KR880002087B1 - 항균성 나프티리딘 또는 퀴놀린 화합물의 염 및 그의 제조방법 - Google Patents

항균성 나프티리딘 또는 퀴놀린 화합물의 염 및 그의 제조방법 Download PDF

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Publication number
KR880002087B1
KR880002087B1 KR8202588A KR820002588A KR880002087B1 KR 880002087 B1 KR880002087 B1 KR 880002087B1 KR 8202588 A KR8202588 A KR 8202588A KR 820002588 A KR820002588 A KR 820002588A KR 880002087 B1 KR880002087 B1 KR 880002087B1
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KR
South Korea
Prior art keywords
acid
compound
oxo
dihydro
fluoro
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Expired
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KR8202588A
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Korean (ko)
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KR840000544A (ko
Inventor
프레드릭 미치 토마스
Original Assignee
토마스 디.몰리테르노
워너-람버트 콤파니
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Publication of KR840000544A publication Critical patent/KR840000544A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR8202588A 1981-06-11 1982-06-10 항균성 나프티리딘 또는 퀴놀린 화합물의 염 및 그의 제조방법 Expired KR880002087B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US27260181A 1981-06-11 1981-06-11
US272601 1981-06-11
US272,601 1981-06-11
US33418281A 1981-12-24 1981-12-24
US334,182 1981-12-24
US334182 1981-12-24

Publications (2)

Publication Number Publication Date
KR840000544A KR840000544A (ko) 1984-02-25
KR880002087B1 true KR880002087B1 (ko) 1988-10-15

Family

ID=26955624

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8202588A Expired KR880002087B1 (ko) 1981-06-11 1982-06-10 항균성 나프티리딘 또는 퀴놀린 화합물의 염 및 그의 제조방법

Country Status (17)

Country Link
EP (1) EP0067666B1 (https=)
KR (1) KR880002087B1 (https=)
AU (1) AU551596B2 (https=)
CA (1) CA1191842A (https=)
DD (1) DD202561A5 (https=)
DE (1) DE3267135D1 (https=)
DK (1) DK155998C (https=)
ES (1) ES512969A0 (https=)
FI (1) FI78292C (https=)
GR (1) GR77194B (https=)
HU (1) HU188181B (https=)
IE (1) IE53259B1 (https=)
IL (1) IL66027A (https=)
NO (1) NO157739C (https=)
NZ (1) NZ200908A (https=)
PH (1) PH19091A (https=)
SU (1) SU1192624A3 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3333719A1 (de) * 1983-09-17 1985-04-04 Bayer Ag Loesungen milchsaurer salze von piperazinylchinolon- und piperazinyl-azachinoloncarbonsaeuren
IT1196051B (it) * 1984-03-16 1988-11-10 Schiena Ricerche Composti ad attivita' antibatterica
DE3517709A1 (de) * 1985-01-05 1986-07-10 Bayer Ag Basische zubereitungen von chinoloncarbonsaeuren
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
HUT40429A (en) * 1985-04-29 1986-12-28 Chinoin Gyogyszer Es Vegyeszet Process for production of salts of derivatives of kynolin carbonic acid
DE3525335A1 (de) * 1985-07-16 1987-01-22 Bayer Ag Embonate von chinoloncarbonsaeuren und ihren derivaten
DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
IT1196429B (it) * 1986-07-01 1988-11-16 Mediolanum Farmaceutici Srl Processo per la preparazione di pirido benzotiazine ad attivita' antibatterica e loro sali con acidi solfonici
IL80459A (en) * 1986-10-30 1991-04-15 Abic Ltd Water-soluble adduct of norfloxacin and nicotinic acid
US5188833A (en) * 1987-12-28 1993-02-23 Kyorin Seiyaku Kabushiki Kaisha Freeze-dried pharmaceutical preparations for parenteral use
JPH01175935A (ja) * 1987-12-28 1989-07-12 Kyorin Pharmaceut Co Ltd 凍結乾燥注射剤
US4948894A (en) * 1989-02-21 1990-08-14 American Cyanamid Company 8-fluoro and 7, 8, 10-trifluoro-9-(substituted)-6-oxo-6H-benzo-(C)quinolizine-5-carboxylic acids
KR0159540B1 (ko) * 1992-01-21 1998-12-01 김정순 퀴놀론-카복실산의 염 및 그 함유조성물
ES2127036B1 (es) * 1994-03-21 1999-11-16 Ind Quimica Agropecuaria S A Aducto de norfloxacina soluble en agua.
ES2088742B1 (es) * 1994-06-29 1997-03-16 Salvat Lab Sa Composicion antibiotica de aplicacion otica.
DE19500784A1 (de) * 1995-01-13 1996-07-18 Bayer Ag Enrofloxacin-Injektions- oder Infusionslösungen
MA24500A1 (fr) 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
WO2008127060A1 (en) 2007-04-13 2008-10-23 Dong Wha Pharmaceutical Co. Ltd. Aspartate of 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza- spiro[3.4]oct-6-yl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid, method for preparing the same, and antimicrobial pharmaceutical composition comprising the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR223983A1 (es) * 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
ZA811304B (en) * 1980-03-11 1982-06-30 Warner Lambert Co Pharmaceutical salts of 4'-(9-acridinylamino)methanesulfon-m-anisidide

Also Published As

Publication number Publication date
FI822066A0 (fi) 1982-06-10
FI78292C (fi) 1989-07-10
CA1191842A (en) 1985-08-13
EP0067666B1 (en) 1985-10-30
GR77194B (https=) 1984-09-11
NO157739B (no) 1988-02-01
DD202561A5 (de) 1983-09-21
AU551596B2 (en) 1986-05-08
NO821931L (no) 1982-12-13
IL66027A (en) 1986-02-28
ES8304117A1 (es) 1983-02-16
NO157739C (no) 1988-05-11
NZ200908A (en) 1984-09-28
EP0067666A1 (en) 1982-12-22
DE3267135D1 (en) 1985-12-05
KR840000544A (ko) 1984-02-25
IL66027A0 (en) 1982-09-30
SU1192624A3 (ru) 1985-11-15
DK155998B (da) 1989-06-12
IE53259B1 (en) 1988-09-28
DK155998C (da) 1989-11-06
PH19091A (en) 1985-12-19
IE821390L (en) 1982-12-11
HU188181B (en) 1986-03-28
AU8475782A (en) 1982-12-16
ES512969A0 (es) 1983-02-16
DK261582A (da) 1982-12-12
FI78292B (fi) 1989-03-31

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