KR890001001B1 - 안정화된 피록시캄 주사용액의 제조방법 - Google Patents

안정화된 피록시캄 주사용액의 제조방법 Download PDF

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Publication number
KR890001001B1
KR890001001B1 KR1019850007399A KR850007399A KR890001001B1 KR 890001001 B1 KR890001001 B1 KR 890001001B1 KR 1019850007399 A KR1019850007399 A KR 1019850007399A KR 850007399 A KR850007399 A KR 850007399A KR 890001001 B1 KR890001001 B1 KR 890001001B1
Authority
KR
South Korea
Prior art keywords
solution
pyroxicam
methylglucamine
solvent
mole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019850007399A
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English (en)
Korean (ko)
Other versions
KR860003013A (ko
Inventor
프라이스 월터
Original Assignee
하인리히 막크 나흐프
게바르트 후크
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 하인리히 막크 나흐프, 게바르트 후크 filed Critical 하인리히 막크 나흐프
Publication of KR860003013A publication Critical patent/KR860003013A/ko
Application granted granted Critical
Publication of KR890001001B1 publication Critical patent/KR890001001B1/ko
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Finger-Pressure Massage (AREA)
KR1019850007399A 1984-10-10 1985-10-08 안정화된 피록시캄 주사용액의 제조방법 Expired KR890001001B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3437232.6 1984-10-10
DE19843437232 DE3437232A1 (de) 1984-10-10 1984-10-10 Stabilisierte injektionsloesungen von piroxicam

Publications (2)

Publication Number Publication Date
KR860003013A KR860003013A (ko) 1986-05-19
KR890001001B1 true KR890001001B1 (ko) 1989-04-18

Family

ID=6247603

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850007399A Expired KR890001001B1 (ko) 1984-10-10 1985-10-08 안정화된 피록시캄 주사용액의 제조방법

Country Status (22)

