (1) | ES8502405A1 (https=) |
| FI (1) | FI841513A0 (https=) |
| GB (1) | GB2134787A (https=) |
| GR (1) | GR79383B (https=) |
| IE (1) | IE55618B1 (https=) |
| IL (1) | IL69505A (https=) |
| NL (1) | NL8320264A (https=) |
| NO (1) | NO841519L (https=) |
| PH (2) | PH25492A (https=) |
| PT (1) | PT77204B (https=) |
| SE (1) | SE8402098L (https=) |
| WO (1) | WO1984000686A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59130813A (ja) * | 1983-01-14 | 1984-07-27 | Green Cross Corp:The | 癌化学療法補助剤 |
| JPS59130812A (ja) * | 1983-01-14 | 1984-07-27 | Green Cross Corp:The | 癌化学療法補助剤 |
| CA1257828A (en) * | 1984-04-16 | 1989-07-25 | William Mccormick | Perfluoro compound dispersions containing reduced amounts of surfactant and process of preparation |
| US4815446A (en) * | 1985-05-09 | 1989-03-28 | Alpha Therapeutic Corporation | Process for treating metastasis of cancerous tumors |
| US4781676A (en) * | 1987-02-20 | 1988-11-01 | Air Products And Chemicals, Inc. | Interstitial administration of perfluorochemical emulsions for reoxygenation of hypoxic tumor cells |
| US4956390A (en) * | 1987-08-25 | 1990-09-11 | Air Products And Chemicals, Inc. | Gas transport employing perfluorobutyldecalin |
| WO1991003267A1 (en) * | 1989-08-28 | 1991-03-21 | Sekins K Michael | Lung cancer hyperthermia via ultrasound and/or convection with perfluorocarbon liquids |
| US5562608A (en) * | 1989-08-28 | 1996-10-08 | Biopulmonics, Inc. | Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation |
| US5518731A (en) * | 1990-09-27 | 1996-05-21 | Allergan, Inc. | Nonaqueous fluorinated drug delivery vehicle suspensions |
| US6458376B1 (en) | 1990-09-27 | 2002-10-01 | Allergan, Inc. | Nonaqueous fluorinated drug delivery suspensions |
| FR2679150A1 (fr) * | 1991-07-17 | 1993-01-22 | Atta | Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations. |
| WO1993018748A1 (en) * | 1992-03-19 | 1993-09-30 | Allergan, Inc. | Compositions comprising a drug delivery vehicle suspended in a nonaqueous fluorinated liquid |
| DE4221268C2 (de) * | 1992-06-26 | 1997-06-12 | Lancaster Group Ag | Verwendung eines Dermatikums zur Unterstützung des Sauerstofftransportes in der Haut |
| DE4221256C2 (de) * | 1992-06-26 | 1997-07-10 | Lancaster Group Ag | Galenische Zusammensetzung für die topische Anwendung |
| US5643601A (en) * | 1992-06-26 | 1997-07-01 | Lancaster Group Ag | Phospholipid-and fluorocarbon-containing cosmetic |
| US5480914A (en) * | 1994-05-06 | 1996-01-02 | Allergan, Inc. | Nonaqueous thixotropic drug delivery suspensions and methods of their use |
| AU4645099A (en) | 1998-07-09 | 2000-02-01 | Yoram Harth | Apparatus and method for efficient high energy photodynamic therapy of acne vulgaris and seborrhea |
| US20040122492A1 (en) | 1999-07-07 | 2004-06-24 | Yoram Harth | Phototherapeutic treatment of skin conditions |
| GB0200721D0 (en) * | 2002-01-14 | 2002-02-27 | Univ Bristol | Toxicity test |
| RU2440158C2 (ru) * | 2010-02-25 | 2012-01-20 | Юрий Александрович Белый | Способ фотодинамической терапии субъектов, страдающих злокачественными опухолями |
| EP2587917A4 (en) * | 2010-07-01 | 2015-05-06 | Mtm Res Llc | FLUORCHEMICAL ANTIFIBROBLAST EMULSION THERAPIES |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3828085A (en) * | 1970-07-09 | 1974-08-06 | Allied Chem | Novel amidoamine oxides |
| US3823091A (en) * | 1971-05-19 | 1974-07-09 | Green Cross Corp | Stable emulsion of fluorocarbon particles |
| US4041086A (en) * | 1972-02-07 | 1977-08-09 | Sun Ventures, Inc. | Process of manufacture of flourinated alkyladamantanes |
| US3911138B1 (en) * | 1973-02-26 | 1996-10-29 | Childrens Hosp Medical Center | Artificial blood and method for supporting oxygen transport in animals |
| JPS5331209B2 (https=) * | 1973-10-05 | 1978-09-01 | ||
| DE2524363A1 (de) * | 1975-06-02 | 1976-12-16 | Boehringer Sohn Ingelheim | Neue pharmazeutische mittel |
| US4105798A (en) * | 1976-07-19 | 1978-08-08 | Sun Ventures, Inc. | Perfluoro polycyclic compounds for use as synthetic blood and perfusion media |
| JPS5331209A (en) * | 1976-09-03 | 1978-03-24 | Hitachi Ltd | Small compressor cylinder for refrigerating machine and production of same |
| IE47132B1 (en) * | 1977-08-19 | 1983-12-28 | Roche Products Ltd | Novel nitroimidazoles and pharmaceutical preparations containing these as well as their manufacture |
| JPS6033367B2 (ja) * | 1978-11-24 | 1985-08-02 | 株式会社ミドリ十字 | 酸素運搬輸液 |
| US4282232A (en) * | 1979-04-26 | 1981-08-04 | Research Corporation | Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof |
| US4252827A (en) * | 1979-05-23 | 1981-02-24 | The Green Cross Corporation | Oxygen-transferable fluorocarbon emulsion |
| GB2070429B (en) * | 1979-06-25 | 1984-05-02 | Suntech | Use of perfluorocarbon as burn treatment |
| CA1181011A (en) * | 1980-05-27 | 1985-01-15 | Robert P. Geyer | Perfluorinated n,n-dimethyl cyclohexylmethylamine and emulsions containing the same |
| GR78151B (https=) * | 1982-04-05 | 1984-09-26 | Alcon Lab Inc |
-
1983
- 1983-08-10 JP JP58502857A patent/JPS59501665A/ja active Pending
- 1983-08-10 DE DE8383304632T patent/DE3378954D1/de not_active Expired
- 1983-08-10 FI FI841513A patent/FI841513A0/fi not_active Application Discontinuation
- 1983-08-10 EP EP83304632A patent/EP0105584B1/en not_active Expired
- 1983-08-10 AU AU19413/83A patent/AU559559B2/en not_active Ceased
- 1983-08-10 DE DE19833390172 patent/DE3390172T1/de not_active Ceased
- 1983-08-10 NL NL8320264A patent/NL8320264A/nl unknown
- 1983-08-10 CH CH2020/84A patent/CH665952A5/de not_active IP Right Cessation
- 1983-08-10 WO PCT/US1983/001237 patent/WO1984000686A1/en not_active Ceased
- 1983-08-10 GB GB08409519A patent/GB2134787A/en not_active Withdrawn
- 1983-08-16 ES ES524972A patent/ES8502405A1/es not_active Expired
- 1983-08-16 CA CA000434734A patent/CA1225027A/en not_active Expired
- 1983-08-16 IL IL69505A patent/IL69505A/xx unknown
- 1983-08-16 PT PT77204A patent/PT77204B/pt not_active IP Right Cessation
- 1983-08-16 KR KR1019830003805A patent/KR890002204B1/ko not_active Expired
- 1983-08-17 IE IE1925/83A patent/IE55618B1/en unknown
- 1983-08-17 PH PH29411A patent/PH25492A/en unknown
- 1983-08-17 GR GR72239A patent/GR79383B/el unknown
-
1984
- 1984-04-16 SE SE8402098A patent/SE8402098L/xx not_active Application Discontinuation
- 1984-04-16 NO NO841519A patent/NO841519L/no unknown
- 1984-05-16 PH PH30682A patent/PH25027A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3378954D1 (en) | 1989-02-23 |
| ES524972A0 (es) | 1985-01-01 |
| PH25027A (en) | 1991-01-28 |
| GR79383B (https=) | 1984-10-22 |
| PH25492A (en) | 1991-07-24 |
| IE55618B1 (en) | 1990-11-21 |
| PT77204B (en) | 1986-02-04 |
| EP0105584A1 (en) | 1984-04-18 |
| FI841513A7 (fi) | 1984-04-16 |
| FI841513L (fi) | 1984-04-16 |
| GB2134787A (en) | 1984-08-22 |
| ES8502405A1 (es) | 1985-01-01 |
| PT77204A (en) | 1983-09-01 |
| IL69505A (en) | 1990-03-19 |
| JPS59501665A (ja) | 1984-10-04 |
| FI841513A0 (fi) | 1984-04-16 |
| SE8402098D0 (sv) | 1984-04-16 |
| IE831925L (en) | 1984-02-17 |
| AU559559B2 (en) | 1987-03-12 |
| CH665952A5 (de) | 1988-06-30 |
| NO841519L (no) | 1984-04-16 |
| IL69505A0 (en) | 1983-11-30 |
| EP0105584B1 (en) | 1989-01-18 |
| WO1984000686A1 (en) | 1984-03-01 |
| CA1225027A (en) | 1987-08-04 |
| DE3390172T1 (de) | 1984-11-29 |
| KR840005660A (ko) | 1984-11-15 |
| NL8320264A (nl) | 1984-07-02 |
| SE8402098L (sv) | 1984-04-16 |
| AU1941383A (en) | 1984-03-07 |
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| BENGMARK | Increased Uptake of 5-FU in Experimental Liver Tumours by Simultaneous Infusion of Norepinephrine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
St.27 status event code: A-0-1-A10-A12-nap-PA0109 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
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| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
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| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
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| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
St.27 status event code: A-2-2-Q10-Q13-nap-PG1605 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
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| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
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| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1 |
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| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 19920624 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
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