Country Link
US (1) US4628053A (https=)
EP (1) EP0177870B1 (https=)
JP (1) JPS6191116A (https=)
KR (1) KR890001001B1 (https=)
CN (1) CN85107838B (https=)
AT (1) ATE62416T1 (https=)
AU (1) AU557184B2 (https=)
CA (1) CA1251734A (https=)
DD (1) DD238329A5 (https=)
DE (2) DE3437232A1 (https=)
DK (1) DK165901C (https=)
FI (1) FI84315C (https=)
GR (1) GR852439B (https=)
HU (1) HU195111B (https=)
IE (1) IE58267B1 (https=)
IL (1) IL76624A0 (https=)
NO (1) NO166687C (https=)
NZ (1) NZ213758A (https=)
PH (1) PH23058A (https=)
PT (1) PT81264B (https=)
SU (1) SU1482509A3 (https=)
ZA (1) ZA857783B (https=)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2545910B1 (fr) * 1983-05-11 1988-07-22 Valeo Dispositif pour ameliorer l'efficacite d'un echangeur de chaleur dans un boitier d'une installation de climatisation, et boitier de cette installation
IT1196307B (it) * 1984-10-22 1988-11-16 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam monoidrato
US5807568A (en) * 1994-12-27 1998-09-15 Mcneil-Ppc, Inc. Enhanced delivery of topical compositions containing flurbiprofen
IT1283252B1 (it) * 1996-03-15 1998-04-16 Pulitzer Italiana Soluzioni di piroxicam iniettabili per via parenterale
WO1998001138A1 (fr) * 1996-07-04 1998-01-15 Nippon Kayaku Kabushiki Kaisha Injections de succinate sodique de methylprednisolone
US6136799A (en) * 1998-04-08 2000-10-24 Abbott Laboratories Cosolvent formulations
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US8314124B2 (en) 2004-02-06 2012-11-20 Active Biotech Ab Crystalline salts of quinoline compounds and methods for preparing them
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004021281A1 (de) * 2004-04-29 2005-11-24 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
CA2623201A1 (en) * 2005-09-30 2007-04-12 Boehringer Ingelheim Vetmedica Gmbh Pharmaceutical preparation containing meloxicam
NZ567088A (en) * 2005-10-19 2012-06-29 Teva Pharma Crystals of laquinimod sodium, and process for the manufacture thereof
KR20150065951A (ko) * 2006-06-12 2015-06-15 테바 파마슈티컬 인더스트리즈 리미티드 안정한 라퀴니모드 제제
EP2234485B1 (en) 2007-12-20 2013-11-13 Teva Pharmaceutical Industries, Ltd. Stable laquinimod preparations
KR20110048571A (ko) * 2008-09-03 2011-05-11 테바 파마슈티컬 인더스트리즈 리미티드 면역 기능을 지닌 ２―옥소―１,２―다이하이드로―퀴놀린 조절제
JP5359333B2 (ja) * 2009-02-05 2013-12-04 ゼリア新薬工業株式会社 コロソリン酸含有水性液剤
PL2458992T3 (pl) * 2009-07-30 2016-07-29 Teva Pharma Leczenie choroby Leśniowskiego-Crohna z użyciem lakwinimodu
WO2011019375A1 (en) * 2009-08-10 2011-02-17 Teva Pharmaceutical Industries Ltd. Treatment of bdnf-related disorders using laquinimod
ES3037313T3 (en) 2009-10-12 2025-09-30 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
US20110218191A1 (en) * 2010-03-03 2011-09-08 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long term-treatment of kidney disorders in cats
MX2012010077A (es) 2010-03-03 2012-09-12 Boehringer Ingelheim Vetmed Uso de meloxicam para el tratamiento a largo plazo de trastornos musculoesqueleticos en gatos.
DE102010014290A1 (de) * 2010-04-08 2011-10-13 Hans Otto Meyer zu Spelbrink Mittel zur prophylaktischen und therapeutischen Behandlung von Herpes-Infektionen
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
CA2851525A1 (en) 2011-10-12 2013-04-18 Teva Pharmaceutical Industries Ltd. Treatment of multiple sclerosis with combination of laquinimod and fingolimod
CN104093310A (zh) 2012-02-03 2014-10-08 泰华制药工业有限公司 拉喹莫德用于治疗一线抗TNFα疗法失败的克罗恩氏病患者的用途
TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
EP2916915A4 (en) 2012-11-07 2016-06-22 Teva Pharma LAQUINIMOD AMINE SALTS
US20160046582A1 (en) 2013-03-14 2016-02-18 Teva Pharmaceutical Industries Ltd. Crystals of laquinimod sodium and improved process for the manufacture thereof
KR101749425B1 (ko) * 2015-11-17 2017-06-22 연세대학교 산학협력단 난용성 약물의 서방형 제제
US20190142789A1 (en) * 2017-08-09 2019-05-16 Piedmont Animal Health, Llc Therapeutic formulations and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629650A (https=) * 1967-05-18 1900-01-01
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
DE2602363C2 (de) * 1976-01-22 1984-04-12 Bayer Ag, 5090 Leverkusen Wäßrige, injizierbare Niclofolan- Formulierungen
DE2756113A1 (de) * 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE3217315C2 (de) * 1982-05-08 1986-05-22 Gödecke AG, 1000 Berlin Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten
AT376879B (de) * 1982-10-27 1985-01-10 Gerot Pharmazeutika Verfahren zur herstellung einer injektionsloesung

Also Published As

Publication number Publication date
PT81264A (en) 1985-11-01
DD238329A5 (de) 1986-08-20
AU557184B2 (en) 1986-12-11
CN85107838A (zh) 1986-07-09
PH23058A (en) 1989-03-27
IE852483L (en) 1986-04-10
FI853926L (fi) 1986-04-11
JPS6191116A (ja) 1986-05-09
NO166687C (no) 1991-09-04
US4628053A (en) 1986-12-09
EP0177870A2 (de) 1986-04-16
FI84315C (fi) 1991-11-25
ZA857783B (en) 1987-05-27
DE3582468D1 (de) 1991-05-16
EP0177870B1 (de) 1991-04-10
DK461385D0 (da) 1985-10-09
EP0177870A3 (en) 1987-06-03
DK165901C (da) 1993-06-28
PT81264B (pt) 1988-02-17
KR860003013A (ko) 1986-05-19
NZ213758A (en) 1988-07-28
ATE62416T1 (de) 1991-04-15
NO854011L (no) 1986-04-11
NO166687B (no) 1991-05-21
GR852439B (https=) 1986-02-10
IE58267B1 (en) 1993-08-25
JPH03849B2 (https=) 1991-01-09
HU195111B (en) 1988-04-28
CN85107838B (zh) 1988-08-24
DK165901B (da) 1993-02-08
FI84315B (fi) 1991-08-15
IL76624A0 (en) 1986-02-28
FI853926A0 (fi) 1985-10-09
AU4842185A (en) 1986-04-17
DK461385A (da) 1986-04-11
CA1251734A (en) 1989-03-28
HUT38541A (en) 1986-06-30
SU1482509A3 (ru) 1989-05-23
DE3437232A1 (de) 1986-04-17

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